Opportunity Information: Apply for PA 14 114
Apply for PA 14 114
- The National Institutes of Health in the education food and nutrition health sector is offering a public funding opportunity titled "Behavioral Interventions to Address Multiple Chronic Health Conditions in Primary Care (R01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.242 Mental Health Research Grants 93.273 Alcohol Research Programs 93.279 Drug Abuse and Addiction Research Programs 93.361 Nursing Research 93.399 Cancer Control 93.837 Cardiovascular Diseases Research 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research 93.866 Aging Research.
- This funding opportunity was created on Feb 24, 2014 and posted on Feb 24, 2014.
- Applicants must submit their applications by May 7, 2017. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: State governments Independent school districts Small businesses Special district governments For profit organizations other than small businesses Private institutions of higher education City or township governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) Public and State controlled institutions of higher education County governments Native American tribal governments (Federally recognized) Public housing authorities/Indian housing authorities Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments).
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
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Opportunity Summary:
The NIH funding opportunity PA-14-114, titled "Behavioral Interventions to Address Multiple Chronic Health Conditions in Primary Care (R01)," supports research project grant (R01) applications focused on improving outcomes for patients who are living with multiple chronic diseases at the same time. The central idea is to fund behavioral intervention research that can work across conditions using one common conceptual model, rather than stacking separate, disease-specific programs on top of each other. The emphasis is on primary care settings and on approaches that can realistically fit into the way primary care delivers and coordinates care.
This FOA is aimed at patients with three or more chronic health conditions, recognizing that comorbidity is common and that the day-to-day burden of managing multiple diagnoses often makes it harder for patients to follow treatment plans, sustain healthy habits, and avoid preventable complications. Projects are expected to target modifiable health behaviors and demonstrate a plausible pathway from behavior change to measurable improvements in patient-level health outcomes. The interventions should reflect a multi-disease care management approach, meaning they should be designed to address overlapping challenges that cut across conditions (for example, adherence, self-management routines, coping skills, motivation, problem-solving, sleep, physical activity, diet, substance use, stress management, or engagement with care), instead of treating each condition in isolation.
The opportunity explicitly highlights that eligible target conditions can span both physical and behavioral health, and the FOA gives examples such as depression and other mental health disorders, diabetes, smoking, obesity, chronic pain, alcohol and substance abuse or dependence, chronic obstructive pulmonary disease, cancer, and hypertension. That list is not meant to be limiting; it signals NIH interest in proposals that reflect real-world primary care populations where behavioral health and medical conditions are often intertwined. A key expectation is that the proposed intervention uses a shared framework to modify behaviors that influence multiple conditions at once, which can increase impact and feasibility while reducing the complexity of delivering care.
Administratively, this is a discretionary NIH grant using the R01 mechanism. It does not require cost sharing or matching funds. The FOA was posted and created on February 24, 2014, had an original and current closing date of May 7, 2017, and was archived on June 7, 2017. While it is archived (meaning it is no longer accepting applications under that specific announcement), the description remains useful for understanding NIH priorities and for shaping similar proposals under newer NIH notices and parent announcements.
Eligibility is broad and includes many types of U.S.-based organizations that commonly conduct health services and clinical research. Eligible applicants include state, county, city/township, and special district governments; independent school districts; federally recognized tribal governments and other tribal organizations; public housing authorities/Indian housing authorities; public and private institutions of higher education; nonprofit organizations both with and without 501(c)(3) status; and for-profit organizations (including small businesses and other for-profits). The FOA also explicitly lists additional eligible applicant categories such as historically Black colleges and universities (HBCUs), Hispanic-serving institutions, tribally controlled colleges and universities (TCCUs), Alaska Native and Native Hawaiian serving institutions, and Asian American Native American Pacific Islander serving institutions (AANAPISIs), along with faith-based or community-based organizations, regional organizations, U.S. territories or possessions, and eligible federal agencies. At the same time, foreign institutions are not eligible to apply, and non-U.S. components of U.S. organizations are not eligible. Foreign components, as NIH defines them in the NIH Grants Policy Statement, are not allowed under this FOA.
The announcement is associated with multiple CFDA numbers, reflecting cross-cutting relevance to several NIH and HHS research areas, including mental health, alcohol, drug abuse and addiction, nursing research, cancer control, cardiovascular diseases, diabetes/digestive/kidney diseases, and aging research. This reinforces the intent of the FOA: to support intervention research that is not boxed into a single disease silo, but instead addresses the shared behavioral and self-management realities faced by people with complex comorbidity in primary care.
For reference, NIH listed the full announcement link as http://grants.nih.gov/grants/guide/pa-files/PA-14-114.html and provided NIH Office of Extramural Research (OER) webmaster contacts for access or linking issues (FBOWebmaster@OD.NIH.GOV).
FAQs: NIH PA-14-114 - Behavioral Interventions to Address Multiple Chronic Health Conditions in Primary Care (R01)
What is NIH funding opportunity PA-14-114?
PA-14-114 is an NIH Funding Opportunity Announcement (FOA) titled "Behavioral Interventions to Address Multiple Chronic Health Conditions in Primary Care (R01)." It supports R01 research project grant applications focused on improving outcomes for patients living with multiple chronic diseases at the same time through behavioral interventions designed for primary care settings.
What is the main goal of this FOA?
The core goal is to fund behavioral intervention research that can work across multiple chronic conditions using one shared conceptual model, rather than combining separate, disease-specific programs. The focus is on approaches that can realistically fit within how primary care delivers and coordinates care.
What patient population is this FOA focused on?
This opportunity is aimed at patients who have three or more chronic health conditions (multi-morbidity). It reflects the reality that comorbidity is common in primary care and that managing multiple diagnoses can make treatment adherence and healthy behavior change more difficult.
What types of interventions are encouraged?
The FOA emphasizes behavioral interventions that target modifiable health behaviors and are designed to address overlapping challenges that cut across conditions. Examples of cross-cutting targets include adherence, self-management routines, coping skills, motivation, problem-solving, sleep, physical activity, diet, substance use, stress management, and engagement with care.
Does the FOA prefer a single intervention framework over separate disease-specific programs?
Yes. A key expectation is that the proposed intervention uses a shared framework to modify behaviors that influence multiple conditions at once, instead of treating each condition in isolation or stacking multiple disease-specific programs.
What setting is emphasized for this research?
Primary care settings are the main emphasis. The FOA highlights feasibility and fit with the practical workflows of primary care and the way primary care coordinates care for complex patients.
What outcomes should proposed projects aim to improve?
Projects are expected to demonstrate a plausible pathway from behavior change to measurable improvements in patient-level health outcomes. The FOA frames this as moving from modifiable behavior targets to observable health improvements for patients with multiple chronic conditions.
Which chronic conditions are considered relevant under this FOA?
The FOA explicitly notes that target conditions may include both physical and behavioral health conditions. Examples mentioned include depression and other mental health disorders, diabetes, smoking, obesity, chronic pain, alcohol and substance abuse or dependence, chronic obstructive pulmonary disease (COPD), cancer, and hypertension. The list is described as illustrative rather than limiting.
Does this FOA support interventions that span both medical and behavioral health conditions?
Yes. The FOA highlights that eligible target conditions can span physical and behavioral health, reflecting real-world primary care populations where medical conditions and behavioral health concerns are often intertwined.
What grant mechanism does PA-14-114 use?
This is an NIH discretionary grant opportunity using the R01 research project grant mechanism.
Is cost sharing or matching required?
No. The FOA states that it does not require cost sharing or matching funds.
Is PA-14-114 still open for applications?
No. The FOA is archived and is no longer accepting applications under that specific announcement.
When was the FOA posted and when did it close?
The FOA was posted and created on February 24, 2014. It had an original and current closing date of May 7, 2017, and it was archived on June 7, 2017.
If it is archived, is the FOA still useful?
Yes. Even though it is no longer accepting applications, the description can still be useful for understanding NIH priorities and for shaping similar proposals under newer NIH notices and parent announcements.
Who is eligible to apply?
Eligibility is broad and includes many U.S.-based organizations that commonly conduct health services and clinical research. Examples listed include state, county, city/township, and special district governments; independent school districts; federally recognized tribal governments and other tribal organizations; public housing authorities/Indian housing authorities; public and private institutions of higher education; nonprofit organizations with or without 501(c)(3) status; and for-profit organizations (including small businesses).
Are specific institution types explicitly included?
Yes. The FOA explicitly lists categories such as historically Black colleges and universities (HBCUs), Hispanic-serving institutions, tribally controlled colleges and universities (TCCUs), Alaska Native and Native Hawaiian serving institutions, and Asian American Native American Pacific Islander serving institutions (AANAPISIs). It also includes faith-based or community-based organizations, regional organizations, U.S. territories or possessions, and eligible federal agencies.
Are foreign institutions eligible to apply?
No. Foreign institutions are not eligible to apply under this FOA.
Can a U.S. organization include a non-U.S. component?
No. Non-U.S. components of U.S. organizations are not eligible, and foreign components (as defined by NIH in the NIH Grants Policy Statement) are not allowed under this FOA.
What does it mean that the FOA is associated with multiple CFDA numbers?
It indicates cross-cutting relevance to multiple NIH and HHS research areas, such as mental health, alcohol, drug abuse and addiction, nursing research, cancer control, cardiovascular diseases, diabetes/digestive/kidney diseases, and aging research. This supports the FOA's intent to fund interventions that are not confined to a single disease silo.
Where can the full FOA text be found?
NIH listed the full announcement link as http://grants.nih.gov/grants/guide/pa-files/PA-14-114.html
Who can be contacted for access or linking issues to the FOA?
NIH provided NIH Office of Extramural Research (OER) webmaster contact information for access or linking issues: FBOWebmaster@OD.NIH.GOV
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| Consortium for the Study of Chronic Pancreatitis, Diabetes and Pancreatic Cancer Clinical Centers (CSCPDPC CCs) (U01) Apply for RFA DK 14 027 Funding Number: RFA DK 14 027 Agency: National Institutes of Health Category: Education Food and Nutrition Health Funding Amount: $270,000 |
| Consortium for the Study of Chronic Pancreatitis, Diabetes and Pancreatic Cancer Coordination and Data Management Center (CSCPDPC CDMC) (U01) Apply for RFA DK 14 028 Funding Number: RFA DK 14 028 Agency: National Institutes of Health Category: Education Food and Nutrition Health Funding Amount: $1,000,000 |
| Administrative Supplements for Common Basic Sociobehavioral Mechanisms and Processes that Facilitate or Impede Self Management of Chronic Conditions (Admin Supp) Apply for PA 15 122 Funding Number: PA 15 122 Agency: National Institutes of Health Category: Education Food and Nutrition Health Funding Amount: $100,000 |
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| Mechanisms of Alcohol and Drug InducedPancreatitis (R01) Apply for PA 07 067 Funding Number: PA 07 067 Agency: National Institutes of Health Category: Education Food and Nutrition Health Funding Amount: Case Dependent |
| Diet, Epigenetic Events, and Cancer Prevention (R01) Apply for PA 07 175 Funding Number: PA 07 175 Agency: National Institutes of Health Category: Education Food and Nutrition Health Funding Amount: Case Dependent |
| Application of Metabolomics for Translational and Biological Research (R01) Apply for PA 07 301 Funding Number: PA 07 301 Agency: National Institutes of Health Category: Education Food and Nutrition Health Funding Amount: Case Dependent |
| Application of Metabolomics for Translational and Biological Research (R21) Apply for PA 07 302 Funding Number: PA 07 302 Agency: National Institutes of Health Category: Education Food and Nutrition Health Funding Amount: Case Dependent |
| Development of Assays for High Throughput Drug Screening (R01) Apply for PA 07 320 Funding Number: PA 07 320 Agency: National Institutes of Health Category: Education Food and Nutrition Health Funding Amount: Case Dependent |
| Research on the Economics of Diet, Activity, and Energy Balance (R01) Apply for PA 08 078 Funding Number: PA 08 078 Agency: National Institutes of Health Category: Education Food and Nutrition Health Funding Amount: Case Dependent |
| The Effect of Racial and Ethnic Discrimination/Bias on Health Care Delivery (R01) Apply for PA 08 083 Funding Number: PA 08 083 Agency: National Institutes of Health Category: Education Food and Nutrition Health Funding Amount: Case Dependent |
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