Opportunity Information: Apply for W81XWH 11 OCRP TLA
Apply for W81XWH 11 OCRP TLA
- The Dept. of the Army USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "DoD Ovarian Cancer Translational Leverage Award" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420 Military Medical Research and Development.
- This funding opportunity was created on Apr 20, 2011 and posted on Apr 20, 2011.
- Applicants must submit their applications by Aug 18, 2011. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $4,000,000.00 to eligible and selected applicants.
- The number of recipients for this funding is limited to 5 candidate(s).
- Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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Opportunity Summary:
The DoD Ovarian Cancer Translational Leverage Award (TLA), offered through the Department of the Army/USAMRAA under the Ovarian Cancer Research Program (OCRP), is a translational research funding opportunity designed to get more value out of ovarian cancer resources that already exist. The main idea is to reduce waste and speed up progress by supporting projects that make established, human-based ovarian cancer resources more broadly usable, rather than repeatedly recreating similar specimen collections, datasets, or infrastructure in separate labs. In practice, the program is trying to solve a common bottleneck in biomedical research: valuable materials and data are often developed with significant time and expense, but then stay confined to the original investigator or institution, limiting their impact and forcing other teams to duplicate work.
This award specifically targets existing human-based ovarian cancer resources that can be leveraged to address high-impact scientific questions or clear unmet needs in ovarian cancer. The emphasis on "translational" work signals that the resource should help move discoveries toward clinical relevance, such as improving understanding of disease mechanisms, enabling biomarker development, supporting patient stratification, or accelerating evaluation of therapeutic approaches. The opportunity recognizes that generating and maintaining these resources can be costly, and that making them accessible and useful to the broader community often requires additional investment (for example, curation, standardization, documentation, quality control, harmonization of clinical metadata, or building systems that allow other investigators to request and use the resource).
Examples of resources the program is interested in include biorepositories of clinical specimens and tissue banks, epidemiological resources, clinical databases, specialized laboratory expertise that could be shared, large transcriptomic or proteomic datasets, and databases containing clinical data and associated metadata. The focus is not limited to these examples; the common thread is that the resource is human-based, already exists in some form, and can be expanded, curated, or otherwise positioned to benefit multiple research teams and multiple research questions across the ovarian cancer field. The award is intended to encourage maximum use of these assets by shifting them from being lab-bound tools into community-enabling resources.
Administratively, this opportunity was posted on April 20, 2011, with an original and current closing date of August 18, 2011, and an archive date of September 17, 2011. The funding opportunity number is W81XWH-11-OCRP-TLA. The instrument type is a cooperative agreement grant, which generally implies an expectation of substantial involvement or coordination with the funding agency during the project period compared with a standard grant. The total estimated funding listed is $4,000,000, with an expected five awards, and there is no cost-sharing or matching requirement. The CFDA number associated with the program is 12.420 (Military Medical Research and Development). Eligibility is described as unrestricted, meaning it is open to any type of applicant entity, subject to any additional eligibility details that may be provided in the full announcement. For access issues or assistance with the announcement, the CDMRP Help Desk is listed at 301-682-5507.
DoD Ovarian Cancer Translational Leverage Award (TLA) - FAQs
What is the DoD Ovarian Cancer Translational Leverage Award (TLA)?
The Translational Leverage Award (TLA) is a Department of Defense (DoD) funding opportunity under the Ovarian Cancer Research Program (OCRP), administered through the Department of the Army/USAMRAA. It supports translational efforts that increase the value and usability of ovarian cancer research resources that already exist.
What is the main goal of this award?
The main goal is to reduce waste and accelerate progress in ovarian cancer research by investing in established, human-based resources so they can be used more broadly by the research community, rather than having similar collections, datasets, or infrastructure repeatedly recreated in separate labs.
What does "translational" mean in the context of this award?
In this opportunity, "translational" means the resource should help move research toward clinical relevance. Examples include enabling better understanding of disease mechanisms, supporting biomarker development, improving patient stratification, or accelerating evaluation of therapeutic approaches.
What types of projects does the TLA support?
The TLA supports projects that enhance, expand, curate, standardize, document, harmonize, or otherwise improve access to existing human-based ovarian cancer resources so that multiple research teams can use them to address high-impact scientific questions or unmet needs in ovarian cancer.
What is meant by "existing human-based ovarian cancer resources"?
It refers to resources derived from or directly tied to human ovarian cancer, such as clinical specimens, patient-associated data, or human-focused datasets and databases that already exist in some form and can be further developed to benefit the broader community.
What are examples of resources this award is interested in?
Examples listed include biorepositories of clinical specimens and tissue banks, epidemiological resources, clinical databases, specialized laboratory expertise that could be shared, large transcriptomic or proteomic datasets, and databases containing clinical data and associated metadata.
Is the program limited to the listed examples of resources?
No. The listed items are examples. The common thread is that the resource is human-based, already exists, and can be positioned (through expansion, curation, or related improvements) to benefit multiple research teams and multiple research questions in ovarian cancer.
Why does the award emphasize making resources broadly usable?
The opportunity is intended to address a common bottleneck: valuable materials and data are often created at significant cost but remain confined to one investigator or institution. The TLA aims to shift these from lab-bound tools into community-enabling resources to avoid duplication and increase impact.
What kinds of improvements might be funded to make a resource more usable?
The description specifically notes needs such as curation, standardization, documentation, quality control, harmonization of clinical metadata, and building systems that allow other investigators to request and use the resource.
Does the award focus on creating brand-new specimen collections or datasets?
The emphasis is on leveraging and improving established resources rather than repeatedly recreating similar specimen collections, datasets, or infrastructure in separate labs. The intent is to get more value out of what already exists.
Which program and agencies are associated with this award?
The award is offered through the Department of the Army/USAMRAA under the Ovarian Cancer Research Program (OCRP) and is part of the DoD ovarian cancer research funding landscape.
What is the funding opportunity number for this award?
The funding opportunity number is W81XWH-11-OCRP-TLA.
What type of funding instrument is used?
The instrument type is a cooperative agreement grant, which generally implies substantial involvement or coordination with the funding agency during the project period compared with a standard grant.
How much total funding is estimated for this opportunity?
The total estimated funding listed is $4,000,000.
How many awards are expected to be made?
The announcement states that five awards are expected.
Is there a cost-sharing or matching requirement?
No. The opportunity specifies that there is no cost-sharing or matching requirement.
What is the CFDA number associated with this opportunity?
The CFDA number is 12.420 (Military Medical Research and Development).
Who is eligible to apply?
Eligibility is described as unrestricted, meaning it is open to any type of applicant entity, subject to any additional eligibility details that may be provided in the full announcement.
When was this opportunity posted?
The opportunity was posted on April 20, 2011.
What is the application closing date?
The original and current closing date listed is August 18, 2011.
When is the archive date for this opportunity?
The archive date is September 17, 2011.
What should applicants do if they need help accessing the announcement or have access issues?
For access issues or assistance with the announcement, the CDMRP Help Desk is listed at 301-682-5507.
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Previous opportunity: DoD Ovarian Cancer Translational Pilot Award
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