Opportunity Information: Apply for PA 10 149
Apply for PA 10 149
- The National Institutes of Health in the education health income security and social services sector is offering a public funding opportunity titled "Bioengineering Nanotechnology Initiative (STTR R41/R42)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.121 Oral Diseases and Disorders Research 93.172 Human Genome Research 93.173 Research Related to Deafness and Communication Disorders 93.233 National Center on Sleep Disorders Research 93.242 Mental Health Research Grants 93.279 Drug Abuse and Addiction Research Programs 93.286 Discovery and Applied Research for Technological Innovations to Improve Human Health 93.846 Arthritis, Musculoskeletal and Skin Diseases Research 93.865 Child Health and Human Development Extramural Research 93.866 Aging Research 93.867 Vision Research.
- This funding opportunity was created on Apr 6, 2010 and posted on Apr 6, 2010.
- Applicants must submit their applications by May 7, 2013. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Small businesses.
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Opportunity Summary:
The Bioengineering Nanotechnology Initiative (STTR R41/R42), Funding Opportunity Number PA 10 149, is a National Institutes of Health (NIH) discretionary grant opportunity designed to push nanotechnology-based ideas toward real-world medical products and capabilities. The core focus is on using nanotechnology, defined here as working with matter at roughly 1 to 100 nanometers, to take advantage of nanoscale properties that do not appear at larger sizes. The program emphasizes practical biomedical uses of nanoscale science and engineering, including the ability to image, measure, model, and manipulate materials and biological systems at the nanoscale in ways that can lead to new diagnostics and disease treatments.
This announcement is specifically aimed at stimulating applications under the Small Business Technology Transfer (STTR) program. That means the intended applicants are eligible small businesses that will formally partner with a research institution to conduct the work, supporting the broader goal of moving discoveries from the lab into commercial development. The FOA supports the standard STTR staged path: Phase I (R41) for feasibility and proof-of-concept, Phase II (R42) for further development and stronger validation, and a Fast Track option that allows applicants to propose a combined Phase I/Phase II plan for a smoother transition if the project is ready for that level of commitment.
Scientifically, the opportunity is broad and cross-cutting across NIH, reflecting a trans-NIH effort rather than a single institute program. It is intended to cover a wide range of disease areas and technology types as long as nanotechnology is a key enabling feature and the endpoint is a diagnostic or therapeutic intervention relevant to human health. The funding activity categories listed include education, health, and income security/social services, and the associated CFDA numbers span many NIH domains, including oral diseases, human genome research, deafness and communication disorders, sleep disorders, mental health, drug abuse and addiction, technological innovations to improve health, arthritis and musculoskeletal/skin diseases, child health and human development, aging, and vision research. In practical terms, that breadth signals that projects may be relevant to many clinical areas as long as they credibly use nanoscale approaches to solve biomedical problems.
From an administrative standpoint, awards are not guaranteed and depend on annual appropriations, the availability of funds, and the number of strong applications received. NIH also makes clear that the number and size of awards will vary based on the quality of submissions and the proposed project scope, duration, and budget. There is no cost sharing or matching requirement, which reduces barriers for small businesses developing early-stage technologies.
This FOA runs in parallel with a companion announcement of the same scientific scope for the Small Business Innovation Research (SBIR) program (PA 10 150, using R43/R44 mechanisms). The key difference is the commercialization pathway structure: STTR emphasizes a required small business-research institution partnership, while SBIR has different collaboration requirements. For teams deciding between them, the parallel FOAs indicate NIH is encouraging nanotechnology-enabled medical product development through either small-business commercialization route, depending on how the project team and institutional relationships are structured.
The opportunity was posted April 6, 2010, with an original and final closing date of May 7, 2013, and an archive date of June 7, 2013, meaning it is no longer open for new submissions under that specific announcement. The full archived announcement is referenced at http://grants.nih.gov/grants/guide/pa-files/PA-10-149.html, and NIH provides contact points through the Office of Extramural Research (OER) for access or linking issues.
Frequently Asked Questions (FAQs)
What is the Bioengineering Nanotechnology Initiative (STTR R41/R42), PA 10 149?
PA 10 149 is an NIH discretionary funding opportunity under the Small Business Technology Transfer (STTR) program. It is intended to help push nanotechnology-based ideas toward real-world medical products and capabilities, with an emphasis on practical biomedical applications that can lead to new diagnostics and disease treatments.
What does NIH mean by "nanotechnology" in this funding opportunity?
In this announcement, nanotechnology is described as working with matter at roughly 1 to 100 nanometers. The goal is to take advantage of nanoscale properties that do not appear at larger sizes, using nanoscale science and engineering in ways that support biomedical applications.
What kinds of biomedical outcomes is the program trying to support?
The program emphasizes nanotechnology-enabled approaches that can image, measure, model, and manipulate materials and biological systems at the nanoscale, with endpoints aimed at creating or advancing diagnostics and therapeutic interventions relevant to human health.
Who is the intended applicant for this opportunity?
The intended applicants are eligible small businesses applying through the STTR program, which requires a formal partnership with a research institution to conduct the proposed work.
Is a partnership with a research institution required under this FOA?
Yes. Because this announcement is specifically aimed at STTR applications, it is built around a small business formally partnering with a research institution as part of the project structure.
What are the STTR phases supported by PA 10 149?
The FOA supports the standard STTR staged path: Phase I (R41) for feasibility and proof-of-concept, and Phase II (R42) for further development and stronger validation.
What is the Fast Track option mentioned in the announcement?
The Fast Track option allows applicants to propose a combined Phase I/Phase II plan in a single application, aiming for a smoother transition between stages when the project is ready for that level of commitment.
How broad is the scientific scope of this opportunity?
The scientific scope is described as broad and cross-cutting across NIH, reflecting a trans-NIH effort rather than a single institute program. Projects may span many disease areas and technology types, as long as nanotechnology is a key enabling feature and the endpoint is a diagnostic or therapeutic intervention relevant to human health.
Does the FOA focus on a single disease area or institute?
No. It is presented as trans-NIH, meaning it is not limited to one institute or one disease area. The listed CFDA numbers span many NIH domains, signaling relevance across multiple clinical and research areas when nanoscale approaches are central to the solution.
What kinds of disease or research areas might be relevant based on the CFDA examples provided?
The announcement references CFDA coverage across many NIH domains, including oral diseases; human genome research; deafness and communication disorders; sleep disorders; mental health; drug abuse and addiction; technological innovations to improve health; arthritis and musculoskeletal/skin diseases; child health and human development; aging; and vision research.
Are awards guaranteed if an application is submitted?
No. NIH states awards are not guaranteed and depend on annual appropriations, the availability of funds, and the number of strong applications received.
What determines the number and size of awards under this FOA?
NIH indicates the number and size of awards will vary based on the quality of submissions and the proposed project scope, duration, and budget.
Is there a cost sharing or matching requirement?
No. The announcement states there is no cost sharing or matching requirement.
Is this FOA still open for new submissions?
No. It was posted April 6, 2010, with an original and final closing date of May 7, 2013, and an archive date of June 7, 2013. That means it is no longer open for new submissions under that specific announcement.
Where can the archived full announcement be found?
The archived announcement is referenced at http://grants.nih.gov/grants/guide/pa-files/PA-10-149.html.
Is there a related NIH opportunity for SBIR projects?
Yes. This FOA runs in parallel with a companion announcement of the same scientific scope for the Small Business Innovation Research (SBIR) program: PA 10 150, using R43/R44 mechanisms.
What is the key difference between the STTR (PA 10 149) and the companion SBIR (PA 10 150) announcements?
The key difference highlighted is the commercialization pathway structure and collaboration requirements. STTR emphasizes a required small business-research institution partnership, while SBIR has different collaboration requirements.
Why would a team compare the STTR and SBIR companion FOAs?
The parallel FOAs indicate NIH is encouraging nanotechnology-enabled medical product development through either small-business commercialization route, depending on how the project team and institutional relationships are structured.
Who should be contacted for access or linking issues related to the announcement?
NIH provides contact points through the Office of Extramural Research (OER) for access or linking issues.
Browse more opportunities from the same agency: National Institutes of Health
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Previous opportunity: Bioengineering Nanotechnology Initiative (SBIR R43/R44)
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