Opportunity Information: Apply for W81XWH 11 ALSRP TIA
Apply for W81XWH 11 ALSRP TIA
- The Dept. of the Army USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "DoD Amyotrophic Lateral Sclerosis Therapeutic Idea Award" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420 Military Medical Research and Development.
- This funding opportunity was created on Apr 21, 2011 and posted on Apr 21, 2011.
- Applicants must submit their applications by Aug 24, 2011. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $2,560,000.00 to eligible and selected applicants.
- The number of recipients for this funding is limited to 4 candidate(s).
- Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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Opportunity Summary:
The DoD Amyotrophic Lateral Sclerosis (ALS) Therapeutic Idea Award is a U.S. Department of Defense research funding opportunity aimed at sparking early-stage therapeutic concepts that could open up new directions for treating ALS. It is specifically intended for ideas that are not yet mature but are backed by a strong scientific rationale and can be tested through a clear, well-formed hypothesis. The emphasis is on generating impactful preliminary data and exploring novel avenues that could meaningfully shift the landscape of ALS therapeutics, rather than on incremental work or projects that are already well established.
This award mechanism is positioned as a high risk/high reward program. In practical terms, that means it encourages conceptually innovative projects that may have more uncertainty than conventional proposals, but that could lead to major breakthroughs if successful. The goal is to support research that has the potential to produce critical discoveries or significant advances toward new ALS treatments. Applicants are expected to articulate why the idea is scientifically compelling, what hypothesis is being tested, and how the proposed work could ultimately contribute to therapeutic development for ALS.
Administratively, the opportunity was released under Funding Opportunity Number W81XWH-11-ALSRP-TIA, titled "DoD Amyotrophic Lateral Sclerosis Therapeutic Idea Award," and administered by the Department of the Army through USAMRAA under the broader Military Medical Research and Development program (CFDA 12.420). The funding instrument type listed includes cooperative agreements and grants, and it falls under science and technology and other research and development activities.
The program anticipated making about four awards, with an estimated total funding level of $2,560,000, and it did not require cost sharing or matching funds. Eligibility was described as unrestricted, meaning the competition was broadly open to any applicant entity type, subject to any additional eligibility clarifications that would have appeared in the full announcement. Key dates for this posting show it was originally posted on April 21, 2011, with an application closing date of August 24, 2011, and an archive date of September 23, 2011, indicating it was a time-limited solicitation for that cycle.
For applicant support, the announcement provided a help desk contact for those who could not access the full posting electronically: the CDMRP Help Desk at 301-682-5507.
FAQs: DoD Amyotrophic Lateral Sclerosis (ALS) Therapeutic Idea Award
What is the DoD ALS Therapeutic Idea Award?
The DoD Amyotrophic Lateral Sclerosis (ALS) Therapeutic Idea Award is a U.S. Department of Defense research funding opportunity designed to spark early-stage therapeutic concepts that could open new directions for treating ALS. It prioritizes innovative ideas that are not yet mature, but that have a strong scientific rationale and can be tested through a clear, well-formed hypothesis.
What is the main purpose of this award?
The purpose is to support research that can generate impactful preliminary data and explore novel therapeutic avenues in ALS. The focus is on potentially shifting the ALS therapeutics landscape, rather than supporting incremental work or projects that are already well established.
What types of projects does this award emphasize?
This mechanism emphasizes early-stage, conceptually innovative therapeutic ideas for ALS that may be high uncertainty but are backed by a compelling scientific rationale. Proposed work should be built around a hypothesis that can be tested through a clear plan aimed at producing preliminary data relevant to therapeutic development.
Is this considered a high risk/high reward program?
Yes. The award is positioned as a high risk/high reward program. That means the program encourages novel, potentially breakthrough ideas that may carry more uncertainty than conventional proposals but could lead to major advances if successful.
What does "therapeutic idea" mean in the context of this opportunity?
Based on the description provided, a "therapeutic idea" refers to an early-stage concept intended to contribute toward the development of new ALS treatments. It is expected to be grounded in a strong scientific rationale and structured around a testable hypothesis, with proposed experiments aimed at generating preliminary evidence that supports the direction of a therapeutic approach.
What is the expected outcome of funded work?
Funded work is expected to produce critical discoveries and/or meaningful preliminary data that could significantly advance the path toward new ALS treatments. The emphasis is on opening new avenues rather than extending well-established lines of research.
What kind of scientific framing is expected in an application?
Applicants are expected to explain why the idea is scientifically compelling, clearly state the hypothesis being tested, and describe how the proposed work could ultimately contribute to therapeutic development for ALS. The idea should be testable through a clear, well-formed hypothesis and planned experiments aimed at producing impactful preliminary data.
Does this opportunity support incremental or already well-established projects?
No. The description explicitly emphasizes novel avenues and preliminary data generation over incremental work or projects that are already well established.
What is the Funding Opportunity Number (FON) for this program?
The Funding Opportunity Number is W81XWH-11-ALSRP-TIA.
What is the official title of the funding opportunity?
The title listed is "DoD Amyotrophic Lateral Sclerosis Therapeutic Idea Award."
Which DoD organization administers this opportunity?
The opportunity is administered by the Department of the Army through USAMRAA (U.S. Army Medical Research Acquisition Activity) under the broader Military Medical Research and Development program.
What CFDA number is associated with this award?
The opportunity is listed under CFDA 12.420.
What types of funding instruments are used for awards under this opportunity?
The listed funding instrument types include cooperative agreements and grants.
What broad activity area does this funding fall under?
It falls under science and technology and other research and development activities.
How many awards were anticipated for this cycle?
The program anticipated making about four awards.
What was the estimated total funding level for the program?
The estimated total funding level was $2,560,000.
Is cost sharing or matching funds required?
No. The posting indicated that cost sharing or matching funds were not required.
Who is eligible to apply?
Eligibility was described as unrestricted, meaning the competition was broadly open to any applicant entity type, subject to any additional eligibility clarifications that would have appeared in the full announcement.
When was the opportunity originally posted?
The posting date shown is April 21, 2011.
What was the application closing date?
The application closing date listed is August 24, 2011.
What does the archive date mean for this opportunity?
The archive date is September 23, 2011. Based on the information provided, this indicates it was a time-limited solicitation for that cycle and the posting was later archived.
Where can applicants get help if they cannot access the full posting electronically?
Applicants who could not access the full posting electronically were directed to contact the CDMRP Help Desk at 301-682-5507.
What is the CDMRP Help Desk contact number provided?
The help desk phone number provided is 301-682-5507.
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| Funding Opportunity |
|---|
| DoD Amyotrophic Lateral Sclerosis Therapeutic Development Award Apply for W81XWH 11 ALSRP TDA Funding Number: W81XWH 11 ALSRP TDA Agency: Dept. of the Army USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| DOD FY11 Prostate Cancer Postdoctoral Training Award Apply for W81XWH 11 PCRP PTA Funding Number: W81XWH 11 PCRP PTA Agency: Dept. of the Army USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| DoD FY11 Prostate Cancer Health Disparity Training Award Apply for W81XWH 11 PCRP HDTA Funding Number: W81XWH 11 PCRP HDTA Agency: Dept. of the Army USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| DoD FY11 Prostate Cancer Collaborative Undergraduate HBCU Student Summer Training Program Award Apply for W81XWH 11 PCRP STPA Funding Number: W81XWH 11 PCRP STPA Agency: Dept. of the Army USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| DoD FY11 Prostate Cancer Population Based Research Award Apply for W81XWH 11 PCRP PBRA Funding Number: W81XWH 11 PCRP PBRA Agency: Dept. of the Army USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| DoD FY11 Prostate Cancer Health Disparity Research Award Apply for W81XWH 11 PCRP HDRA Funding Number: W81XWH 11 PCRP HDRA Agency: Dept. of the Army USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| DoD FY11 Prostate Cancer Exploration Hypothesis Development Award Apply for W81XWH 11 PCRP EHDA Funding Number: W81XWH 11 PCRP EHDA Agency: Dept. of the Army USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| DoD FY11 Prostate Cancer Idea Development Award Apply for W81XWH 11 PCRP IDA Funding Number: W81XWH 11 PCRP IDA Agency: Dept. of the Army USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| DoD FY11 Prostate Cancer Synergistic Idea Development Award Apply for W81XWH 11 PCRP SIDA Funding Number: W81XWH 11 PCRP SIDA Agency: Dept. of the Army USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| Tribal Colleges and Universities Program Apply for 11 538 Funding Number: 11 538 Agency: National Science Foundation Category: Science and Technology and other Research and Development Funding Amount: $2,500,000 |
| Software Infrastructure for Sustained Innovation Apply for 11 539 Funding Number: 11 539 Agency: National Science Foundation Category: Science and Technology and other Research and Development Funding Amount: $5,000,000 |
| Research Training Groups in the Mathematical Sciences Apply for 11 540 Funding Number: 11 540 Agency: National Science Foundation Category: Science and Technology and other Research and Development Funding Amount: $500,000 |
| DoD Bone Marrow Failure Idea Award Apply for W81XWH 11 BMFRP IA Funding Number: W81XWH 11 BMFRP IA Agency: Dept. of the Army USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| DoD Bone Marrow Failure Resource Development Award Apply for W81XWH 11 BMFRP RDA Funding Number: W81XWH 11 BMFRP RDA Agency: Dept. of the Army USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| DoD Bone Marrow Failure Postdoctoral Fellowship Award Apply for W81XWH 11 BMFRP POSTDOC Funding Number: W81XWH 11 BMFRP POSTDOC Agency: Dept. of the Army USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| DoD Peer Reviewed Medical Discovery Award Apply for W81XWH 11 PRMRP DA Funding Number: W81XWH 11 PRMRP DA Agency: Dept. of the Army USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| Science and Technology Fellow(s) needed to help agency obtain technical expertise to contribute to more effective application of science and technology in the international development and foreign affairs activities of the U.S. government. Apply for MCC 11 9036 RFA 64 Funding Number: MCC 11 9036 RFA 64 Agency: Millennium Challenge Corporation Category: Science and Technology and other Research and Development Funding Amount: $2,100,000 |
| DoD Peer Reviewed Medical Technology/Therapeutic Development Award Apply for W81XWH 11 PRMRP TTDA Funding Number: W81XWH 11 PRMRP TTDA Agency: Dept. of the Army USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| DoD Peer Reviewed Medical Clinical Trial Award Apply for W81XWH 11 PRMRP CTA Funding Number: W81XWH 11 PRMRP CTA Agency: Dept. of the Army USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| DoD Peer Reviewed Medical Investigator Initiated Research Award Apply for W81XWH 11 PRMRP IIRA Funding Number: W81XWH 11 PRMRP IIRA Agency: Dept. of the Army USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
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