Opportunity Information: Apply for PA 10 009

  • The National Institutes of Health in the education environment health income security and social services sector is offering a public funding opportunity titled "Bioengineering Research Grants (BRG)(R01)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113 Environmental Health 93.121 Oral Diseases and Disorders Research 93.172 Human Genome Research 93.173 Research Related to Deafness and Communication Disorders 93.242 Mental Health Research Grants 93.273 Alcohol Research Programs 93.279 Drug Abuse and Addiction Research Programs 93.286 Discovery and Applied Research for Technological Innovations to Improve Human Health 93.393 Cancer Cause and Prevention Research 93.394 Cancer Detection and Diagnosis Research 93.395 Cancer Treatment Research 93.396 Cancer Biology Research 93.399 Cancer Control 93.837 Cardiovascular Diseases Research 93.838 Lung Diseases Research 93.839 Blood Diseases and Resources Research 93.846 Arthritis, Musculoskeletal and Skin Diseases Research 93.853 Extramural Research Programs in the Neurosciences and Neurological Disorders 93.859 Biomedical Research and Research Training 93.865 Child Health and Human Development Extramural Research 93.866 Aging Research 93.867 Vision Research.
  • This funding opportunity was created on Mar 8, 2013 and posted on Oct 14, 2009.
  • Applicants must submit their applications by Mar 11, 2013. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Eligible applicants include: Small businesses For profit organizations other than small businesses Native American tribal governments (Federally recognized) Native American tribal organizations (other than Federally recognized tribal governments) Public and State controlled institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) State governments.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:

The Bioengineering Research Grants (BRG) (R01) opportunity (Funding Opportunity Number PA-10-009) is a National Institutes of Health (NIH) discretionary grant program designed to fund basic and applied bioengineering research that tackles important biological, medical, or bioengineering problems. The core idea is to support multidisciplinary projects that use an integrative, systems-style approach to create new knowledge and/or develop methods that can help prevent, detect, diagnose, or treat disease, or improve understanding of health and behavior. The program is flexible in scientific style: proposals can be hypothesis-driven, discovery-driven, developmental, or design-directed, as long as the work is clearly aimed at meaningful bioengineering and biomedical research goals.

The grant uses the NIH Research Project Grant (R01) mechanism, which is the standard NIH mechanism for supporting mature, full research projects with well-developed aims and a solid plan for execution. The announcement also notes that this R01 program runs in parallel with a related funding opportunity for a similar scientific scope under the R21 mechanism (PA-10-010, Exploratory/Developmental Bioengineering Research Grants). In practical terms, that means applicants should consider whether their project fits best as a larger, more fully developed R01 effort (this FOA) or as an earlier-stage, exploratory or development-focused R21 effort (the companion FOA).

A key feature of the BRG program is its emphasis on multidisciplinary work that is still tightly coordinated. Rather than requiring large consortia, the BRGs are intended for research performed in a single lab or by a small number of investigators. That structure is meant to encourage close integration across disciplines (for example, engineering, computation, biology, and medicine) while keeping project management and scientific direction streamlined. The expectation is that applicants will combine methods and concepts across fields in a way that produces advances that would be difficult to achieve within a single traditional discipline.

Funding availability and the number of awards are not guaranteed and depend on NIH budget conditions as well as the volume of high-quality submissions. The announcement explicitly states that awards are contingent on available funds and the submission of a sufficient number of meritorious applications, which is standard NIH language indicating that selection is competitive and dependent on both scientific review outcomes and institute-level funding decisions.

Eligibility is broad and includes many types of organizations. Eligible applicants include public and state-controlled institutions of higher education, private institutions of higher education, nonprofits (including 501(c)(3) organizations and certain nonprofits without 501(c)(3) status), for-profit organizations (including small businesses and other for-profits), state governments, federally recognized tribal governments, and tribal organizations. The opportunity also includes a variety of specialized eligible entities such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, U.S. territories or possessions, regional organizations, and certain non-U.S. (foreign) organizations. The listing indicates no cost-sharing or matching requirement, meaning applicants are not required to provide matching funds as a condition of eligibility.

Administrative details in the source data show the opportunity was posted on October 14, 2009, with later system dates reflecting record creation and archiving. The listed closing dates indicate an original closing date of January 7, 2013, and a current closing date of March 11, 2013, with an archive date of April 11, 2013. The program is associated with a wide range of CFDA numbers spanning environmental health, oral health, genomics, communication disorders, mental health, substance use, technology innovations for health, cancer, cardiovascular and pulmonary diseases, arthritis and musculoskeletal research, neuroscience, child health, aging, and vision research. That wide CFDA coverage signals that multiple NIH Institutes and Centers participate and that the bioengineering focus can align with many different disease areas and health-related topics, as long as the approach and aims fit the BRG purpose.

For applicants seeking the full official announcement and requirements, the funding notice points to the NIH Grants Guide page for PA-10-009 (http://grants.nih.gov/grants/guide/pa-files/PA-10-009.html). It also provides NIH Office of Extramural Research (OER) webmaster contact information for access or linking issues (FBOWebmaster@OD.NIH.GOV), which is mainly for technical problems rather than scientific program questions.

Frequently Asked Questions (FAQs)

1. What is the Bioengineering Research Grants (BRG) (R01) opportunity?

The Bioengineering Research Grants (BRG) (R01) opportunity is an NIH discretionary grant program that funds basic and applied bioengineering research. The supported work is expected to address important biological, medical, or bioengineering problems using an integrative, systems-style approach.

2. What is the Funding Opportunity Number for this program?

The Funding Opportunity Number is PA-10-009.

3. What NIH grant mechanism does this opportunity use?

This opportunity uses the NIH Research Project Grant (R01) mechanism, which is NIH's standard mechanism for supporting mature, full research projects with well-developed aims and a solid execution plan.

4. What kinds of research does BRG (R01) support?

BRG (R01) supports basic and applied bioengineering research that uses multidisciplinary, integrative approaches to create new knowledge and/or develop methods that can help prevent, detect, diagnose, or treat disease, or improve understanding of health and behavior.

5. Does the program require a specific scientific style (for example, only hypothesis-driven work)?

No. The program is described as flexible in scientific style. Proposals may be hypothesis-driven, discovery-driven, developmental, or design-directed, as long as the work is clearly aimed at meaningful bioengineering and biomedical research goals.

6. What does the program mean by a "multidisciplinary" and "integrative" approach?

The BRG emphasis is on combining methods and concepts across fields (for example, engineering, computation, biology, and medicine) in a tightly coordinated way. The intent is to generate advances that would be difficult to achieve within a single traditional discipline.

7. Is this grant intended for large consortia?

No. The program is intended for research performed in a single lab or by a small number of investigators. This structure is meant to support close integration across disciplines while keeping management and scientific direction streamlined.

8. How does this R01 BRG opportunity relate to the companion R21 opportunity?

The announcement notes that this R01 program runs in parallel with a related funding opportunity under the R21 mechanism (PA-10-010, Exploratory/Developmental Bioengineering Research Grants). Applicants are encouraged to consider whether their project is better suited to a larger, more fully developed R01 effort (this FOA) or an earlier-stage exploratory/developmental R21 effort (the companion FOA).

9. Is funding guaranteed if an application is submitted?

No. The announcement states that funding availability and the number of awards are not guaranteed. Awards depend on NIH budget conditions and on receiving a sufficient number of meritorious applications.

10. What types of organizations are eligible to apply?

Eligibility is broad. Eligible applicants include public and state-controlled institutions of higher education, private institutions of higher education, nonprofits (including 501(c)(3) organizations and certain nonprofits without 501(c)(3) status), for-profit organizations (including small businesses and other for-profits), state governments, federally recognized tribal governments, and tribal organizations.

11. Are specialized institution types eligible (for example, HBCUs or Hispanic-serving Institutions)?

Yes. The eligible entity list includes Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, U.S. territories or possessions, regional organizations, and certain non-U.S. (foreign) organizations.

12. Are non-U.S. (foreign) organizations eligible?

Yes. The eligible entities include certain non-U.S. (foreign) organizations.

13. Is cost sharing or matching required?

No. The opportunity indicates there is no cost-sharing or matching requirement.

14. When was this opportunity posted, and what are the listed closing/archive dates?

The opportunity was posted on October 14, 2009. The listed closing dates indicate an original closing date of January 7, 2013, and a current closing date of March 11, 2013. The archive date is April 11, 2013.

15. What do the many CFDA numbers associated with this opportunity indicate?

The program is associated with a wide range of CFDA numbers spanning many health and research areas (for example, environmental health, oral health, genomics, mental health, substance use, cancer, cardiovascular and pulmonary diseases, neuroscience, child health, aging, and vision research). This signals that multiple NIH Institutes and Centers participate and that BRG projects can align with many disease areas and health-related topics, as long as the approach and aims fit the BRG purpose.

16. Where can applicants find the official funding announcement?

The funding notice points to the NIH Grants Guide page for PA-10-009: http://grants.nih.gov/grants/guide/pa-files/PA-10-009.html

17. Who should be contacted for technical problems accessing or linking to the announcement?

For access or linking issues, the announcement provides the NIH Office of Extramural Research (OER) webmaster contact: FBOWebmaster@OD.NIH.GOV. This contact is described as primarily for technical problems rather than scientific program questions.

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