Opportunity Information: Apply for PA 10 264
Apply for PA 10 264
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Asthma in Older Adults (R21)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.838 Lung Diseases Research 93.855 Allergy, Immunology and Transplantation Research 93.866 Aging Research.
- This funding opportunity was created on Aug 19, 2010 and posted on Aug 19, 2010.
- Applicants must submit their applications by Sep 7, 2013. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $200,000.00 in funding.
- Eligible applicants include: Special district governments County governments Small businesses Public housing authorities/Indian housing authorities Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) For profit organizations other than small businesses Independent school districts Public and State controlled institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Private institutions of higher education State governments City or township governments Native American tribal governments (Federally recognized) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:
The Asthma in Older Adults (R21) opportunity (Funding Opportunity Number PA-10-264) is a National Institutes of Health (NIH) funding announcement designed to jump-start exploratory and early-stage research focused specifically on asthma in later life. The central idea behind the announcement is that much of the existing evidence base for adult asthma has come from studies dominated by younger adults, even though asthma in older populations may involve different biological mechanisms, different clinical presentations, and different practical challenges in diagnosis and care. NIH is using this program to push the field toward closing those gaps by supporting innovative, developmental projects that can generate preliminary data, test new concepts, or open up new lines of investigation related to asthma in older adults.
The scope of research encouraged is broad and intentionally flexible. Applications can address the pathophysiology of asthma in older adults (for example, age-related changes in airway inflammation, immune response, or remodeling), epidemiology (such as prevalence, risk factors, comorbidities, or health disparities in older populations), diagnosis (including questions around misdiagnosis or overlap with other cardiopulmonary conditions that are more common with age), and management (covering treatment response, adherence barriers, prevention strategies, and care delivery approaches). NIH explicitly welcomes a range of study types, including basic science, translational work, clinical studies, and population-based or epidemiologic research. The overall goal is to stimulate work that clarifies whether and how asthma in older adults differs from asthma in younger adults, and to use that knowledge to improve diagnostic, treatment, and prevention strategies for older patients.
This funding announcement uses the NIH Exploratory/Developmental Grant (R21) mechanism, which is typically meant for earlier-stage, high-potential ideas that may be too preliminary for a larger, more definitive project. It is also part of a coordinated set of funding opportunities with the same scientific focus: PA-10-263 (R01) for full research projects and PA-10-265 (R03) for small research grants. In other words, NIH provided multiple grant “sizes” for investigators working on the same overarching topic, allowing projects to be matched to the appropriate scale of evidence and readiness.
In terms of funding parameters, the award ceiling listed is $200,000, and there is no cost-sharing or matching requirement. NIH notes that both the size and duration of awards may vary because the proposed projects can differ substantially in scope and design. The total number of awards and total dollars ultimately committed depend on the number of applications received across mechanisms, the scientific merit and quality of those applications, and the requested budgets and timelines.
Eligibility is broad and includes many types of U.S. and non-U.S. organizations. Eligible applicants include public and private institutions of higher education, nonprofit organizations (including those with and without 501(c)(3) status), for-profit organizations (including small businesses and other for-profits), and multiple levels of government (state, county, city/township, special district governments), as well as independent school districts and public/Indian housing authorities. The announcement also highlights additional eligible groups such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian-serving institutions, tribal organizations and tribal governments (including both federally recognized and other than federally recognized categories, as specified), faith-based or community-based organizations, regional organizations, U.S. territories or possessions, and foreign (non-U.S.) entities.
Administratively, the opportunity was posted on August 19, 2010, with an original and current closing date of September 7, 2013, and an archive date of October 8, 2013. The associated CFDA program areas include Lung Diseases Research (93.838), Allergy, Immunology and Transplantation Research (93.855), and Aging Research (93.866), which reflects the cross-cutting nature of asthma in older adults as both a respiratory and aging-related health problem. The full announcement was hosted on the NIH grants guide (link provided in the source text), and NIH provided contact support through the NIH Office of Extramural Research (OER) webmaster for access or technical issues with the posting.
FAQs: Asthma in Older Adults (R21) - NIH (PA-10-264)
What is the Asthma in Older Adults (R21) funding opportunity?
Asthma in Older Adults (R21) (Funding Opportunity Number PA-10-264) is an NIH funding announcement intended to jump-start exploratory and early-stage research focused specifically on asthma in later life, using the NIH Exploratory/Developmental Grant (R21) mechanism.
What is the main purpose of this announcement?
The purpose is to stimulate innovative, developmental projects that can generate preliminary data, test new concepts, or open new lines of investigation about asthma in older adults, especially because much of the adult asthma evidence base has been dominated by studies in younger adults.
Why is NIH emphasizing asthma research in older adults?
NIH is emphasizing this area because asthma in older populations may involve different biological mechanisms, different clinical presentations, and distinct practical challenges in diagnosis and care compared with asthma in younger adults.
What kinds of research topics are encouraged under this opportunity?
The scope is broad and includes (but is not limited to) pathophysiology, epidemiology, diagnosis, and management of asthma in older adults.
What are examples of pathophysiology questions that could fit?
Examples mentioned include age-related changes in airway inflammation, immune response, or airway remodeling in older adults with asthma.
What are examples of epidemiology questions that could fit?
Examples mentioned include studying prevalence, risk factors, comorbidities, or health disparities related to asthma in older populations.
What diagnosis-related issues does the announcement highlight?
The announcement highlights diagnostic questions such as misdiagnosis or overlap between asthma and other cardiopulmonary conditions that are more common with age.
What management-related issues does the announcement encourage researchers to study?
Management topics include treatment response, adherence barriers, prevention strategies, and care delivery approaches for older adults with asthma.
What types of study designs or research approaches are welcomed?
NIH explicitly welcomes a range of study types, including basic science, translational research, clinical studies, and population-based or epidemiologic research.
What is the overall scientific goal across the encouraged research areas?
The overall goal is to clarify whether and how asthma in older adults differs from asthma in younger adults, and to use that knowledge to improve diagnostic, treatment, and prevention strategies for older patients.
What grant mechanism is used for PA-10-264?
This announcement uses the NIH Exploratory/Developmental Grant (R21) mechanism, which is typically used for earlier-stage, high-potential ideas that may be too preliminary for larger, more definitive projects.
Are there related funding opportunities on the same topic?
Yes. NIH offered a coordinated set of opportunities with the same scientific focus: PA-10-263 (R01) for full research projects and PA-10-265 (R03) for small research grants, in addition to PA-10-264 (R21).
How much funding is available per award?
The listed award ceiling is $200,000. NIH also notes that award size and duration may vary because proposed projects can differ substantially in scope and design.
Is cost-sharing or matching required?
No. The announcement states there is no cost-sharing or matching requirement.
How many awards will NIH make under this opportunity?
The total number of awards and the total dollars committed depend on factors such as the number of applications received across mechanisms, the scientific merit and quality of the applications, and the requested budgets and timelines.
Who is eligible to apply?
Eligibility is broad and includes many types of U.S. and non-U.S. organizations, spanning higher education, nonprofit, for-profit, government entities, and other eligible institutions and organizations listed in the announcement.
Are universities and colleges eligible applicants?
Yes. Eligible applicants include public and private institutions of higher education. The announcement also specifically calls out eligibility for groups such as HBCUs, Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), and Alaska Native and Native Hawaiian-serving institutions.
Are nonprofit organizations eligible to apply?
Yes. Nonprofit organizations are eligible, including those with and without 501(c)(3) status.
Are for-profit organizations eligible to apply?
Yes. For-profit organizations are eligible, including small businesses and other for-profit entities.
Are government entities eligible to apply?
Yes. Eligible applicants include state, county, city/township, and special district governments, as well as independent school districts and public/Indian housing authorities.
Are tribal organizations and tribal governments eligible?
Yes. The announcement includes tribal organizations and tribal governments, including both federally recognized and other than federally recognized categories (as specified in the eligibility description).
Are faith-based or community-based organizations eligible?
Yes. The announcement highlights that faith-based and community-based organizations are among the eligible groups.
Are U.S. territories or possessions eligible?
Yes. The eligibility description includes U.S. territories or possessions.
Are foreign (non-U.S.) organizations eligible to apply?
Yes. The eligibility description includes foreign (non-U.S.) entities.
When was this funding opportunity posted?
The opportunity was posted on August 19, 2010.
What was the closing date for applications?
The original and current closing date listed is September 7, 2013.
When was the opportunity archived?
The archive date listed is October 8, 2013.
What CFDA program areas are associated with this funding opportunity?
The associated CFDA program areas include Lung Diseases Research (93.838), Allergy, Immunology and Transplantation Research (93.855), and Aging Research (93.866).
Where was the full announcement hosted?
The full announcement was hosted on the NIH grants guide (a link was provided in the source information).
Who was listed as a contact for access or technical issues with the posting?
NIH provided contact support through the NIH Office of Extramural Research (OER) webmaster for access or technical issues related to the posting.
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