Opportunity Information: Apply for CDC RFA GH15 1622
Apply for CDC RFA GH15 1622
- The Centers for Disease Control and Prevention in the health sector is offering a public funding opportunity titled "Strengthening South Africas Laboratory and Epidemiology Capacity to Detect and Respond to Zoonotic Disease Outbreaks" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.318 Protecting and Improving Health Globally Building and Strengthening Public Health Impact, Systems, Capacity and Securit.
- This funding opportunity was created on May 6, 2015 and posted on May 6, 2015.
- Applicants must submit their applications by Jul 7, 2015 Electronically submitted applications must be submitted no later than 1159 p.m., Eastern Standard Time, on the listed application due date.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $1,000,000.00 to eligible and selected applicants.
- The number of recipients for this funding is limited to 1 candidate(s).
- Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
- University of PretoriaAttn Robert SwanepoelCMEF Laboratory, Floor 3, NWII BuildingLynnwood Road and Roper StreetHatfield Campus, Pretoria 0028, South Africa
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Opportunity Summary:
This grant opportunity (CDC RFA GH15-1622) is a CDC-funded cooperative agreement designed to strengthen South Africa's ability to detect, investigate, and control zoonotic disease outbreaks, meaning infections that spread between animals and people, often through vectors like mosquitoes and ticks or through direct animal-human contact. The overall intent is to reduce illness and deaths by improving how quickly South Africa can spot outbreaks, confirm diagnoses through laboratory testing, share information across agencies, and coordinate a response that protects both human and animal health. The award emphasizes building durable national capacity rather than supporting a one-off study, with a strong focus on surveillance, data systems, and partnerships that allow earlier detection and faster action.
A central theme is expanding laboratory and epidemiology capacity for emerging and re-emerging zoonotic threats. The announcement highlights the need to develop and broaden the country’s ability to identify zoonotic pathogens and respond when unusual clusters or suspected outbreaks occur. This includes establishing or strengthening surveillance systems for infectious diseases transmitted by vectors or through animal-human interactions. It also calls for prioritizing high-impact diseases with significant epidemic potential or high mortality, specifically naming West Nile virus, Rift Valley fever, Crimean-Congo hemorrhagic fever (CCHF), rabies, brucellosis, anthrax, and other emerging vector-borne and zoonotic viruses. In practical terms, the program is aimed at improving routine detection as well as surge readiness, so that field investigations and laboratory confirmation can happen quickly enough to limit spread.
Another major component is real-time reporting and better connectivity between human health and veterinary health information systems. The opportunity stresses implementing near real-time disease reporting and creating interfaces that allow data to move efficiently between public health and animal health sectors. That reflects a One Health approach, where surveillance in humans, livestock, wildlife, and vectors is linked to provide a fuller picture of transmission risk. Alongside this, the FOA places strong emphasis on advancing electronic information systems to improve real-time case reporting and tracking, support regular reporting to local and international health agencies, and enable outbreak prediction through modeling of risk factors for vector-borne and zoonotic diseases. The expectation is not only to collect data, but to make it usable quickly for decision-making, including anticipating where and when outbreaks might occur based on environmental or epidemiologic signals.
The grant also supports pathogen discovery activities in animals, humans, and vectors, particularly when syndromes resemble zoonotic disease but the cause is unclear. This reflects the reality that outbreaks can be missed or misclassified when routine tests do not cover novel or unexpected pathogens. By improving the ability to detect and characterize pathogens across different hosts and vectors, the program aims to close diagnostic gaps and shorten the time between the first warning signs and an accurate identification of the threat.
Coordination and collaboration are treated as essential deliverables. The announcement calls for establishing and/or strengthening collaborations with key partners and coordinating surveillance work with other global health security implementing organizations. This is tied to broader international frameworks, specifically improving implementation of the Global Health Security Agenda (GHSA) and the International Health Regulations (IHR) in South Africa. In other words, the work is meant to align with global standards for preparedness and reporting, and to reinforce the partnerships needed to share information and mount coordinated responses across sectors and institutions.
Finally, the FOA emphasizes generating evidence that can influence policy and practice. It specifically calls for producing burden-of-disease data and scientific evidence demonstrating the importance of vector-borne and zoonotic diseases in Southern Africa, along with evidence on effective ways to rapidly detect, respond to, and control outbreaks. Just as important is dissemination: the program is expected to communicate findings through scientific publications and formal reporting to local and international audiences, including bodies and stakeholders involved in disease control such as WHO, OIE, and South African governmental counterparts referenced in the announcement (for example, public health and agriculture/veterinary authorities). The goal is to ensure that improved surveillance and lab work translates into actionable recommendations for public health professionals, veterinary health professionals, and policymakers.
Administratively, this was a discretionary funding opportunity under a cooperative agreement mechanism, meaning CDC expected to have substantial involvement in the project’s direction and oversight compared to a standard grant. The estimated total funding amount listed was $1,000,000, with one expected award and no cost-sharing requirement. The posting date was May 6, 2015, with an application deadline of July 7, 2015 (11:59 p.m. Eastern Time), and an archive date of July 30, 2015. The eligible applicant identified in the notice is the University of Pretoria (with a specific contact/location listed), and the CDC program contact provided is Laura Eloyan (leloyan@cdc.gov).
Frequently Asked Questions (FAQs)
What is CDC RFA GH15-1622?
CDC RFA GH15-1622 is a CDC-funded cooperative agreement focused on strengthening South Africa's ability to detect, investigate, and control zoonotic disease outbreaks (infections that spread between animals and people).
What is the main purpose of this opportunity?
The purpose is to reduce illness and deaths by improving how quickly South Africa can identify outbreaks, confirm diagnoses through laboratory testing, share information across agencies, and coordinate responses that protect both human and animal health.
What does "zoonotic disease" mean in this context?
In this opportunity, zoonotic diseases are infections that can spread between animals and people, including diseases transmitted by vectors such as mosquitoes and ticks, as well as infections spread through direct animal-human contact.
Is this funding intended for a one-time research study?
No. The award emphasizes building durable national capacity rather than supporting a one-off study, with a strong focus on surveillance, data systems, and partnerships that enable earlier detection and faster action.
What types of capacity improvements are emphasized?
The opportunity emphasizes expanding laboratory and epidemiology capacity for emerging and re-emerging zoonotic threats, including improved surveillance systems, faster field investigations, and timely laboratory confirmation to limit disease spread.
Which diseases are specifically prioritized?
The announcement specifically names West Nile virus, Rift Valley fever, Crimean-Congo hemorrhagic fever (CCHF), rabies, brucellosis, and anthrax, along with other emerging vector-borne and zoonotic viruses.
What kinds of surveillance does the program aim to strengthen?
The program aims to establish or strengthen surveillance systems for infectious diseases transmitted by vectors or through animal-human interactions, improving both routine detection and readiness to surge during unusual clusters or suspected outbreaks.
What does the opportunity mean by "near real-time" disease reporting?
It refers to implementing reporting approaches and electronic systems that make disease information available quickly enough to support timely decision-making, coordination, and outbreak response.
How does the opportunity connect human health and veterinary health systems?
It stresses better connectivity between human health and veterinary health information systems, including creating interfaces so data can move efficiently between public health and animal health sectors.
What is the "One Health" approach referenced in the opportunity?
In this FOA, One Health refers to linking surveillance across humans, livestock, wildlife, and vectors to provide a more complete picture of transmission risk and to support coordinated action.
What role do electronic information systems play in this program?
The FOA emphasizes advancing electronic information systems to improve real-time case reporting and tracking, support regular reporting to local and international health agencies, and enable outbreak prediction through modeling of risk factors.
Does the program include outbreak prediction or modeling?
Yes. The opportunity mentions enabling outbreak prediction through modeling of risk factors for vector-borne and zoonotic diseases, using environmental or epidemiologic signals to anticipate where and when outbreaks might occur.
What are "pathogen discovery" activities in this opportunity?
Pathogen discovery activities are supported in animals, humans, and vectors, particularly when syndromes resemble zoonotic disease but the cause is unclear, helping close diagnostic gaps when routine tests do not identify the pathogen.
Why is pathogen discovery included as a component?
Because outbreaks can be missed or misclassified when routine tests do not cover novel or unexpected pathogens. Strengthening detection and characterization across hosts and vectors is intended to shorten the time from early warning signs to accurate identification.
How important are partnerships and coordination under this award?
Coordination and collaboration are described as essential deliverables, including establishing and/or strengthening collaborations with key partners and coordinating surveillance work with other global health security implementing organizations.
How does this opportunity relate to GHSA and IHR?
The work is intended to support improved implementation of the Global Health Security Agenda (GHSA) and the International Health Regulations (IHR) in South Africa, aligning preparedness and reporting with global standards.
What kinds of evidence or outputs does the FOA expect?
The FOA calls for burden-of-disease data and scientific evidence demonstrating the importance of vector-borne and zoonotic diseases in Southern Africa, as well as evidence on effective ways to rapidly detect, respond to, and control outbreaks.
Are publications and formal reporting part of the expectations?
Yes. The program is expected to communicate findings through scientific publications and formal reporting to local and international audiences, including stakeholders involved in disease control such as WHO, OIE, and relevant South African governmental counterparts.
What type of funding mechanism is this?
This was a discretionary funding opportunity under a cooperative agreement mechanism, meaning CDC expected substantial involvement in the project's direction and oversight compared to a standard grant.
What was the estimated total funding amount and number of awards?
The estimated total funding amount listed was $1,000,000, with one expected award.
Was cost sharing or matching required?
No cost-sharing requirement was stated.
Who was eligible to apply according to the notice?
The eligible applicant identified in the notice is the University of Pretoria.
When was the opportunity posted and what were the key dates?
The posting date was May 6, 2015. The application deadline was July 7, 2015 (11:59 p.m. Eastern Time). The archive date was July 30, 2015.
Who was the CDC program contact for this opportunity?
The CDC program contact provided was Laura Eloyan (leloyan@cdc.gov).
What is the intended impact of improving surveillance and lab capacity?
The intended impact is earlier detection and faster action, including quicker field investigations and laboratory confirmation, to reduce transmission, illness, and deaths from zoonotic and vector-borne outbreaks.
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