Opportunity Information: Apply for PA 15 017
Apply for PA 15 017
- The National Institutes of Health in the education health sector is offering a public funding opportunity titled "Biobehavioral and Technological Interventions to Attenuate Cognitive Decline in Individuals with Cognitive Impairment or Dementia (R01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.361 Nursing Research 93.866 Aging Research.
- This funding opportunity was created on Oct 14, 2014 and posted on Oct 14, 2014.
- Applicants must submit their applications by Jan 7, 2018. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education City or township governments Small businesses Special district governments Private institutions of higher education State governments Native American tribal organizations (other than Federally recognized tribal governments) Native American tribal governments (Federally recognized) For profit organizations other than small businesses Others (see text field entitled Additional Information on Eligibility for clarification) Public and State controlled institutions of higher education Public housing authorities/Indian housing authorities Independent school districts Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education County governments.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:
The National Institutes of Health (NIH) funding opportunity PA 15 017 is an R01 research grant focused on slowing or reducing cognitive decline in people living with dementia, mild cognitive impairment (MCI), or age- or disease-related cognitive decline. The central goal is to support clinical research that tests biobehavioral interventions (for example, behavior change, lifestyle approaches, caregiver-supported strategies, structured routines, training, or psychosocial programs) and technological interventions (such as devices, digital tools, remote monitoring, or other technology-enabled supports) that may help preserve thinking abilities and day-to-day functioning. The opportunity is framed around practical impact: the expectation is that successful interventions will help individuals maintain independence and quality of life, strengthen their capacity to carry out activities of daily living (ADLs) and instrumental activities of daily living (IADLs), and also reduce stress and burden for informal caregivers who often provide the bulk of support.
A key emphasis in the announcement is on interventions that can realistically be implemented in community settings rather than relying only on specialized clinical infrastructure. NIH signals particular interest in approaches that can be used directly by the affected person, by informal caregivers (family members, friends), or by other community-based helpers. This community implementation angle matters because many people with cognitive impairment live at home for long periods and may have limited access to specialty services; the FOA is therefore oriented toward interventions that can scale beyond academic medical centers and fit into real-world routines. In addition to full intervention trials, the FOA also welcomes research that informs the development and refinement of such interventions, which can include preliminary clinical research, feasibility and acceptability work, and studies that help define the most useful components, delivery methods, and target populations.
The FOA also encourages research that goes beyond whether an intervention works to examine how and why it works. This includes studies of underlying mechanisms as well as the use of biomarkers or other objective measures that may be associated with response to an intervention. In practice, this could mean identifying characteristics that predict who benefits most, clarifying biological or behavioral pathways through which an intervention affects cognition, or integrating measures that help explain variability in outcomes. The broader intent is to build a stronger scientific foundation for intervention design and tailoring, so that future programs can be more effective, more targeted, and more efficient to deliver.
From an administrative and eligibility standpoint, this is a discretionary NIH grant opportunity using the R01 mechanism, and it does not require cost sharing or matching. The activity areas are aligned with health and aging research and include CFDA listings 93.361 (Nursing Research) and 93.866 (Aging Research). Eligibility is broad and includes many types of U.S. organizations such as state and local governments, public and private institutions of higher education, nonprofits (including those with or without 501(c)(3) status), small businesses, for-profit organizations other than small businesses, tribal governments and tribal organizations, independent school districts, public housing authorities, and special district governments. The FOA explicitly expands eligibility to additional institution types and groups, including HBCUs, Hispanic-serving institutions, tribally controlled colleges and universities, AANAPISIs, Alaska Native and Native Hawaiian-serving institutions, faith-based and community-based organizations, U.S. territories and possessions, and eligible federal agencies. Foreign organizations and foreign institutions are also eligible to apply, and foreign components of U.S. organizations are permitted consistent with NIH policy.
In terms of timing and status, the opportunity was posted and created on October 14, 2014, had an original and current closing date of January 7, 2018, and was archived on February 7, 2018. The sponsoring agency is the NIH, and the full announcement was provided through the NIH Grants Guide (link: http://grants.nih.gov/grants/guide/pa-files/PA-15-017.html). For technical issues accessing the announcement or problems with links, the contact listed is the NIH Office of Extramural Research (OER) webmaster at FBOWebmaster@OD.NIH.GOV.
Frequently Asked Questions (FAQs) - NIH Funding Opportunity PA-15-017 (R01)
What is NIH funding opportunity PA-15-017?
PA-15-017 is a National Institutes of Health (NIH) funding opportunity announcement for the R01 research grant mechanism. It focuses on clinical research aimed at slowing or reducing cognitive decline in people living with dementia, mild cognitive impairment (MCI), or age- or disease-related cognitive decline.
What is the main goal of this funding opportunity?
The central goal is to support research that tests interventions intended to help preserve thinking abilities and day-to-day functioning. The emphasis is on practical impact, such as helping individuals maintain independence, quality of life, and the ability to perform activities of daily living (ADLs) and instrumental activities of daily living (IADLs), while also reducing stress and burden for informal caregivers.
What types of interventions does the FOA support?
The announcement highlights two broad categories:
- Biobehavioral interventions (examples include behavior change strategies, lifestyle approaches, caregiver-supported strategies, structured routines, training, and psychosocial programs).
- Technological interventions (examples include devices, digital tools, remote monitoring, and other technology-enabled supports).
Does this opportunity focus only on people with dementia?
No. The population of interest includes people living with dementia, mild cognitive impairment (MCI), and people experiencing age- or disease-related cognitive decline.
What outcomes or impacts does NIH expect successful projects to address?
Based on the announcement description, NIH expects interventions that can help:
- Preserve cognition and thinking abilities
- Support day-to-day functioning
- Maintain independence and quality of life
- Strengthen capacity for ADLs and IADLs
- Reduce stress and burden on informal caregivers
Is the FOA limited to studies conducted in specialized clinical settings?
No. A key emphasis is on interventions that can realistically be implemented in community settings and fit into real-world routines, rather than relying only on specialized clinical infrastructure.
Who is expected to deliver or use the interventions?
The FOA signals interest in approaches that can be used directly by the affected person, by informal caregivers (such as family members or friends), or by other community-based helpers.
Does this FOA support only large, full-scale intervention trials?
No. In addition to full intervention trials, the FOA welcomes research that informs the development and refinement of interventions. This can include preliminary clinical research, feasibility and acceptability studies, and research to define useful components, delivery methods, and target populations.
Does the announcement encourage research on how and why an intervention works?
Yes. The FOA encourages research that examines mechanisms and explores how and why interventions work, not just whether they work.
Are biomarkers or objective measures part of the encouraged approach?
Yes. The description notes that studies may incorporate biomarkers or other objective measures associated with response to an intervention, including measures that help explain variability in outcomes.
What does the FOA suggest about tailoring interventions to different people?
The FOA describes an interest in identifying characteristics that predict who benefits most and clarifying biological or behavioral pathways. The broader intent is to strengthen the scientific foundation for intervention design and tailoring so future programs can be more targeted and efficient.
What grant mechanism is used for PA-15-017?
This is an NIH discretionary funding opportunity using the R01 research project grant mechanism.
Is cost sharing or matching required?
No. The opportunity does not require cost sharing or matching.
Which CFDA listings are associated with this opportunity?
The activity areas include CFDA listings 93.361 (Nursing Research) and 93.866 (Aging Research).
What types of organizations are eligible to apply?
Eligibility is broad and includes many types of U.S. organizations, such as:
- State and local governments
- Public and private institutions of higher education
- Nonprofits (with or without 501(c)(3) status)
- Small businesses
- For-profit organizations other than small businesses
- Tribal governments and tribal organizations
- Independent school districts
- Public housing authorities
- Special district governments
Are specific institution types explicitly included?
Yes. The FOA explicitly expands eligibility to additional institution types and groups, including HBCUs, Hispanic-serving institutions, tribally controlled colleges and universities, AANAPISIs, Alaska Native and Native Hawaiian-serving institutions, faith-based and community-based organizations, U.S. territories and possessions, and eligible federal agencies.
Are foreign organizations eligible to apply?
Yes. Foreign organizations and foreign institutions are eligible to apply, and foreign components of U.S. organizations are permitted consistent with NIH policy.
When was this opportunity posted and when did it close?
The opportunity was posted/created on October 14, 2014. The original and current closing date listed is January 7, 2018.
Is this funding opportunity still active?
No. The opportunity was archived on February 7, 2018.
Where can I find the full announcement text?
The full announcement was provided through the NIH Grants Guide at: http://grants.nih.gov/grants/guide/pa-files/PA-15-017.html
Who is the sponsoring agency for PA-15-017?
The sponsoring agency is the National Institutes of Health (NIH).
Who should be contacted for technical issues with the announcement link?
For technical issues accessing the announcement or problems with links, the listed contact is the NIH Office of Extramural Research (OER) webmaster at FBOWebmaster@OD.NIH.GOV.
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Applicants also applied for:
Applicants who have applied for this opportunity (PA 15 017) also looked into and applied for these:
| Funding Opportunity |
|---|
| Biobehavioral and Technological Interventions to Attenuate Cognitive Decline in Individuals with Cognitive Impairment or Dementia (R15) Apply for PA 15 016 Funding Number: PA 15 016 Agency: National Institutes of Health Category: Education Health Funding Amount: $300,000 |
| Limited Competition for the Continuation of Rare Diseases Clinical Research Consortia in the Rare Diseases Clinical Research Network (U54) Apply for PAR 15 019 Funding Number: PAR 15 019 Agency: National Institutes of Health Category: Education Health Funding Amount: $1,250,000 |
| National Cancer Institute Program Project Applications (P01) Apply for PAR 15 023 Funding Number: PAR 15 023 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Mechanistic Studies of Pain and Alcohol Dependence (R01) Apply for PA 15 026 Funding Number: PA 15 026 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Promoting Research in Basic Neuroscience (R01) Apply for PAS 15 029 Funding Number: PAS 15 029 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| The Early Detection Research Network Biomarker Developmental Laboratories (U01) Apply for RFA CA 14 014 Funding Number: RFA CA 14 014 Agency: National Institutes of Health Category: Education Health Funding Amount: $400,000 |
| The Early Detection Research Network Clinical Validation Centers (U01) Apply for RFA CA 14 015 Funding Number: RFA CA 14 015 Agency: National Institutes of Health Category: Education Health Funding Amount: $600,000 |
| The Early Detection Research Network Biomarker Reference Laboratories (U24) Apply for RFA CA 14 016 Funding Number: RFA CA 14 016 Agency: National Institutes of Health Category: Education Health Funding Amount: $300,000 |
| The Early Detection Research Network Data Management and Coordinating Center (U24) Apply for RFA CA 14 017 Funding Number: RFA CA 14 017 Agency: National Institutes of Health Category: Education Health Funding Amount: $4,500,000 |
| Cancer Prevention, Control, Behavioral Sciences, and Population Sciences Career Development Award (K07) Apply for PAR 15 033 Funding Number: PAR 15 033 Agency: National Institutes of Health Category: Education Health Funding Amount: $130,000 |
| Research Aimed at Novel Behavioral Targets to Improve Adolescent Substance Abuse Treatment and Prevention Interventions (R01) Apply for PA 15 036 Funding Number: PA 15 036 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Research Aimed at Novel Behavioral Targets to Improve Adolescent Substance Abuse Treatment and Prevention Interventions (R34) Apply for PA 15 035 Funding Number: PA 15 035 Agency: National Institutes of Health Category: Education Health Funding Amount: $450,000 |
| Cancer Detection, Diagnosis, and Treatment Technologies for Global Health (UH2/UH3) Apply for RFA CA 15 001 Funding Number: RFA CA 15 001 Agency: National Institutes of Health Category: Education Health Funding Amount: $1,000,000 |
| Exploratory Grant Award to Promote Workforce Diversity in Basic Cancer Research (R21) Apply for PAR 15 053 Funding Number: PAR 15 053 Agency: National Institutes of Health Category: Education Health Funding Amount: $275,000 |
| NCI Mentored Clinical Scientist Research Career Development Award to Promote Diversity (K08) Apply for PAR 15 060 Funding Number: PAR 15 060 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| NCI Mentored Patient Oriented Research Career Development Award to Promote Diversity (K23) Apply for PAR 15 062 Funding Number: PAR 15 062 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| NCI Transition Career Development Award to Promote Diversity (K22) Apply for PAR 15 063 Funding Number: PAR 15 063 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| NCI Mentored Research Scientist Development Award to Promote Diversity (K01) Apply for PAR 15 064 Funding Number: PAR 15 064 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| The NCI Transition Career Development Award (K22) Apply for PAR 15 056 Funding Number: PAR 15 056 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Building on High Impact Basic Neurobiology Through Assay Development Advancing Tools for Therapeutic Discovery (R01) Apply for PAR 15 066 Funding Number: PAR 15 066 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
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