Opportunity Information: Apply for CDC RFA GH12 1252

  • The Centers for Disease Control and Prevention in the health sector is offering a public funding opportunity titled "Construction of a Regional Reference Laboratory in Leribe" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.067 Global AIDS.
  • This funding opportunity was created on Mar 30, 2012 and posted on Mar 23, 2012.
  • Applicants must submit their applications by May 16, 2012. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $3,000,000.00 to eligible and selected applicants.
  • Each selected applicant is eligible to receive up to $1,000,000.00 in funding.
  • The number of recipients for this funding is limited to 1 candidate(s).
  • Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
  • The only eligible applicant that can apply for this funding opportunity is the Ministry of Health and Social Welfare (MOHSW). The MOHSW is the governmental agency responsible for safeguarding public health in Lesotho. The MOHSW has been mandated by the Government of the Kingdom of Lesotho (GOL) with the responsibility for maintaining a national laboratory system and providing decentralized and integrated laboratory services throughout the country. This responsibility is carried out by the Directorate of Laboratory services of the MOHSW.
Apply for CDC RFA GH12 1252

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Opportunity Summary:

The grant opportunity titled "Construction of a Regional Reference Laboratory in Leribe" (Funding Opportunity Number CDC RFA GH12-1252) is a U.S. Centers for Disease Control and Prevention (CDC) cooperative agreement focused on strengthening public health laboratory infrastructure in Lesotho under the President's Emergency Plan for AIDS Relief (PEPFAR). The project centers on building a new Regional Reference Laboratory adjacent to Motebang Hospital in Leribe. The overall purpose is to expand access to reliable, quality-assured diagnostic testing and patient monitoring services, especially in response to growing needs linked to HIV and tuberculosis.

A key driver behind the award is that demand for laboratory testing has reportedly doubled in recent years. This increase is tied to multiple overlapping pressures: the high burden of HIV/TB co-epidemics, the expansion of antiretroviral therapy (ART) services (which raises the need for routine patient monitoring tests), and the growing necessity for more advanced tuberculosis diagnostics such as culture and drug susceptibility testing (DST). In practical terms, the opportunity is designed to relieve bottlenecks in testing capacity and help the health system keep up with the clinical and public health requirements of a larger treated population and more complex TB case management.

The proposed regional laboratory is intended to provide a safer and more appropriate working environment for laboratory staff while also increasing both the volume and sophistication of testing that can be performed. Beyond general diagnostic services, the laboratory is expected to expand into specialty testing areas that are particularly important for HIV and TB programs. The announcement specifically highlights microbial and TB culture, DST, patient monitoring services, and specialized molecular testing, including early infant diagnosis (EID) and HIV viral load assays. These services are central to identifying HIV infection in newborns as early as possible, monitoring whether ART is effectively suppressing the virus, and detecting drug-resistant TB so patients can be placed on the right treatment regimen.

Another important aspect of the opportunity is the role the facility will play as a regional reference testing center for Leribe and surrounding districts. Rather than serving only a single hospital, the laboratory is positioned as a hub that can support multiple districts by receiving referrals, standardizing methods, and improving overall quality of testing services. In addition to routine service delivery, the laboratory is also expected to support operational research and trainings, which points to a broader system-building aim: strengthening workforce skills, improving procedures and quality management practices, and generating evidence to improve program performance and patient outcomes.

From an administrative standpoint, the opportunity falls under the Health funding activity category and uses a cooperative agreement mechanism, which typically means the CDC anticipates having substantial programmatic involvement during implementation compared with a standard grant. The estimated total funding listed is $3,000,000, with an award ceiling of $1,000,000, and the expected number of awards is one. The CFDA number is 93.067 (Global AIDS). There is no cost sharing or matching requirement, lowering the financial burden on the recipient for required counterpart funding.

Eligibility for this funding opportunity is highly restricted. The only eligible applicant is the Lesotho Ministry of Health and Social Welfare (MOHSW), identified as the government agency responsible for safeguarding public health and maintaining the national laboratory system. The announcement frames this as part of MOHSW's mandate from the Government of the Kingdom of Lesotho, carried out through the Directorate of Laboratory Services. In other words, this is not an open competition for NGOs or universities; it is structured as a direct investment into government-led laboratory system development.

The opportunity was posted on March 23, 2012, with a creation date of March 30, 2012. The original closing date was May 21, 2012, later adjusted to May 16, 2012, and the archive date is June 20, 2012. For access issues related to the full announcement, the listed contact is the CDC Procurement and Grants Office (PGO) via pgotim@cdc.gov and phone 770-488-2700.

Frequently Asked Questions (FAQs)

What is the title of this grant opportunity?

The opportunity is titled "Construction of a Regional Reference Laboratory in Leribe."

What is the Funding Opportunity Number?

The Funding Opportunity Number is CDC RFA GH12-1252.

Which U.S. agency is offering this opportunity?

This is a U.S. Centers for Disease Control and Prevention (CDC) opportunity.

What type of award is this?

The award mechanism is a cooperative agreement. This typically indicates CDC expects substantial programmatic involvement during implementation compared with a standard grant.

What is the main purpose of the project?

The overall purpose is to strengthen public health laboratory infrastructure in Lesotho by expanding access to reliable, quality-assured diagnostic testing and patient monitoring services, with particular emphasis on needs tied to HIV and tuberculosis.

How does this opportunity relate to PEPFAR?

The project is described as part of the President's Emergency Plan for AIDS Relief (PEPFAR), focused on supporting HIV-related and associated laboratory services, including key testing used for HIV and TB programs.

What will be built under this opportunity?

The project centers on building a new Regional Reference Laboratory.

Where will the new laboratory be located?

The laboratory is intended to be constructed adjacent to Motebang Hospital in Leribe, Lesotho.

Why is a new regional reference laboratory needed?

The announcement cites a reported doubling of demand for laboratory testing in recent years. This increase is linked to the high burden of HIV/TB co-epidemics, expansion of antiretroviral therapy (ART) services (which increases routine patient monitoring testing needs), and the growing need for more advanced TB diagnostics such as culture and drug susceptibility testing (DST).

What problem is the project intended to solve?

It is intended to relieve bottlenecks in testing capacity and help the health system keep pace with clinical and public health requirements created by a larger treated population and more complex TB case management needs.

What is meant by "regional reference" in this opportunity?

The laboratory is positioned as a regional reference testing center for Leribe and surrounding districts, acting as a hub to receive referred specimens/testing needs, standardize methods, and improve overall quality of testing services beyond a single hospital.

What types of testing and services are highlighted for the laboratory?

The announcement highlights expanded diagnostic and specialty services including microbial and TB culture, drug susceptibility testing (DST), patient monitoring services, and specialized molecular testing.

What molecular testing is specifically mentioned?

Specialized molecular testing mentioned includes early infant diagnosis (EID) and HIV viral load assays.

How do early infant diagnosis (EID) and HIV viral load testing support HIV programs?

EID supports identifying HIV infection in newborns as early as possible. HIV viral load assays support monitoring whether antiretroviral therapy (ART) is effectively suppressing the virus.

How does TB culture and DST support tuberculosis programs?

TB culture and drug susceptibility testing (DST) support detection of drug-resistant TB so patients can be placed on the appropriate treatment regimen.

Will the new facility address laboratory staff working conditions?

Yes. The laboratory is described as providing a safer and more appropriate working environment for laboratory staff while also increasing the volume and sophistication of testing that can be performed.

Does the opportunity mention training or research activities?

Yes. In addition to routine service delivery, the laboratory is expected to support operational research and trainings, aligning with broader system-building goals such as strengthening workforce skills, improving procedures and quality management practices, and generating evidence to improve program performance and patient outcomes.

What funding activity category does this opportunity fall under?

The opportunity falls under the Health funding activity category.

What is the CFDA number for this opportunity?

The CFDA number is 93.067 (Global AIDS).

How much funding is available?

The estimated total funding listed is $3,000,000.

What is the award ceiling?

The award ceiling is $1,000,000.

How many awards does CDC expect to make?

The expected number of awards is one.

Is cost sharing or matching required?

No. The opportunity states there is no cost sharing or matching requirement.

Who is eligible to apply?

Eligibility is highly restricted. The only eligible applicant is the Lesotho Ministry of Health and Social Welfare (MOHSW).

Are NGOs, universities, or other organizations eligible to apply?

No. The opportunity is not an open competition; it is structured as a direct investment into government-led laboratory system development, with MOHSW as the only eligible applicant.

Why is MOHSW the only eligible applicant?

The announcement identifies MOHSW as the government agency responsible for safeguarding public health and maintaining the national laboratory system, acting through the Directorate of Laboratory Services as part of its mandate from the Government of the Kingdom of Lesotho.

When was the opportunity posted?

The opportunity was posted on March 23, 2012.

What is the creation date listed for the opportunity?

The creation date is March 30, 2012.

What was the application closing date?

The original closing date was May 21, 2012, and it was later adjusted to May 16, 2012.

When was the opportunity archived?

The archive date is June 20, 2012.

Who should be contacted for access issues related to the full announcement?

For access issues, the listed contact is the CDC Procurement and Grants Office (PGO).

What are the contact details for the CDC Procurement and Grants Office (PGO)?

Email: pgotim@cdc.gov
Phone: 770-488-2700

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