Opportunity Information: Apply for W81XWH 13 MSRP IDA

  • The Dept. of the Army USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "DoD Multiple Sclerosis Idea Development Award" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420 Military Medical Research and Development.
  • This funding opportunity was created on May 3, 2013 and posted on May 3, 2013.
  • Applicants must submit their applications by Sep 17, 2013. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $3,240,000.00 to eligible and selected applicants.
  • The number of recipients for this funding is limited to 5 candidate(s).
  • Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
Apply for W81XWH 13 MSRP IDA

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Opportunity Summary:

The DoD Multiple Sclerosis Research Program (MSRP) Idea Development Award is a competitive funding opportunity from the Department of the Army (USAMRAA) designed to move bold, early-stage multiple sclerosis (MS) ideas toward meaningful breakthroughs. The intent is to support projects that are not yet fully mature but are grounded in a clear, testable hypothesis and strong scientific rationale. The program is aimed at conceptually innovative work that could open entirely new avenues of investigation, lead to critical discoveries about the causes and progression of MS, and/or generate improvements in patient care and quality of life.

A central theme of this award is innovation, specifically research that changes how people think about MS rather than simply extending existing work. Proposals are expected to introduce a new paradigm, challenge established assumptions, or approach a persistent MS problem from a truly different angle. The award explicitly favors high risk, high reward concepts as long as there is a credible path to major impact. Incremental studies described as the next logical step from prior findings are not considered innovative enough for this mechanism and are not expected to be competitive.

Impact is the other major pillar. To be responsive, the proposed project must address at least one of the FY13 MSRP Focus Areas (the specific list is referenced in the full announcement). Applicants are expected to explain both the near-term value of the work (what the study will deliver during the project period) and the longer-term implications (how the results could shift MS research directions, clarify mechanisms of disease initiation or progression, or translate into better clinical management and quality of life outcomes). The program is looking for research that, if successful, would substantially advance the field rather than produce narrow or modest gains.

While the mechanism targets early-stage ideas, preliminary support for the concept is encouraged. Applicants may include preliminary data when available, including unpublished results from the principal investigator or named collaborators, as well as relevant published findings that support feasibility and rationale. The emphasis is not that a large dataset is required, but that the application should make a scientifically convincing case that the hypothesis is worth testing and that the approach has a reasonable chance of producing informative results.

Administratively, this opportunity was posted May 3, 2013 under Funding Opportunity Number W81XWH-13-MSRP-IDA, with an original and final closing date of September 17, 2013 (archived October 17, 2013). The program anticipated making about 5 awards with an estimated total funding level of $3,240,000. The funding instrument type is listed as a grant or cooperative agreement under the CFDA number 12.420 (Military Medical Research and Development). Cost sharing or matching was not required, and eligibility was described as unrestricted (open to any type of applicant entity, subject to any additional eligibility clarifications in the full text of the announcement). For access issues or announcement assistance, the contact listed is the CDMRP Help Desk at 301-682-5507.

Frequently Asked Questions (FAQs)

What is the DoD Multiple Sclerosis Research Program (MSRP) Idea Development Award?

The MSRP Idea Development Award is a competitive funding opportunity administered by the U.S. Army Medical Research Acquisition Activity (USAMRAA) under the Department of the Army. It is designed to move bold, early-stage multiple sclerosis (MS) research ideas toward meaningful breakthroughs.

What is the main goal of this award mechanism?

The main goal is to support conceptually innovative, early-stage MS research that is not yet fully mature but is grounded in a clear, testable hypothesis and strong scientific rationale. The expectation is that successful projects could substantially advance the MS field rather than produce modest or narrowly incremental gains.

What types of research ideas are considered a strong fit?

Projects are expected to be conceptually innovative and capable of changing how people think about MS. Strong fits include research that introduces a new paradigm, challenges established assumptions, or approaches a persistent MS problem from a genuinely different angle, with a credible path to major impact.

Does the program encourage high-risk, high-reward research?

Yes. The award explicitly favors high risk, high reward concepts, as long as the application presents a scientifically convincing rationale and a credible path to major impact if the work succeeds.

Are incremental or follow-on studies competitive under this award?

Generally no. The award emphasizes innovation, and incremental studies described as the next logical step from prior findings are not considered innovative enough for this mechanism and are not expected to be competitive.

What are the core review pillars emphasized in the opportunity description?

Two major pillars are emphasized: innovation and impact. Proposals should demonstrate genuine conceptual innovation and also explain how the work would matter for the MS field and/or patient outcomes if successful.

Does the proposed project need to align with specific program priorities?

Yes. To be responsive, the project must address at least one of the FY13 MSRP Focus Areas. The specific list of focus areas is referenced in the full announcement.

How should applicants describe impact in their applications?

Applicants are expected to explain both near-term value (what the study will deliver during the project period) and longer-term implications (how results could shift MS research directions, clarify mechanisms of disease initiation or progression, or translate into better clinical management, patient care, and quality of life).

Is preliminary data required?

Preliminary support for the concept is encouraged, but the emphasis is not that a large dataset is required. The application should make a scientifically convincing case that the hypothesis is worth testing and that the approach has a reasonable chance of producing informative results.

What kinds of preliminary support can be included?

Applicants may include preliminary data when available, including unpublished results from the principal investigator or named collaborators, as well as relevant published findings that support feasibility and scientific rationale.

What is the funding opportunity number for this announcement?

The Funding Opportunity Number is W81XWH-13-MSRP-IDA.

When was this opportunity posted and when did it close?

It was posted on May 3, 2013. The original and final closing date was September 17, 2013. The opportunity was archived on October 17, 2013.

How many awards were anticipated and what was the estimated total funding level?

The program anticipated making about 5 awards, with an estimated total funding level of $3,240,000.

What type of funding instrument does this opportunity use?

The funding instrument type is listed as a grant or cooperative agreement.

What is the CFDA number associated with this program?

The CFDA number is 12.420, labeled as Military Medical Research and Development.

Is cost sharing or matching required?

No. Cost sharing or matching was not required for this opportunity.

Who was eligible to apply?

Eligibility was described as unrestricted, meaning it was open to any type of applicant entity, subject to any additional eligibility clarifications in the full text of the announcement.

Who can applicants contact for help accessing the announcement or for technical issues?

The contact listed for access issues or announcement assistance is the CDMRP Help Desk at 301-682-5507.

Which organization administered this funding opportunity?

The opportunity is described as coming from the Department of the Army (USAMRAA) under the Department of Defense Multiple Sclerosis Research Program (MSRP).

What kinds of outcomes is the program ultimately trying to enable?

The program seeks research that could lead to critical discoveries about the causes and progression of MS and/or generate improvements in patient care and quality of life, including work that could shift research directions or inform better clinical management.

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