Opportunity Information: Apply for PA 09 266
Apply for PA 09 266
- The National Institutes of Health in the education environment health income security and social services sector is offering a public funding opportunity titled "Bioengineering Nanotechnology Initiative (STTR R41/R42" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113 Environmental Health 93.121 Oral Diseases and Disorders Research 93.172 Human Genome Research 93.173 Research Related to Deafness and Communication Disorders 93.233 National Center on Sleep Disorders Research 93.279 Drug Abuse and Addiction Research Programs 93.286 Discovery and Applied Research for Technological Innovations to Improve Human Health 93.846 Arthritis, Musculoskeletal and Skin Diseases Research 93.865 Child Health and Human Development Extramural Research 93.866 Aging Research 93.867 Vision Research.
- This funding opportunity was created on Oct 2, 2009 and posted on Oct 2, 2009.
- Applicants must submit their applications by Jan 7, 2010. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Small businesses.
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Opportunity Summary:
The Bioengineering Nanotechnology Initiative (STTR R41/R42) grant opportunity, identified as PA-09-266, was a National Institutes of Health (NIH) Funding Opportunity Announcement designed to push forward health-related technologies that work at the nanoscale. The core idea behind the program is that materials and devices behave differently when engineered at dimensions of roughly 1 to 100 nanometers, and those unique physical, chemical, and biological properties can be harnessed to create new kinds of medical tools. In practical terms, the FOA sought projects that use nanotechnology methods such as imaging, measurement, modeling, and manipulation of matter at the nanoscale to enable the development of improved diagnostics and therapeutic interventions aimed at preventing, detecting, or treating disease.
This opportunity specifically targeted small businesses through the Small Business Technology Transfer (STTR) mechanism, meaning proposals were expected to involve a formal collaboration between a small business concern and a nonprofit research institution (such as a university or research hospital), consistent with how STTR programs are structured. The funding mechanism supported Phase I (R41), Phase II (R42), and Fast-Track applications, allowing teams to start with early feasibility and proof-of-concept work and, if successful, move into more advanced development and validation efforts. The program also ran in parallel with an SBIR companion announcement (PA-09-267) of the same scientific scope, which offered a similar pathway under the SBIR R43/R44 mechanisms for applicants who fit that program structure better.
From a topic standpoint, the announcement was intentionally broad and trans-NIH, meaning multiple NIH institutes and centers could support relevant nanotechnology-enabled biomedical innovations. This is reflected in the wide range of CFDA numbers associated with the FOA, spanning areas such as environmental health, oral health, human genome research, deafness and communication disorders, sleep disorders, drug abuse and addiction, technological innovations to improve human health, arthritis and musculoskeletal/skin diseases, child health and human development, aging, and vision research. That breadth signaled that nanotechnology approaches were welcomed across many disease areas and clinical needs, as long as the project aligned with NIH missions and demonstrated a credible path toward a useful diagnostic or intervention.
In terms of funding expectations, NIH did not guarantee a fixed number of awards or a set total budget for this FOA. Instead, awards were explicitly dependent on the availability of funds and on how many strong applications were received. The number of awards and total dollars would vary based on application merit, proposed project duration, and budget levels. There was no cost-sharing or matching requirement listed, which is typical for NIH small business grant programs and reduces financial barriers for early-stage R and D.
Administratively, this was a discretionary grant opportunity offered by NIH, with eligibility limited to small businesses. The FOA was posted on October 2, 2009, with an original and current closing date of January 7, 2010, and it was archived on February 7, 2010, indicating it is no longer open. The full announcement was made available through the NIH grants website, and NIH provided contact support through the NIH Office of Extramural Research (OER) webmaster for access or linking issues.
Frequently Asked Questions (FAQs)
What is the Bioengineering Nanotechnology Initiative (STTR R41/R42) opportunity (PA-09-266)?
PA-09-266 was a National Institutes of Health (NIH) Funding Opportunity Announcement (FOA) focused on advancing health-related technologies that operate at the nanoscale, using the STTR grant mechanism (R41/R42).
What was the main scientific focus of PA-09-266?
The FOA aimed to support biomedical innovations that leverage the unique physical, chemical, and biological properties of materials and devices engineered at roughly 1 to 100 nanometers to improve diagnostics and therapeutic interventions for preventing, detecting, or treating disease.
What does "nanoscale" mean in the context of this FOA?
In this announcement, nanoscale generally referred to dimensions of about 1 to 100 nanometers, where materials and devices can behave differently than they do at larger scales.
What types of nanotechnology approaches were encouraged?
The FOA described nanotechnology methods such as imaging, measurement, modeling, and manipulation of matter at the nanoscale, when used to enable improved diagnostics or therapeutic interventions.
Who was eligible to apply?
Eligibility was limited to small businesses applying through the NIH Small Business Technology Transfer (STTR) mechanism.
Did applications need a collaboration partner?
Yes. Because this was an STTR opportunity, proposals were expected to include a formal collaboration between a small business concern and a nonprofit research institution (for example, a university or research hospital), consistent with how STTR programs are structured.
What grant mechanisms were supported under this FOA?
The FOA supported Phase I (R41), Phase II (R42), and Fast-Track applications, allowing teams to pursue early feasibility/proof-of-concept work and then move into more advanced development and validation if successful.
What is the difference between Phase I, Phase II, and Fast-Track as described here?
As described in the FOA summary, Phase I supported early feasibility and proof-of-concept work, Phase II supported more advanced development and validation, and Fast-Track allowed applicants to propose a combined pathway spanning Phase I and Phase II.
Was there a related SBIR opportunity?
Yes. NIH ran a companion SBIR announcement with the same scientific scope, identified as PA-09-267, using the SBIR R43/R44 mechanisms for applicants who fit the SBIR program structure better.
Was the topic area narrow or broad?
The announcement was intentionally broad and trans-NIH, meaning multiple NIH institutes and centers could support nanotechnology-enabled biomedical innovations across many disease areas and clinical needs, as long as projects aligned with NIH missions and aimed toward useful diagnostics or interventions.
What does "trans-NIH" mean for applicants?
It indicated that more than one NIH institute or center could be relevant for funding, reflecting openness to nanotechnology applications across a wide range of biomedical areas.
Which NIH mission areas were associated with PA-09-266?
The FOA listed a broad range of CFDA areas, including environmental health, oral health, human genome research, deafness and communication disorders, sleep disorders, drug abuse and addiction, technological innovations to improve human health, arthritis and musculoskeletal/skin diseases, child health and human development, aging, and vision research.
Did NIH guarantee a certain number of awards or a set total budget?
No. NIH did not guarantee a fixed number of awards or a set total budget under this FOA. Awards depended on the availability of funds and the number of strong applications received.
What factors influenced the number of awards and total funding?
The FOA indicated that award numbers and total dollars could vary based on application merit, proposed project duration, and budget levels, in addition to available funds.
Was cost-sharing or matching required?
No cost-sharing or matching requirement was listed for this FOA.
What type of grant was this from an administrative standpoint?
It was a discretionary grant opportunity offered by NIH.
When was PA-09-266 posted and when did it close?
The FOA was posted on October 2, 2009. The original and current closing date listed was January 7, 2010.
Is this opportunity still open?
No. The FOA was archived on February 7, 2010, indicating it is no longer open.
Where was the full announcement made available?
The full announcement was made available through the NIH grants website.
Who was listed as a support contact for access or linking issues?
NIH provided contact support through the NIH Office of Extramural Research (OER) webmaster for access or linking issues.
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Next opportunity: Bioengineering Nanotechnology Initiative (SBIR R43/44)
Previous opportunity: Community Networks Program (CNP) Centers for Reducing Cancer Disparities through Outreach, Research and Training (U54)
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Applicants also applied for:
Applicants who have applied for this opportunity (PA 09 266) also looked into and applied for these:
| Funding Opportunity |
|---|
| Bioengineering Research Grants (BRG)(R01) Apply for PA 10 009 Funding Number: PA 10 009 Agency: National Institutes of Health Category: Education Environment Health Income Security and Social Services Funding Amount: Case Dependent |
| Exploratory/Developmental Bioengineering Research Grants (EBRG) R21 Apply for PA 10 010 Funding Number: PA 10 010 Agency: National Institutes of Health Category: Education Environment Health Income Security and Social Services Funding Amount: $200,000 |
| Ruth L. Kirschstein National Research Service Award (NRSA) Institutional Research Training Grants (T32) Apply for PA 10 036 Funding Number: PA 10 036 Agency: National Institutes of Health Category: Education Environment Health Income Security and Social Services Funding Amount: Case Dependent |
| Ruth L. Kirschstein National Research Service Award Short Term Institutional Research Training Grants (T35) Apply for PA 10 037 Funding Number: PA 10 037 Agency: National Institutes of Health Category: Education Environment Health Income Security and Social Services Funding Amount: Case Dependent |
| Blueprint Program for Enhancing Neuroscience Diversity through Undergraduate Research Education Experiences (R25) Apply for RFA MH 10 070 Funding Number: RFA MH 10 070 Agency: National Institutes of Health Category: Education Environment Health Income Security and Social Services Funding Amount: Case Dependent |
| Independent Scientist Award (Parent K02) Apply for PA 10 057 Funding Number: PA 10 057 Agency: National Institutes of Health Category: Education Environment Health Income Security and Social Services Funding Amount: Case Dependent |
| NIH Exploratory Developmental Research Grant Program (Parent R21) Apply for PA 10 069 Funding Number: PA 10 069 Agency: National Institutes of Health Category: Education Environment Health Income Security and Social Services Funding Amount: $200,000 |
| Ruth L. Kirschstein National Research Service Awards (NRSA) for Individual Senior Fellows (Parent F33) Apply for PA 10 111 Funding Number: PA 10 111 Agency: National Institutes of Health Category: Education Environment Health Income Security and Social Services Funding Amount: Case Dependent |
| Understanding and Promoting Health Literacy (R03) Apply for PAR 10 134 Funding Number: PAR 10 134 Agency: National Institutes of Health Category: Education Environment Health Income Security and Social Services Funding Amount: Case Dependent |
| Understanding and Promoting Health Literacy (R21) Apply for PAR 10 135 Funding Number: PAR 10 135 Agency: National Institutes of Health Category: Education Environment Health Income Security and Social Services Funding Amount: $200,000 |
| Behavioral and Social Science Research on Understanding and Reducing Health Disparities (R21) Apply for PAR 10 137 Funding Number: PAR 10 137 Agency: National Institutes of Health Category: Education Environment Health Income Security and Social Services Funding Amount: $200,000 |
| Innovative Neuroscience K 12 Education (SBIR R43/R44) Apply for PAR 10 154 Funding Number: PAR 10 154 Agency: National Institutes of Health Category: Education Environment Health Income Security and Social Services Funding Amount: Case Dependent |
| Research on Autism and Autism Spectrum Disorders (R01) Apply for PA 10 158 Funding Number: PA 10 158 Agency: National Institutes of Health Category: Education Environment Health Income Security and Social Services Funding Amount: Case Dependent |
| Research On Autism And Autism Spectrum Disorders (R03) Apply for PA 10 159 Funding Number: PA 10 159 Agency: National Institutes of Health Category: Education Environment Health Income Security and Social Services Funding Amount: Case Dependent |
| Research on Autism and Autism Spectrum Disorders (R21) Apply for PA 10 160 Funding Number: PA 10 160 Agency: National Institutes of Health Category: Education Environment Health Income Security and Social Services Funding Amount: $200,000 |
| International Neuroscience Fellowship (F05) Apply for PAR 10 167 Funding Number: PAR 10 167 Agency: National Institutes of Health Category: Education Environment Health Income Security and Social Services Funding Amount: Case Dependent |
| NIH Blueprint for Neuroscience Research Grand Challenge Developing Novel Drugs for Disorders of the Nervous System (U01) Apply for RFA NS 11 002 Funding Number: RFA NS 11 002 Agency: National Institutes of Health Category: Education Environment Health Income Security and Social Services Funding Amount: Case Dependent |
| Bioengineering Research Partnerships (BRP)R01 Apply for PAR 10 234 Funding Number: PAR 10 234 Agency: National Institutes of Health Category: Education Environment Health Income Security and Social Services Funding Amount: Case Dependent |
| Climate Change and Health Assessing and Modeling Population Vulnerability to Climate Change (R21) Apply for PAR 10 235 Funding Number: PAR 10 235 Agency: National Institutes of Health Category: Education Environment Health Income Security and Social Services Funding Amount: $200,000 |
| Chronic, Non Communicable Diseases and Disorders Across the Lifespan Fogarty International Research Training Award (NCD LIFESPAN) (D43) Apply for PAR 10 257 Funding Number: PAR 10 257 Agency: National Institutes of Health Category: Education Environment Health Income Security and Social Services Funding Amount: Case Dependent |
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