Opportunity Information: Apply for W81XWH 15 NFRP EHDA
Apply for W81XWH 15 NFRP EHDA
- The Dept. of the Army USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "DoD Neurofibromatosis Exploration Hypothesis Development Award" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420 Military Medical Research and Development.
- This funding opportunity was created on May 6, 2015 and posted on May 6, 2015.
- Applicants must submit their applications by Jul 27, 2015. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $1,280,000.00 to eligible and selected applicants.
- The number of recipients for this funding is limited to 8 candidate(s).
- Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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Opportunity Summary:
The DoD Neurofibromatosis Exploration - Hypothesis Development Award is a U.S. Department of Defense research funding opportunity under the Neurofibromatosis Research Program (NFRP) that is meant to jump-start bold, early-stage ideas in neurofibromatosis (NF) research. Its core purpose is to support the initial exploration of innovative, high-risk, high-gain concepts that could be genuinely groundbreaking, with the expectation that the resulting findings will create a foundation for new lines of investigation and position teams to pursue larger, follow-on studies later. In practice, this award is aimed at enabling researchers to test a strong, well-reasoned scientific idea that might be too preliminary or unconventional for more conservative funding mechanisms, so long as the hypothesis is clearly stated, testable, and backed by solid rationale and a credible study design.
A key feature of this opportunity is its emphasis on true innovation rather than incremental progress. Proposed projects should go beyond small extensions of existing published work. Competitive applications are expected to either introduce a new paradigm, challenge prevailing assumptions, address persistent NF problems from a fresh angle, or otherwise show a high degree of creativity and originality. While preliminary data and published supporting evidence are encouraged as they can strengthen confidence in feasibility, they are not required, which reinforces the program's intent to fund exploratory work that is still forming but scientifically defensible. Because innovation is central to the award, the Principal Investigator is expected to explicitly explain what makes the project innovative within the NF field, rather than assuming reviewers will infer novelty on their own.
Administratively, this opportunity was offered by the Department of the Army through the U.S. Army Medical Research Acquisition Activity (USAMRAA) and is categorized under Science and Technology and other Research and Development. The funding opportunity number is W81XWH-15-NFRP-EHDA, and the CFDA listing associated with it is 12.420 (Military Medical Research and Development). The instrument type listed includes grants and cooperative agreements, and the program anticipated making about eight awards with an estimated total funding level of $1,280,000. There was no cost sharing or matching requirement, which means applicants were not expected to contribute their own funds as a condition of receiving the award.
Eligibility was described as unrestricted, meaning it was open to essentially any type of entity, subject to any additional eligibility clarifications contained in the full announcement. The posting date and creation date were May 6, 2015, with an original and current closing date of July 27, 2015, and an archive date of August 26, 2015. For applicants who had trouble accessing the full announcement, the contact point provided was the CDMRP Help Desk at 301-682-5507. Overall, the opportunity is best understood as a catalyst program: it is designed to fund carefully conceived, hypothesis-driven NF research that is willing to take informed risks in pursuit of outsized advances, while requiring applicants to clearly demonstrate how their approach breaks new ground.
Frequently Asked Questions (FAQs)
What is the DoD Neurofibromatosis Exploration - Hypothesis Development Award?
The DoD Neurofibromatosis Exploration - Hypothesis Development Award is a U.S. Department of Defense research funding opportunity under the Neurofibromatosis Research Program (NFRP). It is intended to jump-start bold, early-stage ideas in neurofibromatosis (NF) research by supporting the initial exploration of innovative, high-risk, high-gain concepts.
What is the main purpose of this award?
The core purpose is to fund the early testing of genuinely innovative and potentially groundbreaking hypotheses in NF research. The expectation is that the results will create a foundation for new lines of investigation and help position the research team to pursue larger, follow-on studies later.
What types of projects are a good fit for this opportunity?
This award is aimed at projects that test a strong, well-reasoned scientific idea that may be too preliminary or unconventional for more conservative funding mechanisms. Proposed work should be hypothesis-driven, clearly stated, testable, backed by solid rationale, and supported by a credible study design.
How important is innovation for this award?
Innovation is central. The opportunity emphasizes true innovation rather than incremental progress. Competitive applications are expected to go beyond small extensions of existing published work and instead introduce a new paradigm, challenge prevailing assumptions, or tackle persistent NF problems from a fresh angle.
Are incremental extensions of existing published work competitive?
Projects that are primarily small extensions of existing published work are not the intended focus. The award is designed to prioritize creativity, originality, and approaches that clearly break new ground in the NF field.
Is preliminary data required to apply?
No. Preliminary data and published supporting evidence are encouraged because they can strengthen confidence in feasibility, but they are not required. This reflects the program intent to fund exploratory work that is still forming but scientifically defensible.
If preliminary data is not required, what must be clearly demonstrated?
The application should still present a clearly stated and testable hypothesis, a solid scientific rationale, and a credible study design. The project should also make a convincing case for why the idea is innovative and why the approach is reasonable to explore.
Do applicants need to explain why their idea is innovative?
Yes. The Principal Investigator is expected to explicitly explain what makes the project innovative within the NF field, rather than relying on reviewers to infer novelty.
Who offered this funding opportunity?
The opportunity was offered by the Department of the Army through the U.S. Army Medical Research Acquisition Activity (USAMRAA) under the Neurofibromatosis Research Program (NFRP).
What is the funding opportunity number?
The funding opportunity number is W81XWH-15-NFRP-EHDA.
What CFDA listing is associated with this opportunity?
The CFDA listing associated with this opportunity is 12.420, Military Medical Research and Development.
What type of funding instrument was used?
The instrument type listed includes grants and cooperative agreements.
How many awards were expected and what was the estimated total funding level?
The program anticipated making about eight awards, with an estimated total funding level of $1,280,000.
Was cost sharing or matching required?
No. There was no cost sharing or matching requirement, meaning applicants were not expected to contribute their own funds as a condition of receiving the award.
Who was eligible to apply?
Eligibility was described as unrestricted, meaning it was open to essentially any type of entity, subject to any additional eligibility clarifications contained in the full announcement.
What were the key dates for this opportunity?
The posting date and creation date were May 6, 2015. The original and current closing date was July 27, 2015. The archive date was August 26, 2015.
Is this opportunity still open?
No. Based on the listed closing date (July 27, 2015) and archive date (August 26, 2015), this specific opportunity is no longer open.
What research area does this opportunity fall under?
It was categorized under Science and Technology and other Research and Development, with a focus on neurofibromatosis (NF) research.
What should applicants do if they have trouble accessing the full announcement?
Applicants who had trouble accessing the full announcement were directed to contact the CDMRP Help Desk at 301-682-5507.
How should this award be understood in practical terms?
It is best understood as a catalyst program: it funds carefully conceived, hypothesis-driven NF research that is willing to take informed risks in pursuit of outsized advances, while requiring applicants to clearly demonstrate how their approach breaks new ground.
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