Opportunity Information: Apply for W81XWH 12 TSCRP IDA

  • The Dept. of the Army USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "DOD FY12 Tuberous Sclerosis Complex Idea Development Award" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420 Military Medical Research and Development.
  • This funding opportunity was created on Mar 27, 2012 and posted on Mar 22, 2012.
  • Applicants must submit their applications by May 31, 2012. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $2,280,000.00 to eligible and selected applicants.
  • The number of recipients for this funding is limited to 3 candidate(s).
  • Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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Opportunity Summary:

The DOD FY12 Tuberous Sclerosis Complex (TSC) Idea Development Award (Funding Opportunity Number W81XWH-12-TSCRP-IDA) was a U.S. Department of Defense research funding opportunity administered through the Department of the Army, U.S. Army Medical Research Acquisition Activity (USAMRAA), under CFDA 12.420 (Military Medical Research and Development). Its purpose was to support high-impact, innovative research projects that could meaningfully advance the TSC research field, with an emphasis on pushing new ideas forward rather than incremental work.

This award mechanism was intended for science and technology and broader research and development efforts, and it allowed funding through either a grant or a cooperative agreement. The program specifically encouraged preclinical research, signaling an interest in mechanistic studies, proof-of-concept work, model system research, and other non-human or translational efforts that could lay the groundwork for future therapeutic or diagnostic advances. At the same time, the announcement explicitly prohibited clinical trials, meaning applicants could not propose interventional human studies that fit typical clinical trial definitions.

A key application requirement was the inclusion of preliminary data directly relevant to tuberous sclerosis complex and to the proposed research project. In practice, this meant applicants needed to demonstrate some existing evidence supporting feasibility or rationale, such as prior results in cell culture, animal models, patient-derived samples, or other TSC-relevant datasets, rather than submitting purely speculative concepts without supporting data.

The opportunity was broadly open in terms of who could apply. Eligible applicants were listed as unrestricted, meaning it was open to any type of entity, subject to any additional eligibility clarifications that might have appeared in the full announcement. No cost sharing or matching funds were required, which reduced barriers for applicants who might not have institutional or third-party resources to contribute.

From a funding and timing standpoint, the program anticipated making about three awards, with an estimated total funding amount of $2,280,000. The opportunity was posted on March 22, 2012 (created March 27, 2012), and the application deadline was May 31, 2012, with the archive date listed as June 30, 2012. For technical issues accessing the full announcement, applicants were directed to the CDMRP Help Desk (PA HELP and eReceipt HELP) at 301-682-5507 or help@cdmrp.org.

FAQs: DOD FY12 Tuberous Sclerosis Complex (TSC) Idea Development Award (W81XWH-12-TSCRP-IDA)

What is this funding opportunity?

The DOD FY12 Tuberous Sclerosis Complex (TSC) Idea Development Award (Funding Opportunity Number W81XWH-12-TSCRP-IDA) was a U.S. Department of Defense research funding opportunity to support high-impact, innovative projects intended to meaningfully advance the tuberous sclerosis complex research field.

Which agency administered the program?

The opportunity was administered through the Department of the Army, U.S. Army Medical Research Acquisition Activity (USAMRAA).

What CFDA number is associated with this opportunity?

The opportunity was listed under CFDA 12.420 (Military Medical Research and Development).

What was the main purpose of the Idea Development Award?

The purpose was to support high-impact, innovative research projects, with an emphasis on pushing new ideas forward rather than funding incremental work.

What kind of research did the program aim to fund?

The mechanism was intended for science and technology and broader research and development efforts. The announcement specifically encouraged preclinical research, including mechanistic studies, proof-of-concept work, and model system research, as well as other non-human or translational efforts that could lay groundwork for future therapeutic or diagnostic advances.

Were clinical trials allowed under this opportunity?

No. The announcement explicitly prohibited clinical trials, meaning applicants could not propose interventional human studies that fit typical clinical trial definitions.

Was preliminary data required?

Yes. A key application requirement was the inclusion of preliminary data directly relevant to tuberous sclerosis complex and to the proposed project.

What did "preliminary data directly relevant to TSC" mean in practice?

Applicants needed to show existing evidence supporting feasibility or rationale (for example, prior results in cell culture, animal models, patient-derived samples, or other TSC-relevant datasets), rather than submitting purely speculative concepts without supporting data.

What funding instruments were available?

Funding could be provided through either a grant or a cooperative agreement.

Who was eligible to apply?

Eligible applicants were listed as unrestricted, meaning the opportunity was broadly open to any type of entity, subject to any additional eligibility clarifications that might have been included in the full announcement.

Was cost sharing or matching required?

No. The opportunity stated that no cost sharing or matching funds were required.

How many awards were expected to be made?

The program anticipated making about three awards.

What was the estimated total amount of funding available?

The estimated total funding amount was $2,280,000.

When was the opportunity posted?

The opportunity was posted on March 22, 2012 (created March 27, 2012).

What was the application deadline?

The application deadline was May 31, 2012.

When was the archive date for the opportunity?

The archive date was listed as June 30, 2012.

Where could applicants get help with technical issues accessing the full announcement?

Applicants were directed to the CDMRP Help Desk (PA HELP and eReceipt HELP) at 301-682-5507 or help@cdmrp.org for technical issues accessing the full announcement.

What was the program emphasis: incremental advances or new directions?

The emphasis was on innovative, high-impact work and pushing new ideas forward, rather than incremental research.

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