Opportunity Information: Apply for W81XWH 11 ALSRP TDA
Apply for W81XWH 11 ALSRP TDA
- The Dept. of the Army USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "DoD Amyotrophic Lateral Sclerosis Therapeutic Development Award" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420 Military Medical Research and Development.
- This funding opportunity was created on Apr 21, 2011 and posted on Apr 21, 2011.
- Applicants must submit their applications by Aug 24, 2011. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $4,800,000.00 to eligible and selected applicants.
- The number of recipients for this funding is limited to 2 candidate(s).
- Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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Opportunity Summary:
The DoD Amyotrophic Lateral Sclerosis (ALS) Therapeutic Development Award is a U.S. Department of the Army (USAMRAA) funding opportunity designed to push potential ALS treatments through the preclinical development stage. The core purpose is to support studies that directly evaluate therapeutic candidates for ALS in a way that is practical and product-focused, with the expectation that the work will generate tangible therapeutic agents and/or preclinical data strong enough to justify and enable the next steps toward new ALS therapies. While projects may be hypothesis-driven, the program emphasis is clearly on therapeutics and preclinical assessment rather than exploratory or purely mechanistic research.
This opportunity was released under Funding Opportunity Number W81XWH-11-ALSRP-TDA and falls within the “Science and Technology and other Research and Development” category. Awards were offered as either cooperative agreements or grants, signaling that projects could be supported through standard grant funding or through a cooperative mechanism where the funder may have more active involvement during the period of performance. The program anticipated making 2 awards, with an estimated total funding level of $4,800,000, indicating a highly competitive competition aimed at a small number of well-developed, execution-ready therapeutic development efforts.
Eligibility was listed as unrestricted, meaning applicants could come from any type of organization (for example, academic institutions, nonprofits, small businesses, large businesses, or other entities), subject to any additional eligibility clarifications that might have appeared in the full announcement text. The opportunity did not require cost sharing or matching funds, reducing financial barriers for applicants and keeping the focus on scientific and development merit.
Key administrative details include a posting and creation date of April 21, 2011, with an original and final closing date of August 24, 2011, and an archive date of September 23, 2011. The relevant CFDA listing was 12.420 (Military Medical Research and Development), which is the federal program classification associated with Department of Defense medical research funding.
For assistance accessing the full announcement, the listed support contact was the CDMRP Help Desk at 301-682-5507. Overall, the award was structured to accelerate credible therapeutic leads for ALS by funding empirical, preclinical, product-oriented studies that can move the field closer to clinical translation and, ultimately, new treatment options for patients.
Frequently Asked Questions (FAQs) - DoD ALS Therapeutic Development Award
What is the DoD Amyotrophic Lateral Sclerosis (ALS) Therapeutic Development Award?
The DoD ALS Therapeutic Development Award is a U.S. Department of the Army (USAMRAA) funding opportunity intended to move potential ALS treatments through the preclinical development stage by supporting practical, product-focused therapeutic evaluation studies.
What is the main purpose of this award?
The core purpose is to fund studies that directly evaluate therapeutic candidates for ALS and generate tangible therapeutic agents and/or preclinical data strong enough to justify and enable the next steps toward new ALS therapies.
What types of projects does this opportunity prioritize?
This opportunity prioritizes therapeutics and preclinical assessment. While projects may be hypothesis-driven, the emphasis is on product-oriented preclinical development work rather than exploratory or purely mechanistic research.
Does the award support exploratory or purely mechanistic ALS research?
Based on the description provided, the program emphasis is not on exploratory or purely mechanistic research. The focus is on practical therapeutic development and preclinical evaluation of ALS treatment candidates.
What stage of research and development is this funding intended to support?
The award is designed to support preclinical development efforts that can produce credible data and/or therapeutic agents suitable to support further translation toward new ALS therapies.
What is the Funding Opportunity Number (FON) for this program?
The Funding Opportunity Number listed is W81XWH-11-ALSRP-TDA.
Which federal category does this opportunity fall under?
The opportunity falls within the category "Science and Technology and other Research and Development."
What funding mechanisms were offered under this opportunity?
Awards were offered as either cooperative agreements or grants.
What is the difference between a grant and a cooperative agreement in this context?
The opportunity indicates that projects could be supported through standard grant funding or through a cooperative mechanism where the funder may have more active involvement during the period of performance.
How many awards were expected to be made?
The program anticipated making 2 awards.
What was the estimated total funding level for this opportunity?
The estimated total funding level was $4,800,000.
What does the anticipated number of awards and funding level suggest about competitiveness?
With an estimated 2 awards and a total of $4,800,000, the competition was positioned as highly competitive and aimed at a small number of well-developed, execution-ready therapeutic development efforts.
Who was eligible to apply?
Eligibility was listed as unrestricted, meaning applicants could come from any type of organization (such as academic institutions, nonprofits, small businesses, large businesses, or other entities), subject to any additional eligibility clarifications that may have been included in the full announcement text.
Was cost sharing or matching funds required?
No. The opportunity did not require cost sharing or matching funds.
When was this funding opportunity posted?
The posting (and creation) date was April 21, 2011.
What was the application deadline?
The original and final closing date was August 24, 2011.
Is this opportunity still open?
No. The opportunity was archived on September 23, 2011, and the final closing date was August 24, 2011.
What is the CFDA number associated with this award?
The CFDA listing provided was 12.420 (Military Medical Research and Development).
Which agency was associated with the funding opportunity?
The opportunity is described as a U.S. Department of the Army (USAMRAA) funding opportunity under the Department of Defense medical research context.
What outcomes or deliverables were expected from funded projects?
Funded work was expected to generate tangible therapeutic agents and/or preclinical data strong enough to justify and enable next steps toward new ALS therapies.
Where can applicants get help accessing the full announcement?
Assistance for accessing the full announcement was available through the CDMRP Help Desk at 301-682-5507.
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Previous opportunity: DoD Amyotrophic Lateral Sclerosis Therapeutic Idea Award
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