Opportunity Information: Apply for RFA DK 14 014
Apply for RFA DK 14 014
- The National Institutes of Health in the food and nutrition health sector is offering a public funding opportunity titled "Diabetes Impact Award Closed Loop Technologies Clinical, Physiological and Behavioral Approaches to Improve Type 1 Diabetes Outcomes (DP3)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research.
- This funding opportunity was created on May 14, 2014 and posted on May 14, 2014.
- Applicants must submit their applications by Nov 24, 2014. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $10,000,000.00 to eligible and selected applicants.
- Eligible applicants include: Public and State controlled institutions of higher education Native American tribal governments (Federally recognized) County governments Public housing authorities/Indian housing authorities Small businesses Private institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses Native American tribal organizations (other than Federally recognized tribal governments) Others (see text field entitled Additional Information on Eligibility for clarification) State governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education City or township governments Independent school districts Special district governments.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:
The grant opportunity RFA-DK-14-014, titled "Diabetes Impact Award: Closed Loop Technologies - Clinical, Physiological and Behavioral Approaches to Improve Type 1 Diabetes Outcomes (DP3)," is a National Institutes of Health (NIH) discretionary grant program focused on advancing practical closed-loop "artificial pancreas" style systems for people with type 1 diabetes. The core goal is to support human research that develops and/or rigorously tests integrated systems that connect continuous glucose monitoring (CGM) with automated delivery of pancreatic hormones in a closed-loop setup. The emphasis is on building a system that is not only scientifically sound, but also highly reliable, wearable, portable, and easy for patients to operate in real life, with the broader intent of improving both glucose control and day-to-day quality of life.
A defining feature of this FOA is that it is limited to human studies; proposals that are purely preclinical, bench-based, or animal-only are not considered responsive. The program is aimed at bridging clinical performance with real-world usability, meaning applicants are expected to think beyond algorithm accuracy and address practical issues that often determine whether a device actually helps patients outside controlled settings. That includes considerations such as safety, reliability, the user experience, and behavioral factors that affect adherence and effective use, all while maintaining tight and safe glycemic control. Because the title explicitly references clinical, physiological, and behavioral approaches, the FOA signals interest in multidisciplinary projects that combine device engineering and clinical investigation with human factors, patient behavior, training, and other elements that influence outcomes in everyday living.
The opportunity is administered under the NIH, with the activity area tied to Diabetes, Digestive, and Kidney Diseases extramural research (CFDA 93.847), and it falls under the Food and Nutrition/Health activity category. The total estimated funding amount listed for the program is $10,000,000. There is no cost sharing or matching requirement, which generally lowers barriers for applicants by not requiring institutional funds to be committed as a condition of eligibility.
Eligibility is broad and includes a wide range of domestic and international entities. Eligible applicants include public and state-controlled institutions of higher education, private institutions of higher education, nonprofits (including those with and without 501(c)(3) status, with some distinctions), small businesses, and other for-profit organizations that are not small businesses. Government entities at multiple levels are also eligible, including state governments, county governments, city or township governments, independent school districts, special district governments, and public housing authorities/Indian housing authorities. The FOA also allows applications from Native American tribal governments (federally recognized) and Native American tribal organizations (including those other than federally recognized tribal governments), as well as tribally controlled colleges and universities.
The eligibility language further clarifies that several institution types and organizational categories are explicitly included, such as Historically Black Colleges and Universities (HBCUs), Hispanic-Serving Institutions, Alaska Native and Native Hawaiian Serving Institutions, and Asian American and Native American Pacific Islander-Serving Institutions (AANAPISIs). Faith-based and community-based organizations are listed as eligible, along with regional organizations and eligible agencies of the federal government. Importantly, non-U.S. entities are eligible to apply, including foreign organizations and foreign institutions, and foreign components (as defined in NIH policy) are allowed. Non-domestic components of U.S. organizations are also eligible. This broad eligibility suggests NIH interest in accelerating progress wherever strong teams exist, while still keeping the work anchored in human studies.
In terms of timing and status, this FOA was posted and created on May 14, 2014. The original and current closing date was November 24, 2014, with an archive date of December 25, 2014, indicating the opportunity is no longer active as a current application cycle but remains available for reference as an archived announcement. The official NIH information page for the announcement was provided through the NIH grants guide at: http://grants.nih.gov/grants/guide/rfa-files/RFA-DK-14-014.html.
For practical administrative support, NIH provided contact pathways through the NIH Office of Extramural Research (OER) webmaster for access issues or problems linking to the announcement, using the email address FBOWebmaster@OD.NIH.GOV.
FAQs - RFA-DK-14-014 (Diabetes Impact Award: Closed Loop Technologies - DP3)
What is the full title and number of this grant opportunity?
The opportunity is RFA-DK-14-014, titled "Diabetes Impact Award: Closed Loop Technologies - Clinical, Physiological and Behavioral Approaches to Improve Type 1 Diabetes Outcomes (DP3)."
Which federal agency runs this funding opportunity?
This funding opportunity is administered under the National Institutes of Health (NIH).
What is the main purpose of this FOA?
The core purpose is to advance practical closed-loop "artificial pancreas" style systems for people with type 1 diabetes by supporting human research that develops and/or rigorously tests integrated systems connecting continuous glucose monitoring (CGM) with automated delivery of pancreatic hormones in a closed-loop setup.
What types of systems or technologies does the FOA emphasize?
The FOA emphasizes integrated closed-loop systems that link CGM with automated hormone delivery. It highlights not only scientific and clinical performance, but also reliability, wearability, portability, and ease of use in real-life settings.
Is this funding opportunity limited to human studies?
Yes. A defining feature is that it is limited to human studies. Proposals that are purely preclinical, bench-based, or animal-only are described as not responsive.
Are preclinical, bench, or animal-only studies allowed under this FOA?
No. The FOA indicates that purely preclinical, bench-based, or animal-only proposals are not considered responsive because the program is explicitly focused on human research.
Beyond clinical performance, what does NIH want applicants to address?
The FOA is aimed at bridging clinical performance with real-world usability. Applicants are expected to address practical issues that influence whether a device helps patients outside controlled settings, including safety, reliability, user experience, and behavioral factors that affect adherence and effective use.
How does the FOA connect clinical, physiological, and behavioral approaches?
By explicitly referencing clinical, physiological, and behavioral approaches, the FOA signals interest in multidisciplinary projects that combine device engineering and clinical investigation with human factors, patient behavior, training, and other real-world elements that influence outcomes.
What outcomes is this FOA trying to improve for people with type 1 diabetes?
The stated intent is to improve both glucose control and day-to-day quality of life by supporting closed-loop systems that maintain tight and safe glycemic control while being practical for everyday use.
What is the activity category or topic area associated with this opportunity?
The opportunity is listed under the Food and Nutrition/Health activity category, with the activity area tied to Diabetes, Digestive, and Kidney Diseases extramural research.
What CFDA number is associated with this opportunity?
The CFDA number provided is 93.847.
How much total funding is estimated for this program?
The total estimated funding amount listed is $10,000,000.
Is cost sharing or matching required?
No. The opportunity states there is no cost sharing or matching requirement.
Who is eligible to apply?
Eligibility is broad and includes domestic and international entities. Eligible applicants include public and state-controlled institutions of higher education, private institutions of higher education, nonprofits (with and without 501(c)(3) status, with some distinctions), small businesses, and other for-profit organizations that are not small businesses.
Are government organizations eligible to apply?
Yes. Eligible government entities include state governments, county governments, city or township governments, independent school districts, special district governments, and public housing authorities/Indian housing authorities.
Are tribal governments and tribal organizations eligible?
Yes. The FOA allows applications from Native American tribal governments (federally recognized) and Native American tribal organizations (including those other than federally recognized tribal governments). Tribally controlled colleges and universities are also included as eligible.
Are minority-serving institutions explicitly included in eligibility?
Yes. The eligibility language explicitly includes Historically Black Colleges and Universities (HBCUs), Hispanic-Serving Institutions, Alaska Native and Native Hawaiian Serving Institutions, and Asian American and Native American Pacific Islander-Serving Institutions (AANAPISIs).
Are faith-based or community-based organizations eligible to apply?
Yes. Faith-based and community-based organizations are listed among eligible applicants.
Are non-U.S. organizations allowed to apply?
Yes. Non-U.S. entities are eligible, including foreign organizations and foreign institutions.
Are foreign components allowed under NIH policy for this FOA?
Yes. The FOA notes that foreign components (as defined in NIH policy) are allowed.
Can a U.S. organization include non-domestic components?
Yes. Non-domestic components of U.S. organizations are described as eligible.
When was this FOA posted and created?
The FOA was posted and created on May 14, 2014.
What was the closing date for applications?
The original and current closing date listed was November 24, 2014.
Is this funding opportunity still open?
No. The archive date is December 25, 2014, indicating the opportunity is no longer active and is available for reference as an archived announcement.
Where can applicants find the official NIH announcement page?
The NIH Grants Guide page provided is: http://grants.nih.gov/grants/guide/rfa-files/RFA-DK-14-014.html
Who should be contacted for technical access issues or linking problems with the announcement?
NIH provided the NIH Office of Extramural Research (OER) webmaster contact for access issues or problems linking to the announcement: FBOWebmaster@OD.NIH.GOV.
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| Diabetes Impact Award Closed Loop Technologies Development and Integration of Novel Components for an Automated Artificial Pancreas System (DP3) Apply for RFA DK 14 015 Funding Number: RFA DK 14 015 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: Case Dependent |
| Nutrition Obesity Research Centers (NORCs) (P30) Apply for RFA DK 14 002 Funding Number: RFA DK 14 002 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $750,000 |
| Silvio O. Conte Digestive Diseases Research Core Centers (P30) Apply for RFA DK 14 012 Funding Number: RFA DK 14 012 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $750,000 |
| Increasing the Quality and Efficiency of Clinical Trials (R18) Apply for RFA FD 14 017 Funding Number: RFA FD 14 017 Agency: Food Drug Administration Category: Food and Nutrition Health Funding Amount: $7,500,000 |
| U.S. India Bilateral Collaborative Research Partnerships (CRP) on Diabetes Research (R21) Apply for RFA DK 14 006 Funding Number: RFA DK 14 006 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $275,000 |
| Polycystic Kidney Disease (PKD) Research and Translation Core Centers (P30) Apply for RFA DK 14 013 Funding Number: RFA DK 14 013 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $750,000 |
| Research Using Biosamples From Selected Type 1 Diabetes Clinical Studies (DP3) Apply for PAR 14 257 Funding Number: PAR 14 257 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $4,000,000 |
| Research Using Subjects From Selected Type 1 Diabetes Clinical Studies (Living Biobank) (DP3) Apply for PAR 14 258 Funding Number: PAR 14 258 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $7,000,000 |
| Chronic Kidney Disease Biomarkers Consortium (CKD BioCon) (U01) Apply for RFA DK 14 011 Funding Number: RFA DK 14 011 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $450,000 |
| Improving Diabetes Management in Young Children with Type 1 Diabetes (DP3) Apply for RFA DK 14 022 Funding Number: RFA DK 14 022 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: Case Dependent |
| Critical Path Public Private Partnerships Apply for RFA FD 14 089 Funding Number: RFA FD 14 089 Agency: Food Drug Administration Category: Food and Nutrition Health Funding Amount: $10,500,000 |
| NIDDK Mentored Research Scientist Development Award (K01) Apply for PAR 14 266 Funding Number: PAR 14 266 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: Case Dependent |
| Limited Competition Data Coordinating Center for The Environmental Determinants of Diabetes in the Young (TEDDY) Study (UC4) Apply for RFA DK 14 505 Funding Number: RFA DK 14 505 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $20,000,000 |
| NIAID SBIR Technology Transfer Direct Phase II (SBIR TT) (R44) Apply for RFA AI 14 049 Funding Number: RFA AI 14 049 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $1,000,000 |
| NIDDK Cooperative Hematology Specialized Core Centers (U54) Apply for RFA DK 14 001 Funding Number: RFA DK 14 001 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $1,000,000 |
| Limited Competition for the Continuation of the Adult Acute Liver Failure Study Group (U01) Apply for RFA DK 14 504 Funding Number: RFA DK 14 504 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $3,500,000 |
| NIDDK Physician Scientist Diversity Mentoring Award (K05) Apply for RFA DK 14 005 Funding Number: RFA DK 14 005 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: Case Dependent |
| NIDDK Central Repositories Non renewable Sample Access (X01) Apply for PAR 14 301 Funding Number: PAR 14 301 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: Case Dependent |
| Type 1 Diabetes TrialNet Clinical Centers (U01) Apply for RFA DK 14 016 Funding Number: RFA DK 14 016 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $450,000 |
| Prevention of Lower Urinary Tract Symptoms in Women Bladder Health Scientific and Data Coordinating Center (PLUS SDCC) (U01) Apply for RFA DK 14 018 Funding Number: RFA DK 14 018 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $750,000 |
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