DoD Breast Cancer Concept Award | Apply Online

Opportunity Summary:

The DoD Breast Cancer Concept Award is a funding opportunity under the Department of the Army, administered through the U.S. Army Medical Research Acquisition Activity (USAMRAA), within the Congressionally Directed Medical Research Programs (CDMRP) Breast Cancer Research Program (BCRP). It is designed specifically to seed bold, early-stage breast cancer ideas rather than to extend ongoing projects. The central aim is to support research that tests a highly innovative concept or an unproven theory that could address an important breast cancer problem and potentially open up entirely new directions for the field. In other words, this mechanism is meant for high-risk, high-reward studies where the payoff could be a genuine shift in thinking, even if the approach is not yet supported by conventional evidence.

A defining feature of the Concept Award is that preliminary data are not allowed. Applicants are expected to make their case through a strong scientific rationale and a clear explanation of why the idea is compelling, innovative, and worth testing despite uncertainty. This rule reinforces the program's intent: it is not meant to fund the next logical step of an already established research trajectory, but instead to encourage investigators to propose and test ideas that might be too new, speculative, or unconventional for more traditional grant mechanisms.

There are strict limitations related to human subjects and human biological materials. Because the award is intended for preliminary investigations, studies involving human subjects or human specimens are generally not supported unless they qualify as exempt under Title 32, Code of Federal Regulations, Part 219, Section 101(b) (32 CFR 219.101(b)). Proposals that involve human subjects or specimens and do not meet the exemption criteria will be administratively withdrawn, meaning they will not proceed to funding consideration. For projects using only commercially available, unidentified specimens, the program indicates that a Claim of Exemption Form will be requested, signaling that exemption status must be documented clearly and early.

From the posted announcement information, the funding opportunity number is W81XWH-09-BCRP-CA, titled "DoD Breast Cancer Concept Award." It was offered as a discretionary opportunity using either a cooperative agreement or grant funding instrument, and it falls under the Science and Technology and other Research and Development activity category. The estimated total funding for the opportunity is $10,000,000, with an expected 90 awards, and it does not require cost sharing or matching funds. Eligibility is listed as "unrestricted," meaning it is open to any type of entity, subject to any additional eligibility language in the full announcement. The CFDA number associated with this program is 12.420 (Military Medical Research and Development). Key dates in the notice show a posted and created date of October 1, 2009, an original and current closing date of November 12, 2009, and an archive date of December 12, 2009.

The program also provides context on competitiveness and history: since the Concept Award mechanism began in FY99, it has received 10,081 proposals and recommended 1,073 for funding. That track record communicates both the popularity of the mechanism and the selective nature of awards, while also underscoring the program's long-running emphasis on innovation in breast cancer research.

For applicant support, the announcement lists points of contact for access and submission assistance, including PA HELP at 301-619-7079 (cdmrp.pa@amedd.army.mil), eReceipt HELP at 301-682-5507 (help@cdmrp.org), and the CDMRP Help Desk.

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