Opportunity Information: Apply for PA 12 177
Apply for PA 12 177
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Alcohol Abuse, Sleep Disorders and Circadian Rhythms (R01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.273 Alcohol Research Programs.
- This funding opportunity was created on May 3, 2012 and posted on Apr 26, 2012.
- Applicants must submit their applications by May 7, 2015. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Private institutions of higher education For profit organizations other than small businesses City or township governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Special district governments Independent school districts Small businesses State governments County governments Others (see text field entitled Additional Information on Eligibility for clarification) Public and State controlled institutions of higher education Public housing authorities/Indian housing authorities Native American tribal organizations (other than Federally recognized tribal governments) Native American tribal governments (Federally recognized) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
[Watch] Creating a grant proposal using the step-by-step wizard inside the applicant portal:
Opportunity Summary:
The Alcohol Abuse, Sleep Disorders and Circadian Rhythms (R01) opportunity (Funding Opportunity Number PA 12 177) is a discretionary NIH research grant issued by the National Institute on Alcohol Abuse and Alcoholism (NIAAA). Its central purpose is to support Research Project Grant (R01) applications that dig into the underlying biological and physiological mechanisms linking alcohol abuse with sleep disorders and disruptions in circadian rhythms. The emphasis is on mechanistic work, meaning the FOA is looking for studies that move beyond simple correlations and instead test how and why alcohol exposure, alcohol use disorders, or patterns of heavy drinking alter sleep and circadian biology, and how sleep or circadian disruption might in turn influence alcohol-related behaviors and outcomes. The announcement explicitly welcomes research in both human subjects and animal models, signaling that proposals can span clinical, translational, and preclinical approaches as long as they are aimed at understanding causation, pathways, and systems-level interactions.
In practical terms, this FOA fits investigators who want to study questions such as how alcohol affects the timing and quality of sleep, how it changes circadian clock function, and what neural, hormonal, genetic, or molecular pathways may be involved. Because it calls for mechanistic studies, strong applications typically would be expected to include rigorous experimental designs, clear hypotheses about biological mechanisms, and methods suited to measuring sleep and circadian function (for example, physiologic sleep measures, circadian phase assessments, or clock-related molecular markers), as well as alcohol-related endpoints (such as consumption patterns, dependence-relevant phenotypes, withdrawal-related sleep disturbance, relapse vulnerability, or alcohol-induced changes in brain and body systems). The topic area naturally lends itself to work that connects brain circuits, stress and reward pathways, endocrine rhythms, and behavioral regulation, and it also creates space for proposals examining bidirectional effects, such as whether circadian misalignment or chronic insomnia increases risk for problematic drinking, or whether alcohol-driven sleep disruption contributes to escalation of use, impaired functioning, or difficulty maintaining abstinence.
The funding mechanism is an R01, which is NIH's standard research project grant and is typically used to support mature, hypothesis-driven projects with a defined scope of work. The activity category is Health, and the CFDA listing associated with the program is 93.273 (Alcohol Research Programs). There is no cost sharing or matching requirement, so applicants are not required to provide institutional matching funds as a condition of eligibility. The announcement was posted on April 26, 2012, with a creation date of May 3, 2012. The original closing date was June 5, 2015, and the current closing date listed is May 7, 2015, with an archive date of June 7, 2015, which indicates the FOA is historical/archived rather than currently open for new submissions under that exact announcement.
Eligibility is broad and includes a wide range of organizations. Eligible applicants include private and public institutions of higher education (including public/state-controlled universities), nonprofit organizations with and without 501(c)(3) status, for-profit organizations (including small businesses and for-profits other than small businesses), and multiple levels of government entities such as state, county, city/township governments, special district governments, and independent school districts. Public housing authorities and Indian housing authorities are also listed. The FOA further clarifies additional eligible applicants, including Alaska Native and Native Hawaiian Serving Institutions, Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, regional organizations, U.S. territories or possessions, and eligible federal agencies. Importantly, non-U.S. entities are eligible to apply, and foreign components are allowed consistent with the NIH Grants Policy Statement, meaning foreign institutions can apply directly, U.S. organizations can include non-U.S. components, and foreign components are permissible as defined by NIH policy.
Administrative details included in the source information indicate the sponsoring agency is the National Institutes of Health, with NIAAA as the issuing institute. A link to the full announcement was provided through the NIH Grants Guide (http://grants.nih.gov/grants/guide/pa-files/PA-12-177.html). For access or technical issues with the online announcement, the contact point listed is the NIH Office of Extramural Research (OER) webmaster (FBOWebmaster@OD.NIH.GOV), which is intended for troubleshooting problems with accessing or linking to the FOA rather than for scientific or programmatic guidance.
Overall, this FOA was designed to build a stronger mechanistic understanding of how alcohol abuse intersects with sleep pathology and circadian biology, encouraging research that can clarify causal pathways and identify targets for prevention or treatment. By supporting projects in both humans and animal models and by allowing a wide range of applicant organizations, the announcement aimed to bring together basic, translational, and clinical expertise to address a set of interconnected health problems that often reinforce each other in real-world settings.
Frequently Asked Questions (FAQs)
What is the title of this funding opportunity?
The opportunity is titled "Alcohol Abuse, Sleep Disorders and Circadian Rhythms (R01)".
What is the Funding Opportunity Number (FON)?
The Funding Opportunity Number is PA-12-177.
What type of grant mechanism does this opportunity use?
This opportunity uses the NIH Research Project Grant (R01) mechanism, which is NIH's standard grant type for defined, hypothesis-driven research projects.
Which agency and institute are sponsoring this opportunity?
The sponsoring agency is the National Institutes of Health (NIH), and the issuing institute is the National Institute on Alcohol Abuse and Alcoholism (NIAAA).
What is the central purpose of this FOA?
The central purpose is to support R01 applications that investigate the biological and physiological mechanisms linking alcohol abuse with sleep disorders and disruptions in circadian rhythms.
What does the FOA mean by emphasizing "mechanistic" research?
The FOA emphasizes studies that go beyond correlations and instead test how and why alcohol exposure, alcohol use disorders, or heavy drinking patterns alter sleep and circadian biology, and how sleep or circadian disruption may, in turn, influence alcohol-related behaviors and outcomes.
Are human-subjects studies allowed under this announcement?
Yes. The announcement explicitly welcomes research in human subjects.
Are animal-model studies allowed under this announcement?
Yes. The announcement explicitly welcomes research in animal models, supporting preclinical approaches as long as they focus on understanding mechanisms.
What kinds of research questions fit this FOA?
The FOA is intended for projects examining topics such as how alcohol affects the timing and quality of sleep, how alcohol changes circadian clock function, and which neural, hormonal, genetic, or molecular pathways are involved.
Does the FOA support studying bidirectional effects between alcohol and sleep/circadian disruption?
Yes. The FOA creates space for research on bidirectional relationships, such as whether circadian misalignment or chronic insomnia increases risk for problematic drinking, or whether alcohol-driven sleep disruption contributes to escalation of use, impaired functioning, relapse vulnerability, or difficulty maintaining abstinence.
What kinds of measurements or endpoints does the FOA expect projects to include?
Based on the description, strong mechanistic applications would typically include methods suited to measuring sleep and circadian function (for example, physiologic sleep measures, circadian phase assessments, or clock-related molecular markers) and alcohol-related endpoints (such as consumption patterns, dependence-relevant phenotypes, withdrawal-related sleep disturbance, relapse vulnerability, or alcohol-induced changes in brain and body systems).
What is the activity category listed for this opportunity?
The activity category is Health.
What CFDA listing is associated with this program?
The CFDA listing associated with the program is 93.273 (Alcohol Research Programs).
Is cost sharing or matching required?
No. The opportunity states there is no cost sharing or matching requirement, meaning applicants are not required to provide institutional matching funds as a condition of eligibility.
Is this FOA currently open for submissions?
No. The dates indicate the FOA is historical/archived rather than currently open under this exact announcement. The original closing date was June 5, 2015, the current closing date listed is May 7, 2015, and the archive date is June 7, 2015.
When was this funding announcement posted and created?
The announcement was posted on April 26, 2012, with a creation date of May 3, 2012.
What types of organizations are eligible to apply?
Eligibility is broad and includes: private and public institutions of higher education (including public/state-controlled universities), nonprofit organizations with and without 501(c)(3) status, for-profit organizations (including small businesses and for-profits other than small businesses), and various government entities (state, county, city/township, special district governments, and independent school districts), as well as public housing authorities and Indian housing authorities.
Are minority-serving institutions and community-based organizations included as eligible applicants?
Yes. The FOA lists additional eligible applicants including Alaska Native and Native Hawaiian Serving Institutions, Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), and faith-based or community-based organizations, among others.
Are U.S. territories or possessions eligible?
Yes. The FOA lists U.S. territories or possessions among eligible applicants.
Can non-U.S. (foreign) organizations apply?
Yes. The FOA states that non-U.S. entities are eligible to apply.
Are foreign components allowed on applications led by U.S. organizations?
Yes. The FOA allows foreign components consistent with the NIH Grants Policy Statement, meaning U.S. organizations may include non-U.S. components and foreign components are permissible as defined by NIH policy.
Where can applicants find the full announcement text?
The full announcement is available through the NIH Grants Guide at: http://grants.nih.gov/grants/guide/pa-files/PA-12-177.html
Who should be contacted for technical issues accessing the online announcement?
For access or technical problems with the online announcement (such as trouble accessing or linking to the FOA), the listed contact is the NIH Office of Extramural Research (OER) webmaster at FBOWebmaster@OD.NIH.GOV.
Is the listed contact intended for scientific or programmatic questions?
No. The description specifies that this contact point is for troubleshooting issues with accessing or linking to the FOA, not for scientific or programmatic guidance.
Browse more opportunities from the same category: Health
Next opportunity: Conservation Innovation Grants (CIG) Fiscal Year (FY) 2012
Previous opportunity: Alcohol Abuse, Sleep Disorders and Circadian Rhythms (R21)
USGrants.org Applicant Portal:
Are you interested in learning about about how to apply for this government funding opportunity? You can create a free applicant account and receive instant access to our applicant portal that many business owners like you have benefited from.
Apply for PA 12 177
[Watch] how do funding administrators access proposals?
Applicants also applied for:
Applicants who have applied for this opportunity (PA 12 177) also looked into and applied for these:
| Funding Opportunity |
|---|
| Primary and Behavioral Health Care Integration (PPHF 2012) Apply for SM 12 008 Funding Number: SM 12 008 Agency: Substance Abuse Mental Health Services Adminis. Category: Health Funding Amount: $400,000 |
| Enhancing HIV Mobilization among Organizations Serving Gay, Bisexual and other Men Who Have Sex with Men Apply for CDC RFA PS12 1211 Funding Number: CDC RFA PS12 1211 Agency: Centers for Disease Control and Prevention Category: Health Funding Amount: $220,000 |
| Integrated Social Marketing Apply for SOL 687 12 000005 Funding Number: SOL 687 12 000005 Agency: Madagascar USAID Antananarivo Category: Health Funding Amount: $37,000,000 |
| Effect of Physicochemical Properties of Ophthalmic Formulations on Ocular Bioavailability (U01) Apply for RFA FD 12 020 Funding Number: RFA FD 12 020 Agency: Food Drug Administration Category: Health Funding Amount: $500,000 |
| Minority Fellowship Program Apply for SM 12 010 Funding Number: SM 12 010 Agency: Substance Abuse Mental Health Services Adminis. Category: Health Funding Amount: $825,000 |
| Increasing Adolescent Immunization Rates through Healthcare Provider Partnerships Apply for CDC RFA IP12 1202 Funding Number: CDC RFA IP12 1202 Agency: Centers for Disease Control and Prevention Category: Health Funding Amount: $175,000 |
| Increasing Adult Immunization Rates through Healthcare Provider Partnerships Apply for CDC RFA IP12 1205 Funding Number: CDC RFA IP12 1205 Agency: Centers for Disease Control and Prevention Category: Health Funding Amount: $175,000 |
| Mentored Career Award for Faculty at Institutions That Promote Diversity (K01) Apply for RFA HL 13 018 Funding Number: RFA HL 13 018 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Cooperative Agreement for a National Research and Training Organization for People with Developmental and Other Disabilities Apply for CDC RFA DD07 0030501SUPP12 Funding Number: CDC RFA DD07 0030501SUPP12 Agency: Centers for Disease Control and Prevention Category: Health Funding Amount: Case Dependent |
| Part B AIDS Drug Assistance Program (ADAP) Emergency Relief Awards Apply for HRSA 12 177 Funding Number: HRSA 12 177 Agency: Health Resources and Services Administration Category: Health Funding Amount: $7,000,000 |
| Rapid Assessment Post Impact of Disaster (R03) Apply for PAR 12 180 Funding Number: PAR 12 180 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Rapid Assessment Post Impact of Disaster (R21) Apply for PAR 12 181 Funding Number: PAR 12 181 Agency: National Institutes of Health Category: Health Funding Amount: $200,000 |
| National Spina Bifida Initiatives Prevention, Resources, and Quality of Life Apply for CDC RFA DD07 7090501SUPP12 Funding Number: CDC RFA DD07 7090501SUPP12 Agency: Centers for Disease Control and Prevention Category: Health Funding Amount: Case Dependent |
| Comprehensive District Based Support for Better HIV/TB Patient Outcomes Apply for RFA 674 12 000005 Funding Number: RFA 674 12 000005 Agency: South Africa USAID Pretoria Category: Health Funding Amount: $20,000,000 |
| T32 Training Program for Institutions That Promote Diversity (T32) Apply for RFA HL 13 021 Funding Number: RFA HL 13 021 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| FY12 Eliminating Lupus Health Disparities Initiative (ELHDI) Apply for MP CPI 12 001 Funding Number: MP CPI 12 001 Agency: Office of the Assistant Secretary for Health Category: Health Funding Amount: $1,000,000 |
| FY12 Youth Empowerment Program (YEP) Apply for MP YEP 12 001 Funding Number: MP YEP 12 001 Agency: Office of the Assistant Secretary for Health Category: Health Funding Amount: $300,000 |
| FY12 Peer to Peer Outreach Model to Curb HIV/AIDS Transmission Among High Risk Minority Youth and Adolescents (CHAT) Apply for MP HHP 12 001 Funding Number: MP HHP 12 001 Agency: Office of the Assistant Secretary for Health Category: Health Funding Amount: $250,000 |
| FY12 American Indian/Alaska Native Health Disparities Program Apply for MP AIA 12 001 Funding Number: MP AIA 12 001 Agency: Office of the Assistant Secretary for Health Category: Health Funding Amount: $250,000 |
| Health Finance and Governance Project (HFG) Apply for RFA OAA 12 000011 Funding Number: RFA OAA 12 000011 Agency: Agency for International Development Category: Health Funding Amount: $200,000,000 |
Grant application guides and resources
It is always free to apply for government grants. However the process may be very complex depending on the funding opportunity you are applying for. Let us help you!
Apply for Grants
Premium leads for funding administrators, grant writers, and loan issuers
Thousands of people visit our website for their funding needs every day. When a user creates a grant proposal and files for submission, we pass the information on to funding administrators, grant writers, and government loan issuers.
If you manage government grant programs, provide grant writing services, or issue personal or government loans, we can help you reach your audience.
Subscribe to Leads
Request more information:
Would you like to learn more about this funding opportunity, similar opportunities to "PA 12 177", eligibility, application service, and/or application tips? Submit an inquiry below:
Don't forget to subscribe to our grant alerts mailing list to receive weekly alerts on new and updated grant funding opportunities like this one in your email.