Opportunity Information: Apply for APS OAA 10 000003
Apply for APS OAA 10 000003
- The Agency for International Development in the health sector is offering a public funding opportunity titled "APS for Biomedical Research for Reproductive Health" and is now available to receive applicants.
- This funding opportunity was created on Feb 11, 2011 and posted on May 25, 2010.
- Applicants must submit their applications by May 24, 2011. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $28,000,000.00 in funding.
- The number of recipients for this funding is limited to 9 candidate(s).
- Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
- U.S. Organizations or non U.S., non Governement Organizations (NGOs)
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Opportunity Summary:
The APS for Biomedical Research for Reproductive Health is a USAID/Washington funding opportunity designed to support a small number of high-impact projects that advance family planning and reproductive health priorities, with a particular emphasis on product-oriented biomedical innovation. Managed through USAID's Office of Population and Reproductive Health (PRH) in collaboration with the Office of HIV/AIDS (OHA), the solicitation signals the U.S. Government's intent to invest in efforts that move promising reproductive health technologies from the research stage through regulatory pathways and into real-world introduction, especially for women in low-resource settings where unmet need and health risks are often greatest.
At its core, the opportunity focuses on two connected but distinct categories of work. The first is the research and development, regulatory approval, and introduction of new contraceptive methods that address clear gaps in the current contraceptive method mix. This means USAID is not just looking for incremental variations of existing options, but for methods that can meaningfully expand choices for users by filling known shortcomings, whether those relate to usability, duration of action, side effect profiles, delivery mechanisms, or access constraints that limit adoption and continuation. The second category is multipurpose prevention technologies (MPTs) that include contraception while also responding to other reproductive health needs. These MPTs are expected to provide contraceptive protection and additionally deliver one or more of the following: protection against HIV, protection against other sexually transmitted infections and/or reproductive tract infections, suitability for occasional or intermittent use (rather than only continuous or long-acting use), and/or additional health benefits beyond pregnancy prevention. In practice, this prioritizes technologies that can help women manage overlapping risks in a single product, recognizing that pregnancy prevention, HIV/STI prevention, and other reproductive health concerns often occur together in the same contexts.
The announcement makes it clear that USAID expects the work to span a continuum of activities, including early and late-stage research and development, steps needed for regulatory approval, and preparation for and support of product introduction. That "bench to introduction" framing is important because it positions the awards to fund not only scientific development, but also the practical and regulatory work needed to get a technology approved, manufactured, and adopted. The solicitation also emphasizes flexibility and innovation: because product ideas and approaches may vary widely and may not share a single platform or program model, USAID anticipates supporting a diverse set of initiatives rather than forcing all awards into one technical mold.
Another notable feature is the explicit expectation that applicants may need to form partnerships that combine different kinds of expertise. The APS highlights that contraceptive and MPT development can require multiple specialized capabilities, such as biomedical R&D, clinical testing, regulatory strategy and submissions, product development and manufacturing considerations, and planning for introduction in low-resource health systems. The stated intent is to "marshal the greatest amount of technical expertise" around the most promising product leads while staying responsive to evolving needs in the field, which effectively encourages multidisciplinary and multi-organization collaboration.
From a funding and administrative standpoint, the opportunity is a discretionary grant announcement using a Cooperative Agreement, which typically implies a more substantial level of involvement by the funding agency compared to a standard grant. USAID anticipates making a limited number of awards, with an expected total of about nine awards listed. The award ceiling is stated as $28,000,000. Cost sharing or matching is required, meaning applicants should be prepared to contribute resources or secure partner contributions consistent with the solicitation's requirements. The funding activity category is Health.
Eligibility is open to U.S. organizations as well as non-U.S., non-governmental organizations (NGOs), indicating that international nonprofit entities can compete, and that the program is structured to draw from a broad range of global product development and public health expertise. The original posting date is May 25, 2010, with a closing date of May 24, 2011, reflecting a defined application window. For applicants who have trouble accessing the full announcement, the contact listed is Alisa Dunn, Agreement Officer, via the provided email address.
Overall, this APS is best understood as a targeted product-development and introduction funding mechanism aimed at expanding contraceptive choices and accelerating contraceptive MPTs that can also reduce HIV/STI/RTI risks or provide other health benefits, with a strong emphasis on practical pathways to regulatory approval and uptake in low-resource settings, supported by capable partnerships and shared investment through cost matching.
FAQs: APS for Biomedical Research for Reproductive Health (USAID/Washington)
What is this funding opportunity?
This is a USAID/Washington Annual Program Statement (APS) focused on biomedical research for reproductive health. It is designed to support a small number of high-impact projects that advance family planning and reproductive health priorities, with a strong emphasis on product-oriented biomedical innovation.
Which USAID offices are managing or involved in this APS?
The opportunity is managed through USAID's Office of Population and Reproductive Health (PRH) in collaboration with the Office of HIV/AIDS (OHA).
What is the main purpose of the APS?
The APS signals the U.S. Government's intent to invest in efforts that move promising reproductive health technologies from the research stage through regulatory pathways and into real-world introduction, particularly for women in low-resource settings where unmet need and health risks are often greatest.
What kinds of projects does USAID want to support?
The APS focuses on two connected categories of work: (1) development, regulatory approval, and introduction of new contraceptive methods that address gaps in the current contraceptive method mix; and (2) multipurpose prevention technologies (MPTs) that include contraception plus at least one additional reproductive health-related benefit or protection.
What does USAID mean by "new contraceptive methods that address clear gaps"?
USAID is looking for methods that meaningfully expand contraceptive choices by filling known shortcomings in the existing method mix. The emphasis is on addressing issues such as usability, duration of action, side effect profiles, delivery mechanisms, and access constraints that limit adoption and continuation, rather than making only incremental variations of existing options.
What are multipurpose prevention technologies (MPTs) in this APS?
In this APS, MPTs are technologies that provide contraceptive protection and also deliver one or more additional protections or benefits. The APS prioritizes approaches that help women address overlapping risks in a single product.
What additional protections or benefits can an MPT include under this APS?
MPTs are expected to provide contraception and also deliver one or more of the following: protection against HIV; protection against other sexually transmitted infections (STIs) and/or reproductive tract infections (RTIs); suitability for occasional or intermittent use (not only continuous or long-acting use); and/or additional health benefits beyond pregnancy prevention.
Does the APS support both research and real-world rollout activities?
Yes. USAID expects work to span a continuum of activities, including early and late-stage research and development, steps needed for regulatory approval, and preparation for and support of product introduction.
What does "bench to introduction" mean in the context of this APS?
It means awards may fund not only scientific development, but also the practical and regulatory work needed to get a technology approved, manufactured, and adopted in real-world settings.
Is USAID expecting one standard technical platform or approach across awards?
No. The APS emphasizes flexibility and innovation, noting that product ideas and approaches may vary widely and may not share a single platform or program model. USAID anticipates supporting a diverse set of initiatives rather than forcing all awards into one technical mold.
Are partnerships encouraged or required?
The APS explicitly anticipates that applicants may need to form partnerships to combine different kinds of expertise. The intent is to marshal the greatest amount of technical expertise around the most promising product leads while staying responsive to evolving needs.
What kinds of expertise might partnerships need to cover?
The APS notes that contraceptive and MPT development can require multiple specialized capabilities, such as biomedical research and development, clinical testing, regulatory strategy and submissions, product development and manufacturing considerations, and planning for introduction in low-resource health systems.
What type of award mechanism is being used?
This is a discretionary grant announcement using a Cooperative Agreement.
What does it mean that the award is a Cooperative Agreement?
A Cooperative Agreement typically implies a more substantial level of involvement by the funding agency compared to a standard grant.
How many awards does USAID expect to make?
USAID anticipates making a limited number of awards, with an expected total of about nine awards listed.
What is the maximum award amount (award ceiling)?
The award ceiling is stated as $28,000,000.
Is cost sharing or matching required?
Yes. Cost sharing or matching is required, so applicants should be prepared to contribute resources or secure partner contributions consistent with the solicitation's requirements.
What is the funding activity category?
The funding activity category is Health.
Who is eligible to apply?
Eligibility is open to U.S. organizations as well as non-U.S., non-governmental organizations (NGOs). This means international nonprofit entities can compete.
Are government entities outside the U.S. eligible?
The APS states eligibility includes non-U.S., non-governmental organizations (NGOs), which indicates non-U.S. NGOs are eligible. The provided description does not state that non-U.S. governmental entities are eligible.
When was the opportunity posted, and what are the application dates?
The original posting date is May 25, 2010. The closing date is May 24, 2011, reflecting a defined application window.
What populations or settings are emphasized?
The APS places particular emphasis on real-world introduction for women in low-resource settings where unmet need and health risks are often greatest.
What is the main emphasis of the APS: programs or products?
The emphasis is product-oriented biomedical innovation, including moving technologies through regulatory pathways and into introduction and uptake.
Who can applicants contact if they cannot access the full announcement?
The contact listed is Alisa Dunn, Agreement Officer, via the email address provided in the announcement.
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