Opportunity Information: Apply for PA 11 159
Apply for PA 11 159
- The National Institutes of Health in the education health sector is offering a public funding opportunity titled "Biomarkers of Infection Associated Cancers (R21)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.121 Oral Diseases and Disorders Research 93.393 Cancer Cause and Prevention Research 93.394 Cancer Detection and Diagnosis Research 93.396 Cancer Biology Research.
- This funding opportunity was created on Mar 17, 2011 and posted on Mar 17, 2011.
- Applicants must submit their applications by May 7, 2014. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $275,000.00 in funding.
- Eligible applicants include: Public and State controlled institutions of higher education Native American tribal governments (Federally recognized) Special district governments Others (see text field entitled Additional Information on Eligibility for clarification) State governments Public housing authorities/Indian housing authorities Independent school districts For profit organizations other than small businesses City or township governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Private institutions of higher education Small businesses County governments.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Foreign (non U.S.) components of U.S. Organizations are allowed.
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Opportunity Summary:
The Biomarkers of Infection Associated Cancers (R21) opportunity (Funding Opportunity Number PA 11-159) was a discretionary NIH grant announcement led by the National Cancer Institute (NCI) together with the National Institute of Dental and Craniofacial Research (NIDCR). Its purpose was to push early-stage, exploratory research aimed at identifying biomarkers for cancers in which an infectious agent is a known or suspected cause. In practical terms, the FOA sought projects that could discover or develop measurable biological indicators tied to infection-driven carcinogenesis, with the longer-term goal of improving how these cancers are detected, understood, and ultimately prevented or managed.
The mechanism used was the NIH Exploratory/Developmental Research Grant Award (R21), which is typically meant for high-impact ideas that are still at the proof-of-concept stage. This format supports innovative studies that may not yet have the level of preliminary data expected for larger, more traditional awards, but that could open up new directions for research. The award ceiling listed for the opportunity was $275,000, and the announcement specifically noted that there was no cost sharing or matching requirement, meaning applicants were not required to contribute non-federal funds to be eligible.
From an eligibility standpoint, the announcement was broad and inclusive. Eligible applicants included public and private institutions of higher education, nonprofits (including both 501(c)(3) and non-501(c)(3) organizations), for-profit entities (including small businesses and other for-profits), and multiple levels of government such as state, county, city or township governments, special district governments, and certain housing authorities. It also explicitly included tribal governments and tribal organizations, as well as a range of mission-specific or community-anchored institutions and organizations such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and faith-based or community-based organizations. Importantly, the FOA allowed participation by non-U.S. entities (foreign organizations) and permitted foreign components of U.S. organizations, indicating the NIH was open to international collaboration or research activities when scientifically justified.
The program was categorized under health-related funding activities and aligned with several CFDA program areas, including oral diseases and disorders research (93.121) and multiple cancer research areas spanning cause and prevention, detection and diagnosis, and cancer biology (93.393, 93.394, 93.396). That mix signals the FOA was not limited to one narrow niche; instead, it supported biomarker work that could sit anywhere along the spectrum from etiologic research (linking infections to cancer development) to clinically relevant detection strategies, including cancers affecting oral and craniofacial tissues that fall under NIDCR interests.
In terms of timing, the FOA was posted and created on March 17, 2011, and it ran through an original and final closing date of May 7, 2014, after which it was archived on June 7, 2014. While no longer open, the archived record is still useful for understanding NIH priorities at the time and for modeling future applications to similar biomarker or infection-associated cancer funding announcements.
For reference and full details, the announcement directed applicants to the NIH Grants Guide posting (http://grants.nih.gov/grants/guide/pa-files/PA-11-159.html). It also provided technical contact routing through the NIH Office of Extramural Research (OER) webmaster for access or linking issues (FBOWebmaster@OD.NIH.GOV), reflecting that the listed contact support was primarily for electronic or posting-related problems rather than scientific program consultation.
Frequently Asked Questions (FAQs): Biomarkers of Infection-Associated Cancers (R21) - PA 11-159
What is the title and funding opportunity number for this grant announcement?
The opportunity is titled Biomarkers of Infection Associated Cancers (R21). The Funding Opportunity Number is PA 11-159.
Which agencies or NIH institutes led this funding opportunity?
This was a discretionary NIH grant announcement led by the National Cancer Institute (NCI) together with the National Institute of Dental and Craniofacial Research (NIDCR).
What was the overall purpose of PA 11-159?
The purpose was to support early-stage, exploratory research aimed at identifying biomarkers for cancers where an infectious agent is a known or suspected cause. The longer-term intent was to improve how these cancers are detected, understood, and ultimately prevented or managed.
What type of research did the FOA encourage?
The FOA sought projects that could discover or develop measurable biological indicators tied to infection-driven carcinogenesis. In practice, that means biomarkers connected to the process by which infections contribute to cancer development.
What grant mechanism was used?
The announcement used the NIH Exploratory/Developmental Research Grant Award (R21) mechanism.
What is the R21 mechanism generally intended to support?
R21 awards typically support high-impact, innovative ideas that are still at a proof-of-concept stage. This mechanism can be a fit for projects that may not yet have the level of preliminary data expected for larger, more traditional awards, but that could open new directions for research.
What was the award ceiling for this opportunity?
The award ceiling listed for the opportunity was $275,000.
Was cost sharing or matching required?
No. The announcement specifically stated there was no cost sharing or matching requirement, meaning applicants were not required to contribute non-federal funds to be eligible.
What types of organizations were eligible to apply?
Eligibility was broad. Eligible applicants included:
- Public and private institutions of higher education
- Nonprofits, including both 501(c)(3) and non-501(c)(3) organizations
- For-profit entities, including small businesses and other for-profits
- Government organizations at multiple levels (state, county, city or township, special district governments, and certain housing authorities)
- Tribal governments and tribal organizations
- Mission-specific and community-anchored institutions (for example, HBCUs, Hispanic-serving Institutions, TCCUs, Alaska Native and Native Hawaiian Serving Institutions)
- Faith-based or community-based organizations
Were Historically Black Colleges and Universities (HBCUs) eligible?
Yes. HBCUs were explicitly included as eligible applicants.
Were Hispanic-serving Institutions eligible?
Yes. Hispanic-serving Institutions were explicitly included as eligible applicants.
Were Tribally Controlled Colleges and Universities (TCCUs) eligible?
Yes. TCCUs were explicitly included as eligible applicants.
Were Alaska Native and Native Hawaiian Serving Institutions eligible?
Yes. Alaska Native and Native Hawaiian Serving Institutions were explicitly included as eligible applicants.
Were faith-based or community-based organizations eligible to apply?
Yes. The FOA explicitly included faith-based and community-based organizations among eligible applicants.
Could for-profit organizations apply?
Yes. For-profit entities (including small businesses and other for-profit organizations) were included in the eligible applicant types.
Could government entities apply?
Yes. The FOA included multiple levels of government as eligible applicants, including state governments, county governments, city or township governments, special district governments, and certain housing authorities, as well as tribal governments and tribal organizations.
Were foreign organizations or international collaborations allowed?
Yes. The FOA allowed participation by non-U.S. entities (foreign organizations) and also permitted foreign components of U.S. organizations, indicating that international collaboration or research activities were allowed when scientifically justified.
What type of funding activity was this categorized under?
The program was categorized under health-related funding activities.
Which CFDA program areas were associated with this announcement?
The FOA aligned with several CFDA program areas, including:
- Oral Diseases and Disorders Research (93.121)
- Cancer-related areas covering cause and prevention, detection and diagnosis, and cancer biology (93.393, 93.394, 93.396)
Did this opportunity include oral and craniofacial cancer-related interests?
Yes. The inclusion of NIDCR and the CFDA alignment (including oral diseases and disorders research) indicates the FOA supported biomarker work relevant to cancers affecting oral and craniofacial tissues, in addition to broader cancer and infection-related topics.
Was this FOA limited to a single narrow research niche?
No. The description indicates it was not limited to one narrow niche. It supported biomarker research across a spectrum from etiologic research (linking infections to cancer development) to clinically relevant detection strategies, including areas aligned with NCI and NIDCR.
When was PA 11-159 posted and created?
The FOA was posted and created on March 17, 2011.
What was the closing date for this opportunity?
The announcement ran through an original and final closing date of May 7, 2014.
Is PA 11-159 still open for applications?
No. The opportunity is no longer open. After the final closing date, it was archived on June 7, 2014.
If the FOA is archived, why might it still be useful?
Even though it is no longer open, the archived record can still be useful for understanding NIH priorities at the time and for modeling future applications to similar biomarker or infection-associated cancer funding announcements.
Where can the full announcement be found?
The FOA directed applicants to the NIH Grants Guide posting here: http://grants.nih.gov/grants/guide/pa-files/PA-11-159.html
Who was listed as the contact for technical issues?
For access or linking issues, the announcement routed technical contact through the NIH Office of Extramural Research (OER) webmaster: FBOWebmaster@OD.NIH.GOV.
Was the listed contact intended for scientific or programmatic questions?
Based on the provided information, the listed contact support was primarily for electronic or posting-related problems (access or linking issues), rather than scientific program consultation.
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Previous opportunity: Biomarkers of Infection Associated Cancers (R01)
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Applicants also applied for:
Applicants who have applied for this opportunity (PA 11 159) also looked into and applied for these:
| Funding Opportunity |
|---|
| Enhancing Tumoricidal Activity of Natural Killer (NK) Cells by Dietary Components for Cancer Prevention (R01) Apply for PA 11 160 Funding Number: PA 11 160 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Enhancing Tumoricidal Activity of Natural Killer (NK) Cells by Dietary Components for Cancer Prevention (R21) Apply for PA 11 161 Funding Number: PA 11 161 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| The Effect of Racial and Ethnic Discrimination/Bias on Health Care Delivery (R01) Apply for PA 11 162 Funding Number: PA 11 162 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| The Effect of Racial and Ethnic Discrimination/Bias on Health Care Delivery (R21) Apply for PA 11 163 Funding Number: PA 11 163 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| The Effect of Racial and Ethnic Discrimination/Bias on Health Care Delivery (R03) Apply for PA 11 164 Funding Number: PA 11 164 Agency: National Institutes of Health Category: Education Health Funding Amount: $50,000 |
| Core Infrastructure and Methodological Research for Cancer Epidemiology Cohorts (UM1) Apply for PAR 11 167 Funding Number: PAR 11 167 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Limited Competition for Competitive Revision Applications to Accelerate and Enhance Collaborative Translational Science (UL1) Apply for RFA RR 11 004 Funding Number: RFA RR 11 004 Agency: National Institutes of Health Category: Education Health Funding Amount: $500,000 |
| Short Term Research Enhancement Opportunities for Veterinarians (K18) Apply for RFA RR 11 002 Funding Number: RFA RR 11 002 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Medications Development Program Projects for Substance Related Disorders (P01) Apply for RFA DA 12 005 Funding Number: RFA DA 12 005 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Research Education Program for Laboratory Animal Medicine Veterinarians (R25) Apply for RFA RR 11 003 Funding Number: RFA RR 11 003 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Systems Biology Approaches in HIV/AIDS and Substance Use (R01) Apply for RFA DA 12 009 Funding Number: RFA DA 12 009 Agency: National Institutes of Health Category: Education Health Funding Amount: $650,000 |
| National Cooperative Drug Discovery and Development Groups (NCDDG) for the Treatment of Mental Disorders, Drug or Alcohol Addiction (UM1) Apply for PAR 11 206 Funding Number: PAR 11 206 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| National Cooperative Drug Discovery/Development Groups (NCDDG) for the Treatment of Mental Disorders, Drug or Alcohol Addiction (U19) Apply for PAR 11 207 Funding Number: PAR 11 207 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| NLM Express Research Grants in Biomedical Informatics (R01) Apply for PAR 11 208 Funding Number: PAR 11 208 Agency: National Institutes of Health Category: Education Health Funding Amount: $250,000 |
| NLM Advanced Informatics for Health (R01) Apply for RFA LM 11 002 Funding Number: RFA LM 11 002 Agency: National Institutes of Health Category: Education Health Funding Amount: $250,000 |
| New Technology for Proteomics and Glycomics (STTR R41/R42) Apply for PA 11 214 Funding Number: PA 11 214 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| New Technology for Proteomics and Glycomics (SBIR R43/R44) Apply for PA 11 215 Funding Number: PA 11 215 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Integration of Drug Abuse Prevention and Treatment in Primary Care Settings (R01) Apply for RFA DA 12 008 Funding Number: RFA DA 12 008 Agency: National Institutes of Health Category: Education Health Funding Amount: $500,000 |
| Remote Monitoring System for Detecting Cocaine Ingestion/Intoxication (R01) Apply for RFA DA 12 007 Funding Number: RFA DA 12 007 Agency: National Institutes of Health Category: Education Health Funding Amount: $300,000 |
| Community Clinical Oncology Program Groups (U10) Apply for RFA CA 11 006 Funding Number: RFA CA 11 006 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
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