Opportunity Information: Apply for RFA DA 10 007
Apply for RFA DA 10 007
- The National Institutes of Health in the education health sector is offering a public funding opportunity titled "Cognitive Remediation Approaches to Improve Drug Abuse Treatment Outcomes (R21)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.279 Drug Abuse and Addiction Research Programs.
- This funding opportunity was created on Dec 9, 2009 and posted on Dec 9, 2009.
- Applicants must submit their applications by Apr 7, 2010. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $3,000,000.00 to eligible and selected applicants.
- Each selected applicant is eligible to receive up to $200,000.00 in funding.
- Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification) Small businesses Private institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Special district governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education County governments State governments Public and State controlled institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses Native American tribal governments (Federally recognized) Independent school districts City or township governments Public housing authorities/Indian housing authorities.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:
The National Institute on Drug Abuse (NIDA), under the National Institutes of Health (NIH), released this Funding Opportunity Announcement (FOA) to support early stage, exploratory research aimed at improving treatment outcomes for people with substance use disorders (SUDs). The core idea behind the opportunity is that many individuals with SUDs experience cognitive changes or impairments (for example, problems with attention, memory, executive function, decision making, and self control) that can make it harder to engage in treatment, learn and retain coping skills, follow through on recovery plans, and ultimately maintain abstinence or reduced use. This FOA is looking for projects that design, develop, or refine cognitive remediation strategies specifically intended to strengthen the effectiveness of drug abuse treatment. In practical terms, applicants are expected to propose innovative approaches that target cognition as a lever for improving how well standard SUD interventions work, rather than focusing only on substance use symptoms in isolation.
The mechanism of support is the NIH R21 Exploratory/Developmental Research Grant. R21 awards are typically used to test new ideas, develop novel tools or interventions, generate preliminary evidence, or create a foundation for larger clinical or effectiveness studies later on. This FOA is paired with a companion announcement of the same scientific scope that uses the R01 mechanism (RFA-DA-10-006), which is generally meant for more mature, fully developed projects. In other words, if a research team has an earlier stage concept or needs development and proof-of-concept work first, the R21 track is the intended fit, while more established lines of investigation may align better with the parallel R01.
NIDA indicated an intent to commit about $3,000,000 in total costs (meaning direct costs plus facilities and administrative costs) in fiscal year 2010 across this R21 FOA and the parallel R01 FOA combined. Across both announcements together, the agency anticipated funding roughly 5 to 6 new awards. For this R21 listing, the award ceiling is shown as $200,000 (as presented in the opportunity summary), and there is no cost sharing or matching requirement, which is typical for NIH research grants.
The opportunity is categorized as a discretionary grant within the education and health funding activity area and is associated with CFDA number 93.279 (Drug Abuse and Addiction Research Programs). The FOA was posted on December 9, 2009, with an application closing date of April 7, 2010, and it was archived on May 8, 2010. While it is no longer open, the announcement is useful as a clear example of the kinds of cognitive remediation and treatment enhancement research NIDA has sought to stimulate, particularly work that bridges neuroscience-informed cognition targets with real-world addiction treatment outcomes.
Eligibility for this FOA was broad and included a wide range of U.S. and non-U.S. organizations. Eligible applicants listed include state, county, city, township, and special district governments; public and private institutions of higher education; nonprofits with or without 501(c)(3) status (other than institutions of higher education); for-profit organizations (including those other than small businesses); small businesses; independent school districts; public housing authorities/Indian housing authorities; and Native American tribal governments (both federally recognized and other than federally recognized), as well as Native American tribal organizations. The additional eligibility language also explicitly included groups such as historically black colleges and universities (HBCUs), Hispanic-serving institutions, Alaska Native and Native Hawaiian-serving institutions, tribally controlled colleges and universities (TCCUs), faith-based or community-based organizations, regional organizations, eligible federal agencies, U.S. territories or possessions, and foreign (non-U.S.) entities. This broad eligibility reflects NIH and NIDA interest in encouraging diverse scientific teams, service settings, and community partnerships to tackle cognitive barriers that can undermine addiction treatment success.
For applicants seeking the original posting and full scientific details, the FOA was identified as RFA-DA-10-007, titled "Cognitive Remediation Approaches to Improve Drug Abuse Treatment Outcomes (R21)," and it was hosted on the NIH grants website. The listing also provided technical contact information through the NIH Office of Extramural Research (OER) webmaster for access or linking issues.
Frequently Asked Questions (FAQs)
What is this funding opportunity about?
This Funding Opportunity Announcement (FOA) from the National Institute on Drug Abuse (NIDA), part of the National Institutes of Health (NIH), supports early stage, exploratory research to improve treatment outcomes for people with substance use disorders (SUDs) by targeting cognition (for example attention, memory, executive function, decision making, and self-control) as a way to strengthen drug abuse treatment effectiveness.
What is the main goal of the research supported by this FOA?
The main goal is to design, develop, or refine cognitive remediation strategies intended to enhance how well standard SUD interventions work. The emphasis is on cognition as a lever for improving engagement, learning and retention of coping skills, follow-through on recovery plans, and the ability to maintain abstinence or reduced use.
What kinds of cognitive issues are highlighted as relevant to substance use disorder treatment?
The FOA highlights cognitive changes or impairments that can occur among individuals with SUDs, including difficulties with attention, memory, executive function, decision making, and self-control, which may interfere with treatment participation and long-term recovery outcomes.
Is this FOA focused on treating substance use symptoms alone?
No. The FOA specifically calls for innovative approaches that target cognition to improve the effectiveness of drug abuse treatment, rather than focusing only on substance use symptoms in isolation.
What funding mechanism does this FOA use?
This FOA uses the NIH R21 Exploratory/Developmental Research Grant mechanism, which is commonly used to test new ideas, develop novel tools or interventions, and generate preliminary evidence that can support later, larger studies.
What is an NIH R21 grant generally used for?
Based on the FOA description, R21 awards are typically used to test new concepts, develop and refine approaches, generate early proof-of-concept data, and lay groundwork for subsequent clinical or effectiveness research.
Is there a related funding opportunity using a different NIH mechanism?
Yes. This FOA is paired with a companion announcement with the same scientific scope that uses the R01 mechanism (RFA-DA-10-006). The R01 track is described as being aimed at more mature, fully developed projects.
How should applicants decide between the R21 and the companion R01?
As described in the FOA summary, the R21 is intended for earlier stage concepts needing development and proof-of-concept work, while the parallel R01 is generally meant for more established lines of investigation.
What is the FOA number and title?
The FOA is identified as RFA-DA-10-007 and titled "Cognitive Remediation Approaches to Improve Drug Abuse Treatment Outcomes (R21)."
Which NIH institute is offering this opportunity?
The opportunity was released by the National Institute on Drug Abuse (NIDA) under the National Institutes of Health (NIH).
What is the total amount NIDA intended to commit for this effort?
NIDA indicated an intent to commit about $3,000,000 in total costs in fiscal year 2010 across this R21 FOA and the parallel R01 FOA combined. "Total costs" means direct costs plus facilities and administrative costs.
How many awards were anticipated across the R21 and companion R01 announcements?
Across both announcements together, NIDA anticipated funding roughly 5 to 6 new awards.
What is the award ceiling for this R21 opportunity?
For this R21 listing, the award ceiling is shown as $200,000 (as presented in the opportunity summary).
Is cost sharing or matching required?
No. The FOA states there is no cost sharing or matching requirement.
How is this opportunity categorized?
The opportunity is categorized as a discretionary grant within the education and health funding activity area.
What CFDA number is associated with this opportunity?
The FOA is associated with CFDA number 93.279 (Drug Abuse and Addiction Research Programs).
When was the FOA posted and when did it close?
The FOA was posted on December 9, 2009. The application closing date was April 7, 2010.
Is this FOA currently open for applications?
No. The FOA is archived. It was archived on May 8, 2010, and is no longer open for new applications.
Why might this archived FOA still be useful?
Even though it is no longer open, it serves as a clear example of the types of cognitive remediation and treatment enhancement research NIDA has sought to stimulate, especially work connecting neuroscience-informed cognition targets with real-world addiction treatment outcomes.
Who was eligible to apply?
Eligibility was broad and included a wide range of U.S. and non-U.S. organizations. Eligible applicants listed include state, county, city, township, and special district governments; public and private institutions of higher education; nonprofits with or without 501(c)(3) status (other than institutions of higher education); for-profit organizations (including those other than small businesses); small businesses; independent school districts; public housing authorities/Indian housing authorities; Native American tribal governments (federally recognized and other than federally recognized); and Native American tribal organizations.
Did the eligibility list include minority-serving and community-based organizations?
Yes. The additional eligibility language explicitly included historically black colleges and universities (HBCUs), Hispanic-serving institutions, Alaska Native and Native Hawaiian-serving institutions, tribally controlled colleges and universities (TCCUs), faith-based or community-based organizations, and regional organizations.
Were federal agencies eligible to apply?
Yes. The eligibility language explicitly included eligible federal agencies.
Were U.S. territories or non-U.S. (foreign) organizations eligible?
Yes. The eligibility language explicitly included U.S. territories or possessions and foreign (non-U.S.) entities.
Where was the original FOA hosted?
The FOA was hosted on the NIH grants website.
Who was listed as a technical contact for access or linking issues?
The listing provided technical contact information through the NIH Office of Extramural Research (OER) webmaster for access or linking issues.
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Applicants also applied for:
Applicants who have applied for this opportunity (RFA DA 10 007) also looked into and applied for these:
| Funding Opportunity |
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| Academic Career Award (Parent K07) Apply for PA 10 058 Funding Number: PA 10 058 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Pre Application for the 2010 NIDA Avant Garde Award Program for HIV/AIDS Research (X02) Apply for PAR 10 068 Funding Number: PAR 10 068 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| 2010 NIDA Avant Garde Award Program for HIV/AIDS Research (DP1) Apply for RFA DA 10 012 Funding Number: RFA DA 10 012 Agency: National Institutes of Health Category: Education Health Funding Amount: $500,000 |
| AIDS Malignancy Clinical Trials Consortium (Limited Competition U01) Apply for RFA CA 10 502 Funding Number: RFA CA 10 502 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Mechanism for Time Sensitive Drug Abuse Research (R01) Apply for PAR 10 072 Funding Number: PAR 10 072 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| SBIR Phase II Bridge Awards to Accelerate the Development of Cancer Therapeutics, Imaging Technologies, Interventional Devices, Diagnostics, and Prognostics toward Commercialization (R44) Apply for RFA CA 10 009 Funding Number: RFA CA 10 009 Agency: National Institutes of Health Category: Education Health Funding Amount: $1,000,000 |
| Image Guided Cancer Interventions (SBIR R43/R44) Apply for PA 10 079 Funding Number: PA 10 079 Agency: National Institutes of Health Category: Education Health Funding Amount: $100,000 |
| Image Guided Cancer Interventions (STTR R41/R42) Apply for PA 10 080 Funding Number: PA 10 080 Agency: National Institutes of Health Category: Education Health Funding Amount: $100,000 |
| Shared Instrumentation Grant Program (S10) Apply for PAR 10 082 Funding Number: PAR 10 082 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Systems Biology, HIV/AIDS, and Substance Abuse (R01) Apply for RFA DA 10 014 Funding Number: RFA DA 10 014 Agency: National Institutes of Health Category: Education Health Funding Amount: $750,000 |
| Pre Application for the 2010 NIDA Translational Avant Garde Award for Medication Development for Diseases of Addiction (X02) Apply for PAR 10 095 Funding Number: PAR 10 095 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| 2010 NIDA Translational Avant Garde Award for Medication Development for Diseases of Addiction (DP1) Apply for RFA DA 10 013 Funding Number: RFA DA 10 013 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Medications Development for Substance Related Disorders (R01) Apply for RFA DA 10 018 Funding Number: RFA DA 10 018 Agency: National Institutes of Health Category: Education Health Funding Amount: $1,000,000 |
| Deep Sequencing and Analysis of Pharmacogenomic Regions Discovery and Analysis of Genetic Variants Contributing to Drug Abuse and Addiction (R01) Apply for RFA DA 10 019 Funding Number: RFA DA 10 019 Agency: National Institutes of Health Category: Education Health Funding Amount: $250,000 |
| Institutional Clinical and Translational Science Award (U54) Apply for RFA RM 10 001 Funding Number: RFA RM 10 001 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Technology Based Adherence Interventions for Substance Abusing Populations with HIV (R01) Apply for PAS 10 097 Funding Number: PAS 10 097 Agency: National Institutes of Health Category: Education Health Funding Amount: $250,000 |
| Technology Based Adherence Interventions for Substance Abusing Populations with HIV (R34) Apply for PAS 10 098 Funding Number: PAS 10 098 Agency: National Institutes of Health Category: Education Health Funding Amount: $250,000 |
| Chronic Co Morbid Conditions in HIV U.S. Adults on Highly Effective Anti Retroviral Therapy (R01) Apply for RFA NR 10 001 Funding Number: RFA NR 10 001 Agency: National Institutes of Health Category: Education Health Funding Amount: $500,000 |
| Chronic Co Morbid Conditions in HIV U.S. Adults on Highly Effective Anti Retroviral Therapy (R21) Apply for RFA NR 10 002 Funding Number: RFA NR 10 002 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| Ruth L. Kirschstein National Research Service Awards for Individual Predoctoral Fellows (Parent F31) Apply for PA 10 108 Funding Number: PA 10 108 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
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