Opportunity Information: Apply for PA 13 142
Apply for PA 13 142
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Acute Kidney Injury in Older Adults (R03)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.866 Aging Research.
- This funding opportunity was created on Mar 14, 2013 and posted on Mar 14, 2013.
- Applicants must submit their applications by May 7, 2016. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $100,000.00 in funding.
- Eligible applicants include: Private institutions of higher education Public and State controlled institutions of higher education Independent school districts State governments Special district governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education County governments Small businesses Public housing authorities/Indian housing authorities City or township governments Others (see text field entitled Additional Information on Eligibility for clarification) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses Native American tribal organizations (other than Federally recognized tribal governments) Native American tribal governments (Federally recognized).
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:
The NIH funding opportunity PA-13-142, titled "Acute Kidney Injury in Older Adults (R03)," is a discretionary grant program designed to support small, focused research projects that improve understanding and care of acute kidney injury (AKI) specifically in older adults. The emphasis is on studies that can be completed in a relatively short time and with limited resources, making it a good fit for pilot projects, feasibility studies, secondary analyses of existing datasets, and other compact, self-contained projects. It also supports work aimed at developing or refining research methods and creating new research technologies relevant to AKI in aging populations.
The scientific scope is broad across the research spectrum, explicitly welcoming basic, clinical, translational, and outcomes research. Applicants are encouraged to propose projects that address key gaps in knowledge about why AKI is increasingly common in older people and what can be done to reduce its immediate and longer-term harms. Studies may be conducted in human subjects and/or in animal models, depending on what best fits the research question.
NIH highlights four main topic areas. First, projects may examine the epidemiology, etiology, and risk factors for AKI in older adults, which could include identifying patient-level vulnerabilities, comorbidities, medication exposures, clinical settings where AKI is most likely to occur, and broader population trends. Second, the FOA invites work on the pathophysiology of AKI in the aging kidney, including how age-related kidney changes alter susceptibility to injury and recovery, and how AKI interacts with chronic kidney disease (CKD) progression and other organ system complications. Third, it encourages research on early detection, diagnosis, and monitoring, such as improved biomarkers, clinical prediction tools, surveillance strategies, or monitoring approaches that can detect AKI earlier or characterize it more accurately in older patients. Fourth, it supports prevention, treatment, and management strategies tailored to older adults, with attention to approaches that can reduce risk, improve recovery, and limit complications during and after an AKI episode.
A defining feature of the opportunity is its outcomes-oriented framing for an older population. NIH is not only interested in short-term clinical outcomes like in-hospital complications and survival, but also in longer-term consequences that are particularly meaningful in later life, including morbidity, mortality, progression or acceleration of CKD, loss of functional independence, and reduced quality of life. The overarching goal is to generate evidence that can guide better diagnosis, prevention, and treatment of AKI in this growing segment of the population, and to clarify the broader health impact of AKI as people age.
From an administrative and eligibility standpoint, this is an NIH grant under the R03 activity code, which is commonly used for small research grants. The award ceiling listed for this opportunity is $100,000, and there is no cost-sharing or matching requirement. The program falls under the health funding activity category and is associated with CFDA 93.866 (Aging Research). A wide range of applicants are eligible, including public and private institutions of higher education, nonprofits (including both 501(c)(3) and certain non-501(c)(3) entities), for-profit organizations, small businesses, school districts, local and state governments, tribal governments and tribal organizations, public housing authorities, and various community-based and faith-based organizations. The eligibility language also explicitly includes U.S. territory entities and non-U.S. (foreign) organizations and institutions, as well as foreign components of U.S. organizations when permitted under NIH policy.
The FOA was posted on March 14, 2013, and the original and final closing date listed is May 7, 2016, with an archive date of June 7, 2016, indicating the opportunity is no longer open for new submissions under that specific announcement number. The full announcement was available via the NIH Grants Guide link provided in the source, and NIH listed the NIH Office of Extramural Research (OER) webmaster contacts for access or linking issues.
FAQs: NIH PA-13-142 - Acute Kidney Injury in Older Adults (R03)
What is PA-13-142?
PA-13-142 is an NIH funding opportunity announcement (FOA) titled "Acute Kidney Injury in Older Adults (R03)." It supports small, focused research projects aimed at improving understanding and care of acute kidney injury (AKI) specifically in older adults.
What type of grant mechanism is this?
This opportunity uses the NIH R03 activity code, which is commonly used for small research grants supporting compact, self-contained projects that can be completed relatively quickly with limited resources.
What is the main goal of this funding opportunity?
The main goal is to generate evidence that can guide better diagnosis, prevention, and treatment of AKI in older adults, and to clarify the broader health impact of AKI as people age.
Is this opportunity currently open?
No. The FOA lists May 7, 2016 as both the original and final closing date, with an archive date of June 7, 2016. That indicates the announcement is no longer open for new submissions under PA-13-142.
How much funding is available per award?
The award ceiling listed for this opportunity is $100,000.
Is cost-sharing or matching required?
No. The opportunity states there is no cost-sharing or matching requirement.
What kinds of projects are a good fit for this R03?
This FOA emphasizes studies that can be completed in a relatively short time and with limited resources. Examples explicitly called out include pilot projects, feasibility studies, secondary analyses of existing datasets, and other small, focused projects. It also supports developing or refining research methods and creating new research technologies relevant to AKI in older adults.
What research areas are eligible (basic, clinical, etc.)?
The scientific scope is broad and welcomes basic, clinical, translational, and outcomes research focused on AKI in older adults.
Do projects have to involve human subjects?
No. The FOA notes that studies may be conducted in human subjects and/or in animal models, depending on what best fits the research question.
What topic areas does NIH highlight for AKI in older adults?
NIH highlights four main topic areas: (1) epidemiology, etiology, and risk factors for AKI in older adults; (2) pathophysiology of AKI in the aging kidney; (3) early detection, diagnosis, and monitoring; and (4) prevention, treatment, and management strategies tailored to older adults.
What kinds of questions fall under epidemiology, etiology, and risk factors?
Projects in this area may focus on identifying patient-level vulnerabilities, comorbidities, medication exposures, clinical settings where AKI is most likely to occur, and broader population trends related to AKI in older people.
What does "pathophysiology of AKI in the aging kidney" mean in this FOA?
It includes studying how age-related kidney changes alter susceptibility to injury and recovery, and how AKI interacts with chronic kidney disease (CKD) progression and other organ system complications.
What kinds of projects fit the early detection, diagnosis, and monitoring focus?
The FOA encourages work on improved biomarkers, clinical prediction tools, surveillance strategies, or monitoring approaches that can detect AKI earlier or characterize it more accurately in older patients.
What kinds of prevention, treatment, or management strategies are of interest?
The FOA supports approaches tailored to older adults that can reduce risk, improve recovery, and limit complications during and after an AKI episode.
What outcomes does NIH care about for AKI in older adults?
NIH is interested in both short-term outcomes (such as in-hospital complications and survival) and longer-term consequences especially meaningful later in life, including morbidity, mortality, progression or acceleration of CKD, loss of functional independence, and reduced quality of life.
What funding activity category is this opportunity associated with?
The program falls under the health funding activity category.
What CFDA number is associated with this opportunity?
This opportunity is associated with CFDA 93.866 (Aging Research).
Who is eligible to apply?
A wide range of applicants are eligible, including public and private institutions of higher education, nonprofits (including 501(c)(3) and certain non-501(c)(3) entities), for-profit organizations, small businesses, school districts, local and state governments, tribal governments and tribal organizations, public housing authorities, and various community-based and faith-based organizations.
Are non-U.S. (foreign) organizations eligible?
Yes. The eligibility language explicitly includes U.S. territory entities and non-U.S. (foreign) organizations and institutions, as well as foreign components of U.S. organizations when permitted under NIH policy.
When was the FOA posted and when did it close?
The FOA was posted on March 14, 2013. The original and final closing date listed is May 7, 2016, and the archive date is June 7, 2016.
Where was the full announcement published?
The full announcement was available via the NIH Grants Guide link referenced in the source information for this opportunity.
Who is listed for technical issues related to access or linking?
NIH listed the NIH Office of Extramural Research (OER) webmaster contacts for access or linking issues.
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