Creutzfeldt Jakob Disease (CJD) Increasing Educational Support for CJD Families and the Nation | Apply Online

Opportunity Summary:

This funding opportunity (CDC RFA CK10-1001) is a Centers for Disease Control and Prevention cooperative agreement focused on Creutzfeldt-Jakob Disease (CJD) and other human prion diseases, with an emphasis on strengthening support for affected families while also improving national surveillance. The core idea is to bridge practical, real-world needs that families face during suspected or confirmed prion disease cases with the public health need to track CJD trends, recognize emerging variants, and improve the evidence base needed for faster recognition and response. The announcement also notes alignment with the Healthy People 2010 focus area of Infectious Diseases, framing prion disease work as part of broader national infectious disease readiness even though prion diseases are distinct from typical bacterial or viral infections.

The program lays out four main goals. First, it aims to give family members of patients with suspected or diagnosed prion disease easy access to consultation from people who are experienced and knowledgeable about the practical issues surrounding CJD. In practice, this means helping families navigate the disease trajectory, communication with clinicians, handling of personal and medical decisions, and the complex logistical and emotional issues that can come with a rapidly progressive, fatal neurodegenerative condition. Second, the opportunity seeks to facilitate educational and mutually beneficial interaction between researchers and family members of CJD patients. That point is important because it suggests a two-way exchange: families gain clearer information and guidance, while researchers and surveillance programs gain insights, participation, case information, and stronger relationships that can improve the quality and completeness of public health data. Third, the program explicitly targets increased general awareness about CJD, implying public-facing education and outreach to raise understanding among communities and potentially among healthcare professionals as well. Fourth, it aims to increase the number of autopsies performed in suspected CJD cases, which is a major surveillance and diagnostic priority because definitive confirmation and prion typing often rely on postmortem evaluation, and improved autopsy rates directly strengthen national understanding of incidence, subtypes, and possible variant cases.

From an administrative standpoint, the funding instrument is a cooperative agreement, which typically means the CDC expects to have substantial involvement with the awardee compared to a standard grant. The activity category is Health, and the CFDA number listed is 93.283 (CDC Investigations and Technical Assistance). The CDC anticipated making one award, with an estimated total funding amount of $325,000. The award ceiling is listed as $65,000, and the award floor is $0, indicating the maximum amount per budget period or per award action as specified in the announcement data. There is no cost sharing or matching requirement, which lowers barriers for organizations that may not have large unrestricted funds to contribute.

The timeline in the source data shows the opportunity was posted on April 5, 2010, with an original and current closing date of June 4, 2010, and an archive date of July 4, 2010. A letter of intent deadline is shown (April 29, 2010 in one line and April 19, 2010 in another), while the application deadline is consistently June 4, 2010. For applicants, those dates signal a relatively short turnaround window and the likelihood that CDC wanted applicants ready to move quickly on established education, family support, and surveillance-support activities.

Eligibility is broad and includes many types of public and nonprofit entities. Eligible applicants include nonprofits with or without 501(c)(3) status (as long as they are not institutions of higher education in that nonprofit category), universities and colleges, community-based and faith-based organizations, federally or state recognized American Indian/Alaska Native tribal governments, tribally designated organizations, Urban Indian health organizations, tribal epidemiology centers, and state and local governments and their bona fide agents. The announcement also clarifies that political subdivisions of states may apply in consultation with states. For entities applying as a bona fide agent on behalf of a state or local government, documentation is required: a letter from the state or local government confirming bona fide agent status must be attached in the application package (uploaded with the other attachment forms through Grants.gov). This wide eligibility pool suggests CDC was open to partnering with organizations that already have direct relationships with affected families, clinical and research networks, or established public health education capacity.

The practical impact of the work CDC is trying to fund can be summarized as a combined family-support and surveillance-strengthening initiative. By improving access to knowledgeable consultation and creating structured ways for families and researchers to interact, the program aims to reduce confusion and isolation for families while also making surveillance more complete and scientifically useful. Increasing public awareness can help with earlier recognition of symptoms and more informed engagement with healthcare systems. Finally, boosting autopsy rates directly improves diagnostic certainty and the ability to detect emerging prion disease variants, which is central to national situational awareness.

For questions or technical issues accessing the full announcement, the listed contact is the CDC Procurement and Grants Office TIMS, with phone number 770-488-2700 and email PGOTIM@cdc.gov.

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