Opportunity Information: Apply for W81XWH 15 LCRP CDA

  • The Dept. of the Army USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "DoD Lung Cancer Career Development Award" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420 Military Medical Research and Development.
  • This funding opportunity was created on Apr 8, 2015 and posted on Apr 8, 2015.
  • Applicants must submit their applications by Sep 16, 2015. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $1,152,000.00 to eligible and selected applicants.
  • The number of recipients for this funding is limited to 3 candidate(s).
  • Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
Apply for W81XWH 15 LCRP CDA

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Opportunity Summary:

The DoD Lung Cancer Career Development Award (Funding Opportunity Number W81XWH-15-LCRP-CDA) is a Department of the Army, USAMRAA funding opportunity designed to help early career investigators launch strong, independent research careers focused on lung cancer. The program centers on pairing an emerging principal investigator with an established lung cancer researcher who can provide hands-on mentorship while the investigator conducts a discovery-oriented research project with the potential to meaningfully move the field forward. While the award supports a specific research plan, its broader purpose is career building: giving promising scientists the time, resources, and guidance needed to become long-term leaders in lung cancer research.

This award is aimed at early-stage, independent researchers who are either research scientists or physician-scientists. Eligibility is tied to career timing: the principal investigator must be within five years of their first faculty appointment or an equivalent independent position. The opportunity is meant for people who have already taken the step into independence but are still early enough in their careers that structured mentorship and protected research time can strongly shape their trajectory. Applicants are expected to show a clear commitment to remaining in lung cancer research as a primary career focus rather than treating the project as a one-off study.

Mentorship is a required pillar of the application rather than an optional feature. The designated mentor must be an experienced lung cancer researcher with a strong track record that is visible in both sustained research funding and peer-reviewed publications specifically relevant to lung cancer. Beyond credentials, the mentor is expected to demonstrate genuine commitment to developing the principal investigator, meaning the relationship should be substantive and intentional. In practice, the application should make it clear how the mentor will contribute to scientific direction, professional development, and the investigator's transition to a fully independent program.

A formal Career Development Plan is also required and should be built jointly by the investigator and mentor. This plan needs to spell out a realistic strategy for building the skills, expertise, and scientific maturity needed to work at the forefront of lung cancer research. It should describe the training and experiences the investigator will pursue during the award period, such as learning new methodologies, strengthening translational or clinical research skills, expanding leadership and grantsmanship capabilities, or building collaborations that support long-term independence. Because career development is the core goal, the applicant's institution must show tangible support by guaranteeing at least 40 percent protected time for the investigator to conduct the proposed research, with the announcement emphasizing that more protected time is strongly preferred.

The research itself is expected to be impactful, with a stated emphasis on discovery. The program is looking for projects that have high potential to change understanding of lung cancer or open paths that could ultimately drive major advances, rather than incremental work. Applicants should frame their research aims in terms of how the outcomes could significantly accelerate progress toward reducing and ultimately preventing deaths from lung cancer, even if the project is not immediately clinical in nature.

A defining requirement is relevance to military beneficiaries. Applications must clearly explain why the research matters to Service members, Veterans, and their families. In addition, the program strongly encourages submissions from investigators at, or partnerships involving, military treatment facilities, military laboratories, and Department of Veterans Affairs medical centers and research labs. This encouragement signals that the program values projects grounded in military and Veteran health needs, access to those patient populations or data sources, and collaborations that strengthen the connection between lung cancer science and the unique exposures, risks, or care settings seen in military communities.

Administratively, the opportunity was posted April 8, 2015, with an original and current closing date of September 16, 2015, and an archive date of October 16, 2015. It was offered as a grant or cooperative agreement under CFDA 12.420 (Military Medical Research and Development), with no cost sharing or matching requirement. The estimated total funding amount was $1,152,000, with an expected three awards, and eligibility was listed as unrestricted, meaning it was broadly open to applicant organizations subject to any clarifications in the full announcement. For technical assistance accessing the full announcement, the listed help desk contact was eBRAP (phone 301-682-5507, email help@eBRAP.org).

DoD Lung Cancer Career Development Award (W81XWH-15-LCRP-CDA) FAQs

1) What is the DoD Lung Cancer Career Development Award?

The DoD Lung Cancer Career Development Award (Funding Opportunity Number W81XWH-15-LCRP-CDA) is a Department of the Army, USAMRAA funding opportunity intended to help early career investigators build strong, independent research careers focused on lung cancer. It supports a discovery-oriented research project, but the larger goal is career development through mentorship, protected research time, and structured training.

2) What is the main purpose of this award?

The award is designed to launch or strengthen an early-stage independent investigator's long-term trajectory in lung cancer research. While it funds a specific research plan, it emphasizes career building, including mentorship and a formal Career Development Plan to help the investigator progress toward leading an independent lung cancer research program.

3) Who is this funding opportunity intended for?

This opportunity is aimed at early-stage, independent researchers, including research scientists and physician-scientists, who are building an independent career in lung cancer research and want structured mentorship and protected time to accelerate their development.

4) What does "early career" mean for eligibility?

The principal investigator (PI) must be within five years of their first faculty appointment or an equivalent independent position. The program is meant for investigators who have already transitioned into independence but are still early enough in their careers that mentorship and protected time can make a major difference.

5) Does the award expect applicants to stay in lung cancer research long term?

Yes. Applicants are expected to demonstrate a clear commitment to lung cancer research as a primary career focus, rather than treating the proposed project as a one-time study unrelated to their long-term research direction.

6) Is mentorship required, or optional?

Mentorship is a required part of the application. The program centers on pairing an emerging PI with an established lung cancer researcher who provides hands-on mentorship during the award period.

7) What qualifications must the mentor have?

The mentor must be an experienced lung cancer researcher with a strong track record that is demonstrated through sustained research funding and peer-reviewed publications specifically relevant to lung cancer. The application should also show the mentor's genuine commitment to developing the PI.

8) What is the mentor expected to do during the award?

Based on the announcement description, the mentor should contribute in meaningful, practical ways to the PI's scientific direction, professional development, and transition to a fully independent research program. The relationship is expected to be substantive and intentional, not nominal.

9) Is a Career Development Plan required?

Yes. A formal Career Development Plan is required and should be built jointly by the PI and the mentor. This plan should describe a realistic strategy for building the PI's skills and scientific maturity to work at the forefront of lung cancer research.

10) What should be included in the Career Development Plan?

The plan should outline training and experiences the PI will pursue during the award period. Examples mentioned include learning new methodologies, strengthening translational or clinical research skills, expanding leadership and grantsmanship capabilities, and building collaborations that support long-term independence.

11) What institutional support is required for the PI?

The PI's institution must show tangible support by guaranteeing at least 40 percent protected time for the PI to conduct the proposed research. The announcement emphasizes that more protected time is strongly preferred.

12) What kind of research does this award support?

The program supports discovery-oriented lung cancer research with the potential to meaningfully move the field forward. The emphasis is on impactful work that could change understanding of lung cancer or open new paths toward major advances, rather than incremental projects.

13) Does the research need to be immediately clinical?

Not necessarily. The research should be framed in terms of how outcomes could significantly accelerate progress toward reducing and ultimately preventing deaths from lung cancer, even if the project is not immediately clinical in nature.

14) How important is relevance to military beneficiaries?

It is a defining requirement. Applications must clearly explain why the research matters to Service members, Veterans, and their families.

15) Are collaborations with military or VA organizations encouraged?

Yes. The program strongly encourages submissions from investigators at, or partnerships involving, military treatment facilities, military laboratories, and Department of Veterans Affairs medical centers and research labs.

16) Why does the opportunity emphasize military and Veteran relevance?

The announcement indicates the program values projects grounded in military and Veteran health needs, including the unique exposures, risks, and care settings relevant to military communities, and collaborations that strengthen the connection between lung cancer science and those populations.

17) What type of funding mechanism is used?

The opportunity was offered as a grant or cooperative agreement.

18) What CFDA number is associated with this opportunity?

The CFDA number listed is 12.420 (Military Medical Research and Development).

19) Is cost sharing or matching required?

No. The announcement states there is no cost sharing or matching requirement.

20) How much total funding was estimated, and how many awards were expected?

The estimated total funding amount was $1,152,000, with an expected three awards.

21) Was eligibility restricted?

Eligibility was listed as unrestricted, meaning it was broadly open to applicant organizations, subject to any clarifications in the full announcement.

22) When was the opportunity posted and when did it close?

The opportunity was posted on April 8, 2015. The original and current closing date was September 16, 2015. The archive date was October 16, 2015.

23) Who can help if we need technical assistance accessing the full announcement?

The listed help desk contact for technical assistance was eBRAP. Phone: 301-682-5507. Email: help@eBRAP.org.

24) What makes a competitive application based on the description provided?

Based on the information provided, competitiveness is tied to: (a) a strong mentorship pairing with an established lung cancer researcher; (b) a clear, jointly developed Career Development Plan; (c) strong institutional commitment including at least 40 percent protected time (more preferred); (d) a discovery-focused project with high potential impact rather than incremental progress; and (e) a clear explanation of relevance to Service members, Veterans, and their families, with military/VA collaborations encouraged.

25) Where can applicants find the official opportunity identifier?

The funding opportunity number provided is W81XWH-15-LCRP-CDA.

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