Opportunity Information: Apply for PA 14 196
Apply for PA 14 196
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Complex Technologies and Therapeutics Development for Mental Health Research and Practice (R41/R42)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.242 Mental Health Research Grants.
- This funding opportunity was created on Apr 30, 2014 and posted on Apr 30, 2014.
- Applicants must submit their applications by May 7, 2017. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Small businesses.
- Other Eligible Applicants include the following Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, may be allowed.
[Watch] Creating a grant proposal using the step-by-step wizard inside the applicant portal:
Opportunity Summary:
The grant opportunity titled "Complex Technologies and Therapeutics Development for Mental Health Research and Practice (R41/R42)" is a National Institutes of Health (NIH) funding announcement issued by the National Institute of Mental Health (NIMH) under the Small Business Technology Transfer (STTR) program. Its core purpose is to help small businesses, working in formal partnership with a research institution, move forward on research-and-development projects that produce tangible technologies or therapeutics aligned with NIMH's mission. The emphasis is on innovations that can meaningfully improve how mental disorders are studied, detected, treated, and ultimately how evidence-based mental health care is delivered in real-world settings.
A central feature of this opportunity is its focus on "complex technologies" and therapeutics that are too ambitious to fit comfortably within the usual STTR budget and timeline limits. In practice, that means NIMH is signaling interest in projects that may require more time, specialized expertise, more advanced engineering or scientific development, and larger resource commitments than a typical early-stage small business R&D effort. The goal is not just to explore an idea, but to support substantial development work that helps move a sophisticated product or platform closer to practical use in research, clinical care, or service delivery.
The scientific and public health scope is broad but clearly tied to mental health. NIMH highlights several areas where supported technologies could have impact: basic neuroscience research relevant to mental disorders (for example, tools that enable better measurement or manipulation of brain and behavior processes), translational and clinical research (such as platforms that bridge laboratory findings into human testing), clinical diagnosis or treatment (including novel therapeutics, devices, or software-enabled interventions), and dissemination of evidence-based mental health care (tools that help proven interventions reach clinicians, patients, or communities more effectively). Overall, the announcement is structured to encourage proposals that do more than generate knowledge; it prioritizes work that results in usable, scalable solutions that advance mental health research and practice.
Mechanistically, the funding uses the NIH STTR phased award structure, listed here as R41/R42. The R41 phase is generally associated with early proof-of-concept and feasibility work, while the R42 phase supports further development and validation toward a deployable product. While the source text does not detail budget caps, review criteria, or exact phase lengths, it explicitly states that this funding announcement is intended for projects requiring funding levels and durations beyond what is typical under standard STTR guidelines, reinforcing the idea that NIMH expects higher-complexity development programs.
From an administrative standpoint, this was a discretionary grant opportunity in the health category, tied to CFDA number 93.242 (Mental Health Research Grants). It did not require cost sharing or matching, which is important for small businesses that may have limited ability to contribute non-federal funds. The opportunity was posted and created on April 30, 2014, and it carried an original and current closing date of May 7, 2017, with an archive date of June 7, 2017, meaning it is no longer open for new applications under that specific announcement number.
Eligibility was limited primarily to small businesses, consistent with the STTR program. The notice also clarifies restrictions on foreign participation: non-U.S. (foreign) entities are not eligible to apply, and non-U.S. components of U.S. organizations are also not eligible. However, foreign components as defined by the NIH Grants Policy Statement may be allowed in some circumstances, which typically means certain project elements can occur outside the United States if they are well-justified and meet NIH policy requirements. Applicants would still need to ensure their overall organizational eligibility and compliance with NIH rules governing STTR partnerships, subcontracting arrangements, and project leadership.
For applicants looking for the official announcement and full details, the funding opportunity number is PA-14-196, and the full text was made available through the NIH grants guide at http://grants.nih.gov/grants/guide/pa-files/PA-14-196.html. The contact listed for access or technical issues is the NIH Office of Extramural Research (OER) webmaster at FBOWebmaster@OD.NIH.GOV, which is primarily intended for troubleshooting announcement access rather than scientific or programmatic questions.
FAQs: Complex Technologies and Therapeutics Development for Mental Health Research and Practice (R41/R42) (PA-14-196)
What is the title of this grant opportunity?
The opportunity is titled "Complex Technologies and Therapeutics Development for Mental Health Research and Practice (R41/R42)."
Which agency and institute issued this funding announcement?
This is a National Institutes of Health (NIH) funding announcement issued by the National Institute of Mental Health (NIMH).
What program mechanism does this opportunity use?
It uses the NIH Small Business Technology Transfer (STTR) program and follows the phased award structure R41/R42.
What is the main purpose of this opportunity?
The core purpose is to help small businesses, working in a formal partnership with a research institution, advance research-and-development projects that produce tangible technologies or therapeutics aligned with NIMH's mental health mission.
What does NIMH mean by "complex technologies" in this announcement?
The announcement emphasizes technologies and therapeutics that are too ambitious to fit comfortably within typical STTR budget and timeline limits, implying projects may need more time, specialized expertise, advanced development work, and larger resource commitments than standard early-stage efforts.
What kinds of outcomes does NIMH appear to prioritize?
The emphasis is on substantial development work that moves sophisticated products or platforms closer to practical use in research, clinical care, or service delivery, rather than only generating knowledge.
What mental health areas or stages of research and practice are in scope?
The scope is broad but tied to mental health, including: basic neuroscience research relevant to mental disorders, translational and clinical research, clinical diagnosis or treatment (including therapeutics, devices, or software-enabled interventions), and dissemination of evidence-based mental health care in real-world settings.
Does this opportunity support therapeutics as well as technologies?
Yes. The announcement explicitly references both technologies and therapeutics, with an emphasis on development toward usable solutions for mental health research and practice.
What is the difference between the R41 and R42 phases?
In the STTR phased structure described here, R41 is generally associated with early proof-of-concept and feasibility work, while R42 supports further development and validation toward a deployable product.
Does the announcement specify exact budgets, review criteria, or phase lengths?
Not in the information provided here. The text notes that budget caps, review criteria, and exact phase lengths are not detailed in the source excerpt, while emphasizing that projects may require funding levels and durations beyond typical STTR guidelines.
What type of grant is this classified as?
It is described as a discretionary grant opportunity in the health category.
What CFDA number is associated with this opportunity?
The CFDA number listed is 93.242 (Mental Health Research Grants).
Is cost sharing or matching required?
No. The opportunity states that it did not require cost sharing or matching.
Who is eligible to apply?
Eligibility was limited primarily to small businesses, consistent with the STTR program, and the opportunity expects a formal partnership with a research institution.
Are foreign (non-U.S.) organizations eligible to apply?
No. The notice states that non-U.S. (foreign) entities are not eligible to apply.
Are non-U.S. components of U.S. organizations eligible?
No. The notice also states that non-U.S. components of U.S. organizations are not eligible.
Are any foreign components allowed at all?
Potentially, yes. The notice indicates that foreign components, as defined by the NIH Grants Policy Statement, may be allowed in some circumstances (typically meaning certain project elements can occur outside the United States if well-justified and consistent with NIH policy).
What does this opportunity require in terms of partnership structure?
It is an STTR opportunity, which is described here as requiring small businesses to work in a formal partnership with a research institution. Applicants would also need to comply with NIH rules governing STTR partnerships and related arrangements.
What is the funding opportunity number (FOA number) for this announcement?
The funding opportunity number is PA-14-196.
Where can applicants find the official full announcement text?
The full text was made available through the NIH grants guide at http://grants.nih.gov/grants/guide/pa-files/PA-14-196.html.
Is this funding opportunity still open?
No. The opportunity listed an original and current closing date of May 7, 2017, and an archive date of June 7, 2017, which means it is no longer open for new applications under that specific announcement number.
When was this opportunity posted and created?
It was posted and created on April 30, 2014.
Who is the listed contact, and what are they responsible for?
The listed contact is the NIH Office of Extramural Research (OER) webmaster at FBOWebmaster@OD.NIH.GOV, intended primarily for troubleshooting access or technical issues related to the announcement (not for scientific or programmatic questions).
Browse more opportunities from the same agency: National Institutes of Health
Browse more opportunities from the same category: Health
Next opportunity: Complex Technologies and Therapeutics Development for Mental Health Research and Practice (R43/R44)
Previous opportunity: Idaho BLM Boise District Collegiate Resource Management
USGrants.org Applicant Portal:
Are you interested in learning about about how to apply for this government funding opportunity? You can create a free applicant account and receive instant access to our applicant portal that many business owners like you have benefited from.
Apply for PA 14 196
[Watch] how do funding administrators access proposals?
Applicants also applied for:
Applicants who have applied for this opportunity (PA 14 196) also looked into and applied for these:
| Funding Opportunity |
|---|
| Complex Technologies and Therapeutics Development for Mental Health Research and Practice (R43/R44) Apply for PA 14 197 Funding Number: PA 14 197 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| EPT 2, One Health Workforce Apply for RFA OAA 14 000023 Funding Number: RFA OAA 14 000023 Agency: Agency for International Development Category: Health Funding Amount: $50,000,000 |
| American Indians Into Medicine Apply for HHS 2014 IHS INMED 0001 Funding Number: HHS 2014 IHS INMED 0001 Agency: Indian Health Service Category: Health Funding Amount: $195,000 |
| Unconventional Roles of Ethanol Metabolizing Enzymes, Metabolites, and Cofactors in Health and Disease (R01) Apply for PA 14 198 Funding Number: PA 14 198 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| NIAMS Clinical Trial Implementation Cooperative Agreement (U01) Apply for PAR 14 200 Funding Number: PAR 14 200 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| NIAMS Clinical Trial Planning Cooperative Agreement (U34) Apply for PAR 14 199 Funding Number: PAR 14 199 Agency: National Institutes of Health Category: Health Funding Amount: $250,000 |
| Sudden Death in the Young (SDY) Registry Apply for CDC RFA DP14 1403 Funding Number: CDC RFA DP14 1403 Agency: NCCDPHP Category: Health Funding Amount: $200,000 |
| NEI Administrative Supplements to Small Business Innovative Research (SBIR) Grants for the Procurement of Expertise in the Federal Regulatory Approval Process for New Drugs and/or Devices (Admin Supp) Apply for PA 14 205 Funding Number: PA 14 205 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Strengthening a network of immunization programs to support the NCIRD mission to prevent disease through immunization Apply for CDC RFA IP14 1402 Funding Number: CDC RFA IP14 1402 Agency: Centers for Disease Control and Prevention Category: Health Funding Amount: $700,000 |
| Enhancing Cancer Registries for Early Case Capture (ECC) of Pediatric and Young Adult Cancer (PYAC) Cases Apply for CDC RFA DP14 1402 Funding Number: CDC RFA DP14 1402 Agency: Centers for Disease Control and Prevention Category: Health Funding Amount: Case Dependent |
| Enhancing Cancer Genomic Best Practices through Education, Surveillance, and Policy Apply for CDC RFA DP14 1407 Funding Number: CDC RFA DP14 1407 Agency: Centers for Disease Control and Prevention Category: Health Funding Amount: $350,000 |
| HIV Vaccine Research and Design (HIVRAD) Program (P01) Apply for PAR 14 206 Funding Number: PAR 14 206 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Protecting and Improving Public Health Globally Building and Strengthening Public Health Impact, Systems, Capacity and Security Apply for CDC RFA GH14 1418 Funding Number: CDC RFA GH14 1418 Agency: Centers for Disease Control and Prevention Category: Health Funding Amount: Case Dependent |
| Center for Inherited Disease Research (CIDR) High Throughput Sequencing and Genotyping Resource Access (X01) Apply for PAR 14 207 Funding Number: PAR 14 207 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Longitudinal Assessment of Post traumatic Syndromes (U01) Apply for RFA MH 15 110 Funding Number: RFA MH 15 110 Agency: National Institutes of Health Category: Health Funding Amount: $5,000,000 |
| Enhancing situational awareness, surveillance, detection, risk assessment and response activities using a mapping and visualization tool Apply for CDC RFA CK14 1404 Funding Number: CDC RFA CK14 1404 Agency: Centers for Disease Control and Prevention Category: Health Funding Amount: $1,000,000 |
| NINDS Renewal Awards of SBIR Phase II Grants (Phase IIB) for Pre Clinical Research (R44) Apply for PAR 14 209 Funding Number: PAR 14 209 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| NINDS Renewal Awards of SBIR Phase II Grants (Phase IIB) for Exploratory Clinical Trials and Clinical Research (R44) Apply for PAR 14 208 Funding Number: PAR 14 208 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Affordable Care Act SHIP and ADRC Options Counseling for Medicare Medicaid Individuals in States with Approved Financial Alignment Models Apply for CMS 1N1 14 001 Funding Number: CMS 1N1 14 001 Agency: Centers for Medicare Medicaid Services Category: Health Funding Amount: $1,000,000 |
| Pharmacogenomics Knowledge Base (R24) Apply for RFA GM 15 002 Funding Number: RFA GM 15 002 Agency: National Institutes of Health Category: Health Funding Amount: $1,600,000 |
Grant application guides and resources
It is always free to apply for government grants. However the process may be very complex depending on the funding opportunity you are applying for. Let us help you!
Apply for Grants
Premium leads for funding administrators, grant writers, and loan issuers
Thousands of people visit our website for their funding needs every day. When a user creates a grant proposal and files for submission, we pass the information on to funding administrators, grant writers, and government loan issuers.
If you manage government grant programs, provide grant writing services, or issue personal or government loans, we can help you reach your audience.
Subscribe to Leads
Request more information:
Would you like to learn more about this funding opportunity, similar opportunities to "PA 14 196", eligibility, application service, and/or application tips? Submit an inquiry below:
Don't forget to subscribe to our grant alerts mailing list to receive weekly alerts on new and updated grant funding opportunities like this one in your email.