Opportunity Information: Apply for W81XWH 14 LCRP CDA

  • The Dept. of the Army USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "DoD Lung Cancer Career Development Award" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420 Military Medical Research and Development.
  • This funding opportunity was created on Apr 14, 2014 and posted on Apr 14, 2014.
  • Applicants must submit their applications by Sep 17, 2014. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $1,152,000.00 to eligible and selected applicants.
  • The number of recipients for this funding is limited to 3 candidate(s).
  • Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
Apply for W81XWH 14 LCRP CDA

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Opportunity Summary:

The DoD Lung Cancer Career Development Award (Funding Opportunity Number W81XWH-14-LCRP-CDA) is a Department of the Army USAMRAA funding opportunity under the Lung Cancer Research Program designed to help launch the next generation of independent lung cancer investigators. Its central goal is to support early-career research or physician scientists as they lead an impactful, discovery-focused research project while receiving structured mentorship from an established lung cancer researcher. The award is positioned as both a research grant and a career-building mechanism, offering funding, mentoring, and guided professional development intended to help recipients become productive, independent leaders in lung cancer research.

A defining feature of this opportunity is that it targets investigators who are still early in their independent careers, specifically those within five years of their first faculty appointment (or an equivalent position). Applicants need to show a strong commitment to building a long-term career in lung cancer research, not simply completing a single project. The program emphasizes that preliminary data is not required, which lowers a common barrier for newer investigators, but it still expects proposals to be grounded in logical reasoning, clear scientific rationale, and a credible approach to achieving meaningful results. In other words, the application must make a strong case that the ideas are sound and that the work could plausibly generate important discoveries even if the applicant is not arriving with an extensive dataset.

Mentorship is not a minor administrative requirement in this award; it is one of the main pillars. Each applicant must identify a mentor who is an experienced lung cancer researcher with a demonstrated track record of funding and publications in lung cancer. Beyond credentials, the mentor must show an active commitment to the applicant's career development, reflecting the program's intention that awardees gain more than money. The mentor relationship is meant to provide guidance on scientific direction, professional growth, and the practical steps involved in establishing an independent research trajectory in lung cancer.

Because the focus is career development, applicants must include a Career Development Plan prepared with input from the mentor. This plan is expected to be concrete and forward-looking, describing how the principal investigator will acquire the skills, expertise, and experiences needed to operate at the forefront of lung cancer research. It should address training and professional development in a way that is integrated with the proposed research, rather than treated as an add-on. The applicant's institution must also formally support this development by guaranteeing at least 40 percent protected time for the investigator to conduct the proposed research, with the announcement noting that more protected time is highly desirable. This protected time requirement signals that the program is trying to ensure awardees have real capacity to build momentum, publish, and mature scientifically rather than juggling responsibilities that would stall progress.

The research itself is expected to aim for high potential impact, with the program explicitly prioritizing projects that could drive major advances and accelerate progress toward reducing deaths from lung cancer. While the opportunity encourages discovery-oriented work, the emphasis on impact indicates that reviewers are likely to value proposals that can clearly explain why the question matters, what new knowledge could result, and how those discoveries might ultimately change understanding, prevention, diagnosis, or treatment approaches in lung cancer. Applicants are also strongly encouraged to collaborate with or submit proposals involving Military Treatment Facilities, military laboratories, and Department of Veterans Affairs medical centers and research labs, underscoring the DoD interest in connecting funded research with military and veteran health systems and research environments.

Another required thread throughout the application is relevance to military beneficiaries. Proposals must clearly articulate how the work relates to service members, veterans, their families, and other military beneficiaries. This does not necessarily mean the research must be conducted exclusively in military settings, but it does mean the investigator needs to explain the connection between the scientific work and the health needs or exposures relevant to military populations, including why the knowledge gained could matter for those communities.

Administratively, this opportunity was posted April 14, 2014, with an original and current closing date of September 17, 2014, and an archive date of October 17, 2014. It is categorized as discretionary funding and supports awards through cooperative agreements and grants under CFDA 12.420 (Military Medical Research and Development). The estimated total funding listed is $1,152,000 with an expected three awards, and there is no cost-sharing or matching requirement. Eligibility is described as unrestricted, meaning it is open to any type of entity unless additional eligibility text in the full announcement adds clarifications. For access issues or submission support, the CDMRP Help Desk is listed as a contact point (phone 301-682-5507; email help@eBRAP.org).

DoD Lung Cancer Career Development Award (W81XWH-14-LCRP-CDA) FAQs

What is the DoD Lung Cancer Career Development Award (CDA)?

The DoD Lung Cancer Career Development Award (Funding Opportunity Number W81XWH-14-LCRP-CDA) is a Department of the Army USAMRAA funding opportunity under the Lung Cancer Research Program. It is intended to help launch the next generation of independent lung cancer investigators by supporting an impactful, discovery-focused research project paired with structured mentorship and guided professional development.

What is the main goal of this award?

The central goal is to support early-career research or physician scientists as they lead a high-impact lung cancer research project while building independence through structured mentorship and a career development framework. The award is positioned as both a research grant and a career-building mechanism.

Who is the award designed to support?

The program targets investigators who are still early in their independent careers, specifically those within five years of their first faculty appointment (or an equivalent position). Applicants are expected to demonstrate commitment to building a long-term career in lung cancer research, not just completing a single project.

How does the award define "early-career" eligibility?

Based on the opportunity description provided, the award is aimed at investigators within five years of their first faculty appointment (or an equivalent position).

Is preliminary data required to apply?

No. The opportunity emphasizes that preliminary data is not required. However, the proposal must still be grounded in logical reasoning, a clear scientific rationale, and a credible approach that could plausibly generate meaningful discoveries.

What kind of research does the award prioritize?

The research is expected to be discovery-oriented and high-impact, with the program prioritizing projects that could drive major advances and accelerate progress toward reducing deaths from lung cancer. Reviewers are likely to value proposals that clearly explain why the question matters, what new knowledge could result, and how the discoveries might ultimately influence understanding, prevention, diagnosis, or treatment approaches.

Is mentorship required, or is it optional?

Mentorship is required and is described as a main pillar of the award rather than an administrative formality. Each applicant must identify a mentor who is an experienced lung cancer researcher and who actively commits to the applicant's career development.

What qualifications must the mentor have?

The mentor must be an established lung cancer researcher with a demonstrated track record of funding and publications in lung cancer, and must show active commitment to supporting the applicant's scientific direction, professional growth, and path toward an independent research career.

What is the Career Development Plan, and is it required?

A Career Development Plan is required and must be prepared with input from the mentor. It is expected to be concrete and forward-looking, describing how the principal investigator will acquire skills, expertise, and experiences needed to operate at the forefront of lung cancer research, and it should be integrated with the proposed research rather than treated as an add-on.

Does the applicant's institution need to provide protected time?

Yes. The institution must formally support the applicant's development by guaranteeing at least 40 percent protected time for the investigator to conduct the proposed research. The opportunity notes that more protected time is highly desirable.

Why does the award require protected time?

The protected time requirement is intended to ensure awardees have real capacity to build momentum, publish, and mature scientifically, rather than having competing responsibilities that could stall progress during this career-building period.

Are collaborations with military or veterans health systems encouraged?

Yes. Applicants are strongly encouraged to collaborate with or submit proposals involving Military Treatment Facilities, military laboratories, and Department of Veterans Affairs medical centers and research labs.

What does "relevance to military beneficiaries" mean for the application?

Proposals must clearly articulate how the work relates to service members, veterans, their families, and other military beneficiaries. The research does not need to be conducted exclusively in military settings, but the application must explain the connection between the scientific work and the health needs or exposures relevant to military populations, and why the knowledge gained could matter for those communities.

Which agency and program are associated with this opportunity?

This is a Department of the Army USAMRAA opportunity under the Lung Cancer Research Program (Lung Cancer Research Program, LCRP) and is associated with the DoD Congressionally Directed Medical Research Programs (CDMRP) ecosystem (as reflected by the listed CDMRP Help Desk contact).

What is the funding mechanism for this award?

The opportunity supports awards through cooperative agreements and grants.

What is the CFDA number for this program?

The opportunity is listed under CFDA 12.420 (Military Medical Research and Development).

Is there a cost-sharing or matching requirement?

No. The opportunity states there is no cost-sharing or matching requirement.

How much total funding is estimated, and how many awards are expected?

The estimated total funding is $1,152,000, with an expected three awards.

What is the eligibility for entities applying?

Eligibility is described as unrestricted, meaning it is open to any type of entity, unless additional eligibility text in the full announcement provides further clarifications.

What are the key dates for this funding opportunity?

The opportunity was posted on April 14, 2014. The original and current closing date is September 17, 2014. The archive date is October 17, 2014.

Who can applicants contact for submission help or access issues?

The CDMRP Help Desk is listed as the support contact point: phone 301-682-5507; email help@eBRAP.org.

What is the overall expectation for applicants beyond the research project itself?

Applicants are expected to show strong commitment to establishing a long-term lung cancer research career, develop a credible and impactful discovery-focused project, engage in structured mentorship, and follow an integrated Career Development Plan supported by institutional protected time.

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