Opportunity Information: Apply for RFA DK 11 004

  • The National Institutes of Health in the food and nutrition health sector is offering a public funding opportunity titled "Cystic Fibrosis Research and Translation Core Centers (P30)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research.
  • This funding opportunity was created on Apr 1, 2011 and posted on Apr 1, 2011.
  • Applicants must submit their applications by Jun 30, 2011. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $2,000,000.00 to eligible and selected applicants.
  • Each selected applicant is eligible to receive up to $750,000.00 in funding.
  • The number of recipients for this funding is limited to 2 candidate(s).
  • Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification) Special district governments Native American tribal governments (Federally recognized) Independent school districts Public and State controlled institutions of higher education County governments Native American tribal organizations (other than Federally recognized tribal governments) For profit organizations other than small businesses Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses Private institutions of higher education Public housing authorities/Indian housing authorities State governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education City or township governments.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:

The Cystic Fibrosis Research and Translation Core Centers (P30) funding opportunity (RFA-DK-11-004) is a National Institutes of Health (NIH) grant program administered through the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). It solicits both new applications and renewal applications to support specialized “core center” infrastructure focused on cystic fibrosis (CF). The central purpose is to strengthen and accelerate CF research by providing shared resources, services, and programs that individual labs or standalone projects typically cannot support as efficiently on their own, while also knitting together collaborations among investigators who already have a strong track record in CF research.

Programmatically, these P30 centers are built to serve both basic science and clinical/translational research needs in cystic fibrosis, with an emphasis on enabling the development and testing of new therapies. Rather than funding a single research project, the P30 mechanism is designed to fund a coordinated center framework that multiple investigators can use. The FOA highlights three main activity areas supported by the center: (1) Research Core services, which are shared core facilities or service units that provide specialized capabilities to CF investigators; (2) a Pilot and Feasibility (P&F) program, which typically supports smaller, early-stage, or high-impact studies to generate preliminary data, encourage innovation, and help investigators launch new lines of CF research; and (3) an Enrichment program, which is generally aimed at building the scientific community and strengthening the research environment through activities such as seminars, visiting speakers, workshops, training opportunities, and other efforts that promote collaboration and scientific exchange. Taken together, these components are meant to expand institutional capacity, improve efficiency, and speed translation from discovery to practical therapeutic testing.

The opportunity is positioned for institutions that already have a documented base of excellence and productivity in cystic fibrosis research. The FOA notes that NIDDK at the time supported five CF Research and Translation Centers at institutions with strong basic and clinical CF programs, underscoring that applicants are expected to demonstrate an existing critical mass of CF investigators, ongoing CF research activity, and a clear need for shared cores that will measurably enhance productivity and translation. Information about the broader NIDDK CF Center program was referenced through an NIDDK website link included in the announcement.

From a funding and administrative standpoint, this is a discretionary grant opportunity under the activity category listed as Food and Nutrition/Health, with CFDA number 93.847 (Diabetes, Digestive, and Kidney Diseases Extramural Research). The FOA projected an estimated total funding amount of $2,000,000 and anticipated making about 2 awards. The award ceiling was listed as $750,000, and there was no cost-sharing or matching requirement. Key dates in the source record show the opportunity was posted and created on April 1, 2011, with an original and current closing date of June 30, 2011, and an archive date of July 31, 2011.

Eligibility was broad and included many organization types across academia, government, nonprofit, and industry. Eligible applicants included public and state-controlled institutions of higher education, private institutions of higher education, nonprofits with or without 501(c)(3) status (other than institutions of higher education), for-profit organizations (including small businesses and other for-profits), and various levels of government (state, county, city/township), as well as special district governments and public housing authorities/Indian housing authorities. The announcement also explicitly called out additional eligible applicants such as Alaska Native and Native Hawaiian Serving Institutions, Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), tribal governments and tribal organizations (including those other than federally recognized in the eligibility listing), regional organizations, faith-based or community-based organizations, eligible federal agencies, and U.S. territories or possessions. The eligibility language suggests NIDDK intended to allow applications from a wide range of entities, while the practical competitiveness of a P30 core center typically depends on having an established CF research base and the ability to operate robust shared cores and center-wide programs.

For applicants seeking the full announcement text and requirements, the FOA provided an NIH Grants Guide link (http://grants.nih.gov/grants/guide/rfa-files/RFA-DK-11-004.html). The contact information in the source data points to the NIH Office of Extramural Research (OER) webmaster for technical access issues related to viewing or linking to the announcement.

Frequently Asked Questions (FAQs)

What is this funding opportunity?

This is the Cystic Fibrosis Research and Translation Core Centers (P30) funding opportunity, RFA-DK-11-004, a National Institutes of Health (NIH) grant program administered by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).

What is the main goal of the program?

The central purpose is to strengthen and accelerate cystic fibrosis (CF) research by supporting shared “core center” infrastructure that individual labs or standalone projects typically cannot support as efficiently on their own, and by promoting collaboration among investigators with a strong track record in CF research.

Does the P30 award fund a single research project?

No. The P30 mechanism is designed to fund a coordinated center framework that multiple investigators can use, rather than funding one individual research project.

What kinds of CF research does the center support?

The centers are built to serve both basic science and clinical/translational research needs in cystic fibrosis, with an emphasis on enabling the development and testing of new therapies.

What are the main components or activity areas supported by the center?

The FOA highlights three main activity areas: (1) Research Core services, (2) a Pilot and Feasibility (P&F) program, and (3) an Enrichment program.

What are Research Core services in this program?

Research Core services are shared core facilities or service units that provide specialized capabilities to cystic fibrosis investigators. These shared resources are intended to improve efficiency and expand what investigators can do by centralizing capabilities the institution wants multiple CF research teams to use.

What is the Pilot and Feasibility (P&F) program meant to do?

The Pilot and Feasibility program typically supports smaller, early-stage, or high-impact studies to generate preliminary data, encourage innovation, and help investigators launch new lines of CF research.

What is the Enrichment program?

The Enrichment program is generally aimed at building the scientific community and strengthening the research environment through activities such as seminars, visiting speakers, workshops, training opportunities, and other efforts that promote collaboration and scientific exchange.

Why does this program emphasize shared resources and a center framework?

The program is intended to expand institutional capacity, improve efficiency, and speed translation from discovery to practical therapeutic testing by providing shared services and center-wide programs that can be used by multiple investigators.

Are new applications allowed, or only renewals?

The opportunity solicits both new applications and renewal applications.

What kind of institution is this opportunity aimed at?

It is positioned for institutions that already have a documented base of excellence and productivity in cystic fibrosis research, including an existing critical mass of CF investigators and ongoing CF research activity.

How many CF Research and Translation Centers were supported at the time referenced in the FOA?

The FOA notes that NIDDK at the time supported five CF Research and Translation Centers at institutions with strong basic and clinical CF programs.

What does the FOA imply about competitiveness or readiness to apply?

While eligibility is broad, the FOA indicates applicants are expected to demonstrate an established CF research base and a clear need for shared cores that will measurably enhance productivity and translation.

Which agency administers this opportunity?

The program is administered through NIDDK, which is part of the NIH.

What is the activity category listed for this opportunity?

The activity category listed in the record is Food and Nutrition/Health.

What is the CFDA number for this opportunity?

The CFDA number listed is 93.847 (Diabetes, Digestive, and Kidney Diseases Extramural Research).

What is the estimated total funding amount and anticipated number of awards?

The FOA projected an estimated total funding amount of $2,000,000 and anticipated making about 2 awards.

What is the award ceiling?

The award ceiling listed was $750,000.

Is cost-sharing or matching required?

No. The opportunity stated there was no cost-sharing or matching requirement.

When was the opportunity posted and what were the key dates?

Key dates in the record show it was posted and created on April 1, 2011. The original and current closing date was June 30, 2011, and the archive date was July 31, 2011.

Who is eligible to apply?

Eligibility was broad and included many organization types across academia, government, nonprofit, and industry, including institutions of higher education, nonprofits (with or without 501(c)(3) status), for-profit organizations (including small businesses), and various levels of government.

Which higher-education institutions are explicitly listed as eligible?

Eligible higher-education institution types listed include public and state-controlled institutions of higher education and private institutions of higher education. The announcement also explicitly called out Alaska Native and Native Hawaiian Serving Institutions, Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), and Tribally Controlled Colleges and Universities (TCCUs).

Are nonprofits eligible even if they do not have 501(c)(3) status?

Yes. The eligibility list included nonprofits with or without 501(c)(3) status (other than institutions of higher education).

Are for-profit organizations eligible?

Yes. The eligibility list included for-profit organizations, including small businesses and other for-profits.

Which government entities are eligible?

The eligibility list included state governments, county governments, city or township governments, special district governments, public housing authorities/Indian housing authorities, eligible federal agencies, and U.S. territories or possessions.

Are tribal entities and tribal organizations eligible?

Yes. The announcement explicitly included tribal governments and tribal organizations, including those other than federally recognized (as stated in the eligibility listing), as well as Tribally Controlled Colleges and Universities (TCCUs).

Are faith-based or community-based organizations eligible?

Yes. The announcement explicitly called out faith-based or community-based organizations as additional eligible applicants.

Where can applicants find the full FOA text and requirements?

The FOA provided an NIH Grants Guide link: http://grants.nih.gov/grants/guide/rfa-files/RFA-DK-11-004.html

Who is listed as a contact for technical access issues with the announcement?

The contact information in the source data points to the NIH Office of Extramural Research (OER) webmaster for technical access issues related to viewing or linking to the announcement.

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