Opportunity Information: Apply for BAA 10 02 RH

  • The Air Force Research Lab in the science and technology and other research and development sector is offering a public funding opportunity titled "Applied BioSciences Research" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.800 Air Force Defense Research Sciences Program.
  • This funding opportunity was created on Nov 24, 2009 and posted on Nov 24, 2009.
  • Applicants must submit their applications by Jan 15, 2010. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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Opportunity Summary:

This funding opportunity, titled "Applied BioSciences Research" (Funding Opportunity Number: BAA 10 02 RH), is an Air Force Research Laboratory (AFRL) announcement focused on partnering with the Applied Biotechnology Branch within the Biosciences and Performance Division of the Human Effectiveness Directorate, 711th Human Performance Wing. The central aim is to support research and development that advances biotechnology and molecular biology in ways that strengthen warfighter protection, sustain or enhance cognition, and ultimately improve performance and combat effectiveness. While the military application is explicit, the announcement also emphasizes that the resulting innovations should have broader public value through potential civilian applications.

The research scope is organized around six primary technical areas. First, Nano Bio Interaction/Effects covers how nanomaterials interact with biological systems, including the benefits and potential hazards of nanoscale technologies when they contact tissues, cells, and biomolecules. Second, Bioinformatics supports computational and data-driven approaches for handling complex biological data, such as genomic, proteomic, and other high-throughput datasets, with an emphasis on extracting actionable biological insight. Third, Toxicology addresses mechanisms of injury or dysfunction caused by chemical, environmental, or other exposures relevant to operational settings, including detection, characterization, and mitigation of harmful effects. Fourth, Predictive Modeling (PD/PBPK) targets pharmacodynamics and physiologically based pharmacokinetic modeling, which are mathematical frameworks used to predict how substances move through and affect the body; this area is commonly used for anticipating exposure outcomes, optimizing countermeasures, and improving risk assessments. Fifth, Biomarker Discovery/Assay Development focuses on identifying measurable indicators of physiological state, exposure, injury, stress, or performance, and translating those biomarkers into reliable assays or tests that can be used in research or operationally relevant contexts. Sixth, Molecular Foundations supports more fundamental work on the molecular and cellular mechanisms that underlie performance, resilience, adaptation, and response to stressors, providing the scientific basis for future applied capabilities.

Administratively, the opportunity is categorized as discretionary and falls under the Science and Technology and other Research and Development activity area, with CFDA number 12.800 (Air Force Defense Research Sciences Program). The solicitation indicates multiple possible award instruments, including cooperative agreements, grants, procurement contracts, and "other" mechanisms, suggesting flexibility in how AFRL structures partnerships depending on the project and level of government involvement. There is no cost sharing or matching requirement stated, and eligibility is described as unrestricted, meaning it is broadly open to qualified applicants across entity types, subject to any additional eligibility language contained in the full announcement.

Key dates included a posted and created date of November 24, 2009, with an original and current closing date of January 15, 2010, and an archive date of February 14, 2010, indicating this was a time-bound solicitation that has since closed. For access issues or assistance tied to the announcement, the listed point of contact was Mr. Lee Elwood, Contract Negotiator, reachable by phone at (937) 656-9040.

Frequently Asked Questions (FAQs)

1. What is the title of this funding opportunity?

The funding opportunity is titled Applied BioSciences Research.

2. What is the Funding Opportunity Number?

The Funding Opportunity Number is BAA 10 02 RH.

3. Which organization is offering this opportunity?

This announcement is issued by the Air Force Research Laboratory (AFRL), in partnership with the Applied Biotechnology Branch within the Biosciences and Performance Division of the Human Effectiveness Directorate, 711th Human Performance Wing.

4. What is the main purpose of the Applied BioSciences Research opportunity?

The central purpose is to support research and development that advances biotechnology and molecular biology to strengthen warfighter protection, sustain or enhance cognition, and improve performance and overall combat effectiveness.

5. Is the work strictly military, or are civilian applications relevant too?

The solicitation explicitly targets military application, but it also emphasizes that resulting innovations should have broader public value, including potential civilian applications.

6. What are the primary technical areas supported under this announcement?

The research scope is organized into six primary technical areas:

  • Nano Bio Interaction/Effects
  • Bioinformatics
  • Toxicology
  • Predictive Modeling (PD/PBPK)
  • Biomarker Discovery/Assay Development
  • Molecular Foundations

7. What is covered under Nano Bio Interaction/Effects?

This area focuses on how nanomaterials interact with biological systems, including potential benefits and hazards when nanoscale technologies contact tissues, cells, and biomolecules.

8. What kinds of projects fit within the Bioinformatics area?

Bioinformatics supports computational and data-driven approaches for handling complex biological data (including genomic, proteomic, and other high-throughput datasets), with an emphasis on extracting actionable biological insight.

9. What does the Toxicology area focus on?

Toxicology addresses mechanisms of injury or dysfunction caused by chemical, environmental, or other exposures relevant to operational settings, including detection, characterization, and mitigation of harmful effects.

10. What is meant by Predictive Modeling (PD/PBPK)?

This area targets pharmacodynamics (PD) and physiologically based pharmacokinetic (PBPK) modeling. These are mathematical frameworks used to predict how substances move through and affect the body, commonly used to anticipate exposure outcomes, optimize countermeasures, and improve risk assessments.

11. What does Biomarker Discovery/Assay Development include?

This area focuses on identifying measurable indicators of physiological state, exposure, injury, stress, or performance, and translating them into reliable assays or tests that can be used in research or operationally relevant contexts.

12. What is included under Molecular Foundations?

Molecular Foundations supports more fundamental work on molecular and cellular mechanisms underlying performance, resilience, adaptation, and responses to stressors, providing the scientific basis for future applied capabilities.

13. What type of funding opportunity is this administratively?

The opportunity is categorized as discretionary and falls under the Science and Technology and other Research and Development activity area.

14. What is the CFDA number associated with this opportunity?

The CFDA number listed is 12.800, identified as the Air Force Defense Research Sciences Program.

15. What award instruments might be used for projects under this announcement?

The solicitation indicates multiple possible award instruments, including cooperative agreements, grants, procurement contracts, and other mechanisms. This suggests AFRL may choose the instrument based on the project and the expected level of government involvement.

16. Is cost sharing or matching required?

No cost sharing or matching requirement is stated in the information provided.

17. Who is eligible to apply?

Eligibility is described as unrestricted, meaning it is broadly open to qualified applicants across entity types, subject to any additional eligibility language contained in the full announcement.

18. When was the opportunity posted?

The posted (and created) date is November 24, 2009.

19. What were the closing dates for the solicitation?

The original and current closing date listed is January 15, 2010.

20. Has this opportunity been archived?

Yes. The archive date is listed as February 14, 2010, indicating this was a time-bound solicitation that has since closed.

21. Who was the point of contact for questions or access issues?

The listed point of contact was Mr. Lee Elwood, Contract Negotiator.

22. What contact information was provided for the point of contact?

Mr. Lee Elwood was reachable by phone at (937) 656-9040.

23. Does the announcement indicate how AFRL will structure partnerships?

Yes. By listing multiple award instruments (including cooperative agreements, grants, procurement contracts, and other mechanisms), the announcement suggests flexibility in how AFRL structures partnerships depending on project needs and the level of government involvement.

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