Opportunity Information: Apply for RFA DA 14 012
Apply for RFA DA 14 012
- The National Institutes of Health in the education health sector is offering a public funding opportunity titled "Comorbid HIV, Chronic Pain, and Substance Use among Older Adults (R21)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.279 Drug Abuse and Addiction Research Programs.
- This funding opportunity was created on Jun 10, 2013 and posted on Jun 10, 2013.
- Applicants must submit their applications by Nov 15, 2013. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $1,000,000.00 to eligible and selected applicants.
- Each selected applicant is eligible to receive up to $200,000.00 in funding.
- Eligible applicants include: Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education County governments Private institutions of higher education Small businesses Others (see text field entitled Additional Information on Eligibility for clarification) Public and State controlled institutions of higher education Public housing authorities/Indian housing authorities State governments For profit organizations other than small businesses City or township governments Independent school districts Native American tribal governments (Federally recognized) Native American tribal organizations (other than Federally recognized tribal governments) Special district governments.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
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Opportunity Summary:
The National Institutes of Health (NIH) Funding Opportunity Announcement RFA-DA-14-012, titled "Comorbid HIV, Chronic Pain, and Substance Use among Older Adults (R21)," was a discretionary grant opportunity focused on improving understanding of how HIV/AIDS intersects with substance use and related health challenges in older adults, with a specific emphasis on chronic pain and drug or alcohol abuse. The overarching intent was to support exploratory, early-stage research that could clarify mechanisms, patterns, and care needs in a population that has often been understudied, while generating practical insights that may inform better prevention and treatment strategies in real-world settings. The mechanism was an R21, which typically supports shorter, more developmental projects aimed at producing foundational evidence, pilot data, or novel approaches that can later be scaled into larger studies.
This FOA was part of a broader 2014 NIH expansion of HIV/AIDS-related research within the context of drug and alcohol abuse, aimed at addressing gaps in knowledge across underserved populations and promising but underexamined service settings. NIH positioned this funding announcement alongside several related initiatives from the same expansion, including efforts focused on HIV and substance use among people who are homeless or unstably housed (RFA-DA-14-009), substance use and HIV among Black/African American women and young men who have sex with men (RFA-DA-14-010), integration of substance use and HIV prevention and treatment into HIV service delivery environments (RFA-DA-14-011), and a coordinating center for Seek, Test, Treat, and Retain data harmonization (RFA-DA-14-007). Taken together, these companion FOAs signal that NIH was aiming to strengthen a coordinated research portfolio that addresses HIV and substance use across multiple high-need groups and care contexts.
From an administrative standpoint, the opportunity was offered as a grant under the health and education activity category, tied to CFDA number 93.279 (Drug Abuse and Addiction Research Programs). The estimated total funding available was $1,000,000, and the award ceiling was $200,000. No cost sharing or matching was required. The FOA was posted on June 10, 2013, with an original and current closing date of November 15, 2013, and it was archived on December 16, 2013, meaning it was time-limited and is no longer open.
Eligibility was broad and included many common U.S.-based applicant types: public and private institutions of higher education, nonprofits (with or without 501(c)(3) status, as long as they were not institutions of higher education in those specific nonprofit categories), small businesses, for-profit organizations other than small businesses, and multiple levels of government (state, county, city/township, special district, and independent school districts). It also included public housing authorities/Indian housing authorities and Native American tribal governments and organizations (including both federally recognized tribal governments and other tribal organizations). The eligibility section also explicitly named a range of institution types and community-focused entities as eligible, such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian-serving institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), as well as faith-based and community-based organizations, regional organizations, eligible federal agencies, and U.S. territories or possessions. At the same time, the FOA clearly excluded non-U.S. (foreign) institutions and applications involving non-U.S. components of U.S. organizations, and it did not allow foreign components as defined by NIH policy.
Programmatically, the central research theme was comorbidity: how HIV infection in older adulthood interacts with chronic pain conditions and substance use, and how those overlapping issues influence health outcomes, risk behaviors, and the effectiveness or delivery of prevention and treatment services. By emphasizing "older adults," the FOA points to an aging HIV population with distinct clinical and social needs, where chronic pain management and substance use risk may complicate HIV care, medication adherence, quality of life, and overall morbidity. The focus on the intersection of HIV/AIDS and drug abuse also reflects a public health priority to understand not just HIV disease management, but the broader behavioral health and pain-related factors that can shape transmission risk, engagement in care, and treatment success.
The sponsoring agency was NIH, and the full announcement was available via the NIH grants guide at the listed link. For technical issues accessing or linking to the announcement, the contact provided was the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.
Frequently Asked Questions (FAQs)
What is the name and identifier of this funding opportunity?
This opportunity is the National Institutes of Health (NIH) Funding Opportunity Announcement (FOA) RFA-DA-14-012, titled "Comorbid HIV, Chronic Pain, and Substance Use among Older Adults (R21)."
What is the main purpose of RFA-DA-14-012?
The purpose was to support exploratory, early-stage research to improve understanding of how HIV/AIDS intersects with substance use and related health challenges in older adults, with specific emphasis on chronic pain and drug or alcohol abuse. The intent was to clarify mechanisms, patterns, and care needs in an understudied population and generate practical insights that could inform prevention and treatment strategies in real-world settings.
What type of award mechanism is this?
The mechanism is an NIH R21 discretionary grant. An R21 typically supports shorter, more developmental projects aimed at producing foundational evidence, pilot data, or novel approaches that can later be scaled into larger studies.
Is this opportunity still open for applications?
No. The FOA was time-limited. It had a closing date of November 15, 2013, and it was archived on December 16, 2013, meaning it is no longer open.
When was the FOA posted, and what were the key dates?
The FOA was posted on June 10, 2013. The original and current closing date was November 15, 2013. It was archived on December 16, 2013.
Which agency sponsored this funding opportunity?
The sponsoring agency was the National Institutes of Health (NIH).
What is the CFDA number associated with this opportunity?
The opportunity was tied to CFDA number 93.279, Drug Abuse and Addiction Research Programs.
How much total funding was estimated to be available?
The estimated total funding available was $1,000,000.
What was the award ceiling (maximum award amount)?
The award ceiling was $200,000.
Was cost sharing or matching required?
No. The FOA stated that no cost sharing or matching was required.
What general topic areas did the FOA focus on?
The central theme was comorbidity: how HIV infection in older adulthood interacts with chronic pain conditions and substance use, and how these overlapping issues influence health outcomes, risk behaviors, and the effectiveness or delivery of prevention and treatment services.
Who was the target population?
The FOA focused on older adults, specifically within the context of HIV/AIDS comorbid with chronic pain and substance use (including drug or alcohol abuse).
Why did the FOA emphasize older adults?
It pointed to an aging HIV population with distinct clinical and social needs, where chronic pain management and substance use risk may complicate HIV care, medication adherence, quality of life, and overall morbidity.
How does this FOA relate to other NIH initiatives mentioned?
This FOA was described as part of a broader 2014 NIH expansion of HIV/AIDS-related research in the context of drug and alcohol abuse. It was positioned alongside related initiatives aimed at strengthening a coordinated research portfolio across multiple high-need groups and service settings.
What are the companion FOAs referenced in the description?
The description referenced these related initiatives: RFA-DA-14-009 (HIV and substance use among people who are homeless or unstably housed), RFA-DA-14-010 (substance use and HIV among Black/African American women and young men who have sex with men), RFA-DA-14-011 (integration of substance use and HIV prevention/treatment into HIV service delivery environments), and RFA-DA-14-007 (a coordinating center for Seek, Test, Treat, and Retain data harmonization).
What category was this opportunity listed under?
Administratively, it was offered as a grant under the health and education activity category.
What types of organizations were eligible to apply?
Eligibility was broad and included public and private institutions of higher education; nonprofits (with or without 501(c)(3) status, as specified in the FOA); small businesses; for-profit organizations other than small businesses; and multiple levels of government (state, county, city/township, special district, and independent school districts). It also included public housing authorities/Indian housing authorities, and Native American tribal governments and organizations (including federally recognized tribal governments and other tribal organizations).
Were minority-serving institutions explicitly included as eligible applicants?
Yes. The eligibility section explicitly named Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian-serving institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISIs) as eligible.
Were faith-based and community-based organizations eligible?
Yes. The FOA explicitly included faith-based and community-based organizations as eligible.
Were U.S. territories or possessions eligible?
Yes. The eligibility list included U.S. territories or possessions.
Were federal agencies eligible to apply?
Yes. The FOA included eligible federal agencies in its eligibility section.
Are foreign (non-U.S.) institutions eligible to apply?
No. The FOA excluded non-U.S. (foreign) institutions.
Are non-U.S. components of U.S. organizations allowed?
No. The FOA excluded applications involving non-U.S. components of U.S. organizations and did not allow foreign components as defined by NIH policy.
Does the FOA mention chronic pain specifically, or is it a general HIV/substance use call?
Chronic pain is a specific emphasis of this FOA, alongside HIV and substance use (including drug or alcohol abuse) among older adults.
What kinds of impacts was this FOA aiming to support?
Based on the description, NIH aimed to support research that could improve understanding of mechanisms and patterns of comorbidity and generate practical insights to inform better prevention and treatment strategies, including implications for engagement in care, delivery of services, and treatment success in real-world settings.
Where could applicants find the full announcement?
The full announcement was available via the NIH grants guide at the link referenced in the opportunity description.
Who should be contacted for technical issues accessing or linking to the announcement?
For technical issues accessing or linking to the announcement, the contact provided was the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.
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