Opportunity Information: Apply for PA 11 158
Apply for PA 11 158
- The National Institutes of Health in the education health sector is offering a public funding opportunity titled "Biomarkers of Infection Associated Cancers (R01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.121 Oral Diseases and Disorders Research 93.393 Cancer Cause and Prevention Research 93.394 Cancer Detection and Diagnosis Research 93.396 Cancer Biology Research.
- This funding opportunity was created on Mar 17, 2011 and posted on Mar 17, 2011.
- Applicants must submit their applications by May 7, 2014. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification) Special district governments For profit organizations other than small businesses City or township governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses State governments Independent school districts Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education Public and State controlled institutions of higher education Public housing authorities/Indian housing authorities County governments Native American tribal organizations (other than Federally recognized tribal governments) Native American tribal governments (Federally recognized).
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Foreign (non U.S.) components of U.S. Organizations are allowed.
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Opportunity Summary:
The Biomarkers of Infection Associated Cancers (R01) opportunity (Funding Opportunity Number PA-11-158) was a discretionary NIH grant program led by the National Cancer Institute (NCI) with participation from the National Institute of Dental and Craniofacial Research (NIDCR). Its central goal was to support full-scale Research Project Grant (R01) studies focused on discovering and identifying biomarkers for cancers in which an infectious agent plays a causal role in the disease process. In practice, the FOA was aimed at stimulating research that could yield measurable biological indicators tied to infection-driven carcinogenesis, with the longer-term intent of improving cancer risk assessment, early detection, diagnosis, and understanding of disease mechanisms in cancers linked to pathogens.
The program sat within NIH health and education-related research activities and mapped to multiple CFDA program areas, reflecting its broad relevance across cancer etiology, prevention, detection, diagnosis, biology, and oral health. Specifically, it aligned with CFDA 93.121 (Oral Diseases and Disorders Research), 93.393 (Cancer Cause and Prevention Research), 93.394 (Cancer Detection and Diagnosis Research), and 93.396 (Cancer Biology Research). This spread signals that the announcement was not narrowly confined to a single cancer type or tissue site; instead, it was intended to accommodate a range of studies that connect infectious exposures to cancer outcomes, including those with relevance to oral and craniofacial settings that fall under NIDCR interests.
Eligibility was intentionally expansive. Applications could come from a wide variety of domestic and international organizations, including public and private institutions of higher education, nonprofits (both 501(c)(3) and certain non-501(c)(3) entities other than higher education), for-profit organizations (including small businesses and other than small businesses), and multiple levels of government (state, county, city or township, special district governments, and independent school districts). The FOA also explicitly recognized and welcomed participation from institutions and communities that NIH often highlights for inclusive research capacity, such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and tribal governments and organizations (including federally recognized tribes and other tribal entities). Faith-based and community-based organizations were also listed as eligible, and importantly, non-U.S. entities (foreign organizations) could apply, with foreign components of U.S. organizations allowed as well. This structure reflects the global nature of infection-associated cancers and the need for diverse populations and settings to validate biomarkers and understand pathogen-related cancer risk.
From an administrative standpoint, the funding instrument was a grant under the R01 mechanism, which generally supports discrete, investigator-driven research projects of substantial scope. The announcement stated there was no cost-sharing or matching requirement, meaning applicants were not required to contribute non-federal funds as a condition of the award. The FOA was posted and created on March 17, 2011, with an original and final closing date of May 7, 2014, and it was archived on June 7, 2014, indicating it is no longer open for application under that specific announcement.
For those seeking the original text and full details that would have governed application preparation, submission instructions, and any special scientific priorities, NIH provided the official link to the archived FOA at http://grants.nih.gov/grants/guide/pa-files/PA-11-158.html. The contact point listed for access or technical issues was the NIH Office of Extramural Research (OER) webmaster, reachable at FBOWebmaster@OD.NIH.GOV.
Frequently Asked Questions (FAQs): Biomarkers of Infection Associated Cancers (R01) - PA-11-158
What is the Biomarkers of Infection Associated Cancers (R01) opportunity?
It is a discretionary NIH grant program announced as Funding Opportunity Number (FON) PA-11-158. The program used the Research Project Grant (R01) mechanism to support full-scale research studies focused on discovering and identifying biomarkers for cancers where an infectious agent plays a causal role in the disease process.
Which NIH Institutes led or participated in this program?
The program was led by the National Cancer Institute (NCI), with participation from the National Institute of Dental and Craniofacial Research (NIDCR).
What was the central goal of the funding opportunity?
The central goal was to support R01 studies aimed at discovering and identifying measurable biomarkers linked to infection-driven carcinogenesis, with longer-term intent to improve cancer risk assessment, early detection, diagnosis, and understanding of disease mechanisms in cancers linked to pathogens.
What kinds of research did the FOA aim to stimulate?
The FOA aimed to stimulate research that could yield measurable biological indicators tied to cancers caused by infectious agents. These indicators were intended to support improved approaches to assessing risk, detecting cancer early, diagnosing disease, and clarifying how infection-related cancers develop.
What types of cancers were in scope?
Based on the description provided, the scope included cancers in which an infectious agent plays a causal role. The announcement was not described as limited to a single cancer type or tissue site and was intended to accommodate a range of studies connecting infectious exposures to cancer outcomes.
Did the opportunity include oral or craniofacial relevance?
Yes. Participation by NIDCR and alignment with oral health-related program areas indicate the FOA could support studies relevant to oral and craniofacial settings, particularly where infection-associated cancer questions intersect with NIDCR interests.
What funding mechanism was used?
The funding instrument was a grant using the R01 mechanism (Research Project Grant), which typically supports discrete, investigator-driven research projects of substantial scope.
Was cost sharing or matching required?
No. The announcement stated there was no cost-sharing or matching requirement, so applicants were not required to contribute non-federal funds as a condition of the award.
Who was eligible to apply?
Eligibility was broad and included a wide range of domestic and international organizations, including public and private institutions of higher education, nonprofits (including 501(c)(3) and certain non-501(c)(3) organizations other than higher education), for-profit organizations (including small businesses and other than small businesses), and multiple levels of government.
Were government entities eligible, and if so, which types?
Yes. Eligible government applicants included state governments, county governments, city or township governments, special district governments, and independent school districts.
Could small businesses apply?
Yes. For-profit organizations were eligible, explicitly including small businesses as well as other than small businesses.
Were faith-based and community-based organizations eligible?
Yes. The eligibility list included faith-based and community-based organizations.
Were Historically Black Colleges and Universities (HBCUs) eligible?
Yes. HBCUs were explicitly recognized as eligible applicants.
Were Hispanic-serving Institutions eligible?
Yes. Hispanic-serving Institutions were explicitly recognized as eligible applicants.
Were Tribal Colleges and Universities eligible?
Yes. Tribally Controlled Colleges and Universities (TCCUs) were explicitly recognized as eligible applicants.
Were Alaska Native and Native Hawaiian Serving Institutions eligible?
Yes. Alaska Native and Native Hawaiian Serving Institutions were listed among eligible institutions.
Were tribal governments and tribal organizations eligible?
Yes. The FOA welcomed participation from tribal governments and organizations, including federally recognized tribes and other tribal entities.
Could non-U.S. (foreign) organizations apply?
Yes. Non-U.S. entities (foreign organizations) could apply, and foreign components of U.S. organizations were also allowed.
Why did the FOA allow international participation?
The structure reflects the global nature of infection-associated cancers and the need for diverse populations and settings to validate biomarkers and understand pathogen-related cancer risk.
Which CFDA program areas did this funding opportunity align with?
The FOA mapped to multiple CFDA areas: 93.121 (Oral Diseases and Disorders Research), 93.393 (Cancer Cause and Prevention Research), 93.394 (Cancer Detection and Diagnosis Research), and 93.396 (Cancer Biology Research).
What does alignment with multiple CFDA areas suggest about the scope?
It suggests the opportunity was broadly relevant across cancer etiology, prevention, detection, diagnosis, biology, and oral health, rather than being confined to a single narrow topic area.
When was this FOA created and posted?
The FOA was posted and created on March 17, 2011.
What were the closing dates for applications under PA-11-158?
The announcement listed an original closing date and a final closing date of May 7, 2014.
Is this funding opportunity still open?
No. The FOA was archived on June 7, 2014, indicating it is no longer open for application under that specific announcement.
Where can I find the official archived FOA text?
The official archived FOA is available at: http://grants.nih.gov/grants/guide/pa-files/PA-11-158.html.
Who was listed as the contact for access or technical issues?
The contact point listed was the NIH Office of Extramural Research (OER) webmaster at FBOWebmaster@OD.NIH.GOV.
What is the Funding Opportunity Number (FON) for this program?
The Funding Opportunity Number is PA-11-158.
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