Opportunity Information: Apply for PA 10 175
Apply for PA 10 175
- The National Institutes of Health in the health income security and social services sector is offering a public funding opportunity titled "Advanced Tools and Technologies for Deep Brain Stimulation (STTR R41/R42)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.173 Research Related to Deafness and Communication Disorders 93.286 Discovery and Applied Research for Technological Innovations to Improve Human Health 93.853 Extramural Research Programs in the Neurosciences and Neurological Disorders 93.865 Child Health and Human Development Extramural Research 93.866 Aging Research.
- This funding opportunity was created on Apr 27, 2010 and posted on Apr 27, 2010.
- Applicants must submit their applications by May 7, 2013. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Small businesses.
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Opportunity Summary:
The Advanced Tools and Technologies for Deep Brain Stimulation (STTR R41/R42) opportunity (Funding Opportunity Number PA 10 175) is a National Institutes of Health (NIH) funding announcement aimed at helping small businesses build and validate next-generation tools and technologies that can improve clinical treatment outcomes for patients receiving Deep Brain Stimulation (DBS). The core idea is practical, patient-facing innovation: the NIH is looking for engineering and technology development projects that make DBS therapy more effective, safer, more precise, easier to deliver, or otherwise meaningfully better in real clinical settings. Rather than focusing on basic science alone, the emphasis is on designing and developing tangible advances that can translate into improved care for DBS patients.
This announcement uses the Small Business Technology Transfer (STTR) program, meaning projects are expected to involve a formal collaboration between a U.S. small business concern (the applicant organization) and a nonprofit research institution partner, consistent with STTR requirements. Funding is provided through the STTR R41/R42 mechanisms, which cover Phase I (feasibility and proof-of-concept), Phase II (full research and development and further validation), and Fast-Track applications (a combined Phase I/Phase II pathway intended to speed promising projects forward). In parallel, NIH ran a separate but scientifically identical announcement for applicants using the Small Business Innovation Research (SBIR) mechanisms (PA 10 176; R43/R44). In other words, the technical goals and topic area are the same, but the business-research partnering structure differs between STTR and SBIR.
Eligibility is limited to small businesses. There is no cost-sharing or matching requirement, which is important for early-stage technology development because it means applicants are not required to provide a financial match to receive the award. Awards are described as contingent on the availability of funds and on the number of applications that are both submitted and deemed meritorious through peer review. NIH does not commit to a fixed number of awards or a fixed total dollar amount in the summary provided; instead, the actual number of grants and total funding would vary depending on application quality, project duration, and requested budgets.
From an administrative standpoint, this is a discretionary grant opportunity in the Health category (listed as "Health Income Security and Social Services" in the source data). It was posted and created on April 27, 2010. The original and final closing date listed is May 7, 2013, and the opportunity was archived on June 7, 2013, meaning it is no longer open for new applications under that specific announcement number and dates. The program is associated with multiple CFDA numbers that reflect NIH’s relevant research and innovation portfolios, including 93.286 (technological innovations to improve human health) and 93.853 (neurosciences and neurological disorders), among others that touch communication disorders, child health and human development, and aging research. This mix signals that DBS-related technology development can intersect multiple NIH institute missions, such as neurological disease, aging-related conditions, and enabling health technologies.
The full announcement was hosted on the NIH Grants Guide website at the provided link (http://grants.nih.gov/grants/guide/pa-files/PA-10-175.html). For access or technical issues, the contact listed is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV, which is primarily a support contact for difficulties reaching the electronic announcement rather than a scientific program contact.
Frequently Asked Questions (FAQs)
What is the “Advanced Tools and Technologies for Deep Brain Stimulation (STTR R41/R42)†opportunity?
This is a National Institutes of Health (NIH) funding announcement (Funding Opportunity Number PA 10 175) focused on helping small businesses build and validate next-generation tools and technologies that improve clinical treatment outcomes for patients receiving Deep Brain Stimulation (DBS).
What types of projects is NIH trying to fund under this announcement?
The emphasis is on practical, patient-facing engineering and technology development that can make DBS therapy more effective, safer, more precise, easier to deliver, or otherwise meaningfully better in real clinical settings. The announcement prioritizes tangible advances that can translate into improved care rather than basic science alone.
Is this a basic research program or a technology development program?
Based on the description provided, it is primarily a technology development and validation opportunity intended to produce usable advances for clinical DBS treatment, not a basic science-only program.
What funding mechanism does this opportunity use?
This announcement uses the Small Business Technology Transfer (STTR) program and specifically the STTR R41/R42 mechanisms.
What are R41 and R42 in this context?
R41 corresponds to Phase I (feasibility and proof-of-concept). R42 corresponds to Phase II (full research and development and further validation). The announcement also allows Fast-Track applications that combine Phase I and Phase II to help speed promising projects forward.
What is a Fast-Track application under this announcement?
A Fast-Track is a combined Phase I/Phase II application pathway intended to accelerate projects that are positioned to move quickly from feasibility into full development and validation.
Who is eligible to apply?
Eligibility is limited to small businesses.
Does this opportunity require a research partner institution?
Yes. Because it is an STTR opportunity, projects are expected to involve a formal collaboration between a U.S. small business concern (the applicant organization) and a nonprofit research institution partner, consistent with STTR requirements.
Is there a similar NIH opportunity for SBIR instead of STTR?
Yes. NIH ran a separate but scientifically identical announcement for applicants using the Small Business Innovation Research (SBIR) mechanisms: PA 10 176 (R43/R44). The technical goals and topic area are the same, but the partnering structure differs between STTR and SBIR.
Does the announcement require cost-sharing or a matching contribution?
No. The information provided states there is no cost-sharing or matching requirement.
How many awards will NIH make and how much total funding is available?
The summary provided does not commit NIH to a fixed number of awards or a fixed total dollar amount. Awards are described as contingent on the availability of funds and on the number of applications submitted and deemed meritorious through peer review.
What factors affect whether an award is made?
Based on the description, awards depend on available funds and on peer review outcomes (applications must be submitted and judged meritorious). The number of awards and total funding can vary with application quality, project duration, and requested budgets.
What category/type of grant is this?
This is described as a discretionary grant opportunity in the Health category (listed as “Health Income Security and Social Services†in the source data).
When was this opportunity posted and when did it close?
It was posted and created on April 27, 2010. The original and final closing date listed is May 7, 2013.
Is this funding opportunity still open?
No. It was archived on June 7, 2013, meaning it is no longer open for new applications under that specific announcement number and dates.
Where was the full funding announcement published?
The full announcement was hosted on the NIH Grants Guide website at: http://grants.nih.gov/grants/guide/pa-files/PA-10-175.html
What CFDA numbers are associated with this opportunity?
The program is associated with multiple CFDA numbers. The examples explicitly mentioned include 93.286 (technological innovations to improve human health) and 93.853 (neurosciences and neurological disorders), along with others related to communication disorders, child health and human development, and aging research.
What do the multiple CFDA numbers suggest about the scope of DBS technology development?
The mix of CFDA numbers suggests DBS-related technology development can intersect multiple NIH institute missions, including neurological disease, aging-related conditions, and enabling health technologies.
Who is the contact for access or technical issues with the announcement?
The listed contact for access or technical issues is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.
Is the listed contact a scientific/program contact?
No. The information provided indicates this is primarily a support contact for difficulties reaching the electronic announcement, rather than a scientific program contact.
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Applicants also applied for:
Applicants who have applied for this opportunity (PA 10 175) also looked into and applied for these:
| Funding Opportunity |
|---|
| Advanced Tools and Technologies for Deep Brain Stimulation (SBIR R43/R44) Apply for PA 10 176 Funding Number: PA 10 176 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: Case Dependent |
| Ruth L. Kirschstein National Research Service Awards (NRSA) for Individual Predoctoral Fellows in PharmD/PhD Programs (F31) Apply for PA 10 178 Funding Number: PA 10 178 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: Case Dependent |
| Postdoctoral Research Training in Pediatric Clinical and Developmental Pharmacology (T32) Apply for RFA HD 10 005 Funding Number: RFA HD 10 005 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: Case Dependent |
| Vulvodynia Systematic Epidemiologic, Etiologic or Therapeutic Studies (R01) Apply for PAR 10 190 Funding Number: PAR 10 190 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: Case Dependent |
| Vulvodynia Systematic Epidemiologic, Etiologic or Therapeutic Studies (R21) Apply for PAR 10 192 Funding Number: PAR 10 192 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: Case Dependent |
| Vulvodynia Systematic Epidemiologic, Etiologic or Therapeutic Studies (R03) Apply for PAR 10 191 Funding Number: PAR 10 191 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: Case Dependent |
| Natural History of Disorders Identifiable by Newborn Screening (R01) Apply for RFA HD 10 019 Funding Number: RFA HD 10 019 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: $1,000,000 |
| Ruth L. Kirschstein National Research Service Award (NRSA) Institutional Predoctoral Training Program in Systems Biology of Developmental Biology and Birth Defects(T32) Apply for PAR 10 193 Funding Number: PAR 10 193 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: Case Dependent |
| Predoctoral and Postdoctoral Training Program in Reproductive, Obstetric, Perinatal and Pediatric Epidemiology and Pharmacoepidemiology (T32) Apply for PAR 10 194 Funding Number: PAR 10 194 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: Case Dependent |
| Postdoctoral Research Training for Obstetricians and Gynecologists (T32) Apply for PAR 10 203 Funding Number: PAR 10 203 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: Case Dependent |
| Biophysical and Biomechanical Aspects of Embryonic Development (R21) Apply for PAR 10 222 Funding Number: PAR 10 222 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: $200,000 |
| Biophysical and Biomechanical Aspects of Embryonic Development (R01) Apply for PAR 10 221 Funding Number: PAR 10 221 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: Case Dependent |
| Safe and Effective Instruments and Devices for Use in the Neonatal Intensive Care Units (SBIR R43) Apply for RFA HD 10 012 Funding Number: RFA HD 10 012 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: $225,000 |
| Safe and Effective Instruments and Devices for Use in the Neonatal Intensive Care Units (STTR R41) Apply for RFA HD 10 013 Funding Number: RFA HD 10 013 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: $225,000 |
| Innovative Therapies and Tools for Screenable Disorders in Newborns (R03) Apply for PAR 10 231 Funding Number: PAR 10 231 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: Case Dependent |
| Developmental Mechanisms of Human Structural Birth Defects (P01) Apply for RFA HD 10 006 Funding Number: RFA HD 10 006 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: $900,000 |
| NICHD Program Project Grant (P01) Apply for PAR 10 245 Funding Number: PAR 10 245 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: Case Dependent |
| Molecular Mechanisms of Adverse Metabolic Drug Effects in Children and Adolescents (R01) Apply for RFA HD 10 010 Funding Number: RFA HD 10 010 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: $250,000 |
| Dual Purpose with Dual Benefit Research in Biomedicine and Agriculture Using Agriculturally Important Domestic Species (R01) Apply for PAR 10 276 Funding Number: PAR 10 276 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: Case Dependent |
| Identifying and Understanding Effective Interventions for Orphans and Vulnerable Children Affected by HIV/AIDS (R01) Apply for RFA HD 10 017 Funding Number: RFA HD 10 017 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: Case Dependent |
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