Opportunity Information: Apply for PA 14 197

  • The National Institutes of Health in the health sector is offering a public funding opportunity titled "Complex Technologies and Therapeutics Development for Mental Health Research and Practice (R43/R44)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.242 Mental Health Research Grants.
  • This funding opportunity was created on Apr 30, 2014 and posted on Apr 30, 2014.
  • Applicants must submit their applications by May 7, 2017. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Eligible applicants include: Small businesses.
  • Other Eligible Applicants include the following Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, may be allowed.
Apply for PA 14 197

[Watch] Creating a grant proposal using the step-by-step wizard inside the applicant portal:

Opportunity Summary:

The funding opportunity titled "Complex Technologies and Therapeutics Development for Mental Health Research and Practice (R43/R44)" is a National Institutes of Health (NIH) Small Business Innovation Research (SBIR) grant announcement issued by the National Institute of Mental Health (NIMH). Its central purpose is to help small businesses research and develop advanced technologies and therapeutics that can directly support NIMH's mission across the mental health pipeline, from early-stage neuroscience through real-world clinical care. What makes this particular opportunity distinct is its emphasis on "complex" projects that need larger budgets and longer timelines than what is typically allowed under standard SBIR rules, which is often the case for sophisticated technology development, integrated platforms, or therapeutics that require more extensive engineering, testing, and validation.

In practical terms, the announcement invites small businesses to propose work that advances mental health research and practice in several key areas. This includes basic neuroscience research that is relevant to mental disorders (for example, tools that help measure brain function or behavior in ways that illuminate mechanisms of illness), translational and clinical research (such as technologies that can bridge lab findings to patient studies), and improvements in clinical diagnosis or treatment (including software, devices, digital platforms, or therapeutic development efforts that could lead to better outcomes). It also explicitly recognizes the importance of dissemination of evidence-based mental health care, meaning projects that help deliver proven interventions more effectively in real-world settings can fit the goals, especially when they rely on advanced, resource-intensive technology development.

The mechanism used is the SBIR R43/R44 pathway, which generally corresponds to phased small business R and D funding (commonly aligned with feasibility and development stages). The Funding Opportunity Number is PA-14-197, and it falls under the discretionary grant category with a health-related funding activity classification. The associated CFDA number listed is 93.242 (Mental Health Research Grants). There is no cost sharing or matching requirement, which means applicants are not required to contribute non-federal matching funds as a condition of the award.

Eligibility is limited to small businesses, consistent with SBIR program rules. Foreign institutions and non-U.S. entities are not eligible to apply, and non-U.S. components of U.S. organizations are also not eligible. However, the announcement notes that foreign components, as defined in the NIH Grants Policy Statement, may be allowed in some cases, which typically means limited, well-justified parts of the project may be performed outside the U.S. if they are essential and meet NIH policy requirements. This kind of allowance is narrower than full foreign eligibility and usually requires clear justification in the application.

The opportunity was posted and created on April 30, 2014. The original closing date and the current closing date are both listed as May 7, 2017, and the archive date is June 7, 2017, indicating the announcement is no longer active for new submissions under that specific posting. For applicants or researchers looking for the full historical announcement language and details, NIH provided an official link to the funding announcement page at http://grants.nih.gov/grants/guide/pa-files/PA-14-197.html. For access or technical issues, the contact provided is the NIH Office of Extramural Research (OER) webmaster via FBOWebmaster@OD.NIH.GOV, which reflects support for problems retrieving or linking to the announcement rather than scientific or programmatic questions.

Overall, this FOA was designed to push beyond routine SBIR-scale projects by supporting small business-driven development of high-impact, technically demanding mental health technologies and therapeutics, with the explicit aim of improving what researchers can study, what clinicians can diagnose and treat, and how evidence-based care can be delivered at scale.

Frequently Asked Questions (FAQs)

What is the title of this funding opportunity?

The opportunity is titled "Complex Technologies and Therapeutics Development for Mental Health Research and Practice (R43/R44)."

Which agency and institute issued this opportunity?

It is a National Institutes of Health (NIH) Small Business Innovation Research (SBIR) funding announcement issued by the National Institute of Mental Health (NIMH).

What is the main purpose of this FOA?

The central purpose is to help small businesses research and develop advanced technologies and therapeutics that directly support NIMH's mission across the mental health pipeline, ranging from early-stage neuroscience through real-world clinical care.

What makes this SBIR opportunity different from standard SBIR announcements?

This FOA emphasizes "complex" projects that require larger budgets and longer timelines than what is typically allowed under standard SBIR rules. It is intended for sophisticated technology development, integrated platforms, or therapeutics requiring more extensive engineering, testing, and validation.

What types of projects does the FOA encourage?

The FOA invites small businesses to propose work that advances mental health research and practice, including: basic neuroscience research relevant to mental disorders; translational and clinical research; improvements in clinical diagnosis or treatment; and efforts that support dissemination of evidence-based mental health care, particularly when advanced, resource-intensive technology development is needed.

Does the FOA support basic neuroscience research tools?

Yes. It includes basic neuroscience research relevant to mental disorders, such as tools that measure brain function or behavior in ways that help illuminate mechanisms of illness.

Does the FOA support translational and clinical research technologies?

Yes. It includes translational and clinical research, including technologies that bridge laboratory findings to patient studies.

Does the FOA support clinical diagnosis or treatment improvements?

Yes. It explicitly includes improvements in clinical diagnosis or treatment, including software, devices, digital platforms, or therapeutic development efforts that could lead to better outcomes.

Does the FOA support dissemination of evidence-based mental health care?

Yes. The FOA recognizes the importance of disseminating evidence-based mental health care, including projects that help deliver proven interventions more effectively in real-world settings, especially when they depend on complex technology development.

What funding mechanism is used?

The mechanism is the SBIR R43/R44 pathway, which generally corresponds to phased small business research and development funding commonly aligned with feasibility and development stages.

What is the Funding Opportunity Number (FOA number)?

The Funding Opportunity Number is PA-14-197.

What is the CFDA number associated with this opportunity?

The CFDA number listed is 93.242 (Mental Health Research Grants).

What type of grant category is this?

It is listed under the discretionary grant category and has a health-related funding activity classification.

Is cost sharing or matching required?

No. There is no cost sharing or matching requirement, meaning applicants are not required to contribute non-federal matching funds as a condition of the award.

Who is eligible to apply?

Eligibility is limited to small businesses, consistent with SBIR program rules.

Are foreign institutions or non-U.S. entities eligible to apply?

No. Foreign institutions and non-U.S. entities are not eligible to apply under this announcement.

Are non-U.S. components of U.S. organizations eligible?

No. Non-U.S. components of U.S. organizations are not eligible.

Are any foreign activities allowed at all?

The FOA notes that foreign components, as defined in the NIH Grants Policy Statement, may be allowed in some cases. This generally means limited, well-justified parts of the project may be performed outside the U.S. when essential and consistent with NIH policy requirements.

When was this opportunity posted?

The opportunity was posted and created on April 30, 2014.

What were the closing dates for submission?

The original closing date and the current closing date are both listed as May 7, 2017.

Is this FOA still active?

No. The archive date is June 7, 2017, indicating the announcement is no longer active for new submissions under that specific posting.

Where can someone find the official NIH announcement page?

The official NIH link provided is http://grants.nih.gov/grants/guide/pa-files/PA-14-197.html.

Who should be contacted for access or technical issues with the announcement page?

For access or technical issues, the contact provided is the NIH Office of Extramural Research (OER) webmaster at FBOWebmaster@OD.NIH.GOV.

Is the listed contact intended for scientific or programmatic questions?

The provided contact is described as support for problems retrieving or linking to the announcement, rather than scientific or programmatic questions.

What overall goal is this FOA trying to achieve in mental health?

It aims to support small business-driven development of high-impact, technically demanding mental health technologies and therapeutics to improve what researchers can study, what clinicians can diagnose and treat, and how evidence-based care can be delivered at scale.

Browse more business programs for Mental Health Services

Browse more opportunities from the same agency: National Institutes of Health

Browse more opportunities from the same category: Health

Next opportunity: Wireless Innovation between Finland and the US

Previous opportunity: Complex Technologies and Therapeutics Development for Mental Health Research and Practice (R41/R42)

USGrants.org Applicant Portal:

Are you interested in learning about about how to apply for this government funding opportunity? You can create a free applicant account and receive instant access to our applicant portal that many business owners like you have benefited from.

Apply for PA 14 197

 

[Watch] how do funding administrators access proposals?

Applicants also applied for:

Applicants who have applied for this opportunity (PA 14 197) also looked into and applied for these:

Funding Opportunity
EPT 2, One Health Workforce Apply for RFA OAA 14 000023

Funding Number: RFA OAA 14 000023
Agency: Agency for International Development
Category: Health
Funding Amount: $50,000,000
American Indians Into Medicine Apply for HHS 2014 IHS INMED 0001

Funding Number: HHS 2014 IHS INMED 0001
Agency: Indian Health Service
Category: Health
Funding Amount: $195,000
Unconventional Roles of Ethanol Metabolizing Enzymes, Metabolites, and Cofactors in Health and Disease (R01) Apply for PA 14 198

Funding Number: PA 14 198
Agency: National Institutes of Health
Category: Health
Funding Amount: Case Dependent
NIAMS Clinical Trial Implementation Cooperative Agreement (U01) Apply for PAR 14 200

Funding Number: PAR 14 200
Agency: National Institutes of Health
Category: Health
Funding Amount: Case Dependent
NIAMS Clinical Trial Planning Cooperative Agreement (U34) Apply for PAR 14 199

Funding Number: PAR 14 199
Agency: National Institutes of Health
Category: Health
Funding Amount: $250,000
Sudden Death in the Young (SDY) Registry Apply for CDC RFA DP14 1403

Funding Number: CDC RFA DP14 1403
Agency: NCCDPHP
Category: Health
Funding Amount: $200,000
NEI Administrative Supplements to Small Business Innovative Research (SBIR) Grants for the Procurement of Expertise in the Federal Regulatory Approval Process for New Drugs and/or Devices (Admin Supp) Apply for PA 14 205

Funding Number: PA 14 205
Agency: National Institutes of Health
Category: Health
Funding Amount: Case Dependent
Strengthening a network of immunization programs to support the NCIRD mission to prevent disease through immunization Apply for CDC RFA IP14 1402

Funding Number: CDC RFA IP14 1402
Agency: Centers for Disease Control and Prevention
Category: Health
Funding Amount: $700,000
Enhancing Cancer Registries for Early Case Capture (ECC) of Pediatric and Young Adult Cancer (PYAC) Cases Apply for CDC RFA DP14 1402

Funding Number: CDC RFA DP14 1402
Agency: Centers for Disease Control and Prevention
Category: Health
Funding Amount: Case Dependent
Enhancing Cancer Genomic Best Practices through Education, Surveillance, and Policy Apply for CDC RFA DP14 1407

Funding Number: CDC RFA DP14 1407
Agency: Centers for Disease Control and Prevention
Category: Health
Funding Amount: $350,000
HIV Vaccine Research and Design (HIVRAD) Program (P01) Apply for PAR 14 206

Funding Number: PAR 14 206
Agency: National Institutes of Health
Category: Health
Funding Amount: Case Dependent
Protecting and Improving Public Health Globally Building and Strengthening Public Health Impact, Systems, Capacity and Security Apply for CDC RFA GH14 1418

Funding Number: CDC RFA GH14 1418
Agency: Centers for Disease Control and Prevention
Category: Health
Funding Amount: Case Dependent
Center for Inherited Disease Research (CIDR) High Throughput Sequencing and Genotyping Resource Access (X01) Apply for PAR 14 207

Funding Number: PAR 14 207
Agency: National Institutes of Health
Category: Health
Funding Amount: Case Dependent
Longitudinal Assessment of Post traumatic Syndromes (U01) Apply for RFA MH 15 110

Funding Number: RFA MH 15 110
Agency: National Institutes of Health
Category: Health
Funding Amount: $5,000,000
Enhancing situational awareness, surveillance, detection, risk assessment and response activities using a mapping and visualization tool Apply for CDC RFA CK14 1404

Funding Number: CDC RFA CK14 1404
Agency: Centers for Disease Control and Prevention
Category: Health
Funding Amount: $1,000,000
NINDS Renewal Awards of SBIR Phase II Grants (Phase IIB) for Pre Clinical Research (R44) Apply for PAR 14 209

Funding Number: PAR 14 209
Agency: National Institutes of Health
Category: Health
Funding Amount: Case Dependent
NINDS Renewal Awards of SBIR Phase II Grants (Phase IIB) for Exploratory Clinical Trials and Clinical Research (R44) Apply for PAR 14 208

Funding Number: PAR 14 208
Agency: National Institutes of Health
Category: Health
Funding Amount: Case Dependent
Affordable Care Act SHIP and ADRC Options Counseling for Medicare Medicaid Individuals in States with Approved Financial Alignment Models Apply for CMS 1N1 14 001

Funding Number: CMS 1N1 14 001
Agency: Centers for Medicare Medicaid Services
Category: Health
Funding Amount: $1,000,000
Pharmacogenomics Knowledge Base (R24) Apply for RFA GM 15 002

Funding Number: RFA GM 15 002
Agency: National Institutes of Health
Category: Health
Funding Amount: $1,600,000
Local Nongovernmental Partnerships for Sustained Country Leadership in Rwanda under the Presidents Emergency Plan for AIDS Relief (PEPFAR) Apply for CDC RFA GH14 1414

Funding Number: CDC RFA GH14 1414
Agency: Centers for Disease Control and Prevention
Category: Health
Funding Amount: Case Dependent

 

Grant application guides and resources

It is always free to apply for government grants. However the process may be very complex depending on the funding opportunity you are applying for. Let us help you!

Apply for Grants

 

USGrants.org applicant portal membership

 

Premium leads for funding administrators, grant writers, and loan issuers

Thousands of people visit our website for their funding needs every day. When a user creates a grant proposal and files for submission, we pass the information on to funding administrators, grant writers, and government loan issuers.

If you manage government grant programs, provide grant writing services, or issue personal or government loans, we can help you reach your audience.

Subscribe to Leads

 

Request more information:

Would you like to learn more about this funding opportunity, similar opportunities to "PA 14 197", eligibility, application service, and/or application tips? Submit an inquiry below:

Don't forget to subscribe to our grant alerts mailing list to receive weekly alerts on new and updated grant funding opportunities like this one in your email.