DoD Lung Cancer Idea Development Award | Apply Online

Opportunity Summary:

The DoD Lung Cancer Research Program (LCRP) Idea Development Award is a Department of the Army (USAMRAA) funding opportunity designed to push forward early-stage, conceptually new lung cancer research ideas that are not yet fully developed but have strong potential to open up important new directions. The program explicitly targets high risk, high reward projects that could generate impactful data, lead to critical discoveries, or create major advances that speed progress toward the long-term goal of eliminating deaths from lung cancer. While the work can be exploratory, applications are expected to be grounded in a well-formulated, testable hypothesis supported by a clear scientific rationale.

A central theme of this award is innovation paired with potential impact. Innovation, as the program defines it, can mean introducing a new paradigm, challenging existing assumptions, or approaching an old problem from a genuinely new angle. Impact is framed as the likelihood that the work could materially change the field or significantly accelerate progress against lung cancer mortality. Because of that emphasis, applicants are expected to explicitly spell out what is novel about the concept and why it matters, including how the project could influence lung cancer research and, ultimately, patients, even if a direct clinical deliverable is not immediate.

The opportunity also highlights relevance to military beneficiaries and strongly encourages collaboration or partnership with military- and veteran-focused research environments. Submissions involving investigators at Military Treatment Facilities (MTFs), military laboratories, and Department of Veterans Affairs (VA) Medical Centers and research laboratories are particularly encouraged. This signals that proposals should, where applicable, connect the research problem to the needs of service members, veterans, and their families, and that the DoD values projects that can leverage those clinical populations, infrastructures, or research strengths.

A notable feature is a dedicated track for New Investigators. For this announcement, New Investigators are generally described as independent researchers within 10 years of their first faculty appointment (or equivalent). New Investigator applications are reviewed separately from those led by established investigators, giving earlier-career faculty a more comparable competitive pool. At the same time, the announcement makes it clear that New Investigators are strongly encouraged to collaborate with researchers who have lung cancer expertise or other specialized capabilities needed for the project. Applicants must explain how any collaboration fills gaps and strengthens the principal investigator’s ability to answer the proposed research question, and they must meet specific eligibility criteria referenced in the announcement.

Unlike some early-concept programs that allow purely speculative ideas, this award requires preliminary data to demonstrate feasibility of the hypothesis and approach. However, the preliminary data do not have to be generated in lung cancer specifically, which creates space for researchers bringing tools, models, or insights from other diseases or disciplines as long as they can credibly justify how those foundations translate into a feasible lung cancer study.

From an administrative and funding standpoint, this was a discretionary funding opportunity with funding instruments listed as cooperative agreement and grant under the science and technology/research and development category. It carried no cost sharing or matching requirement. The opportunity (Funding Opportunity Number W81XWH-14-LCRP-IDA; CFDA 12.420 Military Medical Research and Development) anticipated making about 6 awards from an estimated total funding pool of $3,360,000. Eligibility was listed as unrestricted (open broadly to entity types), subject to any additional eligibility clarifications in the full announcement. The posting date was April 14, 2014, with an original and final closing date of September 17, 2014, and an archive date of October 17, 2014.

For applicants, the practical takeaway is that this mechanism is meant for bold, hypothesis-driven projects that are still early but not premature: the idea should be genuinely new, supported by enough preliminary evidence to show it can be tested, and presented with a clear argument for why it could meaningfully move the needle on lung cancer outcomes. Strong proposals will usually make the innovation easy to see, link the expected scientific payoff to patient or field-level impact, and clearly state why the work matters for military-connected populations, ideally strengthened through partnerships with MTF, VA, or military research investigators or sites. For help accessing the full announcement, the notice directs applicants to the CDMRP Help Desk (help@eBRAP.org; 301-682-5507).

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