Opportunity Information: Apply for RFA AA 12 005

  • The National Institutes of Health in the health sector is offering a public funding opportunity titled "Collaborative Initiative on Fetal Alcohol Spectrum Disorders (CIFASD) (U24)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.273 Alcohol Research Programs.
  • This funding opportunity was created on Sep 8, 2011 and posted on Sep 8, 2011.
  • Applicants must submit their applications by Dec 14, 2011. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $4,000,000.00 to eligible and selected applicants.
  • Eligible applicants include: Native American tribal governments (Federally recognized) Private institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Special district governments County governments City or township governments Others (see text field entitled Additional Information on Eligibility for clarification) Small businesses Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Independent school districts For profit organizations other than small businesses Public housing authorities/Indian housing authorities State governments Native American tribal organizations (other than Federally recognized tribal governments) Public and State controlled institutions of higher education.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed
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Opportunity Summary:

The Collaborative Initiative on Fetal Alcohol Spectrum Disorders (CIFASD) (U24) is a National Institutes of Health (NIH) funding opportunity issued by the National Institute on Alcohol Abuse and Alcoholism (NIAAA) to support the continuation of CIFASD as a coordinated, multidisciplinary research consortium. The program is designed to bring together domestic and international teams to speed progress on fetal alcohol spectrum disorders (FASD) by strengthening collaboration across basic science, clinical research, and translational work. A central emphasis is moving research findings into practical, improved capabilities that can be used in real-world clinical and public health settings, rather than operating as isolated projects.

The scientific focus areas highlighted in the announcement are clinical case recognition, intervention, and prevention. For clinical case recognition, the goal is to improve diagnosis and related tools, including a better understanding of neurobehavioral impairment domains that characterize FASD. On the intervention side, CIFASD encourages work that advances behavior-based approaches as well as nutritional and pharmacological strategies, reflecting the need for a range of evidence-based options that can be applied across different ages and levels of impairment. Prevention is also explicitly included, recognizing that reducing prenatal alcohol exposure and improving early identification and support pathways are both critical to lowering the burden of FASD.

This opportunity uses the Cooperative Agreement U24 mechanism, meaning it is intended to fund support and technical components only, and it operates with substantial NIH program involvement typical of cooperative agreements. In practical terms, the U24 structure is commonly used to enable consortium-level coordination, shared infrastructure, standardization, communication, and other enabling activities that make multi-site, multidisciplinary research function smoothly and produce comparable, integrated outputs. The FOA is aimed at continuing a previously funded initiative, and it is open both to current awardees and to new applicants who can contribute meaningfully to the consortium model and its translational objectives.

Administratively, the funding opportunity number is RFA-AA-12-005, categorized as discretionary funding and listed under CFDA 93.273 (Alcohol Research Programs). The estimated total funding amount is $4,000,000, with no cost sharing or matching requirement. The opportunity was posted on September 8, 2011, with an application closing date of December 14, 2011, and an archive date of January 14, 2012, indicating it is a past competition but still useful as a reference point for how NIAAA structured this consortium and what it prioritized.

Eligibility is broad and includes many organization types across academia, government, nonprofit, and industry. Eligible applicants include public and state-controlled institutions of higher education, private institutions of higher education, nonprofits with and without 501(c)(3) status, small businesses, for-profit organizations other than small businesses, state governments, county and city/township governments, special district governments, independent school districts, public housing authorities/Indian housing authorities, and federally recognized Native American tribal governments, as well as tribal organizations that are not federally recognized. The FOA also explicitly includes Alaska Native and Native Hawaiian Serving Institutions, Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), regional organizations, faith-based or community-based organizations, U.S. territories or possessions, and eligible federal agencies. Importantly, non-U.S. entities (foreign institutions) are eligible to apply, non-U.S. components of U.S. organizations are eligible, and foreign components are allowed under NIH policy, reinforcing the initiative's international consortium character.

For applicants seeking full details, the FOA provided an official NIH link (http://grants.nih.gov/grants/guide/rfa-files/RFA-AA-12-005.html) and directed technical access questions to the NIH Office of Extramural Research (OER) webmaster contacts. Overall, the CIFASD (U24) opportunity is best understood as a consortium-enabling award meant to strengthen the shared infrastructure, coordination, and technical support that allow multiple research efforts to align around improved diagnosis, a clearer picture of neurobehavioral outcomes, more effective interventions, and stronger prevention strategies for FASD.

FAQs: Collaborative Initiative on Fetal Alcohol Spectrum Disorders (CIFASD) (U24)

What is this funding opportunity?

This is an NIH funding opportunity from the National Institute on Alcohol Abuse and Alcoholism (NIAAA) to support the continuation of the Collaborative Initiative on Fetal Alcohol Spectrum Disorders (CIFASD) as a coordinated, multidisciplinary research consortium using the Cooperative Agreement U24 mechanism.

Which NIH institute is sponsoring this opportunity?

The opportunity is issued by the National Institute on Alcohol Abuse and Alcoholism (NIAAA), part of the National Institutes of Health (NIH).

What is CIFASD?

CIFASD is a coordinated, multidisciplinary research consortium intended to accelerate progress on fetal alcohol spectrum disorders (FASD) by strengthening collaboration across basic science, clinical research, and translational work.

What is the main purpose of the CIFASD (U24) award?

The U24 is intended to fund consortium-enabling support and technical components that help a multi-site, multidisciplinary initiative function smoothly, produce comparable outputs, and generate integrated results that can move into real-world clinical and public health settings.

What does the U24 Cooperative Agreement mechanism mean in this FOA?

It means the award supports infrastructure, coordination, standardization, communication, and other enabling activities rather than isolated, stand-alone research projects, and it includes substantial NIH program involvement typical of cooperative agreements.

What research areas does the announcement emphasize?

The FOA highlights three scientific focus areas: clinical case recognition, intervention, and prevention related to FASD.

What does "clinical case recognition" focus on?

Clinical case recognition focuses on improving diagnosis and related tools, including developing a better understanding of the neurobehavioral impairment domains that characterize FASD.

What types of interventions are encouraged under this initiative?

The FOA encourages intervention work that advances behavior-based approaches as well as nutritional and pharmacological strategies, reflecting the need for evidence-based options that can be applied across different ages and levels of impairment.

How is prevention addressed in this opportunity?

Prevention is explicitly included, with an emphasis on reducing prenatal alcohol exposure and improving early identification and support pathways to lower the overall burden of FASD.

Is the program intended to fund individual projects operating independently?

No. A central emphasis is moving findings into practical capabilities for real-world clinical and public health use, supported by a coordinated consortium model rather than isolated projects.

Is this opportunity meant to continue an existing program?

Yes. The FOA is aimed at continuing a previously funded initiative, while still allowing new applicants that can contribute meaningfully to the consortium model and translational objectives.

Who can apply?

Eligibility is broad and includes many organization types across academia, government, nonprofit, and industry, including public and private institutions of higher education, nonprofits (with or without 501(c)(3) status), small businesses, for-profit organizations (including those other than small businesses), and multiple levels of government entities.

Are tribal entities eligible to apply?

Yes. Federally recognized Native American tribal governments are eligible, and tribal organizations that are not federally recognized are also explicitly included.

Are minority-serving institutions included in eligibility?

Yes. The FOA explicitly includes Alaska Native and Native Hawaiian Serving Institutions, Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), and Tribally Controlled Colleges and Universities (TCCUs).

Are community-based or faith-based organizations eligible?

Yes. The FOA explicitly lists faith-based or community-based organizations as eligible applicants.

Are U.S. territories or possessions eligible?

Yes. U.S. territories or possessions are explicitly included among eligible applicants.

Can federal agencies apply?

Yes. The FOA indicates eligible federal agencies can apply.

Are foreign institutions allowed to apply?

Yes. Non-U.S. entities (foreign institutions) are eligible to apply. In addition, non-U.S. components of U.S. organizations are eligible, and foreign components are allowed under NIH policy, consistent with the initiative's international consortium character.

What is the funding opportunity number?

The funding opportunity number is RFA-AA-12-005.

What CFDA program is associated with this FOA?

It is listed under CFDA 93.273 (Alcohol Research Programs).

How much total funding was estimated for this opportunity?

The estimated total funding amount is $4,000,000.

Is cost sharing or matching required?

No. The FOA states there is no cost sharing or matching requirement.

When was the opportunity posted and when did it close?

The opportunity was posted on September 8, 2011, with an application closing date of December 14, 2011.

Is this an active funding opportunity?

No. The archive date is January 14, 2012, indicating it was a past competition, though it may still be useful as a reference for how NIAAA structured this consortium and what it prioritized.

Where can applicants find the official FOA details?

The FOA provided an official NIH link: http://grants.nih.gov/grants/guide/rfa-files/RFA-AA-12-005.html

Where should technical access questions be directed?

The FOA directed technical access questions to the NIH Office of Extramural Research (OER) webmaster contacts.

What kind of outcomes is this consortium trying to enable?

The initiative is oriented toward integrated outputs that strengthen real-world capabilities, including improved diagnosis and tools, clearer characterization of neurobehavioral outcomes, more effective interventions, and stronger prevention strategies for FASD.

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