Opportunity Information: Apply for L10AS00179

  • The Bureau of Land Management in the natural resources sector is offering a public funding opportunity titled "Development of a 3 to 4 year controlled release PZP contraceptive vaccine for wild horses" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 15.229 Wild Horse and Burro Resource Management.
  • This funding opportunity was created on Jul 27, 2010 and posted on Jul 27, 2010.
  • Applicants must submit their applications by Aug 6, 2010. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $2,025,000.00 to eligible and selected applicants.
  • Each selected applicant is eligible to receive up to $405,000.00 in funding.
  • The number of recipients for this funding is limited to 1 candidate(s).
  • Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
Apply for L10AS00179

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Opportunity Summary:

This grant opportunity, issued by the U.S. Department of the Interior's Bureau of Land Management (BLM), sought a project to develop a longer-lasting immunocontraceptive vaccine for wild horse mares using PZP (porcine zona pellucida). The central goal was to produce a formulation that could provide reliable contraception for approximately 3 to 4 years from a single treatment, using controlled-release technology. In practical terms, the BLM was looking for a temporary, reversible fertility-control tool that would reduce wild horse population growth rates while avoiding repeated roundups or frequent re-darting, and that could be applied in a minimally invasive way, ideally through one injection.

The opportunity was structured as a discretionary cooperative agreement, meaning the selected recipient would likely work in close coordination with the BLM rather than operating entirely independently. The activity area was classified under Natural Resources, and it aligned with the federal wild horse and burro management program (CFDA 15.229, Wild Horse and Burro Resource Management). The announcement emphasized the need for a contraceptive approach that is effective yet not permanent, supporting management objectives by lowering foaling rates over multiple breeding seasons without sterilization. The mention of "controlled release" indicates a technical focus on delivery systems that release vaccine components over time to maintain an immune response long enough to cover multiple years, reducing the need for booster doses.

Funding for the opportunity was estimated at $2,025,000 in total, with an expectation of one award. The stated award range ran from a floor of $100,000 to a ceiling of $405,000, suggesting the work may have been planned as a multi-year effort with phased funding or incremental cooperative agreement actions rather than a single lump-sum grant. There was no cost-sharing or matching requirement, which typically lowers barriers for applicants and signals the agency expected to fully fund the federal share of the proposed research and development effort.

Eligibility was listed as unrestricted, open to any type of applicant entity, subject to any additional eligibility clarifications in the full announcement. The posting date and creation date were both July 27, 2010, with an original and current closing date of August 6, 2010, and an archive date of August 27, 2010. The short application window suggests the BLM may have been targeting organizations already positioned to perform specialized vaccine development and delivery-system research, or that it was part of a time-sensitive program need.

For applicants needing help obtaining the full announcement, the contact listed was Susan Kaller, Grants Management Officer, with a phone number (775-861-6559) and email (susankaller@blm.gov). The listing also pointed to Grants.gov for the additional information link and full application materials, indicating that applications were expected to be submitted and managed through standard federal grants systems.

Frequently Asked Questions (FAQ)

What is this grant opportunity about?

This opportunity from the U.S. Department of the Interior, Bureau of Land Management (BLM) sought a project to develop a longer-lasting immunocontraceptive vaccine for wild horse mares using PZP (porcine zona pellucida). The goal was to create a formulation that could provide reliable contraception for about 3 to 4 years from a single treatment.

What problem was the BLM trying to solve with this project?

The BLM was looking for a temporary, reversible fertility-control tool to reduce wild horse population growth rates while avoiding repeated roundups or frequent re-darting. The intent was to lower foaling rates over multiple breeding seasons without using permanent sterilization.

What does "controlled-release technology" mean in this context?

In this announcement, "controlled release" refers to delivery systems designed to release vaccine components over time. The purpose is to maintain an immune response long enough to provide contraception over multiple years, reducing or eliminating the need for booster doses.

How long was the contraceptive effect expected to last?

The central performance target described in the opportunity was reliable contraception for approximately 3 to 4 years from a single treatment.

Was the contraception intended to be permanent?

No. The announcement emphasized an approach that is effective but not permanent, supporting management objectives by reducing foaling rates without sterilization.

How was the vaccine ideally supposed to be administered?

The BLM indicated a preference for a minimally invasive method, ideally through one injection, to reduce the need for repeated handling or re-darting.

What type of funding mechanism was used?

The opportunity was structured as a discretionary cooperative agreement. This generally indicates that the selected recipient would work in close coordination with the BLM, rather than operating entirely independently.

What program area did this opportunity fall under?

The activity area was classified under Natural Resources, and it aligned with the federal wild horse and burro management program (CFDA 15.229, Wild Horse and Burro Resource Management).

How much funding was available in total?

Total funding was estimated at $2,025,000, with an expectation of one award.

What was the stated award range?

The stated award range ran from a minimum (floor) of $100,000 to a maximum (ceiling) of $405,000.

Why does the award range look smaller than the total estimated funding?

Based on the information provided, the award structure suggests the work may have been planned as a multi-year effort with phased funding or incremental cooperative agreement actions rather than a single lump-sum award.

How many awards was the BLM expecting to make?

The opportunity indicated an expectation of one award.

Was cost sharing or matching required?

No. The announcement stated there was no cost-sharing or matching requirement.

Who was eligible to apply?

Eligibility was listed as unrestricted, meaning it was open to any type of applicant entity, subject to any additional eligibility clarifications in the full announcement.

When was the opportunity posted?

The posting date and creation date were both July 27, 2010.

What was the application deadline?

The original and current closing date was August 6, 2010.

When was the opportunity archived?

The archive date listed for the opportunity was August 27, 2010.

How long was the application window?

Based on the posting date (July 27, 2010) and closing date (August 6, 2010), the application period was short. The announcement text suggests this may have favored organizations already positioned to perform specialized vaccine development and delivery-system research, or it may have reflected a time-sensitive program need.

Where could applicants find the full announcement and application materials?

The listing pointed to Grants.gov for the additional information link and full application materials, indicating applications were expected to be submitted and managed through standard federal grants systems.

Who was the contact person for questions or help obtaining the full announcement?

The contact listed was Susan Kaller, Grants Management Officer. Phone: 775-861-6559. Email: susankaller@blm.gov.

What species and population was the vaccine intended for?

The project focus was specifically on wild horse mares as part of the federal wild horse and burro management program.

What specific contraceptive approach did the announcement mention?

The opportunity specifically referenced PZP (porcine zona pellucida) as the immunocontraceptive basis for the vaccine formulation.

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