Opportunity Information: Apply for PA 09 267
Apply for PA 09 267
- The National Institutes of Health in the education health income security and social services sector is offering a public funding opportunity titled "Bioengineering Nanotechnology Initiative (SBIR R43/44)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.121 Oral Diseases and Disorders Research 93.172 Human Genome Research 93.173 Research Related to Deafness and Communication Disorders 93.233 National Center on Sleep Disorders Research 93.242 Mental Health Research Grants 93.279 Drug Abuse and Addiction Research Programs 93.281 Mental Health Research Career/Scientist Development Awards 93.282 Mental Health National Research Service Awards for Research Training 93.286 Discovery and Applied Research for Technological Innovations to Improve Human Health 93.846 Arthritis, Musculoskeletal and Skin Diseases Research 93.865 Child Health and Human Development Extramural Research 93.866 Aging Research 93.867 Vision Research.
- This funding opportunity was created on Oct 2, 2009 and posted on Oct 2, 2009.
- Applicants must submit their applications by Jan 7, 2010. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Small businesses.
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Opportunity Summary:
The Bioengineering Nanotechnology Initiative (SBIR R43/44), Funding Opportunity Number PA-09-267, was a National Institutes of Health (NIH) trans-NIH grant opportunity designed to push practical, health-focused nanotechnology innovations coming out of small businesses. In this context, nanotechnology is defined in the classic NIH way as the understanding and control of matter at roughly 1 to 100 nanometers, a size range where materials can behave differently than they do at larger scales. The announcement emphasizes that work at this scale often depends on advanced capabilities such as imaging, measuring, modeling, and deliberately manipulating matter, and it frames these capabilities as tools for creating new biomedical applications rather than nanoscience for its own sake. The main goal is straightforward: stimulate small business research and development that uses nanotechnology to create or improve diagnostics and medical interventions intended to treat disease.
This opportunity uses the Small Business Innovation Research (SBIR) grant mechanisms R43 and R44, meaning it supports Phase I projects (early feasibility and proof-of-concept), Phase II projects (more advanced R&D aimed at development and commercialization readiness), and Fast-Track applications (a combined Phase I/Phase II submission pathway intended to shorten the transition between phases when there is a strong development plan). The FOA also notes that it runs in parallel with a companion announcement of the same scientific scope for the Small Business Technology Transfer (STTR) mechanism (PA-09-266, using R41/R42), which is relevant for teams that want or need a formal academic research partner under STTR rules. The SBIR focus here is on small businesses as the primary driver of the innovation effort, with the program structure intended to move ideas from feasibility toward a product or clinically useful capability.
In terms of who could apply, eligibility was limited to small businesses, consistent with SBIR requirements. The funding instrument type is a grant, and the opportunity is categorized as discretionary funding. No cost sharing or matching was required, which typically lowers the barrier to entry for early-stage companies that may not have significant non-federal funds available for R&D.
The announcement does not promise a set number of awards or a guaranteed funding pool; instead, it states that awards are contingent on the availability of funds and on receiving a sufficient number of meritorious applications. In practice, that means the actual number and size of awards would vary depending on NIH budget conditions and on how strong, well-justified, and programmatically relevant the submitted proposals were. The total amount awarded and the number of awards would depend on application quality, project duration, and proposed costs, reflecting a flexible portfolio approach rather than a fixed competition with predetermined award counts.
The scope is broadly biomedical and cross-cutting across NIH, which is reinforced by the wide list of CFDA program areas tied to the FOA. These include, among others, oral diseases (93.121), human genome research (93.172), deafness and communication disorders (93.173), sleep disorders (93.233), mental health research (93.242), drug abuse and addiction programs (93.279), technological innovations to improve human health (93.286), arthritis/musculoskeletal/skin diseases (93.846), child health and human development (93.865), aging research (93.866), and vision research (93.867). That range signals that applicants could target many disease areas or clinical needs, as long as the core innovation leveraged nanoscale science or engineering to enable a diagnostic or therapeutic intervention relevant to human health.
Administratively, the FOA was posted on October 2, 2009, with an original and current closing date of January 7, 2010, and it was archived on February 7, 2010. The primary agency listed is the National Institutes of Health. For applicants or readers who had trouble accessing the electronic announcement, the contact point provided was the NIH Office of Extramural Research (OER) webmaster email. The full announcement was hosted on the NIH grants guide site at the link included in the source data.
Frequently Asked Questions (FAQs)
What is the Bioengineering Nanotechnology Initiative (SBIR R43/44)?
The Bioengineering Nanotechnology Initiative (SBIR R43/44) is an NIH trans-NIH funding opportunity (Funding Opportunity Number PA-09-267) intended to stimulate practical, health-focused nanotechnology innovations originating from small businesses. It supports research and development that uses nanotechnology to create or improve diagnostics and medical interventions intended to treat disease.
Which agency offered this funding opportunity?
The primary agency listed for this opportunity is the National Institutes of Health (NIH).
What is the Funding Opportunity Number (FON)?
The Funding Opportunity Number is PA-09-267.
What type of funding instrument is this?
The funding instrument type is a grant.
Is this considered discretionary funding?
Yes. The opportunity is categorized as discretionary funding.
Who was eligible to apply?
Eligibility was limited to small businesses, consistent with SBIR requirements.
What SBIR mechanisms does this FOA use?
This FOA uses the SBIR grant mechanisms R43 and R44.
What project phases are supported under R43/R44?
The opportunity supports Phase I projects (early feasibility and proof-of-concept) and Phase II projects (more advanced R&D aimed at development and commercialization readiness). It also allows Fast-Track applications that combine Phase I and Phase II into a single submission to shorten the transition between phases when a strong development plan is presented.
What is a Fast-Track application in this context?
A Fast-Track application is a combined Phase I/Phase II submission pathway intended to shorten the transition between phases when there is a strong development plan.
What is the main goal of the initiative?
The main goal is to stimulate small business research and development that uses nanotechnology to create or improve diagnostics and medical interventions intended to treat disease.
How does the FOA define nanotechnology?
Nanotechnology is defined as the understanding and control of matter at roughly 1 to 100 nanometers, a size range where materials can behave differently than they do at larger scales.
What kinds of capabilities does the FOA associate with nanoscale work?
The FOA notes that work at the 1 to 100 nanometer scale often depends on advanced capabilities such as imaging, measuring, modeling, and deliberately manipulating matter, and it frames these as tools for creating new biomedical applications (rather than nanoscience for its own sake).
What kinds of projects are a fit for this announcement?
Projects are a fit when they leverage nanoscale science or engineering to enable a biomedical diagnostic or a medical intervention relevant to human health, with an emphasis on practical, health-focused innovation aimed at treating disease.
Is this opportunity limited to a specific disease area?
No. The scope is broadly biomedical and cross-cutting across NIH. Applicants could target many disease areas or clinical needs, as long as the core innovation uses nanotechnology to enable a diagnostic or therapeutic intervention relevant to human health.
Which CFDA program areas are associated with this FOA?
The FOA is tied to a wide range of CFDA program areas, including: oral diseases (93.121), human genome research (93.172), deafness and communication disorders (93.173), sleep disorders (93.233), mental health research (93.242), drug abuse and addiction programs (93.279), technological innovations to improve human health (93.286), arthritis/musculoskeletal/skin diseases (93.846), child health and human development (93.865), aging research (93.866), and vision research (93.867).
Does this FOA require cost sharing or matching funds?
No. The opportunity states that no cost sharing or matching was required.
Does the announcement specify a set number of awards or a guaranteed funding pool?
No. The announcement does not promise a set number of awards or a guaranteed funding pool. Awards are described as contingent on the availability of funds and on receiving a sufficient number of meritorious applications.
What determines how many awards are made and at what size?
The total number of awards and total dollars awarded would vary based on NIH budget conditions and the strength and relevance of submitted proposals. The FOA indicates that award outcomes depend on application quality, project duration, and proposed costs.
Is there a companion opportunity for teams that need a formal academic research partner?
Yes. The FOA notes that it runs in parallel with a companion announcement of the same scientific scope for the STTR mechanism: PA-09-266, using R41/R42.
How is SBIR positioned in this FOA compared to STTR?
The SBIR focus is on small businesses as the primary driver of the innovation effort. The companion STTR announcement is relevant for teams that want or need a formal academic research partner under STTR rules.
When was this FOA posted?
The FOA was posted on October 2, 2009.
What was the application closing date?
The original and current closing date listed was January 7, 2010.
When was the FOA archived?
The opportunity was archived on February 7, 2010.
Where was the full announcement hosted?
The full announcement was hosted on the NIH grants guide site (via the link referenced in the source data for this opportunity).
Who should be contacted if there were issues accessing the electronic announcement?
The contact point provided for trouble accessing the electronic announcement was the NIH Office of Extramural Research (OER) webmaster email.
Browse more opportunities from the same agency: National Institutes of Health
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Next opportunity: Biobehavioral Research Awards for Innovative New Scientists (BRAINS) (R01)
Previous opportunity: Bioengineering Nanotechnology Initiative (STTR R41/R42
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