Behavioral and Integrative Treatment Development Program (R01) | Apply Online

Frequently Asked Questions (FAQs)

What is the Behavioral and Integrative Treatment Development Program (R01) (PA-10-012)?

PA-10-012 is a National Institutes of Health (NIH) discretionary funding opportunity that uses the NIH Research Project Grant (R01) mechanism to support full-scale research projects. The program focuses on developing and testing treatment interventions for drug abuse and addiction, especially interventions that are behavioral or integrative (for example, combined, sequential, or fully integrated approaches that may include pharmacological components).

What kinds of interventions does this program aim to support?

The program emphasizes research that develops and evaluates treatment interventions for drug abuse and addiction, including behavioral approaches and interventions that combine behavioral and pharmacological components (combined, sequential, or fully integrated models). The stated intent is to strengthen evidence for what works in real-world treatment and prevention contexts.

What are the main scientific priority areas described in the opportunity?

The priorities described include: (1) drug abuse treatment interventions delivered in diverse settings, including for patients with comorbidities; (2) interventions that reduce HIV acquisition or transmission among people in drug abuse treatment; (3) strategies to improve adherence to drug abuse treatment and to HIV and addiction medications; and (4) interventions to treat chronic pain where behavioral and integrated care models may be important.

Does the program support research focused on comorbidities in people with substance use disorders?

Yes. The opportunity highlights research tailored for patients with comorbidities and gives examples such as co-occurring mental health disorders, infectious diseases, or other chronic conditions.

Is HIV-related research within scope for PA-10-012?

Yes. One stated emphasis is on interventions that reduce HIV acquisition or transmission among individuals who are in drug abuse treatment, reflecting the relationship between substance use and HIV risk.

Does the opportunity include research on improving treatment adherence?

Yes. The program encourages intervention strategies aimed at improving adherence both to drug abuse treatment and to HIV and addiction medications, noting adherence as a major barrier to treatment effectiveness in practice.

Is chronic pain research included in the scope of this FOA?

Yes. The priorities include interventions to treat chronic pain, described as closely tied to substance use risk and opioid misuse, and an area where behavioral and integrated care approaches can be especially important.

How does PA-10-012 relate to the R03 and R34 announcements mentioned?

The information provided indicates PA-10-012 is the R01 version within a family of related NIH announcements that share the same scientific scope but use different grant mechanisms. A parallel small grant R03 announcement runs alongside this R01 opportunity, and an R34 planning grant mechanism is also referenced (PA-10-013). The structure is described as allowing applicants to choose a mechanism that matches the maturity and scale of the proposed work (R03 for smaller/discrete efforts, R34 for planning and preparation for clinical trials, and R01 for larger, full-scale projects).

What grant mechanism does PA-10-012 use?

PA-10-012 uses the NIH Research Project Grant (R01) mechanism, described as supporting full-scale research projects compared to smaller, shorter-duration mechanisms like R03.

Who is eligible to apply for PA-10-012?

Eligibility is described as broad, including many domestic and non-domestic organization types. Eligible applicants listed include public and private institutions of higher education, nonprofits with or without 501(c)(3) status, for-profit organizations (including small businesses and other for-profits), and state and local governments (including counties, cities or townships, and special district governments).

Are school districts and housing authorities eligible to apply?

Yes. The eligibility list explicitly includes independent school districts and public housing authorities/Indian housing authorities.

Are minority-serving institutions specifically included in the eligibility language?

Yes. The eligibility language explicitly includes institutions such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Alaska Native and Native Hawaiian Serving Institutions, and Tribally Controlled Colleges and Universities (TCCUs).

Are tribal governments eligible applicants?

Yes. The eligibility language includes tribal governments (both federally recognized tribal governments and tribal governments other than federally recognized).

Are faith-based and community-based organizations eligible?

Yes. The eligibility language explicitly includes faith-based or community-based organizations.

Are U.S. territories or possessions and regional organizations eligible?

Yes. The eligibility language includes U.S. territories or possessions and regional organizations.

Can federal agencies apply?

Yes. The eligibility language includes eligible federal agencies.

Are foreign (non-U.S.) organizations eligible to apply?

Yes. The eligibility language explicitly includes foreign organizations or other non-U.S. entities.

Is cost sharing or matching required under this opportunity?

No. The opportunity indicates there is no cost sharing or matching requirement, meaning applicants are generally not required to contribute non-federal funds as a condition of award.

What funding activity area is associated with this opportunity?

The opportunity is categorized as a grant within the education and health funding activity area.

What CFDA numbers are associated with PA-10-012?

The opportunity is associated with CFDA 93.279 (Drug Abuse and Addiction Research Programs) and CFDA 93.361 (Nursing Research), indicating alignment with addiction research as well as nursing and broader health services research perspectives.

Are awards guaranteed if an application is submitted?

No. The information states awards are contingent on available funds and on receiving a sufficient number of high-quality, meritorious applications, which means the number of awards can vary based on funding levels and application quality.

When was this FOA posted, and is it still active?

The information provided states the opportunity was posted in October 2009 and lists an original closing date of January 7, 2013, with an archive date in February 2013. Based on those dates, it is best understood as a historical FOA that was active during that period.

Where can applicants find the official NIH FOA notice for PA-10-012?

The information references the NIH guide notice page at: http://grants.nih.gov/grants/guide/pa-files/PA-10-012.html

Who is the contact for access or technical issues with the FOA page?

The information provided notes that NIH included Office of Extramural Research (OER) webmaster contact information for access or technical issues related to the official page.