Opportunity Information: Apply for PA 10 263
Apply for PA 10 263
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Asthma in Older Adults (R01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.838 Lung Diseases Research 93.855 Allergy, Immunology and Transplantation Research 93.866 Aging Research.
- This funding opportunity was created on Aug 19, 2010 and posted on Aug 19, 2010.
- Applicants must submit their applications by Sep 7, 2013. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Independent school districts For profit organizations other than small businesses Native American tribal organizations (other than Federally recognized tribal governments) Special district governments Native American tribal governments (Federally recognized) Private institutions of higher education Public and State controlled institutions of higher education City or township governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education State governments County governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) Small businesses Public housing authorities/Indian housing authorities.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:
The Asthma in Older Adults (R01) funding opportunity (PA-10-263) is a National Institutes of Health (NIH) research grant announcement focused on improving what is known about asthma specifically in later life. It is sponsored jointly by three NIH institutes: the National Institute on Aging (NIA), the National Heart, Lung, and Blood Institute (NHLBI), and the National Institute of Allergy and Infectious Diseases (NIAID). The main goal is to encourage full-scale Research Project Grant (R01) applications that examine asthma in older adults across key areas such as underlying disease mechanisms (pathophysiology), population patterns and risk factors (epidemiology), how asthma is identified and differentiated from other conditions (diagnosis), and how it is treated or controlled (management). The rationale behind the program is that much of the evidence base for “adult asthma” comes from studies dominated by younger adult groups, while asthma in older adults may involve different biological drivers and clinical presentations. Those differences can matter a lot for real-world decisions about screening, diagnostic criteria, treatment selection, and prevention strategies for older patients, especially when aging-related changes and common comorbidities complicate the picture.
This FOA is meant to stimulate research that directly fills those gaps in knowledge about asthma in later life. NIH signals that it is open to a wide range of scientific approaches, including basic laboratory science, translational research that links mechanisms to clinical relevance, clinical studies in patient populations, and epidemiological work that can clarify prevalence, incidence, disparities, risk factors, outcomes, and healthcare utilization patterns. In other words, proposals can range from mechanistic studies that explore how aging alters airway inflammation or immune responses, to clinical and population studies that test better diagnostic pathways or management strategies in older cohorts. The unifying requirement is that the focus remains on asthma in older adults and on advancing evidence that could ultimately improve care and outcomes for that age group.
The mechanism of support is the NIH R01, which is the standard, larger-scale project grant intended for well-developed research plans. The announcement also notes that it runs in parallel with two related opportunities of the same scientific scope: PA-10-265 for the R03 (small research grant) mechanism and PA-10-264 for the R21 (exploratory/developmental) mechanism. Practically, that means investigators with smaller pilot projects or earlier-stage ideas could consider those companion mechanisms, while this particular FOA is for applicants ready to propose a more comprehensive R01-level project.
In terms of budget and award count, NIH does not set a fixed amount for this announcement because the size and complexity of proposed projects can vary widely. Instead, the expected size and duration of each award are flexible and will depend on what is scientifically appropriate for each application. The total dollars awarded and the number of awards ultimately made depend on how many applications are submitted, how strong they are, how long they run, and what they cost, along with NIH’s available funds and program priorities at the time of award decisions. Cost sharing or matching is not required.
Eligibility is broad and includes many types of domestic and non-domestic organizations. Eligible applicants listed include public and private institutions of higher education, nonprofits (including 501(c)(3) and non-501(c)(3) organizations), for-profit organizations (other than small businesses), small businesses, and a variety of government entities (state, county, city/township, special district governments, and independent school districts). Tribal organizations and tribal governments are eligible, including federally recognized tribal governments and other tribal entities. The FOA also explicitly includes a range of mission- and community-oriented institution types such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Alaska Native and Native Hawaiian-serving institutions, tribally controlled colleges and universities (TCCUs), faith-based or community-based organizations, U.S. territories or possessions, regional organizations, and eligible federal agencies. Foreign (non-U.S.) entities are also listed as eligible, which can be important for international collaborations or studies that require specific populations or comparative settings.
Key administrative details in the source information include the posting and creation date of August 19, 2010, with an original and current closing date of September 7, 2013, and an archive date of October 8, 2013 (meaning it is no longer an active, open call). The activity category is Health, and the associated CFDA numbers are 93.838 (Lung Diseases Research), 93.855 (Allergy, Immunology and Transplantation Research), and 93.866 (Aging Research), reflecting the cross-cutting nature of asthma in older adults across pulmonary science, immunology, and aging. For applicants needing the full text, the announcement points to the NIH grants guide page (noting the link provided), and it provides NIH Office of Extramural Research (OER) webmaster emails for technical access or linking issues.
Frequently Asked Questions (FAQs): Asthma in Older Adults (R01) - PA-10-263
What is the Asthma in Older Adults (R01) funding opportunity?
The Asthma in Older Adults (R01) funding opportunity (PA-10-263) is an NIH research grant announcement that encourages full-scale Research Project Grant (R01) applications aimed at improving what is known about asthma specifically in later life.
Which NIH institutes sponsor PA-10-263?
This announcement is jointly sponsored by three NIH institutes: the National Institute on Aging (NIA), the National Heart, Lung, and Blood Institute (NHLBI), and the National Institute of Allergy and Infectious Diseases (NIAID).
What is the main purpose or goal of this FOA?
The main goal is to stimulate R01-level research focused on asthma in older adults, especially research that fills gaps in evidence that may exist because much of the current "adult asthma" literature is based on younger adult populations.
What research areas does the FOA emphasize?
The FOA highlights research on asthma in older adults across major areas, including underlying disease mechanisms (pathophysiology), population patterns and risk factors (epidemiology), how asthma is identified and differentiated from other conditions (diagnosis), and how asthma is treated or controlled (management).
Why does NIH emphasize asthma in older adults specifically?
The rationale is that asthma in later life may involve different biological drivers and clinical presentations than asthma studied primarily in younger adult groups. Those differences can affect real-world decisions related to screening, diagnostic criteria, treatment selection, and prevention strategies, particularly when aging-related changes and common comorbidities complicate diagnosis and management.
What types of scientific approaches are considered responsive to this FOA?
NIH indicates openness to a wide range of approaches, including basic laboratory science, translational research connecting mechanisms to clinical relevance, clinical studies in patient populations, and epidemiological studies that clarify prevalence, incidence, disparities, risk factors, outcomes, and healthcare utilization patterns.
Are both clinical and non-clinical studies allowed?
Yes. Based on the announcement description, applications may include basic mechanistic studies (for example, examining how aging alters airway inflammation or immune responses) as well as clinical and population studies (for example, testing improved diagnostic pathways or management strategies in older cohorts), as long as the focus remains on asthma in older adults.
What is the funding mechanism for PA-10-263?
The mechanism of support is the NIH R01, which is intended for larger, well-developed research plans and full-scale projects.
Are there related NIH opportunities for smaller or earlier-stage projects?
Yes. The announcement notes two companion opportunities of the same scientific scope: PA-10-265 for the R03 (small research grant) mechanism and PA-10-264 for the R21 (exploratory/developmental) mechanism.
Does NIH set a fixed budget amount for awards under this FOA?
No. NIH does not set a fixed amount for this announcement because proposed projects can vary in size and complexity. The expected size and duration of each award are flexible and depend on what is scientifically appropriate for the application.
How are the number of awards and total dollars determined?
The total number of awards and total funding depend on factors described in the announcement, including how many applications are submitted, their scientific strength, project durations, requested costs, NIH’s available funds, and program priorities at the time award decisions are made.
Is cost sharing or matching required?
No. Cost sharing or matching is not required for this funding opportunity.
Who is eligible to apply?
Eligibility is broad and includes many domestic and non-domestic organizations. Eligible applicants include public and private institutions of higher education; nonprofits (including 501(c)(3) and non-501(c)(3) organizations); for-profit organizations (other than small businesses); small businesses; and multiple types of government entities.
What types of government entities are eligible?
The FOA lists a variety of eligible government entities, including state governments, county governments, city or township governments, special district governments, and independent school districts.
Are tribal governments and tribal organizations eligible?
Yes. The FOA includes tribal organizations and tribal governments as eligible applicants, including federally recognized tribal governments and other tribal entities.
Are community-based or faith-based organizations eligible?
Yes. The FOA explicitly includes faith-based or community-based organizations among eligible applicants.
Are minority-serving institutions specifically included as eligible applicants?
Yes. The FOA explicitly includes institution types such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Alaska Native and Native Hawaiian-serving institutions, and tribally controlled colleges and universities (TCCUs).
Are U.S. territories or possessions eligible?
Yes. The FOA includes U.S. territories or possessions among eligible applicants, and also lists regional organizations and eligible federal agencies.
Are foreign (non-U.S.) entities allowed to apply?
Yes. The FOA states that foreign (non-U.S.) entities are eligible, which may support international collaborations or studies involving specific populations or comparative settings.
Is this funding opportunity still open?
No. The administrative details provided indicate this opportunity is archived and no longer active. It has an original and current closing date of September 7, 2013, and an archive date of October 8, 2013.
When was the opportunity posted?
The posting and creation date listed for this opportunity is August 19, 2010.
What is the activity or subject category associated with this FOA?
The activity category is Health, reflecting the biomedical and public health focus of asthma research in older adults.
What CFDA numbers are associated with this announcement?
The associated CFDA numbers listed are 93.838 (Lung Diseases Research), 93.855 (Allergy, Immunology and Transplantation Research), and 93.866 (Aging Research).
Where can applicants find the full text of the announcement?
The information provided notes that the full text is available through the NIH grants guide page referenced by the announcement.
Who should be contacted for technical issues accessing or linking to the announcement?
For technical access or linking issues, the announcement provides NIH Office of Extramural Research (OER) webmaster email contacts.
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Applicants also applied for:
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