Opportunity Information: Apply for RFA DK 14 015
Apply for RFA DK 14 015
- The National Institutes of Health in the food and nutrition health sector is offering a public funding opportunity titled "Diabetes Impact Award Closed Loop Technologies Development and Integration of Novel Components for an Automated Artificial Pancreas System (DP3)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research.
- This funding opportunity was created on May 14, 2014 and posted on May 14, 2014.
- Applicants must submit their applications by Nov 24, 2014. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $6,000,000.00 to eligible and selected applicants.
- Eligible applicants include: State governments Public and State controlled institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) Independent school districts Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal governments (Federally recognized) Public housing authorities/Indian housing authorities City or township governments For profit organizations other than small businesses Private institutions of higher education Special district governments County governments.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:
The NIH funding opportunity RFA-DK-14-015, titled "Diabetes Impact Award: Closed Loop Technologies Development and Integration of Novel Components for an Automated Artificial Pancreas System (DP3)," was a discretionary grant program aimed at accelerating next-generation technology for automated glucose control in people with Type 1 diabetes. The core purpose was to support original research that creates or significantly advances new components that could be integrated into a wearable, portable, automated "closed-loop" system, meaning a system that can sense glucose levels and automatically adjust insulin (and potentially other hormones or interventions) to maintain near-physiological glucose control with minimal user input. In practical terms, the FOA was focused on enabling the development of an improved artificial pancreas ecosystem by funding innovation in the enabling technologies that make closed-loop control safer, more accurate, more reliable, and more usable in everyday life.
This announcement emphasized "development and integration of novel components," which signals two key expectations. First, applicants were expected to propose technology development, not just basic science or observational clinical work. Second, the work needed a clear path toward integration into a functioning closed-loop platform, rather than being an isolated device concept with no plan for interoperability. The target end state described in the FOA was a wearable and portable system capable of automated operation, reflecting an interest in real-world feasibility: small form factors, robust performance outside of tightly controlled clinical settings, and the ability to support physiological glucose regulation as closely as possible for individuals living with Type 1 diabetes.
Administratively, the opportunity was issued by the National Institutes of Health (NIH) under the activity area associated with the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), reflected by the CFDA number 93.847 (Diabetes, Digestive, and Kidney Diseases Extramural Research). The funding instrument was a grant, and the opportunity category was discretionary. The program did not require cost sharing or matching, which typically lowers barriers for applicants by allowing projects to be built primarily around NIH support rather than requiring non-federal financial contributions.
In terms of timing and lifecycle, the FOA was posted and created on May 14, 2014, with an original and current closing date of November 24, 2014. The opportunity was later archived on December 25, 2014, indicating it is no longer open for applications. The estimated total funding level for the announcement was $6,000,000, which suggests NIH intended to make a meaningful investment across a small number of high-impact awards or a moderate number of awards depending on project scope and budget structures.
Eligibility was intentionally broad, spanning much of the research and innovation landscape. Eligible applicants included state and local governments (such as city/township governments, county governments, and special district governments), public housing authorities/Indian housing authorities, public and state-controlled institutions of higher education, private institutions of higher education, independent school districts, and a wide range of nonprofit and for-profit organizations (including small businesses, and for-profit entities other than small businesses). The FOA also explicitly included tribal governments (federally recognized and other than federally recognized) and tribal organizations, along with tribally controlled colleges and universities (TCCUs). It extended eligibility to organizations serving specific communities, such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Alaska Native and Native Hawaiian-serving institutions, and Asian American Native American Pacific Islander-serving institutions (AANAPISIs). Faith-based and community-based organizations were eligible as well. Notably, the opportunity allowed participation by non-U.S. entities: foreign organizations and foreign institutions could apply, non-U.S. components of U.S. organizations were eligible, and foreign components (as defined in the NIH Grants Policy Statement) were allowed. That international openness is consistent with NIH’s interest in bringing the best engineering, biomedical device development, and translational science talent to bear on a complex, global health challenge.
For applicants or stakeholders looking for official details at the time, NIH provided an additional information link to the full FOA text hosted on the NIH grants website. NIH also listed contact support through the NIH Office of Extramural Research (OER) webmaster email addresses for access issues or linking problems, reflecting standard NIH practice for technical assistance rather than scientific program guidance in the summary text provided here.
Overall, the opportunity can be understood as a targeted push to move closed-loop artificial pancreas technology forward by funding innovative, integratable components and systems-level development, with an emphasis on wearability, portability, and automation suitable for people living with Type 1 diabetes in real-world conditions.
FAQs: NIH RFA-DK-14-015 (Diabetes Impact Award - Closed Loop Technologies / Artificial Pancreas, DP3)
What is RFA-DK-14-015?
RFA-DK-14-015 is an NIH funding opportunity titled "Diabetes Impact Award: Closed Loop Technologies Development and Integration of Novel Components for an Automated Artificial Pancreas System (DP3)." It was a discretionary grant program focused on accelerating next-generation technology for automated glucose control in people with Type 1 diabetes.
Who issued this funding opportunity?
The opportunity was issued by the National Institutes of Health (NIH) and is associated with the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), as reflected by CFDA number 93.847.
What was the main goal of this program?
The core goal was to support original research that creates or significantly advances new components that can be integrated into a wearable, portable, automated closed-loop system (an "artificial pancreas" system) that can sense glucose levels and automatically adjust insulin (and potentially other hormones or interventions) to maintain near-physiological glucose control with minimal user input.
What does "closed-loop" mean in the context of this FOA?
In this context, "closed-loop" refers to an automated system that senses glucose levels and then automatically adjusts insulin delivery (and possibly other interventions) to regulate blood glucose, aiming to reduce the need for continuous manual user decisions.
What types of projects were emphasized: basic science or technology development?
This announcement emphasized technology development and integration. It signaled that applicants were expected to propose development work (not just basic science or observational clinical work) and to show a clear path toward integrating proposed components into a functioning closed-loop platform.
What does "development and integration of novel components" imply for applicants?
It implies two key expectations: (1) the work should involve original development or significant advancement of new components, and (2) the project should include a credible plan for integration into an interoperable closed-loop system rather than presenting an isolated device concept with no integration pathway.
What was the intended end state of the technology supported by this FOA?
The target end state described was a wearable and portable system capable of automated operation in real-world conditions, with robust performance outside tightly controlled clinical settings and the ability to support glucose regulation as close to physiological control as possible for individuals living with Type 1 diabetes.
Was the program focused on real-world usability?
Yes. The FOA emphasized wearability, portability, automation, small form factors, and robust performance in everyday life, reflecting interest in systems that can work beyond controlled research environments.
What was the funding instrument and opportunity category?
The funding instrument was a grant, and the opportunity category was discretionary.
Was cost sharing or matching required?
No. The program did not require cost sharing or matching.
How much total funding was estimated for this announcement?
The estimated total funding level for the announcement was $6,000,000.
When was the opportunity posted and when did it close?
The FOA was posted and created on May 14, 2014. The original and current closing date was November 24, 2014.
Is this funding opportunity still open?
No. It was archived on December 25, 2014, which indicates it is no longer open for applications.
What CFDA number is associated with this opportunity?
The CFDA number listed for this opportunity is 93.847, which corresponds to Diabetes, Digestive, and Kidney Diseases Extramural Research.
What types of organizations were eligible to apply?
Eligibility was broad and included state and local governments (including city/township governments, county governments, and special district governments), public housing authorities/Indian housing authorities, public and state-controlled institutions of higher education, private institutions of higher education, independent school districts, nonprofit organizations, and for-profit organizations (including small businesses and for-profit entities other than small businesses).
Were tribal governments and tribal organizations eligible?
Yes. The FOA explicitly included tribal governments (federally recognized and other than federally recognized), tribal organizations, and tribally controlled colleges and universities (TCCUs).
Did the FOA include specific categories of minority-serving institutions?
Yes. It included organizations serving specific communities, such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Alaska Native and Native Hawaiian-serving institutions, and Asian American Native American Pacific Islander-serving institutions (AANAPISIs).
Could faith-based or community-based organizations apply?
Yes. Faith-based and community-based organizations were eligible.
Were non-U.S. (foreign) organizations allowed to participate?
Yes. Foreign organizations and foreign institutions could apply. Non-U.S. components of U.S. organizations were eligible, and foreign components (as defined in the NIH Grants Policy Statement) were allowed.
Did the opportunity require projects to be interoperable with a closed-loop platform?
The summary emphasized a clear path to integration into a functioning closed-loop platform, indicating that proposed components should not be standalone concepts without a plan for interoperability and system-level integration.
Where could applicants find the official full FOA text?
NIH provided an additional information link to the full FOA text hosted on the NIH grants website.
What kind of support contact was mentioned for this opportunity?
NIH listed contact support through the NIH Office of Extramural Research (OER) webmaster email addresses for access issues or linking problems, which is typical for technical assistance rather than scientific program guidance.
Browse more opportunities from the same agency: National Institutes of Health
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Next opportunity: Susan Harwood Training Grant, FY 2014, (Targeted Topics)
Previous opportunity: Diabetes Impact Award Closed Loop Technologies Clinical, Physiological and Behavioral Approaches to Improve Type 1 Diabetes Outcomes (DP3)
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| Polycystic Kidney Disease (PKD) Research and Translation Core Centers (P30) Apply for RFA DK 14 013 Funding Number: RFA DK 14 013 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $750,000 |
| Research Using Biosamples From Selected Type 1 Diabetes Clinical Studies (DP3) Apply for PAR 14 257 Funding Number: PAR 14 257 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $4,000,000 |
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| NIAID SBIR Technology Transfer Direct Phase II (SBIR TT) (R44) Apply for RFA AI 14 049 Funding Number: RFA AI 14 049 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $1,000,000 |
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| Type 1 Diabetes TrialNet Clinical Centers (U01) Apply for RFA DK 14 016 Funding Number: RFA DK 14 016 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $450,000 |
| Prevention of Lower Urinary Tract Symptoms in Women Bladder Health Scientific and Data Coordinating Center (PLUS SDCC) (U01) Apply for RFA DK 14 018 Funding Number: RFA DK 14 018 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $750,000 |
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