Opportunity Information: Apply for 80JSC017N0001 BPBA
Apply for 80JSC017N0001 BPBA
- The National Aeronautics and Space Administration, NASA Johnson Space Center in the science and technology and other research and development sector is offering a public funding opportunity titled "Appendix C: Topics in Biological, Physiological, and Behavioral Adaptations to Spaceflight: Integrated One Year Mission Project and Other Opportunities" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 43.003.
- This funding opportunity was created on Nov 30, 2017.
- Applicants must submit their applications by Jan 04, 2018. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $1,800,000.00 in funding.
- The number of recipients for this funding is limited to 18 candidate(s).
- Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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Opportunity Summary:
This opportunity is a NASA Research Announcement (NRA) from the NASA Johnson Space Center under the Human Exploration Research Opportunities (HERO) umbrella solicitation (80JSC017N0001). Specifically, it is Appendix C, titled "Topics in Biological, Physiological, and Behavioral Adaptations to Spaceflight: Integrated One Year Mission Project and Other Opportunities" (response area number 80JSC017N0001-BPBA). The main purpose is to fund applied research that supports NASA's Human Research Program (HRP) goals, especially research that helps NASA understand, predict, and reduce risks to astronaut health and performance during long-duration missions.
A central focus of Appendix C is the "Analyses of the Temporal Nature of Human Adaptation to Long-Duration Low-Earth Orbit Missions." NASA is looking for studies that characterize how human physiological, psychological, and medical changes unfold over time in space, with an emphasis on whether risks become unacceptable when mission duration extends beyond the more common six-month International Space Station (ISS) expeditions. HRP states that it needs enough direct, one-year flight experience to determine whether harmful effects appear (or do not appear) beyond the current experience base, and to support credible extrapolation to early interplanetary expeditions that could last roughly two to three years.
To enable that research, HRP outlines an integrated One-Year Mission Project (i1YMP) design on the ISS. The planned structure includes five one-year missions involving a total of 10 crewmember subjects, paired with five standard six-month missions (also totaling 10 subjects) that run in parallel with the year-long expeditions, plus five short-duration crew vehicle exchange expeditions (10 subjects) lasting up to about two months each and occurring at the midpoint of each one-year mission. In practical terms, NASA is signaling that it wants proposals that can take advantage of this integrated set of mission durations and comparison groups to study time-dependent adaptation, tipping points, and recovery trajectories, rather than treating long-duration spaceflight effects as a single before-and-after outcome.
Beyond the integrated one-year mission analyses, Appendix C also solicits proposals across several additional biological, physiological, and behavioral research topics tied to exploration mission readiness. These include studies of the biological, physiological, and behavioral functions of mice exposed to partial gravity levels between 0 and 1 G using centrifugation on the ISS, a topic jointly solicited by HRP and NASA's Space Biology Program. Other solicited areas include developing and testing novel hypotheses and countermeasures for Spaceflight-Associated Neuro-Ocular Syndrome (SANS), advancing medical countermeasures that protect multiple tissues affected by space radiation, and improving human performance through individual and team problem-solving skills training designed for exploration conditions. The appendix also calls for work on sensory stimulation approaches that support cognitive and behavioral health, and for research tied to "Human Capabilities Assessments for Autonomous Missions (HCAAM)," framed as a Virtual NASA Specialized Center of Research, reflecting NASA's interest in assessing and supporting crew capabilities when communication delays and operational autonomy increase during deep-space missions.
From an administrative and funding standpoint, the opportunity is categorized as discretionary and allows multiple award mechanisms, including grants, cooperative agreements, and procurement contracts. The CFDA listing is 43.003. The posted award ceiling is $1,800,000, and NASA anticipated about 18 awards under this appendix. Eligibility is broadly open across U.S. institutions (unrestricted by organizational type), and principal investigators are allowed to collaborate with universities, federal laboratories, private sector partners, and state or local government labs, with the applying organization responsible for overall project management as proposed. NASA also notes that collaborations with non-U.S. organizations may occur only on a cooperative, no-exchange-of-funds basis, meaning NASA funding generally does not flow to foreign partners through this mechanism.
The solicitation used a two-step proposal process. A virtual pre-proposers conference was scheduled for December 11, 2017, with details to be posted on NSPIRES. Step-1 proposals for Appendix C were due January 4, 2018, and Step-2 proposals were due April 4, 2018, by invitation. Additional documents and full appendix details were provided through the HERO BPBA link and the broader NASA HERO research opportunities page, with official submission and updates handled through NSPIRES.
Frequently Asked Questions (FAQs)
What is this funding opportunity?
This opportunity is a NASA Research Announcement (NRA) issued by the NASA Johnson Space Center under the Human Exploration Research Opportunities (HERO) umbrella solicitation (80JSC017N0001). It specifically covers Appendix C: "Topics in Biological, Physiological, and Behavioral Adaptations to Spaceflight: Integrated One Year Mission Project and Other Opportunities" (response area number 80JSC017N0001-BPBA).
What is the main purpose of Appendix C?
The purpose is to fund applied research that supports NASA's Human Research Program (HRP) goals, with an emphasis on improving NASA's ability to understand, predict, and reduce risks to astronaut health and performance during long-duration missions.
Which NASA program is this most closely tied to?
Appendix C is tied closely to NASA's Human Research Program (HRP) under the HERO umbrella solicitation managed through NASA Johnson Space Center.
What is a central focus area called out in this appendix?
A central focus is "Analyses of the Temporal Nature of Human Adaptation to Long-Duration Low-Earth Orbit Missions," which centers on how physiological, psychological, and medical changes evolve over time during spaceflight.
What does NASA mean by analyzing the "temporal nature" of adaptation?
NASA is looking for research that characterizes how changes unfold across time in space (not just pre-flight vs. post-flight). The intent is to examine trajectories, potential tipping points, and recovery patterns, and to assess whether risks become unacceptable when mission duration extends beyond typical six-month ISS expeditions.
Why is NASA interested in one-year missions compared to the typical six-month ISS missions?
HRP states it needs enough direct, one-year flight experience to determine whether harmful effects appear (or do not appear) beyond the current experience base of roughly six-month expeditions. This supports credible extrapolation to early interplanetary expeditions that could last about two to three years.
What is the Integrated One-Year Mission Project (i1YMP) design described in the solicitation?
HRP outlines an integrated ISS research design that includes multiple mission durations and comparison groups: five one-year missions, five standard six-month missions that run in parallel, and short-duration crew vehicle exchange expeditions (up to about two months) occurring at the midpoint of each one-year mission.
How many crewmember subjects are included in the planned integrated design?
The planned structure includes: five one-year missions involving a total of 10 crewmember subjects; five standard six-month missions totaling 10 subjects; and five short-duration crew vehicle exchange expeditions totaling 10 subjects.
How long are the short-duration crew vehicle exchange expeditions?
They are described as lasting up to about two months each and occurring at the midpoint of each one-year mission.
What kind of study approach is NASA signaling it wants for long-duration adaptation research?
NASA is signaling interest in proposals that leverage the integrated set of mission durations and comparison groups to study time-dependent adaptation, tipping points, and recovery trajectories, rather than treating long-duration spaceflight as a single before-and-after outcome.
Are there other research topics in Appendix C beyond the one-year mission temporal analyses?
Yes. Appendix C also solicits proposals across additional biological, physiological, and behavioral research topics tied to exploration mission readiness.
Does Appendix C include research involving mice and partial gravity?
Yes. One solicited topic involves studies of the biological, physiological, and behavioral functions of mice exposed to partial gravity levels between 0 and 1 G using centrifugation on the ISS. This area is jointly solicited by HRP and NASA's Space Biology Program.
Is Spaceflight-Associated Neuro-Ocular Syndrome (SANS) included as a topic?
Yes. Appendix C includes developing and testing novel hypotheses and countermeasures for Spaceflight-Associated Neuro-Ocular Syndrome (SANS).
Does the solicitation mention medical countermeasures related to space radiation?
Yes. Appendix C includes advancing medical countermeasures that protect multiple tissues affected by space radiation.
Are human performance and team training topics part of this appendix?
Yes. The appendix includes improving human performance through individual and team problem-solving skills training designed for exploration conditions.
Does Appendix C include sensory stimulation approaches for cognitive and behavioral health?
Yes. The appendix calls for work on sensory stimulation approaches that support cognitive and behavioral health.
What is "Human Capabilities Assessments for Autonomous Missions (HCAAM)" in this opportunity?
HCAAM is included as a research area and is framed as a Virtual NASA Specialized Center of Research. It reflects NASA's interest in assessing and supporting crew capabilities when communication delays increase and missions require greater operational autonomy during deep-space exploration.
What type of funding mechanism does NASA expect to use?
The opportunity allows multiple award mechanisms, including grants, cooperative agreements, and procurement contracts.
Is this opportunity discretionary?
Yes. The opportunity is categorized as discretionary.
What is the CFDA listing for this opportunity?
The CFDA listing provided is 43.003.
What is the maximum (ceiling) award amount stated in the posting?
The posted award ceiling is $1,800,000.
How many awards did NASA anticipate making under this appendix?
NASA anticipated about 18 awards under Appendix C.
Who is eligible to apply?
Eligibility is broadly open across U.S. institutions and is described as unrestricted by organizational type.
Can a principal investigator collaborate with other organizations?
Yes. Principal investigators may collaborate with universities, federal laboratories, private sector partners, and state or local government labs. The applying organization is responsible for overall project management as proposed.
Are collaborations with non-U.S. organizations allowed?
They may occur only on a cooperative, no-exchange-of-funds basis. In other words, NASA funding generally does not flow to foreign partners through this mechanism.
Was there a pre-proposers conference for this solicitation?
Yes. A virtual pre-proposers conference was scheduled for December 11, 2017, with details to be posted on NSPIRES.
What was the proposal process for Appendix C?
The solicitation used a two-step proposal process with Step-1 proposals followed by invited Step-2 proposals.
When were Step-1 proposals due?
Step-1 proposals for Appendix C were due January 4, 2018.
When were Step-2 proposals due?
Step-2 proposals were due April 4, 2018, by invitation.
Where were official submission and updates handled?
Official submission and updates were handled through NSPIRES.
Where could applicants find the full appendix details and related documents?
Additional documents and full appendix details were provided through the HERO BPBA link and the broader NASA HERO research opportunities page, with official solicitation information managed in NSPIRES.
What is the response area number for this appendix?
The response area number is 80JSC017N0001-BPBA.
Which NASA center issued this NRA?
This NRA is from the NASA Johnson Space Center.
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