Opportunity Information: Apply for PAR 12 278
Apply for PAR 12 278
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Collaborative R01s for Clinical and Services Studies of Mental Disorders and AIDS (Collaborative R01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.242 Mental Health Research Grants.
- This funding opportunity was created on Feb 24, 2014 and posted on Sep 7, 2012.
- Applicants must submit their applications by May 7, 2014. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Private institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education County governments City or township governments Public and State controlled institutions of higher education Native American tribal governments (Federally recognized) Special district governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Public housing authorities/Indian housing authorities Small businesses Independent school districts Others (see text field entitled Additional Information on Eligibility for clarification) State governments For profit organizations other than small businesses.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:
The NIH National Institute of Mental Health (NIMH) funding opportunity PAR 12-278, titled "Collaborative R01s for Clinical and Services Studies of Mental Disorders and AIDS (Collaborative R01)," is designed to support multi-site research projects that cannot be completed at a single location. The central idea is that two or more research sites work together under a shared protocol to carry out clinical or services studies focused on mental disorders, including situations where mental disorders occur alongside other conditions (comorbid mental disorders). NIMH is especially interested in collaborative intervention trials that test approaches for treatment, prevention, or rehabilitation, but the announcement also makes clear that other kinds of collaborative clinical studies are appropriate, including mental health services research and studies connected to AIDS, genetics, and psychopathology. The collaborative structure is meant to strengthen the science by increasing overall sample size, speeding up recruitment, and improving the diversity and representativeness of participants across sites.
This FOA uses the R01 research project grant mechanism and is intended for linked, coordinated applications where each participating site submits its own R01 application and has its own Program Director/Principal Investigator. Even though each site is funded and managed as its own R01, the overall project is expected to operate like a single coordinated study, with consistent methods, measures, and implementation across sites. Because multi-site studies create additional logistical and quality challenges, the FOA emphasizes cross-site coordination and shared infrastructure. In larger collaborations, NIMH expects one site to take on the role of coordinating center, handling responsibilities like centralized data management and other administrative functions. Across the linked set of awards, the collaboration should include clear plans for quality control, database management, statistical analysis, and study reporting so the results are integrated and interpretable as one unified project rather than disconnected site-by-site findings.
From an administrative standpoint, this is a discretionary NIH grant opportunity in the health category (CFDA 93.242, Mental Health Research Grants) and it does not require cost sharing or matching. The opportunity was posted September 7, 2012, with key dates indicating that it is now archived (archive date June 7, 2014). The source listing includes an original closing date of May 7, 2015 and a current closing date of May 7, 2014, but because the FOA is archived, it should be treated as no longer active for new submissions under this specific announcement number and date set.
Eligibility is broad and includes many common applicant types for NIH research grants. Eligible applicants include public and private institutions of higher education; nonprofit organizations (including both 501(c)(3) and certain non-501(c)(3) nonprofits); small businesses; for-profit organizations other than small businesses; and a range of government entities such as state, county, city or township governments, special district governments, independent school districts, and public housing/Indian housing authorities. The FOA also explicitly includes a variety of mission- and population-focused institutions and organizations, such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian-serving institutions, and Asian American and Native American Pacific Islander-serving institutions (AANAPISIs), as well as faith-based and community-based organizations and regional organizations. Importantly, non-U.S. entities (foreign institutions) are eligible to apply, non-U.S. components of U.S. organizations are eligible, and foreign components as defined by NIH policy are allowed, which signals that international collaboration is permitted when it is scientifically justified and consistent with NIH requirements.
In practical terms, the projects best aligned with this FOA are those where a single-site study would be underpowered, slow to recruit, or limited in participant diversity, and where a common protocol implemented across multiple locations is essential to answering the research question. Strong applications would be expected to show why the multi-site design is necessary, how the protocol will be implemented consistently, how data will be harmonized and managed, and how the team will maintain oversight across sites to protect study integrity and participant safety. The full announcement is linked through NIH at http://grants.nih.gov/grants/guide/pa-files/PAR-12-278.html, and the contact information in the listing points applicants to the NIH Office of Extramural Research web support (FBOWebmaster@OD.NIH.GOV) for technical access or linking issues.
FAQs: NIH NIMH PAR-12-278 - Collaborative R01s for Clinical and Services Studies of Mental Disorders and AIDS (Collaborative R01)
What is PAR-12-278?
PAR-12-278 is a National Institute of Mental Health (NIMH) NIH funding opportunity titled "Collaborative R01s for Clinical and Services Studies of Mental Disorders and AIDS (Collaborative R01)." It was created to support multi-site clinical or services research studies in mental health (including comorbid mental disorders), including studies connected to AIDS, genetics, and psychopathology, conducted under a shared protocol across two or more research sites.
What is the main purpose of this opportunity?
The purpose is to fund collaborative, multi-site studies that cannot be completed at a single location. The multi-site structure is intended to strengthen the science by increasing total sample size, speeding up recruitment, and improving participant diversity and representativeness across sites.
What types of studies does NIMH emphasize in this FOA?
NIMH is especially interested in collaborative intervention trials testing treatment, prevention, or rehabilitation approaches. The FOA also states that other collaborative clinical studies are appropriate, including mental health services research and studies related to AIDS, genetics, and psychopathology.
Does this FOA require more than one site?
Yes. The central concept is a collaboration of two or more research sites working together under a shared protocol. It is intended for research that cannot be done at a single site.
What makes a project a good fit for a multi-site collaborative R01 under this announcement?
Projects are best aligned when a single-site study would be underpowered, slow to recruit, or limited in participant diversity, and when implementing a common protocol across multiple locations is essential to answering the research question.
What funding mechanism is used?
This FOA uses the NIH R01 research project grant mechanism. Each participating site submits its own R01 application.
How are applications submitted for a collaborative project?
The FOA is intended for linked, coordinated applications. Each participating site submits its own R01 application and has its own Program Director/Principal Investigator, but the awards are expected to operate together like a single coordinated study.
Does each site have its own Principal Investigator (PI)?
Yes. Each participating site has its own Program Director/Principal Investigator for its individual R01 application, even though the overall project is expected to function as one coordinated study.
How is the collaboration expected to function once funded?
Even though each site is funded and managed as its own R01, the overall project is expected to operate like a unified multi-site study with consistent methods, measures, and implementation across sites so results are integrated and interpretable as one project rather than separate site-by-site findings.
What cross-site coordination expectations are described?
The FOA emphasizes cross-site coordination and shared infrastructure to address the added logistical and quality challenges of multi-site studies. It calls for clear plans across the linked awards for quality control, database management, statistical analysis, and study reporting.
Is a coordinating center required?
For larger collaborations, NIMH expects one site to take on the role of a coordinating center. The coordinating center role can include centralized data management and other administrative functions needed to support the unified study.
What kinds of operational plans are expected in the linked set of applications?
The collaboration should include clear plans for quality control, database management, statistical analysis, and study reporting so that data and outcomes are harmonized and reported in a way that supports a single integrated interpretation of the project.
What is the CFDA number and program category listed for this opportunity?
The listing identifies this as a discretionary NIH opportunity in the health category under CFDA 93.242, Mental Health Research Grants.
Is cost sharing or matching required?
No. The opportunity does not require cost sharing or matching.
Is this funding opportunity still active?
No. The key dates indicate the FOA is archived (archive date June 7, 2014). Because it is archived, it should be treated as no longer active for new submissions under this specific announcement number and date set.
What dates are provided in the listing?
The opportunity was posted September 7, 2012. The listing shows an archive date of June 7, 2014. It also lists an original closing date of May 7, 2015 and a current closing date of May 7, 2014, but the archived status indicates it should not be used for new submissions under this FOA.
Who is eligible to apply?
Eligibility is broad and includes public and private institutions of higher education; nonprofit organizations (including 501(c)(3) and certain non-501(c)(3) nonprofits); small businesses; for-profit organizations other than small businesses; and government entities such as state, county, city or township governments, special district governments, independent school districts, and public housing/Indian housing authorities.
Are minority-serving institutions and community or faith-based organizations included in eligibility?
Yes. The FOA explicitly includes organizations such as HBCUs, Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian-serving institutions, AANAPISIs, as well as faith-based organizations, community-based organizations, and regional organizations.
Are non-U.S. (foreign) organizations eligible?
Yes. Non-U.S. entities (foreign institutions) are eligible to apply. The FOA also states that non-U.S. components of U.S. organizations are eligible and that foreign components (as defined by NIH policy) are allowed, indicating international collaboration is permitted when justified and consistent with NIH requirements.
What research focus areas are mentioned besides mental disorders?
In addition to mental disorders (including comorbid mental disorders), the FOA mentions studies connected to AIDS, genetics, and psychopathology, along with mental health services research.
What is the key scientific advantage of the collaborative structure described?
The FOA describes advantages such as increased overall sample size, faster recruitment, and improved diversity and representativeness of participants by enrolling across multiple sites under a shared protocol.
Where can the full announcement be found?
The full announcement is linked through NIH at http://grants.nih.gov/grants/guide/pa-files/PAR-12-278.html.
Who is listed as a contact for technical access or linking issues?
The listing points to NIH Office of Extramural Research web support for technical access or linking issues at FBOWebmaster@OD.NIH.GOV.
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