Opportunity Information: Apply for PA 10 010
Apply for PA 10 010
- The National Institutes of Health in the education environment health income security and social services sector is offering a public funding opportunity titled "Exploratory/Developmental Bioengineering Research Grants (EBRG) R21" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113 Environmental Health 93.121 Oral Diseases and Disorders Research 93.172 Human Genome Research 93.173 Research Related to Deafness and Communication Disorders 93.242 Mental Health Research Grants 93.273 Alcohol Research Programs 93.279 Drug Abuse and Addiction Research Programs 93.286 Discovery and Applied Research for Technological Innovations to Improve Human Health 93.393 Cancer Cause and Prevention Research 93.394 Cancer Detection and Diagnosis Research 93.395 Cancer Treatment Research 93.396 Cancer Biology Research 93.399 Cancer Control 93.837 Cardiovascular Diseases Research 93.838 Lung Diseases Research 93.839 Blood Diseases and Resources Research 93.846 Arthritis, Musculoskeletal and Skin Diseases Research 93.853 Extramural Research Programs in the Neurosciences and Neurological Disorders 93.865 Child Health and Human Development Extramural Research 93.866 Aging Research 93.867 Vision Research.
- This funding opportunity was created on Oct 14, 2009 and posted on Oct 14, 2009.
- Applicants must submit their applications by Jan 7, 2013. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $200,000.00 in funding.
- Eligible applicants include: Private institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal governments (Federally recognized) Small businesses Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) State governments Public and State controlled institutions of higher education For profit organizations other than small businesses.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:
The Exploratory/Developmental Bioengineering Research Grants (EBRG) R21 opportunity (Funding Opportunity Number PA-10-010) is a National Institutes of Health (NIH) grant program designed to spark innovative, high-risk/high-impact bioengineering research, especially in areas that are new or not yet well developed. The central idea is to give investigators room to test bold concepts, early-stage technologies, or unconventional approaches that could open up entirely new lines of research or lead to meaningful advances in human health. Unlike many NIH mechanisms that expect substantial preliminary results, this FOA explicitly signals that minimal or even no preliminary data may be acceptable, as long as the application makes a strong case that the work matters, is scientifically sound, and is realistically achievable with the team and resources in place.
From a project scope standpoint, the FOA is intentionally broad and flexible. Applications can be hypothesis-driven or discovery-driven, and they may focus on development, design, or proof-of-concept work. The proposed research can involve exploring new concepts within a specific substantive area, creating or refining new technologies, techniques, or methods, or generating initial datasets that provide the foundation for larger, more definitive future studies. In practice, this makes the program a fit for early exploratory work in bioengineering that might be considered too preliminary or too speculative for more traditional funding routes, but still has a clear potential to move the field forward.
The funding mechanism used is the NIH Exploratory/Developmental Grant Award (R21). This announcement is described as running in parallel with other NIH opportunities that cover similar scientific territory, including PA-10-009 (Bioengineering Research Grants) and PAR-07-352 (Bioengineering Research Partnerships). The parallel structure is meant to give applicants multiple entry points depending on the maturity of the idea, the scale of collaboration, and the type of work proposed, with the R21 specifically emphasizing exploratory and developmental efforts.
In terms of funding size, the listed award ceiling is $200,000, and the FOA notes that the size and duration of awards may vary because proposed projects can differ widely in goals and scope. In other words, NIH is not framing this as a one-size-fits-all program; it is geared toward supporting a range of early-stage bioengineering efforts, with budgets tailored to what a specific exploratory project reasonably requires.
Eligibility is broad and includes many types of organizations. Eligible applicants include public and state-controlled institutions of higher education, private institutions of higher education, nonprofits (both 501(c)(3) and certain non-501(c)(3) entities), small businesses, and for-profit organizations other than small businesses. Governmental and community-based entities are also included, such as state governments, U.S. territories or possessions, and tribal governments (federally recognized and other categories described in the FOA). The eligibility language also explicitly includes several institution types that NIH often highlights for inclusion and capacity-building, such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and even non-U.S. entities (foreign organizations), depending on the specific NIH eligibility rules referenced in the full announcement. The FOA states there is no cost sharing or matching requirement, which lowers the barrier to participation for organizations that may not have discretionary funds to contribute.
The program is categorized as a discretionary grant opportunity and is associated with a wide range of CFDA numbers spanning many NIH mission areas. These include environmental health, oral health, human genome research, communication disorders, mental health, alcohol and drug abuse research, cancer research (across prevention, diagnosis, treatment, biology, and control), cardiovascular and pulmonary research, blood disorders, musculoskeletal and skin diseases, neurological disorders, child health and human development, aging, and vision research. The breadth of these CFDA listings underscores that the bioengineering focus is intended to be applied across many disease areas and biomedical challenges, rather than confined to a single institute or condition.
Administratively, the opportunity was posted on October 14, 2009, with an original and current closing date listed as January 7, 2013, and an archive date of February 7, 2013. The full announcement was available through NIH’s grants guide (linked in the opportunity details), and NIH provided contact support through the NIH Office of Extramural Research (OER) webmaster for applicants who had trouble accessing or linking to the announcement.
Frequently Asked Questions (FAQs)
What is the Exploratory/Developmental Bioengineering Research Grants (EBRG) R21 opportunity?
The Exploratory/Developmental Bioengineering Research Grants (EBRG) R21 is an NIH grant opportunity designed to encourage innovative, high-risk/high-impact bioengineering research, particularly in areas that are new or not yet well developed. It supports early-stage work meant to test bold concepts, early technologies, or unconventional approaches that could open new research directions or advance human health.
What is the Funding Opportunity Number (FOA number) for this program?
The Funding Opportunity Number listed is PA-10-010.
What NIH grant mechanism does this opportunity use?
This opportunity uses the NIH Exploratory/Developmental Grant Award (R21) mechanism.
What kind of research is this program trying to support?
The program is intended to spark innovative and exploratory bioengineering research. It is especially aimed at early-stage, high-risk/high-reward projects that may be too preliminary or speculative for more traditional funding mechanisms but still have clear potential to move the field forward.
Is preliminary data required to apply?
The announcement explicitly signals that minimal or even no preliminary data may be acceptable, as long as the application makes a strong case that the work is important, scientifically sound, and realistically achievable with the team and resources available.
Does the FOA allow both hypothesis-driven and discovery-driven projects?
Yes. The FOA states that applications can be hypothesis-driven or discovery-driven.
What types of project activities fit within the scope of this R21?
The scope is broad and flexible. Examples described include development, design, and proof-of-concept work; exploring new concepts within a substantive area; creating or refining technologies, techniques, or methods; and generating initial datasets that can serve as a foundation for larger future studies.
How much funding is available per award?
The listed award ceiling is $200,000. The FOA also notes that the size and duration of awards may vary depending on project goals and scope.
Is the award size and project duration fixed?
No. The FOA indicates that award size and duration may vary because proposed projects can differ widely in goals and scope.
Is cost sharing or matching required?
No. The FOA states there is no cost sharing or matching requirement.
What types of organizations are eligible to apply?
Eligibility is broad and includes public and state-controlled institutions of higher education, private institutions of higher education, nonprofits (including 501(c)(3) and certain non-501(c)(3) entities), small businesses, and for-profit organizations other than small businesses. Governmental and community-based entities are also included, such as state governments, U.S. territories or possessions, and tribal governments (including federally recognized and other categories described in the FOA).
Are minority-serving institutions specifically included in the eligibility language?
Yes. The eligibility language explicitly includes institution types often highlighted for inclusion and capacity-building, such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), and Alaska Native and Native Hawaiian Serving Institutions.
Are foreign (non-U.S.) organizations eligible to apply?
The FOA explicitly mentions that non-U.S. entities (foreign organizations) are included, depending on the specific NIH eligibility rules referenced in the full announcement.
Is this considered a discretionary grant opportunity?
Yes. The opportunity is categorized as a discretionary grant opportunity.
What scientific or health areas does this program cover?
The opportunity is associated with a wide range of CFDA numbers spanning many NIH mission areas. Examples listed include environmental health, oral health, human genome research, communication disorders, mental health, alcohol and drug abuse research, cancer research (prevention, diagnosis, treatment, biology, and control), cardiovascular and pulmonary research, blood disorders, musculoskeletal and skin diseases, neurological disorders, child health and human development, aging, and vision research. This breadth reflects that bioengineering is intended to be applied across many disease areas and biomedical challenges.
Is the FOA limited to a single NIH institute or disease area?
No. The wide range of associated CFDA numbers underscores that the bioengineering focus is meant to apply across many NIH mission areas rather than being confined to one institute or condition.
How does this R21 FOA relate to other NIH bioengineering opportunities?
The announcement is described as running in parallel with other NIH opportunities covering similar scientific territory, including PA-10-009 (Bioengineering Research Grants) and PAR-07-352 (Bioengineering Research Partnerships). The parallel structure is intended to provide multiple entry points based on the maturity of the idea, the scale of collaboration, and the type of work proposed, with this R21 emphasizing exploratory and developmental efforts.
When was this opportunity posted?
The opportunity was posted on October 14, 2009.
What were the closing date and archive date for this opportunity?
The original and current closing date listed is January 7, 2013, and the archive date is February 7, 2013.
Where was the full announcement made available?
The full announcement was available through NIH's grants guide (linked in the opportunity details).
Who was listed as a contact for access or linking issues?
NIH provided contact support through the NIH Office of Extramural Research (OER) webmaster for applicants who had trouble accessing or linking to the announcement.
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Applicants also applied for:
Applicants who have applied for this opportunity (PA 10 010) also looked into and applied for these:
| Funding Opportunity |
|---|
| Ruth L. Kirschstein National Research Service Award (NRSA) Institutional Research Training Grants (T32) Apply for PA 10 036 Funding Number: PA 10 036 Agency: National Institutes of Health Category: Education Environment Health Income Security and Social Services Funding Amount: Case Dependent |
| Ruth L. Kirschstein National Research Service Award Short Term Institutional Research Training Grants (T35) Apply for PA 10 037 Funding Number: PA 10 037 Agency: National Institutes of Health Category: Education Environment Health Income Security and Social Services Funding Amount: Case Dependent |
| Blueprint Program for Enhancing Neuroscience Diversity through Undergraduate Research Education Experiences (R25) Apply for RFA MH 10 070 Funding Number: RFA MH 10 070 Agency: National Institutes of Health Category: Education Environment Health Income Security and Social Services Funding Amount: Case Dependent |
| Independent Scientist Award (Parent K02) Apply for PA 10 057 Funding Number: PA 10 057 Agency: National Institutes of Health Category: Education Environment Health Income Security and Social Services Funding Amount: Case Dependent |
| NIH Exploratory Developmental Research Grant Program (Parent R21) Apply for PA 10 069 Funding Number: PA 10 069 Agency: National Institutes of Health Category: Education Environment Health Income Security and Social Services Funding Amount: $200,000 |
| Ruth L. Kirschstein National Research Service Awards (NRSA) for Individual Senior Fellows (Parent F33) Apply for PA 10 111 Funding Number: PA 10 111 Agency: National Institutes of Health Category: Education Environment Health Income Security and Social Services Funding Amount: Case Dependent |
| Understanding and Promoting Health Literacy (R03) Apply for PAR 10 134 Funding Number: PAR 10 134 Agency: National Institutes of Health Category: Education Environment Health Income Security and Social Services Funding Amount: Case Dependent |
| Understanding and Promoting Health Literacy (R21) Apply for PAR 10 135 Funding Number: PAR 10 135 Agency: National Institutes of Health Category: Education Environment Health Income Security and Social Services Funding Amount: $200,000 |
| Behavioral and Social Science Research on Understanding and Reducing Health Disparities (R21) Apply for PAR 10 137 Funding Number: PAR 10 137 Agency: National Institutes of Health Category: Education Environment Health Income Security and Social Services Funding Amount: $200,000 |
| Innovative Neuroscience K 12 Education (SBIR R43/R44) Apply for PAR 10 154 Funding Number: PAR 10 154 Agency: National Institutes of Health Category: Education Environment Health Income Security and Social Services Funding Amount: Case Dependent |
| Research on Autism and Autism Spectrum Disorders (R01) Apply for PA 10 158 Funding Number: PA 10 158 Agency: National Institutes of Health Category: Education Environment Health Income Security and Social Services Funding Amount: Case Dependent |
| Research On Autism And Autism Spectrum Disorders (R03) Apply for PA 10 159 Funding Number: PA 10 159 Agency: National Institutes of Health Category: Education Environment Health Income Security and Social Services Funding Amount: Case Dependent |
| Research on Autism and Autism Spectrum Disorders (R21) Apply for PA 10 160 Funding Number: PA 10 160 Agency: National Institutes of Health Category: Education Environment Health Income Security and Social Services Funding Amount: $200,000 |
| International Neuroscience Fellowship (F05) Apply for PAR 10 167 Funding Number: PAR 10 167 Agency: National Institutes of Health Category: Education Environment Health Income Security and Social Services Funding Amount: Case Dependent |
| NIH Blueprint for Neuroscience Research Grand Challenge Developing Novel Drugs for Disorders of the Nervous System (U01) Apply for RFA NS 11 002 Funding Number: RFA NS 11 002 Agency: National Institutes of Health Category: Education Environment Health Income Security and Social Services Funding Amount: Case Dependent |
| Bioengineering Research Partnerships (BRP)R01 Apply for PAR 10 234 Funding Number: PAR 10 234 Agency: National Institutes of Health Category: Education Environment Health Income Security and Social Services Funding Amount: Case Dependent |
| Climate Change and Health Assessing and Modeling Population Vulnerability to Climate Change (R21) Apply for PAR 10 235 Funding Number: PAR 10 235 Agency: National Institutes of Health Category: Education Environment Health Income Security and Social Services Funding Amount: $200,000 |
| Chronic, Non Communicable Diseases and Disorders Across the Lifespan Fogarty International Research Training Award (NCD LIFESPAN) (D43) Apply for PAR 10 257 Funding Number: PAR 10 257 Agency: National Institutes of Health Category: Education Environment Health Income Security and Social Services Funding Amount: Case Dependent |
| Robotics Technology Development and Deployment RTD2 (R43) Apply for PAR 10 279 Funding Number: PAR 10 279 Agency: National Institutes of Health Category: Education Environment Health Income Security and Social Services Funding Amount: $100,000 |
| Limited Competition for the Global Research Initiative Program, Behavioral/Social Sciences (R01) Apply for PAR 10 280 Funding Number: PAR 10 280 Agency: National Institutes of Health Category: Education Environment Health Income Security and Social Services Funding Amount: $50,000 |
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