Opportunity Information: Apply for RFA ES 09 010
Apply for RFA ES 09 010
- The National Institutes of Health in the education environment health sector is offering a public funding opportunity titled "Coordinating Center for the Breast Cancer and the Environment Research Program (U01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113 Environmental Health 93.393 Cancer Cause and Prevention Research 93.396 Cancer Biology Research 93.399 Cancer Control.
- This funding opportunity was created on Oct 23, 2009 and posted on Oct 23, 2009.
- Applicants must submit their applications by Dec 30, 2009. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $900,000.00 to eligible and selected applicants.
- Each selected applicant is eligible to receive up to $600,000.00 in funding.
- Eligible applicants include: Small businesses Private institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Native American tribal governments (Federally recognized) Others (see text field entitled Additional Information on Eligibility for clarification) Public and State controlled institutions of higher education.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:
The Coordinating Center for the Breast Cancer and the Environment Research Program (BCERP) (Funding Opportunity Number RFA-ES-09-010) is a National Institutes of Health cooperative agreement (U01) sponsored by the National Institute of Environmental Health Sciences (NIEHS) in partnership with the National Cancer Institute (NCI). The grant is designed to fund an institution that will serve as the central hub for coordination, data stewardship, communication, and reporting across the broader BCERP research network. Rather than funding a stand-alone research study, this opportunity supports the infrastructure and leadership needed to keep multiple BCERP research sites aligned, interoperable, and productive as a single program.
At the core of the award is the requirement to operate as a central repository and clearinghouse for cross-site data, particularly data coming from an ongoing study focused on environmental influences on puberty in young girls. This means the Coordinating Center is expected to receive, organize, curate, and manage data contributed by participating sites so that the program can generate consistent, comparable analyses across locations. In practice, that typically involves establishing common data standards, data dictionaries, secure transfer and storage methods, quality control procedures, documentation, and processes for timely data sharing among authorized investigators and NIH program staff. The intent is to make cross-site integration feasible and reliable, so the program can answer larger questions than any one site could address alone.
A second major responsibility is program operations and communications. The Coordinating Center is expected to organize annual meetings and maintain a cadence of regular conference calls for the BCERP Steering Committee, its subcommittees, BCERP-supported investigators, and the public as appropriate. This function goes beyond scheduling. It implies agenda development in partnership with leadership, preparation and distribution of materials, coordination of speakers and working sessions, note-taking and action-item tracking, and follow-through to ensure decisions made by the Steering Committee translate into concrete next steps across sites. Because BCERP includes multiple disciplines and stakeholder groups, the Coordinating Center is also positioned as the connective tissue that keeps conversations coherent and decisions documented.
The Coordinating Center is also tasked with facilitating the BCERP Steering Committee and the Breast Cancer and the Environment Working Group (BCE WG). Facilitation here generally means enabling collaboration: supporting working groups, helping harmonize protocols and measures, encouraging consistent approaches to exposure assessment and outcome measurement, and supporting communication between scientists, community partners, and NIH staff. The opportunity makes clear that NIH expects regular progress reports and updates as requested, so the Coordinating Center must be capable of tracking milestones, compiling program-level summaries, and communicating both accomplishments and challenges in a way that helps NIH oversee and guide the cooperative agreement.
This coordinating award is explicitly tied to and runs in parallel with two related BCERP funding announcements that support the program's scientific work: one focused on continuation of an epidemiological investigation on early environmental exposures and human puberty (RFA-ES-09-008, limited competition), and another supporting laboratory and/or epidemiological studies on environmental influences during windows of susceptibility in breast cancer risk (RFA-ES-09-009). The Coordinating Center is meant to support these research components by providing shared infrastructure, standardized processes, and a program-wide platform for collaboration. In other words, the scientific projects generate data and findings, while the Coordinating Center makes it possible to combine insights across sites, keep teams coordinated, and ensure the overall program moves in a unified direction.
BCERP itself is framed as a transdisciplinary NIH effort examining how chemical, physical, biological, and social environmental factors interact with genetic factors during key windows of susceptibility across the lifespan, with an emphasis on pathways relevant to breast cancer risk. The Coordinating Center is therefore expected to bring a mix of scientific understanding and administrative capability. The announcement highlights that this role requires a unique set of scientific and administrative skills, reflecting the need to understand complex, multi-site research well enough to support data harmonization and cross-cutting analyses while also managing meetings, communications, documentation, and reporting obligations typical of large consortia.
From an administrative perspective, the funding instrument is a cooperative agreement (U01), which typically indicates substantial NIH involvement in the direction and oversight of the program compared to a standard research project grant. Applicants should interpret that as an expectation of close collaboration with NIEHS and NCI program staff, responsiveness to steering committee priorities, and an ability to operate transparently across multiple institutions and stakeholder groups. The award does not require cost sharing or matching.
Key logistics included in the announcement are: the opportunity was posted October 23, 2009, with an original and current closing date of December 30, 2009, and an archive date of January 30, 2010. The estimated total funding is $900,000, with an award ceiling of $600,000. The CFDA numbers listed align the opportunity with environmental health and cancer research domains (93.113, 93.393, 93.396, 93.399). Eligibility is broad, spanning small businesses, private and public institutions of higher education, nonprofits (including 501(c)(3) and certain non-501(c)(3) organizations), tribal organizations and governments, and a range of mission-focused institutions and community-based entities, including HBCUs, Hispanic-serving institutions, tribally controlled colleges and universities, Alaska Native and Native Hawaiian-serving institutions, and U.S. territories or possessions.
In plain terms, this grant is aimed at identifying a capable organization to run the backbone of the BCERP consortium: managing and harmonizing multi-site data, running the meetings and communications that keep the program aligned, supporting the steering and working groups that guide scientific direction and stakeholder engagement, and providing the reporting and updates NIH needs to oversee a complex, transdisciplinary research program focused on environmental determinants of breast development and breast cancer risk.
Frequently Asked Questions (FAQs)
What is the funding opportunity number for this grant?
The funding opportunity number is RFA-ES-09-010.
What is the name of this grant opportunity?
This opportunity supports the Coordinating Center for the Breast Cancer and the Environment Research Program (BCERP).
Which agencies are sponsoring this opportunity?
It is sponsored by the National Institute of Environmental Health Sciences (NIEHS) in partnership with the National Cancer Institute (NCI), both within the National Institutes of Health (NIH).
What type of NIH funding mechanism is this?
This award uses a cooperative agreement mechanism (U01), which typically involves substantial NIH program involvement in the direction and oversight of the effort.
What is the main purpose of the Coordinating Center award?
The award is intended to fund an institution to serve as the central hub for coordination, data stewardship, communication, and reporting across the broader BCERP research network. It is designed to support program infrastructure and leadership rather than a stand-alone research study.
Is this grant meant to fund a single independent research project?
No. The opportunity supports the infrastructure and leadership needed to coordinate multiple BCERP research sites so they can operate as a unified program.
What does it mean to be the "central hub" for BCERP?
It means the Coordinating Center is expected to keep multiple research sites aligned and interoperable by managing cross-site data systems and standards, organizing communications and meetings, supporting governance groups, and producing program-level reporting for NIH oversight.
What are the core data responsibilities of the Coordinating Center?
The Coordinating Center is required to operate as a central repository and clearinghouse for cross-site data. This includes receiving, organizing, curating, and managing data contributed by participating sites so analyses can be consistent and comparable across locations.
What kinds of study data are specifically highlighted as needing cross-site management?
The opportunity specifically highlights data from an ongoing study focused on environmental influences on puberty in young girls as a key source of cross-site data to be received and stewarded by the Coordinating Center.
What activities are implied by "data stewardship" in this opportunity?
Based on the announcement, data stewardship typically includes establishing common data standards and data dictionaries, setting up secure transfer and storage methods, implementing quality control procedures, maintaining documentation, and enabling timely data sharing among authorized investigators and NIH program staff.
Why is cross-site data harmonization important for BCERP?
The intent is to make cross-site integration feasible and reliable so the program can generate consistent, comparable analyses and answer larger questions than any one site could address alone.
What operational and communications responsibilities does the Coordinating Center have?
The Coordinating Center is expected to organize annual meetings and maintain regular conference calls for the BCERP Steering Committee, subcommittees, BCERP-supported investigators, and the public as appropriate.
Does the Coordinating Center only schedule meetings, or does it do more?
It goes beyond scheduling. The role includes agenda development with leadership, preparation and distribution of meeting materials, coordination of speakers and working sessions, note-taking, action-item tracking, and follow-through to help ensure Steering Committee decisions translate into concrete next steps across sites.
Which groups is the Coordinating Center expected to facilitate?
The Coordinating Center is tasked with facilitating the BCERP Steering Committee and the Breast Cancer and the Environment Working Group (BCE WG).
What does "facilitation" mean in the context of the Steering Committee and Working Group?
Facilitation is described as enabling collaboration across the network, including supporting working groups, helping harmonize protocols and measures, encouraging consistent approaches to exposure assessment and outcome measurement, and supporting communication between scientists, community partners, and NIH staff.
What are the reporting expectations to NIH under this opportunity?
The opportunity indicates NIH expects regular progress reports and updates as requested. This implies the Coordinating Center must track milestones, compile program-level summaries, and communicate accomplishments and challenges in ways that support NIH oversight and guidance.
How does this Coordinating Center relate to other BCERP funding announcements?
This award runs in parallel with two related BCERP announcements that support the program's scientific work: RFA-ES-09-008 (continuation of an epidemiological investigation on early environmental exposures and human puberty; limited competition) and RFA-ES-09-009 (laboratory and/or epidemiological studies on environmental influences during windows of susceptibility in breast cancer risk). The Coordinating Center is intended to support these scientific components through shared infrastructure, standardized processes, and program-wide collaboration support.
What is BCERP studying overall?
BCERP is described as a transdisciplinary NIH effort examining how chemical, physical, biological, and social environmental factors interact with genetic factors during key windows of susceptibility across the lifespan, with emphasis on pathways relevant to breast cancer risk.
What kinds of capabilities does the Coordinating Center need to demonstrate?
The announcement emphasizes a blend of scientific understanding and administrative capability. The Center should be able to support complex, multi-site research through data harmonization and cross-cutting analyses while also handling consortium operations such as meetings, communications, documentation, and reporting.
What does the U01 cooperative agreement imply about NIH involvement?
It implies close collaboration with NIEHS and NCI program staff, responsiveness to Steering Committee priorities, and an ability to operate transparently across multiple institutions and stakeholder groups, with NIH having a more active role than in a standard research project grant.
Is cost sharing or matching required?
No. The announcement states that the award does not require cost sharing or matching.
When was this opportunity posted?
The opportunity was posted on October 23, 2009.
What is the application closing date?
The original and current closing date listed is December 30, 2009.
When was the opportunity archived?
The archive date listed is January 30, 2010.
How much total funding is estimated for this opportunity?
The estimated total funding is $900,000.
What is the award ceiling?
The award ceiling is $600,000.
Which CFDA numbers are associated with this opportunity?
The CFDA numbers listed are 93.113, 93.393, 93.396, and 93.399.
Who is eligible to apply?
Eligibility is described as broad and includes small businesses; private and public institutions of higher education; nonprofits (including 501(c)(3) and certain non-501(c)(3) organizations); tribal organizations and governments; and a range of mission-focused institutions and community-based entities, including HBCUs, Hispanic-serving institutions, tribally controlled colleges and universities, Alaska Native and Native Hawaiian-serving institutions, and U.S. territories or possessions.
What is the practical outcome NIH appears to be seeking from this award?
In practical terms, NIH is seeking a capable organization to run the backbone of the BCERP consortium: manage and harmonize multi-site data, coordinate meetings and communications, support steering and working groups, and provide the reporting and updates needed to oversee a complex transdisciplinary program.
Will the Coordinating Center interact with the public?
The opportunity notes that regular conference calls may include the public as appropriate, indicating some communications may extend beyond internal investigators and committees depending on program needs.
Browse more opportunities from the same category: Education Environment Health
Next opportunity: Limited Competition Continuation of Studies on Early Environmental Exposures and Human Puberty (U01)
Previous opportunity: Environmental Influences during Windows of Susceptibility in Breast Cancer Risk (U01)
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Applicants also applied for:
Applicants who have applied for this opportunity (RFA ES 09 010) also looked into and applied for these:
| Funding Opportunity |
|---|
| Limited Competition Continuation of Studies on Early Environmental Exposures and Human Puberty (U01) Apply for RFA ES 09 008 Funding Number: RFA ES 09 008 Agency: National Institutes of Health Category: Education Environment Health Funding Amount: $650,000 |
| Enabling Technologies in DNA Repair Research (R21) Apply for PAR 10 016 Funding Number: PAR 10 016 Agency: National Institutes of Health Category: Education Environment Health Funding Amount: $200,000 |
| Limited Competition for the Global Research Initiative Program, Basic/Biomedical Sciences (R01) Apply for PAR 10 278 Funding Number: PAR 10 278 Agency: National Institutes of Health Category: Education Environment Health Funding Amount: Case Dependent |
| Deepwater Horizon Disaster Research Consortia Health Impacts and Community Resiliency (U19) Apply for RFA ES 11 006 Funding Number: RFA ES 11 006 Agency: National Institutes of Health Category: Education Environment Health Funding Amount: $1,200,000 |
| Superfund Hazardous Substance Research and Training Program (P42) Apply for RFA ES 10 010 Funding Number: RFA ES 10 010 Agency: National Institutes of Health Category: Education Environment Health Funding Amount: Case Dependent |
| Innovative Bioavailability Assays to Assess the Effectiveness of Contaminated Sediment Remediation (R01) Apply for RFA ES 11 005 Funding Number: RFA ES 11 005 Agency: National Institutes of Health Category: Education Environment Health Funding Amount: $200,000 |
| Limited Competition Fogarty International Research Collaboration Basic Biomedical (FIRCA BB) Research Award (R03) Apply for PAR 11 037 Funding Number: PAR 11 037 Agency: National Institutes of Health Category: Education Environment Health Funding Amount: Case Dependent |
| Ruth L. Kirschstein National Research Service Awards (NRSA) for Individual Senior Fellows (Parent F33) Apply for PA 11 114 Funding Number: PA 11 114 Agency: National Institutes of Health Category: Education Environment Health Funding Amount: Case Dependent |
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