Opportunity Information: Apply for RFA AA 12 004
Apply for RFA AA 12 004
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Collaborative Initiative on Fetal Alcohol Spectrum Disorders (CIFASD) (U01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.273 Alcohol Research Programs.
- This funding opportunity was created on Sep 8, 2011 and posted on Sep 8, 2011.
- Applicants must submit their applications by Dec 14, 2011. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $4,000,000.00 to eligible and selected applicants.
- Eligible applicants include: Special district governments Others (see text field entitled Additional Information on Eligibility for clarification) City or township governments Native American tribal governments (Federally recognized) Independent school districts Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses For profit organizations other than small businesses State governments Private institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Public housing authorities/Indian housing authorities Native American tribal organizations (other than Federally recognized tribal governments) County governments Public and State controlled institutions of higher education.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:
The Collaborative Initiative on Fetal Alcohol Spectrum Disorders (CIFASD) (U01) is a National Institutes of Health funding opportunity administered by the National Institute on Alcohol Abuse and Alcoholism (NIAAA) to support a coordinated, multidisciplinary research consortium focused on fetal alcohol spectrum disorders (FASD). The program is structured as a Cooperative Agreement (U01), which means funded projects are expected to operate with substantial NIH scientific involvement and active collaboration across the consortium rather than functioning as fully independent, stand-alone grants. The intent is to bring together domestic and international investigators to accelerate progress in a few targeted, high-impact areas where coordinated effort and shared resources can move the field faster than isolated projects.
The core goal of CIFASD is translational advancement in FASD, specifically improving how FASD is recognized clinically, how neurobehavioral impairments associated with prenatal alcohol exposure are understood and characterized, and how effective interventions and prevention approaches can be developed and tested. On the clinical recognition side, the FOA emphasizes improved diagnosis and better definition of the domains of neurobehavioral impairment, reflecting a need for more precise and reliable ways to identify affected individuals and describe functional outcomes. On the intervention side, the announcement highlights multiple categories of potential approaches, including behavior-based interventions as well as nutritional and/or pharmacological strategies. Prevention is also a central theme, signaling interest in research that reduces risk and incidence through evidence-based public health or clinical approaches. Although the initiative is translational in its aims and coordinates basic, clinical, and translational activities across the consortium, the U01 mechanism under this announcement is intended for basic and clinical research projects only.
This opportunity (Funding Opportunity Number RFA-AA-12-004) was posted on September 8, 2011, with an application closing date of December 14, 2011, and an estimated total funding level of $4,000,000. The FOA indicates no cost sharing or matching requirement, which is typical for many NIH research mechanisms. Because it is a consortium continuation and expansion, it explicitly welcomes applications from both current CIFASD awardees and new applicants, reinforcing the idea that the program is meant to sustain an established collaborative infrastructure while also bringing in new expertise, sites, and research directions aligned with the consortium priorities.
Eligibility is broad and includes many types of U.S. organizations such as state, county, city or township governments; special district governments; independent school districts; public and state-controlled and private institutions of higher education; nonprofit organizations with and without 501(c)(3) status; small businesses; and for-profit organizations other than small businesses. It also includes tribal governments and tribal organizations, public housing authorities/Indian housing authorities, and a range of mission-focused institution types such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and faith-based or community-based organizations. Importantly, the FOA allows participation by non-U.S. entities: foreign institutions may apply, non-U.S. components of U.S. organizations are eligible, and foreign components (as defined by NIH policy) are permitted. This reflects the program's explicit international scope and interest in expanding research capacity and generalizability across different populations and settings.
In practical terms, a competitive CIFASD U01 application under this FOA would be expected to fit within the consortium model by proposing a basic or clinical research project that contributes to shared CIFASD objectives, leverages collaborative opportunities (such as common measures, shared datasets, harmonized protocols, or cross-site recruitment), and supports translation toward better diagnosis, clearer characterization of neurobehavioral outcomes, and improved intervention and prevention strategies for FASD. The full announcement and application instructions were provided through the NIH Grants Guide link included in the FOA, with NIH Office of Extramural Research webmaster contacts listed for technical access or linking issues.
FAQs: Collaborative Initiative on Fetal Alcohol Spectrum Disorders (CIFASD) (U01) - RFA-AA-12-004
What is this funding opportunity?
This opportunity is the Collaborative Initiative on Fetal Alcohol Spectrum Disorders (CIFASD) (U01), a National Institutes of Health (NIH) funding opportunity administered by the National Institute on Alcohol Abuse and Alcoholism (NIAAA). It supports a coordinated, multidisciplinary research consortium focused on fetal alcohol spectrum disorders (FASD).
What is the funding mechanism (U01) and what does it mean for applicants?
The mechanism is a Cooperative Agreement (U01). Under a U01, funded projects are expected to operate with substantial NIH scientific involvement and active collaboration across the consortium, rather than functioning as fully independent, stand-alone grants.
What is the main purpose of CIFASD?
The core goal is translational advancement in FASD by improving clinical recognition, strengthening understanding and characterization of neurobehavioral impairments associated with prenatal alcohol exposure, and developing and testing effective interventions and prevention approaches.
Is this program focused on translational research?
Yes. CIFASD is translational in its aims and coordinates basic, clinical, and translational activities across the consortium. However, under this specific U01 announcement, the mechanism is intended for basic and clinical research projects only.
What research areas are emphasized for clinical recognition and diagnosis?
The FOA emphasizes improved diagnosis and better definition of the domains of neurobehavioral impairment, reflecting a need for more precise and reliable ways to identify affected individuals and describe functional outcomes.
What kinds of intervention approaches are highlighted?
The FOA highlights multiple categories of approaches, including behavior-based interventions as well as nutritional and/or pharmacological strategies.
Is prevention research included?
Yes. Prevention is described as a central theme, signaling interest in research that reduces risk and incidence through evidence-based public health or clinical approaches.
Does the program require a consortium-style, collaborative approach?
Yes. A competitive application would be expected to fit within the consortium model by contributing to shared CIFASD objectives and leveraging collaborative opportunities such as common measures, shared datasets, harmonized protocols, or cross-site recruitment.
Are applications limited to current CIFASD awardees?
No. The FOA explicitly welcomes applications from both current CIFASD awardees and new applicants, reflecting an intent to continue and expand the consortium while bringing in new expertise, sites, and aligned research directions.
Who is the administering NIH institute?
The opportunity is administered by the National Institute on Alcohol Abuse and Alcoholism (NIAAA) within NIH.
What is the Funding Opportunity Number?
The Funding Opportunity Number is RFA-AA-12-004.
When was the opportunity posted and when was the application due?
The FOA was posted on September 8, 2011. The application closing date was December 14, 2011.
How much total funding was estimated for this opportunity?
The estimated total funding level was $4,000,000.
Is cost sharing or matching required?
No. The FOA indicates no cost sharing or matching requirement.
What types of U.S. organizations are eligible to apply?
Eligibility is broad and includes many U.S. organization types, such as state, county, city, or township governments; special district governments; independent school districts; public and state-controlled and private institutions of higher education; nonprofit organizations with and without 501(c)(3) status; small businesses; and for-profit organizations other than small businesses.
Are tribal entities eligible?
Yes. Tribal governments and tribal organizations are included as eligible applicants.
Are public housing authorities eligible?
Yes. Public housing authorities/Indian housing authorities are included as eligible applicants.
Are mission-focused or designated institution types eligible (HBCUs, HSIs, TCCUs, and others)?
Yes. The FOA includes a range of mission-focused institution types, including Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and faith-based or community-based organizations.
Can foreign institutions apply?
Yes. The FOA allows participation by non-U.S. entities. Foreign institutions may apply, non-U.S. components of U.S. organizations are eligible, and foreign components (as defined by NIH policy) are permitted.
Does the FOA encourage international participation?
Yes. The initiative explicitly aims to bring together domestic and international investigators, reflecting an international scope and interest in expanding research capacity and generalizability across different populations and settings.
What would make a CIFASD U01 application competitive under this FOA?
Based on the FOA description, a competitive application would propose a basic or clinical research project that contributes to shared CIFASD objectives, aligns with targeted high-impact areas, leverages consortium collaboration (for example, common measures or harmonized protocols), and supports translation toward improved diagnosis, clearer neurobehavioral characterization, and better interventions and prevention strategies for FASD.
Where were the full announcement details and application instructions provided?
The full announcement and application instructions were provided through the NIH Grants Guide link included in the FOA.
Who could be contacted for technical access or linking issues?
The FOA listed NIH Office of Extramural Research webmaster contacts for technical access or linking issues.
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