Opportunity Information: Apply for W81XWH 11 NFRP EHDA
Apply for W81XWH 11 NFRP EHDA
- The Dept. of the Army USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "DoD Neurofibromatosis Exploration Hypothesis Development Award" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420 Military Medical Research and Development.
- This funding opportunity was created on Apr 28, 2011 and posted on Apr 28, 2011.
- Applicants must submit their applications by Aug 1, 2011. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $300,000.00 to eligible and selected applicants.
- The number of recipients for this funding is limited to 2 candidate(s).
- Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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Opportunity Summary:
The DoD Neurofibromatosis Exploration - Hypothesis Development Award (EHDA) is a research funding opportunity under the Department of the Army, administered through the Congressionally Directed Medical Research Programs (CDMRP) as part of the Neurofibromatosis Research Program (NFRP). It is aimed at jump-starting early-stage, unconventional research ideas in neurofibromatosis (NF) and/or schwannomatosis, specifically ideas that are considered innovative, high-risk, and high-reward. The intent is to create space for new directions that may not yet have the depth of evidence normally expected in more traditional grant mechanisms, but that could lead to major advances if the underlying concept proves out.
This award is designed for the initial exploration of potentially groundbreaking concepts, including those that come from unexpected or serendipitous observations. Rather than demanding a fully built-out hypothesis supported by extensive preliminary results, the mechanism supports exploratory studies that can generate the scientific rationale for a new hypothesis or establish early guiding principles that make an innovative hypothesis credible and testable. Preliminary data are encouraged, because they can strengthen the case for feasibility and novelty, but they are not required, reflecting the program's emphasis on enabling investigators to test bold ideas at an early stage.
A central expectation is that the Principal Investigator clearly explains what makes the proposed work novel and why it should be viewed as innovative within the NF and schwannomatosis research landscape. In other words, applicants are expected to explicitly frame how their approach departs from existing thinking, what new angle it introduces, and how the early results could open a new research path, even if the project is inherently exploratory.
From a funding and administrative standpoint, this opportunity (Funding Opportunity Number W81XWH-11-NFRP-EHDA) was offered as a discretionary program using either a cooperative agreement or grant funding instrument, categorized under science and technology and other research and development. The estimated total funding amount for the announcement was $300,000, with an expectation of making about two awards. There was no cost sharing or matching requirement, which means applicants were not required to provide their own funds to match the award.
Eligibility was described as unrestricted, meaning the competition was open to any type of applicant entity, subject to any additional eligibility clarifications in the full announcement. The posting and creation date for the opportunity was April 28, 2011, with an original and current closing date of August 1, 2011. The opportunity was archived on August 31, 2011. The associated CFDA number listed is 12.420, Military Medical Research and Development.
For applicants needing assistance accessing the full announcement or navigating submission systems, the program provided points of contact through the CDMRP Help Desk and dedicated support lines (including PA HELP and eReceipt HELP) at 301-682-5507 and help@cdmrp.org.
FAQs: DoD Neurofibromatosis Exploration - Hypothesis Development Award (EHDA)
What is the DoD Neurofibromatosis Exploration - Hypothesis Development Award (EHDA)?
The EHDA is a Department of Defense research funding opportunity under the Department of the Army, administered through the Congressionally Directed Medical Research Programs (CDMRP) as part of the Neurofibromatosis Research Program (NFRP). It is intended to jump-start early-stage, unconventional research ideas in neurofibromatosis (NF) and/or schwannomatosis.
What is the main purpose of this award?
The purpose is to create room for new, innovative directions that may not yet have the depth of evidence typically expected in more traditional grant mechanisms, but that could lead to major advances if the underlying concept proves out. The award supports exploratory studies that can build scientific rationale for a new hypothesis or establish early guiding principles that make an innovative hypothesis credible and testable.
What kinds of research projects are a good fit for EHDA?
Projects that are innovative, high-risk, and high-reward, including early-stage concepts and unconventional ideas. The award is designed for the initial exploration of potentially groundbreaking concepts, including those that arise from unexpected or serendipitous observations.
Does the EHDA require a fully developed hypothesis with extensive preliminary data?
No. The mechanism is intended for exploratory work and does not demand a fully built-out hypothesis supported by extensive preliminary results. It supports studies that help generate the scientific rationale for a new hypothesis or establish early principles to make an innovative hypothesis credible and testable.
Are preliminary data required to apply?
No. Preliminary data are encouraged because they can strengthen feasibility and novelty, but they are not required. This reflects the program emphasis on enabling investigators to test bold ideas at an early stage.
What is a key expectation for the Principal Investigator (PI) in the application?
A central expectation is that the PI clearly explains what makes the proposed work novel and why it should be viewed as innovative within the NF and schwannomatosis research landscape. Applicants are expected to explicitly frame how the approach departs from existing thinking, what new angle it introduces, and how early results could open a new research path.
What research areas does the award focus on?
The focus is on research related to neurofibromatosis (NF) and/or schwannomatosis.
What is the Funding Opportunity Number for this announcement?
The Funding Opportunity Number is W81XWH-11-NFRP-EHDA.
Which organization administers this award?
The award is administered through the Congressionally Directed Medical Research Programs (CDMRP) under the Department of the Army, as part of the Neurofibromatosis Research Program (NFRP).
What type of funding instrument was used for this opportunity?
The opportunity was offered as a discretionary program using either a cooperative agreement or a grant funding instrument.
How is this opportunity categorized?
It was categorized under science and technology and other research and development.
How much total funding was estimated for the announcement?
The estimated total funding amount for the announcement was $300,000.
How many awards were expected to be made?
The announcement indicated an expectation of making about two awards.
Is cost sharing or matching required?
No. There was no cost sharing or matching requirement, so applicants were not required to provide their own funds to match the award.
Who was eligible to apply?
Eligibility was described as unrestricted, meaning the competition was open to any type of applicant entity, subject to any additional eligibility clarifications in the full announcement.
When was this opportunity posted?
The posting (and creation) date for the opportunity was April 28, 2011.
What was the application closing date?
The original and current closing date listed for the opportunity was August 1, 2011.
Is this funding opportunity still open?
No. The opportunity was archived on August 31, 2011.
What is the CFDA number associated with this opportunity?
The associated CFDA number listed is 12.420, Military Medical Research and Development.
Where can applicants get help accessing the full announcement or navigating submission systems?
Assistance was provided through the CDMRP Help Desk and dedicated support lines (including PA HELP and eReceipt HELP). The contact phone number listed was 301-682-5507, and the email was help@cdmrp.org.
What support resources were specifically mentioned?
The announcement referenced the CDMRP Help Desk and dedicated support lines, including PA HELP and eReceipt HELP, for help with access and submission-related navigation.
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