Opportunity Information: Apply for PA 06 400
Apply for PA 06 400
- The National Institutes of Health in the education health sector is offering a public funding opportunity titled "Developmental Projects in Complementary Approaches to Cancer Care (R21)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.213 Research and Training in Complementary and Integrative Health 93.361 Nursing Research 93.395 Cancer Treatment Research.
- This funding opportunity was created on Dec 5, 2008 and posted on May 9, 2006.
- Applicants must submit their applications by May 7, 2009 Multiple Receipt Dates See Link to Full Announcement for details.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $200,000.00 in funding.
- Eligible applicants include: Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education State governments Native American tribal organizations (other than Federally recognized tribal governments) Special district governments Public housing authorities/Indian housing authorities Native American tribal governments (Federally recognized) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Public and State controlled institutions of higher education Private institutions of higher education County governments For profit organizations other than small businesses Others (see text field entitled Additional Information on Eligibility for clarification) City or township governments Independent school districts.
- Foreign institutions are eligible to apply. Eligible agencies of the Federal Government can apply. Faith based or community based organizations can apply.
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Opportunity Summary:
The National Institutes of Health (NIH) funding opportunity titled "Developmental Projects in Complementary Approaches to Cancer Care (R21)" (Funding Opportunity Number PA 06 400) supports early stage, exploratory research focused on complementary approaches in cancer care. The main goal is to help researchers generate the kind of groundwork that can justify and enable larger, longer term projects later on. In practical terms, this program is designed to fund studies that test whether proposed methods are feasible, strengthen the scientific rationale behind a complementary intervention or approach, and produce preliminary data that would make a future, more definitive application competitive. A second major purpose is to bring new and promising investigators into complementary cancer research by using the R21 exploratory/developmental grant structure, which is commonly used at NIH to encourage innovative ideas that are not yet ready for full scale trials or extensive mechanistic programs.
This opportunity uses the NIH R21 mechanism, meaning it is intended for developmental projects rather than mature programs of research. Projects can be basic or clinical, as long as they address complementary approaches relevant to cancer care and align with the announcement's emphasis on building a foundation for subsequent work. Because the program expects applications to vary widely in their scientific scope and methods, award sizes and project structures can vary as well. However, the funding and time limits are clearly defined: the total project period cannot exceed 2 years, and direct costs are capped at 275,000 dollars over the two year period, with no more than 200,000 dollars in direct costs allowed in any single year. There is no cost sharing or matching requirement listed for this program, which is typical for NIH research grants.
The number of awards is not predetermined. NIH makes awards under this announcement based on two constraints: whether funds are available in the relevant budget cycle and whether enough high quality, meritorious applications are received. As a result, applicants should treat the program as competitive and dependent on peer review outcomes and institute funding decisions rather than expecting a fixed number of funded projects in any given round.
Eligibility is broad and includes a wide range of organizations that can serve as applicants. Eligible entities include for profit and non profit organizations, public and private institutions such as universities, colleges, hospitals, and laboratories, as well as units of state and local government. The announcement explicitly allows applications from domestic and foreign institutions, eligible federal government agencies, and faith based or community based organizations. It also includes Indian/Native American Tribal Governments (both federally recognized and other than federally recognized) and Indian/Native American tribally designated organizations. The source listing also reflects eligibility across multiple government types (for example, county governments, city or township governments, special district governments, and independent school districts), indicating NIH's intent to keep the applicant pool open as long as the organization can appropriately conduct and manage the proposed research.
On the investigator side, the opportunity is similarly inclusive. Any individual with the skills, knowledge, and resources to carry out the proposed work may serve as the Project Director/Principal Investigator (PD/PI), provided they are affiliated with an eligible applicant organization. NIH also reiterates its standing encouragement for applications from individuals from underrepresented racial and ethnic groups and individuals with disabilities. Applicants are allowed to submit more than one application under this announcement as long as each submission is scientifically distinct, which is useful for teams that have multiple independent pilot concepts or separate complementary approach strategies they want to test.
Administratively, the program is categorized as a discretionary grant and falls under health and education related funding activity areas. The CFDA numbers associated with the announcement include 93.213 (Research and Training in Complementary and Integrative Health), 93.361 (Nursing Research), and 93.395 (Cancer Treatment Research), which signals that the topic sits at the intersection of cancer treatment research and complementary/integrative health, with potential relevance to supportive care, symptom management, and related clinical outcomes depending on the proposed study. The original posting date is May 9, 2006, with multiple receipt dates referenced in the full announcement, and the archived record indicates closing milestones that culminated in 2009. For complete application instructions, receipt dates, and the most precise requirements, NIH directs applicants to the full announcement page at http://grants.nih.gov/grants/guide/pa-files/PA-06-400.html (noting that the URL may require formatting adjustments if copied exactly from a database listing).
Frequently Asked Questions (FAQs)
1) What is the official title and funding opportunity number for this NIH grant?
The opportunity is titled "Developmental Projects in Complementary Approaches to Cancer Care (R21)". The Funding Opportunity Number is PA-06-400.
2) What is the main purpose of this funding opportunity?
This program supports early-stage, exploratory research on complementary approaches in cancer care. The goal is to help researchers build the groundwork needed for future, larger, longer-term projects by demonstrating feasibility, strengthening scientific rationale, and generating preliminary data.
3) What kinds of studies is this program designed to fund?
The announcement emphasizes developmental work, including studies that:
- Test whether proposed methods are feasible
- Strengthen the scientific rationale for a complementary intervention or approach
- Generate preliminary data that can support a later, more definitive NIH application
4) What grant mechanism does this opportunity use?
This opportunity uses the NIH R21 exploratory/developmental grant mechanism. It is intended for developmental projects, not mature programs of research.
5) Is the research expected to be basic science, clinical, or both?
Projects can be basic or clinical, as long as they address complementary approaches relevant to cancer care and align with the emphasis on building a foundation for later work.
6) What is meant by "complementary approaches" in the context of this announcement?
Based on the information provided, the announcement focuses on complementary approaches relevant to cancer care and sits at the intersection of cancer treatment research and complementary/integrative health. (Specific modalities or examples are not listed in the summary provided.)
7) What are the maximum project duration and budget limits?
The limits described are:
- Project period: up to 2 years total
- Direct costs: up to $275,000 total over the 2-year project period
- Annual direct cost cap: no more than $200,000 in any single year
8) Are applicants required to provide cost sharing or matching funds?
No. The summary states there is no cost sharing or matching requirement listed for this program.
9) How many awards will NIH make under this announcement?
The number of awards is not predetermined. Awards depend on:
- Availability of funds in the relevant budget cycle
- Whether NIH receives enough high-quality, meritorious applications
10) Does this opportunity guarantee funding if an application is submitted?
No. The program is competitive and depends on peer review outcomes and NIH institute funding decisions, and there is no fixed number of awards in a given round.
11) What types of organizations are eligible to apply?
Eligibility is broad. The summary lists eligible applicants including:
- For-profit and non-profit organizations
- Public and private institutions (universities, colleges, hospitals, laboratories)
- Units of state and local government
- Domestic and foreign institutions
- Eligible federal government agencies
- Faith-based or community-based organizations
- Indian/Native American Tribal Governments (federally recognized and other than federally recognized)
- Indian/Native American tribally designated organizations
- Various local government types (for example, county governments, city/township governments, special district governments, and independent school districts)
12) Can foreign institutions apply?
Yes. The announcement explicitly allows applications from domestic and foreign institutions.
13) Who is eligible to serve as the Project Director/Principal Investigator (PD/PI)?
Any individual with the skills, knowledge, and resources to carry out the proposed work may serve as PD/PI, as long as they are affiliated with an eligible applicant organization.
14) Does NIH encourage applications from specific investigator groups?
Yes. NIH reiterates its encouragement for applications from:
- Individuals from underrepresented racial and ethnic groups
- Individuals with disabilities
15) Can the same applicant submit more than one application?
Yes. Applicants may submit more than one application under this announcement as long as each application is scientifically distinct.
16) What general research stage is this opportunity meant for?
It is meant for early-stage or exploratory research that is not yet ready for a full-scale trial or extensive mechanistic program, but that can produce the groundwork for later, more definitive studies.
17) What funding activity areas are associated with this program?
The program is categorized as a discretionary grant and falls under health and education related funding activity areas.
18) What CFDA numbers are associated with this opportunity, and what do they suggest?
The CFDA numbers listed are:
- 93.213 (Research and Training in Complementary and Integrative Health)
- 93.361 (Nursing Research)
- 93.395 (Cancer Treatment Research)
These suggest the topic sits at the intersection of complementary/integrative health and cancer treatment research, with potential relevance to areas like supportive care and symptom management depending on the proposed study (as described in the summary).
19) When was this opportunity originally posted, and is it still current?
The original posting date is May 9, 2006. The archived record indicates closing milestones culminating in 2009. The summary also notes that multiple receipt dates were referenced in the full announcement.
20) Where can applicants find the full announcement and official application instructions?
NIH directs applicants to the full announcement page at:
http://grants.nih.gov/grants/guide/pa-files/PA-06-400.html
The summary notes the URL may require formatting adjustments if copied from a database listing.
21) Are award sizes and project structures the same for every funded project?
No. The summary notes that applications may vary widely in scientific scope and methods, so award sizes and project structures can vary as well, within the defined R21 time and direct cost limits.
22) What is a practical way to think about what NIH wants from an R21 under this announcement?
In practical terms, the announcement is looking for projects that can credibly show an approach is workable (feasibility), strengthen the scientific basis for why the approach should work (rationale), and produce enough early evidence (preliminary data) to make a later, larger application more competitive.
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Previous opportunity: The Influence of Religiosity and Spirituality on Health Risk Behaviors in Children and Adolescents (R21)
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Applicants also applied for:
Applicants who have applied for this opportunity (PA 06 400) also looked into and applied for these:
| Funding Opportunity |
|---|
| Studies of Energy Balance and Cancer in Humans (R21) Apply for PA 06 405 Funding Number: PA 06 405 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| Phased Innovation Research in Cancer Prognosis and Prediction (R21/R33) Apply for PA 06 434 Funding Number: PA 06 434 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| Phase II Developmental Research in Cancer Prognosis and Prediction (R33) Apply for PA 06 435 Funding Number: PA 06 435 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| The Development of Frontal Cortex and Limbic System and their roles in Drug Abuse or Mental Health (R21) Apply for PA 06 445 Funding Number: PA 06 445 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| Drug Abuse Dissertation Research Epidemiology, Prevention, Treatment, Services, and Women and Sex/Gender Differences (R36) Apply for PAR 06 476 Funding Number: PAR 06 476 Agency: National Institutes of Health Category: Education Health Funding Amount: $50,000 |
| Behavioral and Integrative Treatment Development Program (R21) Apply for PA 06 487 Funding Number: PA 06 487 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| Behavioral and Integrative Treatment Development Program (R03) Apply for PA 06 488 Funding Number: PA 06 488 Agency: National Institutes of Health Category: Education Health Funding Amount: $50,000 |
| Health Services Research on Practice Improvement Utilizing Community Treatment Programs within the National Drug Abuse Clinical Trials Network (CTN) (R21) Apply for PA 06 496 Funding Number: PA 06 496 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| Health Services Research on Practice Improvement Utilizing Community Treatment Programs within the National Drug Abuse Clinical Trials Network (CTN) (R03) Apply for PA 06 497 Funding Number: PA 06 497 Agency: National Institutes of Health Category: Education Health Funding Amount: $50,000 |
| Exfoliated Cells and Circulating DNA in Cancer Detection and Diagnosis(R21) Apply for PA 06 499 Funding Number: PA 06 499 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| Pathophysiology of Bisphosphonates associated Osteonecrosis of the Jaw (R03) Apply for PA 06 502 Funding Number: PA 06 502 Agency: National Institutes of Health Category: Education Health Funding Amount: $50,000 |
| Pathophysiology of Bisphosphonates associated Osteonecrosis of the Jaw (R21) Apply for PA 06 501 Funding Number: PA 06 501 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| National Cancer Institute (NCI) Cancer Education and Career Development Program (R25) Apply for PAR 06 511 Funding Number: PAR 06 511 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Development and Application of PET and SPECT Imaging Ligands as Biomarkers for Drug Discovery and for Pathophysiological Studies of CNS Disorders (R21) Apply for PA 06 461 Funding Number: PA 06 461 Agency: National Institutes of Health Category: Education Health Funding Amount: $250,000 |
| Development and Application of PET and SPECT Imaging Ligands as Biomarkers for Drug Discovery and for Pathophysiological Studies of CNS Disorders (R33) Apply for PA 06 462 Funding Number: PA 06 462 Agency: National Institutes of Health Category: Education Health Funding Amount: $500,000 |
| Development and Application of PET and SPECT Imaging Ligands as Biomarkers for Drug Discovery and for Pathophysiological Studies of CNS Disorders (Phased Innovation Award R21/R33) Apply for PA 06 463 Funding Number: PA 06 463 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Dissemination and Implementation Research in Health (R03) Apply for PAR 06 520 Funding Number: PAR 06 520 Agency: National Institutes of Health Category: Education Health Funding Amount: $250,000 |
| Dissemination and Implementation Research in Health (R21) Apply for PAR 06 521 Funding Number: PAR 06 521 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| Translational Research for the Prevention and Control of Diabetes and Obesity (R18) Apply for PAR 06 532 Funding Number: PAR 06 532 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Behavioral Science Track Award for Rapid Transition (B/START) (R03) Apply for PAR 06 541 Funding Number: PAR 06 541 Agency: National Institutes of Health Category: Education Health Funding Amount: $50,000 |
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