Opportunity Information: Apply for PA 10 265
Apply for PA 10 265
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Asthma in Older Adults (R03)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.855 Allergy, Immunology and Transplantation Research 93.866 Aging Research.
- This funding opportunity was created on Aug 19, 2010 and posted on Aug 19, 2010.
- Applicants must submit their applications by Sep 7, 2013. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Private institutions of higher education Independent school districts County governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Public and State controlled institutions of higher education Special district governments For profit organizations other than small businesses Public housing authorities/Indian housing authorities Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses Others (see text field entitled Additional Information on Eligibility for clarification) City or township governments Native American tribal governments (Federally recognized) State governments Native American tribal organizations (other than Federally recognized tribal governments).
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:
The Asthma in Older Adults (R03) funding opportunity (PA 10 265) is a National Institutes of Health discretionary grant program designed to support small, focused research projects that improve understanding of asthma specifically in older adult populations. The central idea behind the announcement is that much of the existing adult asthma evidence base comes from studies of younger adults, and that asthma in later life may involve different underlying biological mechanisms, different clinical presentations, and different diagnostic or treatment challenges. Because older adults often have age-related physiological changes and complex health profiles, the FOA emphasizes the need to fill knowledge gaps about how asthma develops, is recognized, and is best managed in later life, with the broader goal of improving prevention strategies and clinical outcomes for older people with asthma.
Scientifically, the FOA invites R03 applications that investigate asthma in older adults across several major areas: pathophysiology (the biological mechanisms and processes driving disease), epidemiology (distribution, risk factors, and population-level patterns), diagnosis (including challenges in correctly identifying asthma and distinguishing it from other conditions), and management (treatment approaches, care strategies, and potentially prevention). NIH explicitly encourages a wide range of research approaches, including basic laboratory studies, translational projects that bridge lab findings to clinical settings, clinical studies involving patients, and epidemiological analyses. The announcement is intentionally broad to stimulate creative proposals that address unanswered questions about asthma in later life and to encourage research that may lead to better diagnostic tools, more tailored therapies, and improved care delivery for older adults.
In terms of project types, this FOA is aligned with the R03 mechanism, which is meant for smaller-scale studies that can be completed relatively quickly and with limited resources. Examples of appropriate projects include pilot and feasibility studies that generate preliminary data for future larger grants, secondary analyses of existing datasets, small self-contained research projects that answer targeted questions, and efforts aimed at developing or refining research methods or creating new research technologies relevant to studying asthma in older adults. In practice, this means applicants can propose smaller, tightly scoped studies that test a specific hypothesis, evaluate the practicality of a clinical or measurement approach, or leverage existing cohorts and databases to examine older-adult asthma questions without the cost and timeline of a large prospective trial.
Structurally, the FOA uses the NIH Small Research Grant (R03) award mechanism and is part of a coordinated set of opportunities with the same scientific scope offered under other NIH mechanisms. Applicants whose work is larger in scale or needs more extensive development are pointed to parallel announcements: PA 10 263 for the R01 mechanism and PA 10 264 for the R21 exploratory/developmental mechanism. This parallel structure signals that NIH is trying to build a pipeline of research on older-adult asthma, from early-stage and feasibility work (R03, R21) through more definitive, larger studies (R01), all focused on the same overarching scientific gaps.
Funding amounts and the number of awards are not set as a fixed figure in the summary information provided, because NIH expects proposals to vary in scope, duration, and cost. Awards will therefore depend on the number of applications submitted, their scientific quality, the requested budgets and project periods, and how well proposed projects fit the goals of the announcement. The FOA also notes that there is no cost sharing or matching requirement, which reduces barriers for applicants who may not have institutional funds to contribute.
Eligibility is broad and includes many types of U.S. organizations and governmental entities, such as public and private institutions of higher education, nonprofit organizations (including those with or without 501(c)(3) status), for-profit organizations (other than small businesses), small businesses, school districts, city/county/state/tribal governments, special district governments, public housing authorities, and other organizations as described in the FOA. The eligibility language also explicitly includes a range of institution types and community-serving organizations, such as Historically Black Colleges and Universities, Hispanic-Serving Institutions, Tribally Controlled Colleges and Universities, Alaska Native and Native Hawaiian Serving Institutions, faith-based or community-based organizations, U.S. territories or possessions, and even non-U.S. entities (foreign organizations) and regional organizations, indicating NIH interest in attracting diverse applicants and settings relevant to aging and asthma.
Administratively, the opportunity was posted on August 19, 2010, with an original and current closing date listed as September 7, 2013, and an archive date of October 8, 2013. It is categorized under health-related funding activities and is associated with CFDA numbers 93.855 (Allergy, Immunology and Transplantation Research) and 93.866 (Aging Research), reflecting the intersection of asthma science with aging-focused research priorities. The full announcement was hosted through the NIH grants guide, and NIH Office of Extramural Research contact information is provided for access or technical issues.
Asthma in Older Adults (R03) (PA-10-265) - FAQs
1) What is the Asthma in Older Adults (R03) funding opportunity?
This opportunity (PA-10-265) is a National Institutes of Health (NIH) discretionary grant program using the Small Research Grant (R03) mechanism. It supports small, focused research projects aimed at improving understanding of asthma specifically in older adult populations.
2) What problem is this FOA trying to address?
The announcement emphasizes that much of the existing evidence base for adult asthma comes from studies of younger adults. NIH highlights the possibility that asthma in later life may involve different biological mechanisms, different clinical presentations, and different diagnostic or treatment challenges. The goal is to fill knowledge gaps so prevention strategies and clinical outcomes can improve for older adults with asthma.
3) What research topics does the FOA encourage?
The FOA invites R03 applications that investigate asthma in older adults across several major areas, including:
- Pathophysiology (biological mechanisms and processes driving disease)
- Epidemiology (distribution, risk factors, and population-level patterns)
- Diagnosis (including challenges in correctly identifying asthma and distinguishing it from other conditions)
- Management (treatment approaches, care strategies, and potentially prevention)
4) What kinds of study approaches are allowed under this FOA?
NIH encourages a wide range of research approaches. Examples mentioned include basic laboratory studies, translational projects that bridge lab findings to clinical settings, clinical studies involving patients, and epidemiological analyses.
5) What types of projects are considered appropriate for an R03 under this FOA?
The R03 mechanism is intended for smaller-scale studies that can be completed relatively quickly and with limited resources. The FOA lists examples such as:
- Pilot and feasibility studies that generate preliminary data for later, larger grants
- Secondary analyses of existing datasets
- Small, self-contained research projects addressing targeted questions
- Development or refinement of research methods
- Creation of new research technologies relevant to studying asthma in older adults
6) Does the FOA restrict applicants to only clinical studies?
No. The FOA explicitly encourages a broad range of approaches, including basic, translational, clinical, and epidemiological work, as long as it focuses on asthma in older adults and addresses the scientific gaps highlighted in the announcement.
7) How does this R03 opportunity relate to other NIH funding mechanisms?
This FOA is part of a coordinated set of opportunities with the same scientific scope offered under other NIH mechanisms. NIH points applicants with larger-scale or more extensive projects to parallel announcements: PA-10-263 (R01) and PA-10-264 (R21). This structure is intended to support a pipeline of research, from early-stage and feasibility work (R03, R21) to larger, more definitive studies (R01).
8) Is the budget or number of awards fixed?
No fixed funding amounts or a fixed number of awards are stated in the information provided. NIH indicates that awards will depend on factors such as the number of applications received, scientific quality, requested budgets and project periods, and alignment with the goals of the announcement.
9) Is cost sharing or matching required?
No. The FOA states there is no cost sharing or matching requirement.
10) Who is eligible to apply?
Eligibility is broad and includes many types of organizations and governmental entities, including:
- Public and private institutions of higher education
- Nonprofit organizations (with or without 501(c)(3) status)
- For-profit organizations (other than small businesses)
- Small businesses
- School districts
- City, county, state, and tribal governments
- Special district governments
- Public housing authorities
- Other organizations as described in the FOA
11) Are minority-serving or community-based institutions explicitly included?
Yes. The eligibility language explicitly includes institution types and community-serving organizations such as Historically Black Colleges and Universities (HBCUs), Hispanic-Serving Institutions, Tribally Controlled Colleges and Universities, Alaska Native and Native Hawaiian Serving Institutions, and faith-based or community-based organizations.
12) Are non-U.S. (foreign) organizations eligible?
Yes. The eligibility description explicitly includes non-U.S. entities (foreign organizations) and regional organizations.
13) What are the key dates listed for this opportunity?
The opportunity was posted on August 19, 2010. The original and current closing date listed is September 7, 2013. The archive date is October 8, 2013.
14) What kind of funding category does this fall under?
It is categorized under health-related funding activities, with a scientific focus at the intersection of asthma science and aging.
15) Which CFDA numbers are associated with this FOA?
The FOA is associated with CFDA 93.855 (Allergy, Immunology and Transplantation Research) and CFDA 93.866 (Aging Research).
16) Where was the full announcement hosted, and what support is mentioned for access issues?
The full announcement was hosted through the NIH grants guide. NIH Office of Extramural Research contact information is provided for access or technical issues.
17) What is the overall goal NIH is trying to achieve with this program?
The broader goal described is to improve prevention strategies and clinical outcomes for older adults with asthma by encouraging studies that clarify how asthma develops, how it is recognized, and how it is best managed in later life.
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