Opportunity Information: Apply for RFA HD 12 185
Apply for RFA HD 12 185
- The National Institutes of Health in the health income security and social services sector is offering a public funding opportunity titled "Contraceptive Development Research Centers Program (U54)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.865 Child Health and Human Development Extramural Research.
- This funding opportunity was created on May 23, 2011 and posted on May 23, 2011.
- Applicants must submit their applications by Nov 29, 2011. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $6,600,000.00 to eligible and selected applicants.
- Eligible applicants include: County governments Private institutions of higher education Public and State controlled institutions of higher education City or township governments Native American tribal governments (Federally recognized) Independent school districts Others (see text field entitled Additional Information on Eligibility for clarification) Public housing authorities/Indian housing authorities State governments Special district governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Organizations) are not eligible to apply. Foreign (non U.S.) components of U.S. Organizations are not allowed.
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Opportunity Summary:
The Contraceptive Development Research Centers Program (U54) is a National Institutes of Health (NIH) cooperative agreement funding opportunity that supports multidisciplinary research centers focused on discovering, developing, and advancing new contraceptive products toward clinical usefulness. The program is a re-competition of an existing center initiative, meaning NIH is continuing and refreshing a national network of centers that can carry out both basic and applied research tied to real-world product development. The central expectation is high-quality translational work: centers are meant to bridge early-stage scientific discoveries with the practical steps needed to move promising contraceptive candidates closer to clinical evaluation and eventual use.
A defining feature of this opportunity is its center-based structure and broad scientific scope. Rather than funding a single narrow project, the U54 mechanism is designed to support coordinated, team-driven programs that combine multiple disciplines and capabilities under one umbrella. The funded centers are intended to run integrated research portfolios spanning contraceptive product discovery and development, leveraging expertise that may include reproductive biology, pharmacology, medicinal chemistry, biomaterials and drug delivery, clinical research planning, and other relevant fields. The goal is to create an environment where ideas can be tested, refined, and advanced efficiently, with a strong emphasis on moving beyond purely descriptive science toward development-oriented milestones.
The program also explicitly positions the funded centers as a national resource for career development. In addition to producing research outputs, centers are expected to help train and mentor early-career scientists who want to build careers in contraceptive research and development. This reflects a workforce-building purpose: NIH is not only supporting the science itself, but also strengthening the pipeline of investigators capable of sustaining contraceptive development efforts over the long term.
Administratively, this opportunity is a discretionary grant in the form of a cooperative agreement, which generally signals substantial scientific or programmatic involvement by the NIH compared with a standard research project grant. The funding opportunity number is RFA-HD-12-185 (listed as RFA HD 12 185), and it falls under the activity category of Health, Income Security, and Social Services, with CFDA number 93.865 (Child Health and Human Development Extramural Research). The posting and creation dates were May 23, 2011, with an original and current closing date of November 29, 2011, and an archive date of December 30, 2011. The estimated total funding level is listed as $6,600,000, indicating NIH anticipated supporting a set of center awards under this announcement within that overall amount.
Eligibility is broad across U.S.-based organizations and governments, reflecting the center model and the desire to draw from many sectors with relevant expertise and infrastructure. Eligible applicants include public and private institutions of higher education, nonprofits (including both 501(c)(3) and certain non-501(c)(3) organizations other than institutions of higher education), for-profit organizations other than small businesses, small businesses, and a range of governmental entities (state, county, city or township, special district governments, and independent school districts). Tribal governments and tribal organizations are also included, as are public housing authorities/Indian housing authorities. The eligibility language also calls out additional eligible applicants such as Alaska Native and Native Hawaiian Serving Institutions, Hispanic Serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, regional organizations, eligible federal agencies, and U.S. territories or possessions. At the same time, the FOA makes a clear boundary around foreign participation: non-U.S. entities are not eligible to apply, and foreign components of U.S. organizations are not allowed, meaning the work must be organized and carried out without foreign organizational components under this announcement.
There is no cost sharing or matching requirement, which simplifies budgeting and lowers barriers for applicants by not requiring them to provide non-federal matching funds as a condition of award. For applicants or interested parties seeking the official full announcement and detailed requirements, NIH provided an additional information link to the FOA on the NIH grants guide website (http://grants.nih.gov/grants/guide/rfa-files/RFA-HD-12-185.html). For access issues or technical problems with the announcement link, the contact route provided is the NIH Office of Extramural Research (OER) webmaster at FBOWebmaster@OD.NIH.GOV.
Overall, the opportunity is aimed at building and sustaining a small national set of high-capacity research centers that can collectively push contraceptive science forward in a development-minded way, while also training the next generation of scientists in a field that depends heavily on long-term, cross-disciplinary collaboration and a clear path from laboratory findings to products that can be used in clinical settings.
Frequently Asked Questions (FAQs)
What is the Contraceptive Development Research Centers Program (U54)?
The Contraceptive Development Research Centers Program (U54) is an NIH cooperative agreement funding opportunity that supports multidisciplinary research centers focused on discovering, developing, and advancing new contraceptive products toward clinical usefulness.
What is the main purpose of this funding opportunity?
The main purpose is to support center-based, team-driven research programs that move contraceptive candidates from early scientific discovery toward practical development steps that bring them closer to clinical evaluation and eventual use.
What does "translational" mean in the context of this program?
In this program, "translational" refers to research that bridges early-stage scientific discoveries with development-oriented work, emphasizing practical milestones that help advance promising contraceptive candidates toward clinical usefulness rather than stopping at purely descriptive science.
Is this opportunity for a single research project or a coordinated center program?
This opportunity is designed for coordinated research centers, not a single narrow project. The U54 mechanism supports integrated portfolios of work under one umbrella, combining multiple disciplines and capabilities.
What kinds of scientific disciplines or capabilities are relevant for a U54 center under this program?
The announcement describes a broad scope and indicates centers may leverage expertise such as reproductive biology, pharmacology, medicinal chemistry, biomaterials and drug delivery, and clinical research planning, along with other fields relevant to contraceptive product discovery and development.
What types of research are centers expected to conduct?
Funded centers are expected to run integrated research portfolios spanning contraceptive product discovery and development, with an emphasis on advancing candidates efficiently and aligning research efforts with real-world product development needs.
How is this program described in terms of continuity with prior NIH efforts?
The program is described as a re-competition of an existing center initiative, meaning NIH is continuing and refreshing a national network of centers that can carry out both basic and applied research tied to product development.
Does the program include training or career development expectations?
Yes. A defining expectation is that funded centers serve as a national resource for career development by training and mentoring early-career scientists interested in contraceptive research and development, helping strengthen the long-term investigator pipeline.
What type of award mechanism is used for this opportunity?
This is a discretionary grant awarded as an NIH cooperative agreement (U54). A cooperative agreement generally indicates substantial scientific or programmatic involvement by NIH compared with a standard research project grant.
What is the funding opportunity number for this announcement?
The funding opportunity number is RFA-HD-12-185 (also listed as RFA HD 12 185).
What is the CFDA number associated with this opportunity?
The CFDA number listed is 93.865, identified as Child Health and Human Development Extramural Research.
What is the activity category for this opportunity?
The activity category is listed as Health, Income Security, and Social Services.
What are the posting and closing dates shown for this opportunity?
The posting and creation dates are May 23, 2011. The original and current closing date is November 29, 2011. The archive date is December 30, 2011.
How much total funding was estimated under this announcement?
The estimated total funding level is listed as $6,600,000, reflecting NIH's anticipation of supporting a set of center awards under this announcement within that overall amount.
Who is eligible to apply?
Eligibility is broad across U.S.-based organizations and governments. Eligible applicants include public and private institutions of higher education; nonprofits (including 501(c)(3) and certain non-501(c)(3) organizations other than institutions of higher education); for-profit organizations other than small businesses; small businesses; and governmental entities such as state, county, city or township, special district governments, and independent school districts.
Are tribal entities eligible to apply?
Yes. Tribal governments and tribal organizations are included among eligible applicants.
Are public housing authorities eligible to apply?
Yes. Public housing authorities/Indian housing authorities are explicitly included in the eligibility description.
Are minority-serving institutions specifically mentioned as eligible?
Yes. The eligibility language calls out Alaska Native and Native Hawaiian Serving Institutions, Hispanic Serving Institutions, Historically Black Colleges and Universities (HBCUs), and Tribally Controlled Colleges and Universities (TCCUs) among additional eligible applicants.
Are faith-based or community-based organizations eligible?
Yes. Faith-based or community-based organizations are listed among additional eligible applicants.
Can federal agencies apply?
Yes. Eligible federal agencies are included among the additional eligible applicants mentioned.
Are U.S. territories or possessions eligible to apply?
Yes. U.S. territories or possessions are included among the additional eligible applicants.
Are non-U.S. (foreign) entities eligible to apply?
No. Non-U.S. entities are not eligible to apply under this announcement.
Are foreign components of U.S. organizations allowed?
No. Foreign components of U.S. organizations are not allowed, meaning work under this announcement must be organized and carried out without foreign organizational components.
Is cost sharing or matching required?
No. The announcement states there is no cost sharing or matching requirement.
Where can applicants find the full official announcement?
The full FOA is available on the NIH grants guide website at: http://grants.nih.gov/grants/guide/rfa-files/RFA-HD-12-185.html
Who should be contacted for technical issues accessing the FOA link?
For access issues or technical problems with the announcement link, the contact provided is the NIH Office of Extramural Research (OER) webmaster at FBOWebmaster@OD.NIH.GOV.
What is the overarching outcome NIH appears to be aiming for with this program?
The program aims to build and sustain a small national set of high-capacity research centers that can collectively advance contraceptive science in a development-minded way, while also training the next generation of scientists to support long-term progress in contraceptive research and development.
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