Opportunity Information: Apply for PA 16 032
Apply for PA 16 032
- The HHS-NIH11 in the health, income security and social services sector is offering a public funding opportunity titled "Advancing Understanding, Prevention, and Management of Infections Transmitted from Women to their Infants (R01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.865,.
- This funding opportunity was created on Nov 05, 2015 and posted on Nov 05, 2015.
- Applicants must submit their applications by Sep 07, 2019. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Others (see text field entitled Additional Information on Eligibility for clarification).
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Opportunity Summary:
The grant opportunity titled "Advancing Understanding, Prevention, and Management of Infections Transmitted from Women to their Infants (R01)" (Funding Opportunity Number PA 16-032) is a discretionary research grant sponsored by the U.S. Department of Health and Human Services, National Institutes of Health (NIH), specifically associated with NICHD (the Eunice Kennedy Shriver National Institute of Child Health and Human Development). It uses the NIH R01 mechanism, which is intended for substantial, investigator-driven research projects, and it falls under the broad program area of Health, Income Security and Social Services. The CFDA numbers listed for this opportunity are 93.865.
The central goal of this funding opportunity is to expand and strengthen research focused on infections that can be passed from women to their infants, specifically excluding HIV. The FOA emphasizes improving scientific understanding and real-world clinical outcomes for infections transmitted during pregnancy, during labor and delivery, and through breastfeeding. In practical terms, the announcement is looking to spur studies that clarify how these infections spread from mother to child, what puts certain pregnancies or newborns at higher risk, and what interventions can reduce transmission or lessen harm when transmission occurs. NICHD frames this as part of a broader commitment to advancing knowledge and treatments for high-priority perinatal infections, meaning infections that meaningfully affect maternal health, fetal development, neonatal outcomes, and longer-term child health.
The types of research encouraged under this opportunity are broad and include translational, epidemiologic, and clinical research, including clinical studies and clinical trials. Translational research in this context generally means work that helps move insights from basic or laboratory findings into practical tools, diagnostics, preventive strategies, or therapies that can be applied in clinical settings for pregnant people and infants. Epidemiologic studies are relevant because they can map patterns of disease, identify risk factors, and quantify how common particular infections and outcomes are across different populations, settings, and time periods. Clinical studies and trials are highlighted because the FOA is not limited to observation; it explicitly supports intervention-focused work aimed at improving prevention and management, such as evaluating treatments, prophylaxis approaches, screening strategies, or care practices that could change outcomes for mothers and babies.
Eligibility is expansive and includes a wide range of public and private entities. Eligible applicants include state, county, and city or township governments; special district governments; and independent school districts, as well as public and state-controlled institutions of higher education and private institutions of higher education. The FOA also allows applications from federally recognized Native American tribal governments and from Native American tribal organizations that are not themselves federally recognized tribal governments. In addition, it is open to public housing authorities and Indian housing authorities, nonprofit organizations both with and without 501(c)(3) status (as long as they are not institutions of higher education), for-profit organizations other than small businesses, and small businesses. The listing also includes an "Others" category with a note to consult the FOA text for clarifications, signaling that NIH may permit additional applicant types depending on the specific circumstances and requirements described in the full announcement.
In terms of timing and administrative details, the opportunity was created and posted on November 5, 2015. The original closing date and the current closing date are both listed as September 7, 2019, indicating the solicitation window reflected in the provided record. The source data does not specify an award ceiling or the expected number of awards, which often means applicants must consult the full FOA text or NIH guidance for budgeting expectations and programmatic context. Overall, the opportunity is best understood as a call for rigorous, impactful R01-level research that can reduce the burden of non-HIV maternal-to-infant infections by improving prevention strategies and clinical management across the key exposure periods of pregnancy, delivery, and breastfeeding.
Frequently Asked Questions (FAQs)
What is the title of this grant opportunity?
The opportunity is titled "Advancing Understanding, Prevention, and Management of Infections Transmitted from Women to their Infants (R01)."
What is the Funding Opportunity Number (FOA number)?
The Funding Opportunity Number is PA 16-032.
Which federal agency sponsors this grant?
This is a U.S. Department of Health and Human Services (HHS) opportunity administered through the National Institutes of Health (NIH).
Which NIH Institute is associated with this funding opportunity?
The FOA is specifically associated with NICHD (the Eunice Kennedy Shriver National Institute of Child Health and Human Development).
What type of grant mechanism does this opportunity use?
This opportunity uses the NIH R01 mechanism, which is intended for substantial, investigator-driven research projects.
What is the main purpose or goal of this FOA?
The central goal is to expand and strengthen research on infections that can be transmitted from women to their infants (excluding HIV), with an emphasis on improving scientific understanding and real-world clinical outcomes.
Are HIV-related projects eligible under this announcement?
No. The FOA explicitly focuses on infections transmitted from women to infants while specifically excluding HIV.
Which transmission time periods does the FOA focus on?
The FOA emphasizes infections transmitted during pregnancy, during labor and delivery, and through breastfeeding.
What kinds of research topics does the FOA aim to advance?
Based on the description provided, the FOA is looking for studies that clarify how infections spread from mother to child, identify what puts certain pregnancies or newborns at higher risk, and evaluate interventions that can reduce transmission or lessen harm when transmission occurs.
What does NICHD consider "high-priority perinatal infections" in this context?
In this FOA, NICHD frames the topic as perinatal infections that meaningfully affect maternal health, fetal development, neonatal outcomes, and longer-term child health.
What broad types of research are encouraged?
The opportunity encourages a broad range of research, including translational research, epidemiologic research, and clinical research, including clinical studies and clinical trials.
Does this FOA allow clinical studies and clinical trials?
Yes. The description indicates that clinical studies and clinical trials are explicitly included among the supported research types.
What does "translational research" mean for this FOA?
In this context, translational research refers to work that helps move insights from basic or laboratory findings into practical tools, diagnostics, preventive strategies, or therapies that can be used in clinical settings for pregnant people and infants.
Why are epidemiologic studies relevant to this announcement?
Epidemiologic studies are relevant because they can map patterns of disease, identify risk factors, and quantify how common particular infections and outcomes are across different populations, settings, and time periods.
What kinds of interventions are implied as in-scope for clinical research?
The FOA description points to intervention-focused work aimed at improving prevention and management, such as evaluating treatments, prophylaxis approaches, screening strategies, or care practices that could change outcomes for mothers and babies.
What is the CFDA number associated with this opportunity?
The CFDA number listed is 93.865.
What broad program area does this grant fall under?
The record places it under the broad program area of Health, Income Security and Social Services.
Who is eligible to apply?
Eligibility is broad and includes a wide range of public and private entities, including multiple levels of government, institutions of higher education (public and private), tribal governments and certain tribal organizations, housing authorities, nonprofits, for-profits (other than small businesses), and small businesses.
Are state, county, or city/township governments eligible?
Yes. State governments, county governments, and city or township governments are listed as eligible applicants.
Are special district governments and independent school districts eligible?
Yes. Special district governments and independent school districts are included in the eligibility list.
Are universities and colleges eligible to apply?
Yes. Public and state-controlled institutions of higher education and private institutions of higher education are listed as eligible.
Are tribal entities eligible?
Yes. Federally recognized Native American tribal governments are eligible, and Native American tribal organizations that are not federally recognized tribal governments are also listed as eligible.
Are public housing authorities or Indian housing authorities eligible?
Yes. Public housing authorities and Indian housing authorities are explicitly included among eligible applicants.
Are nonprofit organizations eligible?
Yes. Nonprofit organizations with or without 501(c)(3) status are eligible, as long as they are not institutions of higher education (as stated in the provided eligibility description).
Are for-profit organizations eligible?
Yes. For-profit organizations other than small businesses are listed as eligible, and small businesses are also listed as eligible.
What does the "Others" eligibility category mean?
The listing includes an "Others" category with a note to consult the full FOA text for clarifications, which suggests NIH may permit additional applicant types depending on the specific circumstances and requirements described in the full announcement.
When was this opportunity created and posted?
The record indicates it was created and posted on November 5, 2015.
What is the closing date for this opportunity?
Both the original closing date and the current closing date are listed as September 7, 2019.
Does the provided record list an award ceiling (maximum award amount)?
No. The provided source data does not specify an award ceiling.
Does the provided record state the expected number of awards?
No. The provided source data does not specify the expected number of awards.
What should applicants do if they need budgeting expectations or likely award volume?
The description indicates that applicants may need to consult the full FOA text or NIH guidance for budgeting expectations and programmatic context because those details are not included in the provided record.
In one sentence, what is this opportunity best understood as?
It is a call for rigorous, impactful R01-level research to reduce the burden of non-HIV maternal-to-infant infections by improving prevention strategies and clinical management across pregnancy, delivery, and breastfeeding.
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