Support of NIGMS Program Project Grants (P01) | Apply Online

Opportunity Summary:

Support of NIGMS Program Project Grants (P01) is a National Institutes of Health funding opportunity from the National Institute of General Medical Sciences (NIGMS) that is meant to spur ambitious, team-based biomedical research organized around a single major biological question. The central idea is to support research programs where several projects are tightly connected and genuinely interdependent, so that pursuing them together creates clear scientific advantages compared with funding the same work as separate, stand-alone investigator grants. NIGMS is specifically looking for applications that are innovative and interactive, bringing together outstanding scientists in ways that may not happen naturally without a structured, multi-project grant. In other words, the program is designed for collaborations that are more than the sum of their parts, with the expectation that the combined approach will accelerate progress on an important NIGMS-relevant problem.

The mechanism used is the P01 Program Project Grant, a well-established NIH grant structure that supports a coordinated set of research projects that share a common theme. Under a P01, the proposed projects are expected to be connected by a unifying scientific objective, and the overall program should demonstrate strong collaboration and integration across the participating research groups. The rationale emphasized in the announcement is that a grouped, coordinated award should enable efficiencies, cross-fertilization of ideas, and scientific outcomes that would be difficult to achieve if each project were funded independently through regular research grants.

Funding levels and the number of awards are not set in advance as a fixed total. Instead, NIGMS indicates that awards will be made based on the scientific merit of submitted applications and the amount of money available in the Institute's general funding pool. Because proposed programs can differ widely in scope, complexity, and resource needs, the size and duration of each award can also vary. The agency notes that the final total dollars awarded and the number of funded applications will depend on how many applications are submitted, their quality, the length of the proposed projects, and their requested budgets.

The opportunity is categorized as a discretionary grant in the health area, listed under CFDA 93.859 (Biomedical Research and Research Training), and it does not require cost sharing or matching funds. A broad range of organizations are eligible to apply, including public and private institutions of higher education, nonprofit organizations (including 501(c)(3) and certain non-501(c)(3) nonprofits), for-profit organizations (other than small businesses), small businesses, and multiple levels of government such as state, county, city/township, special district governments, public housing authorities/Indian housing authorities, and certain tribal entities. The eligibility language also explicitly includes a number of institution types and community-based categories, such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, faith-based or community-based organizations, regional organizations, eligible federal agencies, and applicants from U.S. territories or possessions, as well as Native American tribal governments (federally recognized and other than federally recognized, as specified).

Key administrative details in the listing include the Funding Opportunity Number PAR 10 266 and the title Support of NIGMS Program Project Grants (P01). The opportunity was posted on Aug 19, 2010, with system dates showing a creation date of Jun 3, 2011, and an archive date of Jun 30, 2011. The listing shows an original closing date of Sep 7, 2013, and a current closing date of May 31, 2011, reflecting how the opportunity was tracked at the time in the source system. Applicants are directed to the NIH Grants Guide posting for the full announcement text (PAR 10 266), and troubleshooting for access or linking issues is routed to the NIH Office of Extramural Research (OER) webmaster contact.

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