Opportunity Information: Apply for PA 07 396

  • The National Institutes of Health in the health income security and social services sector is offering a public funding opportunity titled "Advanced Tools and Technologies for Deep Brain Stimulation in Movement Disorders SBIR (R43/R44)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.173 Research Related to Deafness and Communication Disorders 93.286 Discovery and Applied Research for Technological Innovations to Improve Human Health 93.853 Extramural Research Programs in the Neurosciences and Neurological Disorders 93.865 Child Health and Human Development Extramural Research 93.866 Aging Research.
  • This funding opportunity was created on Jan 26, 2009 and posted on Jul 12, 2007.
  • Applicants must submit their applications by Multiple Receipt Dates See Link to Full Announcement for details.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Eligible applicants include: Small businesses Others (see text field entitled Additional Information on Eligibility for clarification).
  • Foreign institutions are not eligible to apply.
Apply for PA 07 396

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Opportunity Summary:

The National Institutes of Health (NIH) funding opportunity titled "Advanced Tools and Technologies for Deep Brain Stimulation in Movement Disorders" (Funding Opportunity Number PA-07-396) is a Small Business Innovation Research (SBIR) grant announcement designed to help small businesses create next-generation tools and technologies that improve clinical outcomes for patients receiving Deep Brain Stimulation (DBS). The core goal is practical, patient-centered innovation: advancing the devices, software, methods, or related clinical technologies used in DBS so that treatment for movement disorders can become more effective, safer, easier to deliver, and better tailored to individual patients.

This announcement uses the SBIR grant mechanisms R43/R44 and supports Phase I, Phase II, and Fast Track applications. Phase I is meant to establish feasibility and demonstrate that an idea can be translated into a viable product or technology approach, while Phase II is intended to continue development, validation, and refinement toward a more complete and clinically relevant solution. Fast Track offers a streamlined path for projects ready to move from Phase I into Phase II with minimal delay, which can be important for device and neurotechnology development timelines. NIH notes that this FOA runs in parallel with a companion announcement of the same scientific scope for the Small Business Technology Transfer (STTR) program (PA-07-395; R41/R42). In practice, that means applicants should choose the mechanism that best matches their collaboration structure and business strategy, since SBIR and STTR differ in how research effort is split between the small business and partnering research institutions.

In terms of funding, the opportunity allows relatively substantial support for early-stage and mid-stage development. For Phase I, applicants may request budgets up to $250,000 in total costs per year for up to 2 years. For Phase II, applicants may request budgets up to $500,000 in total costs per year for up to 3 years. NIH emphasizes that awards depend on the availability of funds and the quality and competitiveness of submitted applications, which is standard language but also a reminder that strong technical merit and clear development plans matter. The announcement lists multiple receipt dates rather than a single deadline, indicating that applications could be accepted at several cycles during the active period of the FOA (the full announcement link provides the specific dates that were in effect at the time).

Eligibility is centered on small business concerns, consistent with SBIR requirements, and the opportunity explicitly states that foreign institutions are not eligible to apply. The listing also references that other eligibility nuances may apply (noted by "Others (see text field entitled Additional Information on Eligibility for clarification)"), which typically means applicants should confirm they meet SBIR definitions for a qualifying small business and follow NIH SBIR policy requirements. There is no cost sharing or matching requirement, which lowers the barrier for small businesses that may not have substantial non-federal funds available during early development.

From an administrative and program context perspective, the opportunity is categorized as discretionary funding and uses a grant as the funding instrument. It is associated with several CFDA program areas, reflecting NIH institutes and centers whose missions intersect with DBS, neurotechnology, aging, communication disorders, and broader human health technology innovation. The agency name is NIH, and the posting history shows it was posted July 12, 2007, with later creation metadata and an archive date of May 6, 2010, meaning it is an archived opportunity in the provided record even though it may still be useful as a reference for how NIH framed DBS-focused SBIR solicitations.

Overall, the FOA is essentially an NIH invitation for U.S.-based small businesses to build and advance real-world DBS-enabling technologies for movement disorders under the SBIR program structure, with clear Phase I and Phase II budget caps and durations, and with flexibility to submit as a standard SBIR or as a Fast Track project depending on readiness. For applicants needing more detail, NIH directs users to the full announcement webpage and provides NIH Office of Extramural Research (OER) webmaster contact information for access or linking issues.

Frequently Asked Questions (FAQs)

What is the name of this NIH funding opportunity?

The funding opportunity is titled "Advanced Tools and Technologies for Deep Brain Stimulation in Movement Disorders."

What is the Funding Opportunity Number (FOA number)?

The Funding Opportunity Number is PA-07-396.

Which federal agency is offering this opportunity?

The agency is the National Institutes of Health (NIH).

What type of program is this (SBIR or STTR)?

This announcement is for the Small Business Innovation Research (SBIR) program.

What grant mechanisms does this FOA use?

This FOA uses the SBIR grant mechanisms R43/R44.

Which project phases are supported under this opportunity?

The opportunity supports Phase I, Phase II, and Fast Track applications.

What is the main goal of this funding opportunity?

The core goal is practical, patient-centered innovation to create next-generation tools and technologies that improve clinical outcomes for patients receiving Deep Brain Stimulation (DBS) for movement disorders. The focus is on advancing DBS-related devices, software, methods, or related clinical technologies so treatment can be more effective, safer, easier to deliver, and better tailored to individual patients.

What kinds of projects does NIH want to support through this FOA?

Projects aimed at developing or advancing tools and technologies used in DBS for movement disorders, including devices, software, methods, or related clinical technologies intended to improve outcomes and delivery of DBS in real-world clinical settings.

What is Phase I intended to accomplish?

Phase I is intended to establish feasibility and demonstrate that an idea can be translated into a viable product or technology approach.

What is Phase II intended to accomplish?

Phase II is intended to continue development, validation, and refinement toward a more complete and clinically relevant solution.

What is the Fast Track option?

Fast Track provides a streamlined path for projects that are ready to move from Phase I into Phase II with minimal delay, which can be important for device and neurotechnology development timelines.

Is there a related STTR announcement for the same topic?

Yes. NIH notes this SBIR FOA runs in parallel with a companion announcement of the same scientific scope for the Small Business Technology Transfer (STTR) program: PA-07-395 (R41/R42).

How should an applicant choose between SBIR and STTR for this topic area?

Applicants should choose the mechanism that best matches their collaboration structure and business strategy, since SBIR and STTR differ in how research effort is split between the small business and partnering research institutions.

What is the maximum Phase I budget allowed?

For Phase I, applicants may request budgets up to $250,000 in total costs per year for up to 2 years.

What is the maximum Phase I project duration?

Phase I may be proposed for up to 2 years.

What is the maximum Phase II budget allowed?

For Phase II, applicants may request budgets up to $500,000 in total costs per year for up to 3 years.

What is the maximum Phase II project duration?

Phase II may be proposed for up to 3 years.

Are awards guaranteed if an application meets the budget caps?

No. NIH emphasizes that awards depend on the availability of funds and the quality and competitiveness of submitted applications.

Is cost sharing or matching required?

No. The opportunity states there is no cost sharing or matching requirement.

Who is eligible to apply?

Eligibility is centered on small business concerns consistent with SBIR requirements. The listing also notes that additional eligibility nuances may apply and applicants should confirm they meet SBIR definitions and NIH SBIR policy requirements.

Are foreign institutions eligible to apply?

No. The opportunity explicitly states that foreign institutions are not eligible to apply.

What is the funding instrument for this opportunity?

The funding instrument is a grant.

How is the opportunity categorized in terms of funding type?

It is categorized as discretionary funding.

Are there specific application deadlines?

The announcement lists multiple receipt dates rather than a single deadline, indicating applications could be accepted at several cycles during the active period of the FOA. The full announcement webpage contains the specific dates.

Is this opportunity current or archived?

The provided record indicates it is archived. The posting history shows it was posted July 12, 2007, and the record includes an archive date of May 6, 2010.

Which program areas does this opportunity relate to?

The opportunity is associated with several CFDA program areas reflecting NIH institutes and centers whose missions intersect with DBS, neurotechnology, aging, communication disorders, and broader human health technology innovation.

Where can applicants find the full official announcement and receipt dates?

NIH directs users to the full announcement webpage for complete details, including the specific receipt dates that applied during the active period of the FOA.

Who should be contacted for access or linking issues related to the NIH announcement page?

The information provided references NIH Office of Extramural Research (OER) webmaster contact information for access or linking issues.

Browse more opportunities from the same agency: National Institutes of Health

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Next opportunity: Computational Tools for Research in Neuroscience, Behavioral Science and Mental Health STTR R41/R42

Previous opportunity: Advanced Tools and Technologies for Deep Brain Stimulation in Movement Disorders STTR (R41/R42)

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